Nanoengineered cargo with targeted in vivo Foxo3 gene editing modulated mitophagy of chondrocytes to alleviate osteoarthritis

Authors: Manyu Chen, Yuan Liu, Quanying Liu, Siyan Deng, Yuhan Liu, Jiehao Chen, Yaojia Zhou, Xiaolin Cui, Jie Liang, Xingdong Zhang, Yujiang Fan, Qiguang Wang, Bin Shen

Source: Acta Pharmaceutica Sinica B, Vol 15, Iss 1, Pp 571-591 (2025)

Subject Terms: Osteoarthritis, Mitophagy, Nanoengineered cargo, In vivo Foxo3 gene editing, Cartilage regeneration, Injectable hydrogel microspheres, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383524004659; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/716c86d98a8747ddbd2f8ed436222d66