Directed Photochemically Mediated Nickel-Catalyzed (Hetero)arylation of Aliphatic C—H Bonds

Authors: Simons, R. Thomas, Nandakumar, Meganathan, Kwon, Kitae, Ayer, Suraj K., Venneti, Naresh M., Roizen, Jennifer L.

Source: Journal of the American Chemical Society. 145(7):3882-3890

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Strategies to Generate Nitrogen-centered Radicals That May Rely on Photoredox Catalysis: Development in Reaction Methodology and Applications in Organic Synthesis

Authors: Kwon, Kitae, Simons, R. Thomas, Nandakumar, Meganathan, Roizen, Jennifer L.

Source: Chemical reviews. 122(2):2353-2428

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Ring‐Opening Lithiation–Borylation of 2‐Trifluoromethyl Oxirane: A Route to Versatile Tertiary Trifluoromethyl Boronic Esters

Authors: Nandakumar, Meganathan, Rubial, Belén, Noble, Adam, Myers, Eddie L., Aggarwal, Varinder K.

Source: Angewandte Chemie. 132(3):1203-1207

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Structure Activity of β‑Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity.

Authors: Ghoshal, Anirban, Asressu, Kesatebrhan Haile, Hossain, Mohammad Anwar, Brown, Peter J., Nandakumar, Meganathan, Vala, Anand, Merten, Eric M., Sears, John D., Law, Isabella, Burdick, Jane E., Morales, Noah L., Perveen, Sumera, Pearce, Kenneth H., Popov, Konstantin I., Moorman, Nathaniel J., Heise, Mark T., Willson, Timothy M.

Source: Journal of Medicinal Chemistry; 9/26/2024, Vol. 67 Issue 18, p16505-16532, 28p

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of ChikungunyansP2 Cysteine Protease with Antialphavirus Activity

Authors: Ghoshal, Anirban, Asressu, Kesatebrhan Haile, Hossain, Mohammad Anwar, Brown, Peter J., Nandakumar, Meganathan, Vala, Anand, Merten, Eric M., Sears, John D., Law, Isabella, Burdick, Jane E., Morales, Noah L., Perveen, Sumera, Pearce, Kenneth H., Popov, Konstantin I., Moorman, Nathaniel J., Heise, Mark T., Willson, Timothy M.

Source: Journal of Medicinal Chemistry; September 2024, Vol. 67 Issue: 18 p16505-16532, 28p

Enantiodivergent Synthesis of Allenes by Point‐to‐Axial Chirality Transfer

Authors: Armstrong, Roly J., Nandakumar, Meganathan, Dias, Rafael M. P., Noble, Adam, Myers, Eddie L., Aggarwal, Varinder K.

Source: Angewandte Chemie international edition. 57(27):8203-8208

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Synthesis and photophysical properties of benzo[c]thiophene, p-phenylene-, triphenylamine-, and pyrene-based vinylenes

Authors: Nandakumar, Meganathan, Sankar, Elumalai, Mohanakrishnan, Arasambattu K.

Source: Synthetic communications. 46(22):1810-1819

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Dual Inhibition of Mycobacterium tuberculosis and the Host TGFBR1 by an Anilinoquinazoline.

Authors: Nandakumar, Meganathan, Ollodart, Anja, Fleck, Neil, Kapadia, Nirav R., Frando, Andrew, Boradia, Vishant, Smith, Jeffery L., Chen, Junxi, Zuercher, William J., Willson, Timothy M., Grundner, Christoph

Source: Journal of Medicinal Chemistry; 11/9/2023, Vol. 66 Issue 21, p14724-14734, 11p

Dual Inhibition of Mycobacterium tuberculosisand the Host TGFBR1 by an Anilinoquinazoline

Authors: Nandakumar, Meganathan, Ollodart, Anja, Fleck, Neil, Kapadia, Nirav R., Frando, Andrew, Boradia, Vishant, Smith, Jeffery L., Chen, Junxi, Zuercher, William J., Willson, Timothy M., Grundner, Christoph

Source: Journal of Medicinal Chemistry; November 2023, Vol. 66 Issue: 21 p14724-14734, 11p

Studies on the Phthalidation of Heteroarenes: A Facile Preparation of 3-(Heteroaryl)phthalides via Triflic Acid Mediated Phthalidation

Authors: Nandakumar, Meganathan, Sankar, Elumalai, Mohanakrishnan, Arasambattu

Source: Synlett. 25(4):509-514

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Oxidative Cleavage of 1, 3-Disubstituted Benzo[c]furans with Activated Manganese­ Dioxide: A Facile Preparation of 1, 2-Di(het)aroylbenzenes

Authors: Sivasakthikumaran, Ramakrishnan, Nandakumar, Meganathan, Mohanakrishnan, Arasambattu

Source: Synlett. 25(13):1896-1900

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Chemoproteomic Profiling of C. albicansfor Characterization of Antifungal Kinase Inhibitors

Authors: Shirley, David J., Nandakumar, Meganathan, Cabrera, Aurora, Yiu, Bonnie, Puumala, Emily, Liu, Zhongle, Robbins, Nicole, Whitesell, Luke, Smith, Jeffrey L., Lyons, Scott, Mordant, Angie L., Herring, Laura E., Graves, Lee M., Couñago, Rafael M., Drewry, David H., Cowen, Leah E., Willson, Timothy M.

Source: Journal of Medicinal Chemistry; 20250101, Issue: Preprints

Synthesis and photophysical properties of benzo[ c ]thiophene, p -phenylene-, triphenylamine-, and pyrene-based vinylenes.

Authors: Nandakumar, Meganathan¹ (AUTHOR), Sankar, Elumalai¹ (AUTHOR), Mohanakrishnan, Arasambattu K.¹ (AUTHOR) mohan_67@hotmail.com

Source: Synthetic Communications. 2016, Vol. 46 Issue 22, p1810-1819. 10p. 9 Diagrams, 3 Graphs.

Subject Terms: *THIOPHENES, *CHEMICAL synthesis, *TRIPHENYLAMINE, *PYRENE, *CHEMICAL reactions, *ALDEHYDES

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Crystal structures of three 1-oxo-1,2-dihydro-naphthalene derivatives: dimethyl 4-(4-methoxy-phenyl)-2-(4-methylphenyl)-1-oxo-1,2-dihydro-naphthalene-2,3-dicarboxylate, dimethyl 1-oxo-2-(pyren-4-yl)-4-(thiophen-2-yl)-1,2-dihydro-naphthalene-2,3-dicarboxylate and ethyl 1-oxo-2-phenyl-2,4-bis(thiophen-2-yl)-1,2-dihydro-naphthalene-3-carboxylate

Authors: Gopinath, S., Narayanan, P., Sethusankar, K., Karunakaran, Jeyachandran, Nandakumar, Meganathan, Mohanakrishnan, Arasambattu K.

Source: Acta Crystallographica Section E: Crystallographic Communications; Feb2017, Vol. 73 Issue 2, p177-182, 26p

Subject Terms: NAPHTHALENE derivatives, CARBOXYLATE derivatives, THIOPHENES, CRYSTAL structure, CARBONYL compounds