Insulin resistance, cognition and Alzheimer's disease biomarkers: Evidence that CSF Aβ42 moderates the association between insulin resistance and increased CSF tau levels

Authors: Woodfield, Amy, Porter, Tenielle, Gilani, Israa, Noordin, Siti, Li, Qiao-Xin, Collins, Steven, Martins, Ralph N., Maruff, Paul, Masters, Colin L., Rowe, Christopher C., Villemagne, Victor L., Dore, Vincent, Newsholme, Philip, Laws, Simon M., Verdile, Giuseppe

Source: In Neurobiology of Aging June 2022 114:38-48

Antidiabetic effects and mechanisms of action of γ-conglutin from lupin seeds

Authors: Tapadia, Mrunmai, Johnson, Stuart, Utikar, Ranjeet, Newsholme, Philip, Carlessi, Rodrigo

Source: In Journal of Functional Foods December 2021 87

Serum Vitamin D status is associated with increased blastocyst development rate in women undergoing IVF

Authors: Walz, Nikita L., Hinchliffe, Peter M., Soares, Mario J., Dhaliwal, Satvinder S., Newsholme, Philip, Yovich, John L., Keane, Kevin N.

Source: In Reproductive BioMedicine Online December 2020 41(6):1101-1111

Butyrate generated by gut microbiota and its therapeutic role in metabolic syndrome

Authors: Bridgeman, Stephanie C., Northrop, Wendy, Melton, Phillip E., Ellison, Gaewyn C., Newsholme, Philip, Mamotte, Cyril D.S. ^*

Source: In Pharmacological Research October 2020 160

Effects of vitamin D on primary human skeletal muscle cell proliferation, differentiation, protein synthesis and bioenergetics

Authors: Romeu Montenegro, Karina, Carlessi, Rodrigo, Cruzat, Vinicius, Newsholme, Philip

Source: In Journal of Steroid Biochemistry and Molecular Biology October 2019 193

Glutamine deprivation induces metabolic adaptations associated with beta cell dysfunction and exacerbate lipotoxicity

Authors: Carlessi, Rodrigo, Rowlands, Jordan, Ellison, Gaewyn, Helena de Oliveira Alves, Heloisa, Newsholme, Philip, Mamotte, Cyril

Source: In Molecular and Cellular Endocrinology 1 July 2019 491

Use of virus-like particles as a native membrane model to study the interaction of insulin with the insulin receptor

Authors: Sabapathy, Thiru, Helmerhorst, Erik, Bottomley, Steven, Babaeff, Sharon, Munyard, Kylie, Newsholme, Philip, Mamotte, Cyril D.

Source: In BBA - Biomembranes 1 June 2019 1861(6):1204-1212

Nitric Oxide and Redox State Measurements in Pancreatic Beta Cells

Authors: Carlessi, Rodrigo, Cruzat, Vinicius, Chen, Younan, Newsholme, Philip

Source: Methods in molecular biology. 2076:241-254

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622000414&indx=1&recIds=ETOCRN622000414

Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca2+ and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 pancreatic beta cells

Authors: Tapadia, Mrunmai, Carlessi, Rodrigo, Johnson, Stuart, Utikar, Ranjeet, Newsholme, Philip

Source: In Molecular and Cellular Endocrinology 15 January 2019 480:83-96

Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119

Authors: Arifin, Syamsul A., Paternoster, Silvano, Carlessi, Rodrigo, Casari, Ilaria, Ekberg, Jeppe Hvidtfeldt, Maffucci, Tania, Newsholme, Philip, Rosenkilde, Mette M., Falasca, Marco

Source: In BBA - Molecular and Cell Biology of Lipids September 2018 1863(9):1132-1141

Role of the cell membrane interface in modulating production and uptake of Alzheimer's beta amyloid protein

Authors: Bharadwaj, Prashant, Solomon, Tanya, Malajczuk, Chris J., Mancera, Ricardo L., Howard, Mark, Arrigan, Damien W.M., Newsholme, Philip, Martins, Ralph N.

Source: In BBA - Biomembranes September 2018 1860(9):1639-1651

Attenuation of obesity and insulin resistance by fish oil supplementation is associated with improved skeletal muscle mitochondrial function in mice fed a high-fat diet

Authors: Martins, Amanda R., Crisma, Amanda R., Masi, Laureane N., Amaral, Catia L., Marzuca-Nassr, Gabriel N., Bomfim, Lucas H.M., Teodoro, Bruno G., Queiroz, André L., Serdan, Tamires D.A., Torres, Rosangela P., Mancini-Filho, Jorge, Rodrigues, Alice C., Alba-Loureiro, Tatiana C., Pithon-Curi, Tania C., Gorjao, Renata, Silveira, Leonardo R., Curi, Rui, Newsholme, Philip, Hirabara, Sandro M.

Source: In The Journal of Nutritional Biochemistry May 2018 55:76-88

The inhibitory influence of adipose tissue-derived mesenchymal stem cell environment and Wnt antagonism on breast tumour cell lines

Authors: Visweswaran, Malini, Arfuso, Frank, Dilley, Rodney J., Newsholme, Philip, Dharmarajan, Arun

Source: In International Journal of Biochemistry and Cell Biology February 2018 95:63-72

Insulin and IGF-1 receptor autocrine loops are not required for Exendin-4 induced changes to pancreatic β-cell bioenergetic parameters and metabolism in BRIN-BD11 cells

Authors: Rowlands, Jordan, Cruzat, Vinicius, Carlessi, Rodrigo, Newsholme, Philip

Source: In Peptides February 2018 100:140-149

Epigenetic demethylation of sFRPs, with emphasis on sFRP4 activation, leading to Wnt signalling suppression and histone modifications in breast, prostate, and ovary cancer stem cells

Authors: Deshmukh, Abhijeet, Arfuso, Frank, Newsholme, Philip, Dharmarajan, Arun

Source: International journal of biochemistry & cell biology. 109:23-32

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114431683.0x000001&indx=1&recIds=ETOCvdc_100114431683.0x000001

Method Protocols for Metabolic and Functional Analysis of the BRIN-BD11 β-Cell Line: A Preclinical Model for Type 2 Diabetes

Authors: Rowlands, Jordan, Walz, Nikita, Rowles, Joanne E., Keane, Kevin N., Carlessi, Rodrigo, Newsholme, Philip

Source: Methods in molecular biology. 1916:329-340

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN618868703&indx=1&recIds=ETOCRN618868703

The effects of a combined bodyweight-based and elastic bands resistance training, with or without protein supplementation, on muscle mass, signaling and heat shock response in healthy older people

Authors: Krause, Mauricio, Crognale, Domenico, Cogan, Karl, Contarelli, Serena, Egan, Brendan, Newsholme, Philip, De Vito, Giuseppe

Source: Experimental gerontology. 115:104-113

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100074477854.0x000001&indx=1&recIds=ETOCvdc_100074477854.0x000001

PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

Authors: McGonigle, Terence A., Dwyer, Amy R., Greenland, Eloise L., Scott, Naomi M., Keane, Kevin N., Newsholme, Philip, Goodridge, Helen S., Zon, Leonard I., Pixley, Fiona J., Hart, Prue H. ^*

Source: In Experimental Hematology December 2017 56:64-68

Role of epigenetic modulation in cancer stem cell fate

Authors: Deshmukh, Abhijeet, Binju, Mudra, Arfuso, Frank, Newsholme, Philip, Dharmarajan, Arun

Source: In International Journal of Biochemistry and Cell Biology September 2017 90:9-16

UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow–Differentiated Dendritic Cells

Authors: McGonigle, Terence A., Keane, Kevin N., Ghaly, Simon, Carter, Kim W., Anderson, Denise, Scott, Naomi M., Goodridge, Helen S., Dwyer, Amy, Greenland, Eloise, Pixley, Fiona J., Newsholme, Philip, Hart, Prue H.

Source: In The American Journal of Pathology September 2017 187(9):2046-2059