Pharmacogenetics as part of recommended precision medicine for tuberculosis treatment in African populations: Could it be a reality?

Authors: Oelofse, Carola, Ndong Sima, Carene Anne Alene, Möller, Marlo, Uren, Caitlin

Source: Clinical and translational science. 16(7):1101-1112

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187363079.0x000001&indx=1&recIds=ETOCvdc_100187363079.0x000001

Methodologies underpinning polygenic risk scores estimation: a comprehensive overview.

Authors: Ndong Sima, Carene Anne Alene¹ (AUTHOR), Step, Kathryn¹ (AUTHOR), Swart, Yolandi¹ (AUTHOR), Schurz, Haiko¹ (AUTHOR), Uren, Caitlin^1,2 (AUTHOR), Möller, Marlo^1,2 (AUTHOR) marlom@sun.ac.za

Source: Human Genetics. Nov2024, Vol. 143 Issue 11, p1265-1280. 16p.

Subject Terms: *GENOME-wide association studies, *GENETIC variation, *THERAPEUTICS, *TREATMENT effectiveness, *PREDICTIVE validity, *INDIVIDUALIZED medicine, *GENEALOGY

The immunogenetics of tuberculosis (TB) susceptibility.

Authors: Ndong Sima, Carene Anne Alene¹ (AUTHOR), Smith, Dayna¹ (AUTHOR), Petersen, Desiree C.¹ (AUTHOR), Schurz, Haiko¹ (AUTHOR), Uren, Caitlin^1,2 (AUTHOR), Möller, Marlo^1,2 (AUTHOR) marlom@sun.ac.za

Source: Immunogenetics. Jun2023, Vol. 75 Issue 3, p215-230. 16p.

Subject Terms: *TUBERCULOSIS, *MYCOBACTERIUM tuberculosis, *DISEASE risk factors, *THERAPEUTICS, *MONOGENIC & polygenic inheritance (Genetics), *IMMUNOGENETICS

Advancing pharmacogenetics research in Africa: the “Project Africa GRADIENT” initiative

Authors: Ndong Sima, Carene Anne Alene, Othman, Houcemeddine, Möller, Marlo

Source: In Drug Discovery Today May 2024 29(5)

Dynamic and features of SARS-CoV-2 infection in Gabon.

Authors: Mveang Nzoghe, Amandine, Padzys, Guy-Stephan, Maloupazoa Siawaya, Anicet Christel, Kandet Yattara, Marisca, Leboueny, Marielle, Avome Houechenou, Rotimi Myrabelle, Bongho, Eliode Cyrien, Mba-Mezeme, Cedrick, Mvoundza Ndjindji, Ofilia, Biteghe-Bi-Essone, Jean Claude, Boulende, Alain, Essone, Paulin N., Ndong Sima, Carene Anne Alene, Minkobame, Ulysse, Zang Eyi, Carinne, Ndeboko, Bénédicte, Voloc, Alexandru, Meye, Jean-François, Ategbo, Simon, Djoba Siawaya, Joel Fleury

Source: Scientific Reports; 5/6/2021, Vol. 11 Issue 1, p1-10, 10p

Subject Terms: COVID-19, IMMUNOGLOBULINS, LEUKOCYTES, CHRONIC diseases

Geographic Terms: GABON