Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins

Authors: Neul, Claudia, Hofmann, Ute, Schaeffeler, Elke, Winter, Stefan, Klein, Kathrin, Giacomini, Kathleen M., Eichelbaum, Michel, Schwab, Matthias, Nies, Anne T.

Source: British journal of pharmacology. 178(6):1459-1474

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Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1

Authors: Chen, Mingqing, Neul, Claudia, Schaeffeler, Elke, Frisch, Franziska, Winter, Stefan, Schwab, Matthias, Koepsell, Hermann, Hu, Shuiying, Laufer, Stefan, Baker, Sharyn D., Sparreboom, Alex, Nies, Anne T.

Source: Clinical pharmacology & therapeutics. 107(1):227-237

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Impact of Membrane Drug Transporters on Resistance to Small-Molecule Tyrosine Kinase Inhibitors

Authors: Neul, Claudia, Schaeffeler, Elke, Sparreboom, Alex, Laufer, Stefan, Schwab, Matthias, Nies, Anne T.

Source: In Trends in Pharmacological Sciences November 2016 37(11):904-932

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