RAAS-deficient organoids indicate delayed angiogenesis as a possible cause for autosomal recessive renal tubular dysgenesis

Authors: Naomi Pode-Shakked, Megan Slack, Nambirajan Sundaram, Ruth Schreiber, Kyle W. McCracken, Benjamin Dekel, Michael Helmrath, Raphael Kopan

Source: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/21f90e81a5fe4cb28b323e95f795a5d6

Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport

Authors: Heather A. McCauley, Andrea L. Matthis, Jacob R. Enriquez, Jonah T. Nichol, J. Guillermo Sanchez, William J. Stone, Nambirajan Sundaram, Michael A. Helmrath, Marshall H. Montrose, Eitaro Aihara, James M. Wells

Source: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/50edefa8b4244558bced763cdc66baa9

Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids

Authors: Meghan M. Capeling, Michael Czerwinski, Sha Huang, Yu-Hwai Tsai, Angeline Wu, Melinda S. Nagy, Benjamin Juliar, Nambirajan Sundaram, Yang Song, Woojin M. Han, Shuichi Takayama, Eben Alsberg, Andres J. Garcia, Michael Helmrath, Andrew J. Putnam, Jason R. Spence

Source: Stem Cell Reports, Vol 12, Iss 2, Pp 381-394 (2019)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671118305204; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/1de97d1717354c6686b5f5c27888e4d5

An Organoid-Based Preclinical Model of Human Gastric CancerSummary

Authors: Nina G. Steele, Jayati Chakrabarti, Jiang Wang, Jacek Biesiada, Loryn Holokai, Julie Chang, Lauren M. Nowacki, Jennifer Hawkins, Maxime Mahe, Nambirajan Sundaram, Noah Shroyer, Mario Medvedovic, Michael Helmrath, Syed Ahmad, Yana Zavros

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 161-184 (2019)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X18301309; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/0b3344e92de44f69ab10a3fbb7d5b624

Evaluation of transplantation sites for human intestinal organoids.

Authors: Akaljot Singh, Holly M Poling, Nambirajan Sundaram, Nicole Brown, James M Wells, Michael A Helmrath

Source: PLoS ONE, Vol 15, Iss 8, p e0237885 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4df5319f91e4406ea55d08281fbc7442

Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells

Authors: Kodandaramireddy Nalapareddy, Kalpana J. Nattamai, Rupali S. Kumar, Rebekah Karns, Kathryn A. Wikenheiser-Brokamp, Leesa L. Sampson, Maxime M. Mahe, Nambirajan Sundaram, Mary-Beth Yacyshyn, Bruce Yacyshyn, Michael A. Helmrath, Yi Zheng, Hartmut Geiger

Source: Cell Reports, Vol 18, Iss 11, Pp 2608-2621 (2017)

Subject Terms: aging, regeneration, intestinal stem cells, Wnt signaling, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717302541; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/c6980a428dc64392a7a39bc4956b9d03

Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection.

Authors: Loryn Holokai, Jayati Chakrabarti, Taylor Broda, Julie Chang, Jennifer A Hawkins, Nambirajan Sundaram, Lydia E Wroblewski, Richard M Peek, Jiang Wang, Michael Helmrath, James M Wells, Yana Zavros

Source: PLoS Pathogens, Vol 15, Iss 1, p e1007468 (2019)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/0ccabb3aad4a496e83ca473aeab518db

Establishment of Human Epithelial Enteroids and Colonoids from Whole Tissue and Biopsy

Authors: Maxime M. Mahe, author¹, Nambirajan Sundaram, author¹, Carey L. Watson, author¹, Noah F. Shroyer, author², Michael A. Helmrath, author¹

Source: Journal of Visualized Experiments. (97)

Availability: http://www.jove.com/video/52483

CSF-1 activates MAPK-dependent and p53-independent pathways to induce growth arrest of hormone-dependent human breast cancer cells.

Authors: Lee, Angel Wai-mun, Nambirajan, Sundaram, Moffat, John G

Source: Oncogene. 12/9/99, Vol. 18 Issue 52, p7477. 18p.

Subject Terms: *BREAST cancer, *CANCER cells, *CELL lines, *PROTEIN kinases

Association of Lyn tyrosine kinase with the nuclear matrix and cell-cycle-dependent changes in matrix-associated tyrosine kinase activity.

Authors: Radha, Vegesna¹, Nambirajan, Sundaram¹, Swarup, Ghanshyam¹

Source: European Journal of Biochemistry. 3/1/96, Vol. 236 Issue 2, p352-359. 8p.

Subject Terms: *PROTEIN-tyrosine kinases, *PEPTIDES, *NUCLEAR matrix, *CELL cycle, *PHOSPHORYLATION, *CELL proliferation

PTP-S2, a nuclear tyrosine phosphatase, is phosphorylated and excluded from condensed chromosomes during mitosis

Authors: Nambirajan, Sundaram, Radha, Vegesna, Kamatkar, Shubhangi, Swarup, Ghanshyam

Source: Journal of Biosciences; March 2000, Vol. 25 Issue: 1 p33-40, 8p

Enhanced expression of a chromatin associated protein tyrosine phosphatase during G0to S transition

Authors: Nambirajan, Sundaram, Sreek, R., Reddy, Antha, Swarup, Ghanshyam

Source: Journal of Biosciences; September 1995, Vol. 20 Issue: 4 p461-471, 11p

Overexpression of a nuclear protein tyrosine phosphatase increases cell proliferation

Authors: Radha, Vegesna, Nambirajan, Sundaram, Swarup, Ghanshyam

Source: FEBS Letters; June 1997, Vol. 409 Issue: 1 p33-36, 4p