Alginate-based artificial antigen presenting cells expand functional CD8+ T cells with memory characteristics for adoptive cell therapy

Authors: Omotoso, Mary O., Est-Witte, Savannah E., Shannon, Sydney R., Li, Shuyi, Nair, Nina M., Neshat, Sarah Y., Kang, Si-Sim, Tzeng, Stephany Y., Green, Jordan J., Schneck, Jonathan P.

Source: In Biomaterials February 2025 313

The cytokine Meteorin-like inhibits anti-tumor CD8+ T cell responses by disrupting mitochondrial function

Authors: Jackson, Christopher M., Pant, Ayush, Dinalankara, Wikum, Choi, John, Jain, Aanchal, Nitta, Ryan, Yazigi, Eli, Saleh, Laura, Zhao, Liang, Nirschl, Thomas R., Kochel, Christina M., Hwa-Lin Bergsneider, Brandon, Routkevitch, Denis, Patel, Kisha, Cho, Kwang Bog, Tzeng, Stephany, Neshat, Sarah Y., Kim, Young-Hoon, Smith, Barbara J., Ramello, Maria Cecilia, Sotillo, Elena, Wang, Xinnan, Green, Jordan J., Bettegowda, Chetan, Li, Gordon, Brem, Henry, Mackall, Crystal L., Pardoll, Drew M., Drake, Charles G., Marchionni, Luigi, Lim, Michael

Source: In Immunity 13 August 2024 57(8):1864-1877

Polymeric nanoparticle gel for intracellular mRNA delivery and immunological reprogramming of tumors

Authors: Neshat, Sarah Y., Chan, Chun Hei Ryan, Harris, Jawaun, Zmily, Osamah M., Est-Witte, Savannah, Karlsson, Johan, Shannon, Sydney R., Jain, Manav, Doloff, Joshua C., Green, Jordan J., Tzeng, Stephany Y.

Source: In Biomaterials September 2023 300

Targeting strategies for mRNA delivery

Authors: Meyer, Randall A., Neshat, Sarah Y., Green, Jordan J., Santos, Jose Luis, Tuesca, Anthony D.

Source: In Materials Today Advances June 2022 14

Drug delivery strategies in maximizing anti-angiogenesis and anti-tumor immunity

Authors: Lai, Victoria, Neshat, Sarah Y., Rakoski, Amanda, Pitingolo, James, Doloff, Joshua C.

Source: In Advanced Drug Delivery Reviews December 2021 179

Gene delivery for immunoengineering

Authors: Neshat, Sarah Y, Tzeng, Stephany Y, Green, Jordan J

Source: In Current Opinion in Biotechnology December 2020 66:1-10

Biodegradable Polyester Nanoparticle Vaccines Deliver Self‐Amplifying mRNA in Mice at Low Doses

Authors: Wilson, David R., Tzeng, Stephany Y., Rui, Yuan, Neshat, Sarah Y., Conge, Marranne J., Luly, Kathryn M., Wang, Ellen, Firestone, Jessica L., McAuliffe, Josie, Maruggi, Giulietta, Jalah, Rashmi, Johnson, Russell, Doloff, Joshua C., Green, Jordan J.

Source: Advanced therapeutics. 6(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181434536.0x000001&indx=1&recIds=ETOCvdc_100181434536.0x000001

Hydrogel Alginate Considerations for Improved 3D Matrix Stability and Cell Graft Viability and Function in Studying Type 1 Diabetes In Vitro.

Authors: Quiroz, Victor M., Wang, Yuanjia, Rakoski, Amanda I., Kasinathan, Devi, Neshat, Sarah Y., Hollister‐Lock, Jennifer, Doloff, Joshua C.

Source: Advanced Biology; Aug2024, Vol. 8 Issue 8, p1-14, 14p

Subject Terms: MICROPHYSIOLOGICAL systems, TYPE 1 diabetes, POLYMERASE chain reaction, CELL survival, ISLANDS of Langerhans

Crystallization of the Multi-Receptor Tyrosine Kinase Inhibitor Sorafenib for Controlled Long-Term Drug Delivery Following a Single Injection.

Authors: Lai, Victoria¹ (AUTHOR), Neshat, Sarah Y.¹ (AUTHOR), Rakoski, Amanda¹ (AUTHOR), Pitingolo, James¹ (AUTHOR), Sabedra, Johndavid² (AUTHOR), Li, Stephen¹ (AUTHOR), Shodhan, Aryaman¹ (AUTHOR), Doloff, Joshua C.^1,2,3,4,5 (AUTHOR) jcdoloff@jhu.edu

Source: Cellular & Molecular Bioengineering. Oct2021, Vol. 14 Issue 5, p471-486. 16p.

Subject Terms: *PROTEIN-tyrosine kinase inhibitors, *INJECTIONS, *TRIPLE-negative breast cancer, *CONTROLLED drugs, *X-ray powder diffraction, *EPHRIN receptors

The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits and humans.

Authors: Doloff, Joshua C., Veiseh, Omid, de Mezerville, Roberto, Sforza, Marcos, Perry, Tracy Ann, Haupt, Jennifer, Jamiel, Morgan, Chambers, Courtney, Nash, Amanda, Aghlara-Fotovat, Samira, Stelzel, Jessica L., Bauer, Stuart J., Neshat, Sarah Y., Hancock, John, Romero, Natalia Araujo, Hidalgo, Yessica Elizondo, Leiva, Isaac Mora, Munhoz, Alexandre Mendonça, Bayat, Ardeshir, Kinney, Brian M.

Source: Nature Biomedical Engineering; Oct2021, Vol. 5 Issue 10, p1115-1130, 16p

Liver Disease: Induction, Progression, Immunological Mechanisms, and Therapeutic Interventions.

Authors: Neshat, Sarah Y.¹ (AUTHOR) sarahneshat@jhmi.edu, Quiroz, Victor M.¹ (AUTHOR) vquiroz2@jhmi.edu, Wang, Yuanjia¹ (AUTHOR) wgyuanjia@gmail.com, Tamayo, Sebastian¹ (AUTHOR) stamayo2@jhu.edu, Doloff, Joshua C.^1,2,3 (AUTHOR) jcdoloff@jhu.edu

Source: International Journal of Molecular Sciences. Jul2021, Vol. 22 Issue 13, p6777-6777. 1p.

Subject Terms: *LIVER diseases, *CIRRHOSIS of the liver, *CHRONIC hepatitis B, *MESENCHYMAL stem cells, *LIVER failure, *ASCITIC fluids

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Improvement of Islet Engrafts via Treg Induction Using Immunomodulating Polymeric Tolerogenic Microparticles

Authors: Neshat, Sarah Y., Bauer, Stuart J., Rhodes, Kelly R., Quiroz, Victor M., Wong, Valerie W., Lowmaster, Shirley M., Tzeng, Stephany Y., Green, Jordan J., Doloff, Joshua C.

Source: ACS Biomaterials Science & Engineering; 20230101, Issue: Preprints

Bioengineered particles expand myelin-specific regulatory T cells and reverse autoreactivity in a mouse model of multiple sclerosis.

Authors: Rhodes, Kelly R.^1,2, Tzeng, Stephany Y.^1,2, Iglesias, Marcos³, Dongwoo Lee^1,2, Storm, Kaitlyn^1,2, Neshat, Sarah Y.^1,2, Van Dyke, Derek^2,4, Lowmaster, Shirley M.^1,2,3, Spangler, Jamie B.^{1,2,4,5,6,7,8}, Raimondi, Giorgio³, Green, Jordan J.^{1,2,4,5,6,7,9,10} green@jhu.edu

Source: Science Advances. 6/2/2023, Vol. 9 Issue 22, p1-13. 13p.