Comparability of Foslevodopa/Foscarbidopa Pharmacokinetics in Healthy Asian and White Participants

Authors: Rosebraugh, Matthew, Neenan, Melina, Facheris, Maurizio

Source: Clinical pharmacology in drug development. 12(4):407-415

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181678556.0x000001&indx=1&recIds=ETOCvdc_100181678556.0x000001

Bioequivalence of Elagolix/Estradiol/Norethindrone Acetate Fixed‐Dose Combination Product: Phase 1 Results in Healthy Pre‐ and Postmenopausal Women.

Authors: Chen, Mong‐Jen, Marroum, Patrick, Chiu, Yi‐Lin, Neenan, Melina, Mostafa, Nael M., Shebley, Mohamad

Source: Clinical Pharmacology in Drug Development; Jun2024, Vol. 13 Issue 6, p601-610, 10p

Subject Terms: LUTEINIZING hormone releasing hormone receptors, POSTMENOPAUSE, MENORRHAGIA, ESTRADIOL, MORNINGNESS-Eveningness Questionnaire, ACETATES

Metabolite profiling of foslevodopa/foscarbidopa in plasma of healthy human participants by LC‐HRMS indicates no major differences compared to administration of levodopa/carbidopa intestinal gel.

Authors: Savaryn, John P., Smith, Richard L., Rosebraugh, Matthew, Neenan, Melina, Burton, Richard, Marsh, Kennan, Wagner, David

Source: Pharmacology Research & Perspectives; Apr2024, Vol. 12 Issue 2, p1-11, 11p

Subject Terms: CARBIDOPA, SUBCUTANEOUS infusions, INTESTINES, NASOENTERAL tubes, MASS spectrometry, DOPA, MICROBIAL metabolites

A Phase-I pharmacokinetic, safety and food-effect study on flubentylosin, a novel analog of Tylosin-A having potent anti-Wolbachia and antifilarial activity.

Authors: Alami, Negar, Carter, David C., Kwatra, Nisha V., Zhao, Weihan, Snodgrass, Linda, Porcalla, Ariel R., Klein, Cheri E., Cohen, Daniel E., Gallenberg, Loretta, Neenan, Melina, Carr, Robert A., Marsh, Kennan C., Kempf, Dale J.

Source: PLoS Neglected Tropical Diseases; 7/10/2023, Vol. 17 Issue 7, p1-18, 18p

Subject Terms: PARASITIC diseases, PHARMACOKINETICS, ONCHOCERCIASIS, ADVERSE health care events, FILARIASIS

Geographic Terms: AFRICA

Foslevodopa/Foscarbidopa Is Well Tolerated and Maintains Stable Levodopa and Carbidopa Exposure Following Subcutaneous Infusion.

Authors: Rosebraugh, Matthew, Liu, Wei, Neenan, Melina, Facheris, Maurizio F.

Source: Journal of Parkinson's Disease; 2021, Vol. 11 Issue 4, p1695-1702, 8p

Subject Terms: SUBCUTANEOUS infusions, DOPA, CARBIDOPA, PARKINSON'S disease, ADULTS

Geographic Terms: UNITED States

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