Single-epitope T cell–based vaccine protects against SARS-CoV-2 infection in a preclinical animal model

Authors: Takuya Tada, Ju-Yi Peng, Belinda M. Dcosta, Nathaniel R. Landau

Source: JCI Insight, Vol 8, Iss 7 (2023)

Subject Terms: COVID-19, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/550e7accedfb47f8955e0c5aae11bfe3

Delta-Omicron recombinant escapes therapeutic antibody neutralization

Authors: Ralf Duerr, Hao Zhou, Takuya Tada, Dacia Dimartino, Christian Marier, Paul Zappile, Guiqing Wang, Jonathan Plitnick, Sara B. Griesemer, Roxanne Girardin, Jessica Machowski, Sean Bialosuknia, Erica Lasek-Nesselquist, Samuel L. Hong, Guy Baele, Meike Dittmann, Mila B. Ortigoza, Prithiv J. Prasad, Kathleen McDonough, Nathaniel R. Landau, Kirsten St George, Adriana Heguy

Source: iScience, Vol 26, Iss 2, Pp 106075- (2023)

Subject Terms: biological sciences, immunology, immunity, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223001529; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/585eec9eafc5429bbcaa9a950f5d24d1

Prophylaxis and treatment of SARS-CoV-2 infection by an ACE2 receptor decoy in a preclinical animal model

Authors: Takuya Tada, Belinda M. Dcosta, Hao Zhou, Nathaniel R. Landau

Source: iScience, Vol 26, Iss 2, Pp 106092- (2023)

Subject Terms: Drugs, Virology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223001694; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/e252738bdcd645f3aa65533b3a95eb93

Directly injected lentiviral vector–based T cell vaccine protects mice against acute and chronic viral infection

Authors: Takuya Tada, Thomas D. Norton, Rebecca Leibowitz, Nathaniel R. Landau

Source: JCI Insight, Vol 7, Iss 18 (2022)

Subject Terms: Immunology, Vaccines, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/3bfe8cd57d9b48468cad25ba2d2392ac

Antibody isotype diversity against SARS-CoV-2 is associated with differential serum neutralization capacities

Authors: Maria G. Noval, Maria E. Kaczmarek, Akiko Koide, Bruno A. Rodriguez-Rodriguez, Ping Louie, Takuya Tada, Takamitsu Hattori, Tatyana Panchenko, Larizbeth A. Romero, Kai Wen Teng, Andrew Bazley, Maren de Vries, Marie I. Samanovic, Jeffrey N. Weiser, Ioannis Aifantis, Joan Cangiarella, Mark J. Mulligan, Ludovic Desvignes, Meike Dittmann, Nathaniel R. Landau, Maria Aguero-Rosenfeld, Shohei Koide, Kenneth A. Stapleford

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/431b486be8244906b88b8f8c1a505e1f

Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy

Authors: Lissenya B. Argueta, Lauretta A. Lacko, Yaron Bram, Takuya Tada, Lucia Carrau, André Figueiredo Rendeiro, Tuo Zhang, Skyler Uhl, Brienne C. Lubor, Vasuretha Chandar, Cristianel Gil, Wei Zhang, Brittany J. Dodson, Jeroen Bastiaans, Malavika Prabhu, Sean Houghton, David Redmond, Christine M. Salvatore, Yawei J. Yang, Olivier Elemento, Rebecca N. Baergen, Benjamin R. tenOever, Nathaniel R. Landau, Shuibing Chen, Robert E. Schwartz, Heidi Stuhlmann

Source: iScience, Vol 25, Iss 5, Pp 104223- (2022)

Subject Terms: Health sciences, Immunology, Transcriptomics, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S258900422200493X; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/10e8c8bb49714f07ba4f189eb87775e5

Neutralization of SARS-CoV-2 Variants by mRNA and Adenoviral Vector Vaccine-Elicited Antibodies

Authors: Takuya Tada, Hao Zhou, Marie I. Samanovic, Belinda M. Dcosta, Amber Cornelius, Ramin S. Herati, Mark J. Mulligan, Nathaniel R. Landau

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: SARS-CoV-2 variant, Delta, Delta plus, Lambda, BNT162b2, mRNA-1273, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.797589/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/445e7b65f7b844738afa2a02748999f8

High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens

Authors: Claudio Counoupas, Paco Pino, Alberto O. Stella, Caroline Ashley, Hannah Lukeman, Nayan D. Bhattacharyya, Takuya Tada, Stephanie Anchisi, Charles Metayer, Jacopo Martinis, Anupriya Aggarwal, Belinda M. Dcosta, Warwick J. Britton, Joeri Kint, Maria J. Wurm, Nathaniel R. Landau, Megan Steain, Stuart G. Turville, Florian M. Wurm, Sunil A. David, James A. Triccas

Source: Microbiology Spectrum, Vol 10, Iss 1 (2022)

Subject Terms: COVID-19, vaccination, subunit vaccine, variant, adjuvant, immune response, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/215dbedfcba04207b2b7b97f024ad384

Partial resistance of SARS-CoV-2 Delta variants to vaccine-elicited antibodies and convalescent sera

Authors: Takuya Tada, Hao Zhou, Belinda M. Dcosta, Marie I. Samanovic, Mark J. Mulligan, Nathaniel R. Landau

Source: iScience, Vol 24, Iss 11, Pp 103341- (2021)

Subject Terms: Biological sciences, Immune response, Virology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004221013109; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/4a04efff253c4798a3fb65a02845653c

B.1.526 SARS-CoV-2 Variants Identified in New York City are Neutralized by Vaccine-Elicited and Therapeutic Monoclonal Antibodies

Authors: Hao Zhou, Belinda M. Dcosta, Marie I. Samanovic, Mark J. Mulligan, Nathaniel R. Landau, Takuya Tada

Source: mBio, Vol 12, Iss 4 (2021)

Subject Terms: SARS-CoV-2, neutralization, B.1.526, spike protein, Pfizer BNT162b2, Moderna mRNA-1273, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/d27f99fff4a1464d856ab08b87f4e537

Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes

Authors: Takuya Tada, Belinda M. Dcosta, Marie I. Samanovic, Ramin S. Herati, Amber Cornelius, Hao Zhou, Ada Vaill, Wes Kazmierski, Mark J. Mulligan, Nathaniel R. Landau

Source: mBio, Vol 12, Iss 3 (2021)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/cc8f89b646aa4935b60240d6b20c5db4

Honing the T cell response to HIV: Turning off the noise

Authors: Nathaniel R. Landau

Source: EBioMedicine, Vol 64, Iss , Pp 103217- (2021)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396421000104; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/542fd59f39e4415c9a27716e32fe8004

Resistance of SARS-CoV-2 Omicron BA.1 and BA.2 Variants to Vaccine-Elicited Sera and Therapeutic Monoclonal Antibodies

Authors: Hao Zhou, Belinda M. Dcosta, Nathaniel R. Landau, Takuya Tada

Source: Viruses, Vol 14, Iss 6, p 1334 (2022)

Subject Terms: SARS-CoV-2 variants, COVID-19, Omicron BA.2, monoclonal antibodies, spike protein, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/6/1334; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/558162fd02e64f94a288297769ec17e3

Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5

Authors: Kayan Tam, Megan Schultz, Tamara Reyes-Robles, Bénédicte Vanwalscappel, Joshua Horton, Francis Alonzo, Beili Wu, Nathaniel R. Landau, Victor J. Torres

Source: mBio, Vol 7, Iss 6 (2016)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/2d3a8571d04d47e2af728faf7069e218

Checkpoint inhibitor-expressing lentiviral vaccine suppresses tumor growth in preclinical cancer models

Authors: Thomas D Norton, Takuya Tada, Rebecca Leibowitz, Nathaniel R Landau

Source: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/12/4/e008761.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/6466ce6511424bd0ae6f35dc39cca1f2

Variable susceptibility of intestinal organoid-derived monolayers to SARS-CoV-2 infection.

Authors: Kyung Ku Jang, Maria E Kaczmarek, Simone Dallari, Ying-Han Chen, Takuya Tada, Jordan Axelrad, Nathaniel R Landau, Kenneth A Stapleford, Ken Cadwell

Source: PLoS Biology, Vol 20, Iss 3, p e3001592 (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/20451bc3943b4d15a52f7d199581e70f

SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells.

Authors: Ruonan Zhang, Nicolin Bloch, Laura A Nguyen, Baek Kim, Nathaniel R Landau

Source: PLoS ONE, Vol 9, Iss 2, p e89558 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089558&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/9d1b9dfe10ea42ff909ab0337e5a8f78

A DNA sequence recognition loop on APOBEC3A controls substrate specificity.

Authors: Eric C Logue, Nicolin Bloch, Erica Dhuey, Ruonan Zhang, Ping Cao, Cecile Herate, Lise Chauveau, Stevan R Hubbard, Nathaniel R Landau

Source: PLoS ONE, Vol 9, Iss 5, p e97062 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4020817?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c4e98eb74fb7470498c195b84b4cddac

Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase.

Authors: Iñigo Narvaiza, Daniel C Linfesty, Benjamin N Greener, Yoshiyuki Hakata, David J Pintel, Eric Logue, Nathaniel R Landau, Matthew D Weitzman

Source: PLoS Pathogens, Vol 5, Iss 5, p e1000439 (2009)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19461882/?tool=EBI; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/c9be6e30441e4dc4b3b23d56c804e04b