Identification of unique binding mode anti-NTF3 antibodies from a novel long VH CDR3 phage display library

Authors: Stacey E. Chin, Pablo Gallego, Anna Aagaard, Sara Carmen, Nathalie Barrett, Marcin Wolny, Sophie Cloarec, Judy Paterson, Rohan Sivapalan, James Hunt, Thomas V. Murray, Tracy Delaney, Tove Sjögren, Frances Neal

Source: SLAS Discovery, Vol 31, Iss , Pp 100216- (2025)

Subject Terms: Neurotrophins, Phage display, X ray crystallography, Antibody, VH CDR3, Medicine (General), R5-920, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2472555225000097; https://doaj.org/toc/2472-5552

Access URL: https://doaj.org/article/595c54d765924d72a721287af6616ee2

Targeted protein degradation using chimeric human E2 ubiquitin-conjugating enzymes

Authors: Jonathan D. Taylor, Nathalie Barrett, Sergio Martinez Cuesta, Katelyn Cassidy, Fiona Pachl, James Dodgson, Radhika Patel, Tuula M. Eriksson, Aidan Riley, Matthew Burrell, Christin Bauer, D. Gareth Rees, Raffaello Cimbro, Andrew X. Zhang, Ralph R. Minter, James Hunt, Sandrine Legg

Source: Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/82c3864e38134c29b42485f93454e6e6

KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe

Authors: Nicolas Bery, Sandrine Legg, Judit Debreczeni, Jason Breed, Kevin Embrey, Christopher Stubbs, Paulina Kolasinska-Zwierz, Nathalie Barrett, Rose Marwood, Jo Watson, Jon Tart, Ross Overman, Ami Miller, Christopher Phillips, Ralph Minter, Terence H. Rabbitts

Source: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d60832bba2a448e1bd87fa3edb2b14fd

Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses.

Authors: Rachel Grimley, Oxana Polyakova, Jessica Vamathevan, Joanne McKenary, Brian Hayes, Champa Patel, Janet Smith, Angela Bridges, Andrew Fosberry, Anshu Bhardwaja, Bernadette Mouzon, Chun-Wa Chung, Nathalie Barrett, Nicola Richmond, Sundip Modha, Roberto Solari

Source: PLoS ONE, Vol 7, Iss 7, p e39847 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22792191/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/554910ddac3e4c48ab605416698c2ab9

Correction: Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses.

Authors: Rachel Grimley, Oxana Polyakova, Jessica Vamathevan, Joanne McKenary, Brian Hayes, Champa Patel, Janet Smith, Angela Bridges, Andrew Fosberry, Anshu Bhardwaja, Bernadette Mouzon, Chun-Wa Chung, Nathalie Barrett, Nicola Richmond, Sundip Modha, Roberto Solari

Source: PLoS ONE, Vol 7, Iss 9 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3471978; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b87abd360cbe4242978c39198c55f937

Use of Mixed Methods in the Science of Hydrological Extremes: What Are Their Contributions?

Authors: Raymond Kabo, Marc-André Bourgault, Jean François Bissonnette, Nathalie Barrette, Louis Tanguay

Source: Hydrology, Vol 10, Iss 6, p 130 (2023)

Subject Terms: epistemology, hydrological extremes, science, uncertainty, complexity, mixed methods, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2306-5338/10/6/130; https://doaj.org/toc/2306-5338

Access URL: https://doaj.org/article/90155fe9344b4d478c062fd9ad7e9c39

Fragment-Based Discovery of Low-Micromolar ATAD2Bromodomain Inhibitors.

Authors: Emmanuel H. Demont, Chun-wa Chung, RebeccaC. Furze, Paola Grandi, Anne-Marie Michon, Chris Wellaway, Nathalie Barrett, Angela M. Bridges, PeterD. Craggs, Hawa Diallo, David P. Dixon, Clement Douault, Amanda J. Emmons, EmmaJ. Jones, Bhumika V. Karamshi, Kelly Locke, Darren J. Mitchell, BernadetteH. Mouzon, Rab K. Prinjha, Andy D. Roberts

Source: Journal of Medicinal Chemistry; Jul2015, Vol. 58 Issue 14, p5649-5673, 25p