Heavy water toxicity via isotope effects: Stronger than high-dose radiation, neutralized by light water.

Authors: Yasuda, Takeshi, Nakajima, Nakako Izumi, Yanaka, Tomoko, Gotoh, Takaya, Tajima, Katsushi

Source: PLoS Water; 1/29/2025, Vol. 4 Issue 1, p1-19, 19p

Subject Terms: DEUTERIUM oxide, CELL death, DNA repair, HYDROLYSIS, ATOMIC weights

Dose‐dependent effects of histone methyltransferase NSD2 on site‐specific double‐strand break repair.

Authors: Iwasaki, Koh, Tojo, Akari, Kobayashi, Haruka, Shimizu, Kai, Kamimura, Yoshitaka, Horikoshi, Yasunori, Fukuto, Atsuhiko, Sun, Jiying, Yasui, Manabu, Honma, Masamitsu, Okabe, Atsushi, Fujiki, Ryoji, Nakajima, Nakako Izumi, Kaneda, Atsushi, Tashiro, Satoshi, Sassa, Akira, Ura, Kiyoe

Source: Genes to Cells; Nov2024, Vol. 29 Issue 11, p951-965, 15p

Subject Terms: HOMOLOGOUS recombination, HISTONE methylation, GENETIC transcription, METHYLTRANSFERASES, THYMIDINE, DNA repair, DOUBLE-strand DNA breaks

RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells

Authors: Nakajima, Nakako Izumi ^*, Yamauchi, Motohiro, Kakoti, Sangeeta, Cuihua, Liu, Kato, Reona, Permata, Tiara Bunga Mayang, Iijima, Moito, Yajima, Hirohiko, Yasuhara, Takaaki, Yamada, Shigeru, Hasegawa, Sumitaka, Shibata, Atsushi ^**

Source: In DNA Repair July-August 2020 91-92

Low- and High-LET Ionizing Radiation Induces Delayed Homologous Recombination that Persists for Two Weeks before Resolving

Authors: Allen, Christopher P., Hirakawa, Hirokazu, Nakajima, Nakako Izumi, Moore, Sophia, Nie, Jingyi, Sharma, Neelam, Sugiura, Mayumi, Hoki, Yuko, Araki, Ryoko, Abe, Masumi, Okayasu, Ryuichi, Fujimori, Akira, Nickoloff, Jac A.

Source: Radiation Research, 2017 Jul 01. 188(1), 82-93.

Access URL: https://www.jstor.org/stable/26428253

Targeted cancer cell ablation in mice by an α-particle-emitting astatine-211-labeled antibody against major histocompatibility complex class I chain-related protein A and B

Authors: Li, Huizi Keiko, Hasegawa, Sumitaka, Nakajima, Nakako Izumi, Morokoshi, Yukie, Minegishi, Katsuyuki, Nagatsu, Kotaro

Source: Biochemical and biophysical research communications. 506(4):1078-1084

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100074896857.0x000001&indx=1&recIds=ETOCvdc_100074896857.0x000001

The complexity of DNA double strand breaks is a critical factor enhancing end-resection

Authors: Yajima, Hirohiko, Fujisawa, Hiroshi, Nakajima, Nakako Izumi, Hirakawa, Hirokazu, Jeggo, Penelope A., Okayasu, Ryuichi, Fujimori, Akira

Source: In DNA Repair November 2013 12(11):936-946

Selective Enhancing Effect of Early Mitotic Inhibitor 1 (Emi1) Depletion on the Sensitivity of Doxorubicin or X-ray Treatment in Human Cancer Cells

Authors: Shimizu, Natsumi, Nakajima, Nakako Izumi, Tsunematsu, Takaaki, Ogawa, Ikuko, Kawai, Hidehiko, Hirayama, Ryoichi, Fujimori, Akira, Yamada, Akiko ^**, Okayasu, Ryuichi, Ishimaru, Naozumi ^**, Takata, Takashi, Kudo, Yasusei ^**

Source: In Journal of Biological Chemistry 14 June 2013 288(24):17238-17252

Pre-Exposure to Ionizing Radiation Stimulates DNA Double Strand Break End Resection, Promoting the Use of Homologous Recombination Repair.

Authors: Nakajima, Nakako Izumi¹, Hagiwara, Yoshihiko², Oike, Takahiro³, Okayasu, Ryuichi¹, Murakami, Takeshi¹, Nakano, Takashi³, Shibata, Atsushi² shibata.at@gunma-u.ac.jp

Source: PLoS ONE. Mar2015, Vol. 10 Issue 3, p1-15. 15p.

Subject Terms: *IONIZING radiation, *DNA repair, *GENETIC recombination, *REPLICATION protein A, *PHOSPHORYLATION, *BIOMARKERS

Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites.

Authors: Yasuda, Takeshi¹, yasuda.takeshi@qst.go.jp, Kagawa, Wataru², Ogi, Tomoo³, Kato, Takamitsu A.⁴, Suzuki, Takehiro⁵, Dohmae, Naoshi⁵, Takizawa, Kazuya¹, Nakazawa, Yuka^3,6, Genet, Matthew D.⁴, Saotome, Mika², Hama, Michio⁷, Konishi, Teruaki⁷, Nakajima, Nakako Izumi⁸, Hazawa, Masaharu^1,9, Tomita, Masanori¹⁰, Koike, Manabu¹¹, Noshiro, Katsuko¹, Tomiyama, Kenichi¹, Obara, Chizuka¹, Gotoh, Takaya¹

Source: PLoS Genetics; 3/28/2018, Vol. 14 Issue 3, p1-38, 38p

Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage.

Authors: Nakajima, Nakako Izumi¹, Brunton, Holly², Watanabe, Ritsuko³, Shrikhande, Amruta² as303@sussex.ac.uk, Hirayama, Ryoichi¹, Matsufuji, Naruhiro¹, Fujimori, Akira¹, Murakami, Takeshi¹, Okayasu, Ryuichi¹, Jeggo, Penny² p.a.jeggo@sussex.ac.uk, Shibata, Atsushi²

Source: PLoS ONE. Aug2013, Vol. 8 Issue 8, p1-14. 14p.

Subject Terms: *HEAVY ions, *IRRADIATION, *IONIZATION (Atomic physics), *PARTICLE tracks (Nuclear physics), *DECONVOLUTION (Mathematics), *DIAGNOSTIC imaging, *MEDICAL radiography

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