Unraveling the role of neutrophil extracellular traps in rheumatoid arthritis: From triggers to therapeutic targets

Authors: Carmona-Rivera, Carmelo, Nakabo, Shuichiro, Kaplan, Mariana J. ^⁎

Source: In Seminars in Arthritis and Rheumatism February 2025 70 Supplement

Modulation of the Itaconate Pathway Attenuates Murine Lupus

Authors: Blanco, Luz P., Patino‐Martinez, Eduardo, Nakabo, Shuichiro, Zhang, Mingzeng, Pedersen, Hege L., Wang, Xinghao, Carmona‐Rivera, Carmelo, Claybaugh, Dillon, Yu, Zu‐Xi, Desta, Equar, Kaplan, Mariana J.

Source: Arthritis & rheumatology. 74(12):1971-1983

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196419917.0x000001&indx=1&recIds=ETOCvdc_100196419917.0x000001

Quantification of Neutrophils Undergoing NET Formation and Distinguishing Mechanisms of Neutrophil Cell Death by Use of a High-Throughput Method

Authors: Nakabo, Shuichiro, Kaplan, Mariana J., Gupta, Sarthak

Source: Methods in molecular biology. 2543:129-140

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630138602&indx=1&recIds=ETOCRN630138602

Neutrophils as Drivers of Immune Dysregulation in Autoimmune Diseases with Skin Manifestations

Authors: Nakabo, Shuichiro, Romo-Tena, Jorge, Kaplan, Mariana J.

Source: Journal of investigative dermatology. 142(PB):823-833

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155841005.0x000001&indx=1&recIds=ETOCvdc_100155841005.0x000001

Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism

Authors: Gupta, Sarthak, Nakabo, Shuichiro, Blanco, Luz P., O’Neil, Liam J., Wigerblad, Gustaf, Goel, Rishi R., Mistry, Pragnesh, Jiang, Kan, Carmona-Rivera, Carmelo, Chan, Diana W., Wang, Xinghao, Pedersen, Hege L., Gadkari, Manasi, Howe, Katherine N., Naz, Faiza, Dell’Orso, Stefania, Hasni, Sarfaraz A., Dempsey, Caeden, Buscetta, Ashley, Frischmeyer-Guerrerio, Pamela A., Kruszka, Paul, Muenke, Maximilian, Franco, Luis M., Sun, Hong-Wei, Kaplan, Mariana J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jul . 117(28), 16481-16491.

Access URL: https://www.jstor.org/stable/26935242

Severe joint deformity and patient global assessment of disease are associated with discrepancies between sonographic and clinical remission: A cross-sectional study of rheumatoid arthritis patients

Authors: Nakabo, Shuichiro, Tsuji, Yuko, Inagaki, Maiko, Tsuji, Hideaki, Nakajima, Toshiki, Murakami, Kosaku, Terao, Chikashi, Hashimoto, Motomu, Furu, Moritoshi, Tanaka, Masao, Ito, Hiromu, Fujii, Takao, Mimori, Tsuneyo, Fujii, Yasutomo

Source: Modern rheumatology. 31(2):334-342

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115641295.0x000001&indx=1&recIds=ETOCvdc_100115641295.0x000001

The circadian clock gene BMAL1 modulates autoimmunity features in lupus.

Authors: Nakabo, Shuichiro, Sandoval-Heglund, Donavon, Hanata, Norio, Brooks, Stephen, Hoffmann, Victoria, Zhang, Mingzeng, Ambler, William, Manna, Zerai, Poncio, Elaine, Hasni, Sarfaraz, Islam, Shamima, Dell'Orso, Stefania, Kaplan, Mariana J.

Source: Frontiers in Immunology; 2024, p1-15, 15p

Subject Terms: ARYL hydrocarbon receptors, CLOCK genes, SYSTEMIC lupus erythematosus, IMMUNE complexes, BONE marrow

Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus

Authors: Goel, Rishi R., Wang, Xinghao, O’Neila, Liam J., Nakabo, Shuichiro, Hasneen, Kowser, Gupta, Sarthak, Wigerblad, Gustaf, Blanco, Luz P., Kopp, Jeffrey B., Morasso, Maria I., Kotenko, Sergei V., Yu, Zu-Xi, Carmona-Rivera, Carmelo, Kaplan, Mariana J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Mar 01. 117(10), 5409-5419.

Access URL: https://www.jstor.org/stable/26929254

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

Authors: Mistry, Pragnesh, Nakabo, Shuichiro, O’Neil, Liam, Goel, Rishi R., Jiang, Kan, Carmona-Rivera, Carmelo, Gupta, Sarthak, Chan, Diana W., Carlucci, Philip M., Wang, Xinghao, Naz, Faiza, Manna, Zerai, Dey, Amit, Mehta, Nehal N., Hasni, Sarfaraz, Dell’Orso, Stefania, Gutierrez-Cruz, Gustavo, Sun, Hong-Wei, Kaplan, Mariana J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Dec 01. 116(50), 25222-25228.

Access URL: https://www.jstor.org/stable/26862043

Effects of Gasdermin D in Modulating Murine Lupus and its Associated Organ Damage

Authors: Wang, Xinghao, Blanco, Luz P., Carmona‐Rivera, Carmelo, Nakabo, Shuichiro, Pedersen, Hege L., Yu, Zu‐Xi, Kaplan, Mariana J.

Source: Arthritis & rheumatology. 72(12):2118-2129

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110333109.0x000001&indx=1&recIds=ETOCvdc_100110333109.0x000001

Feasibility of patient-oriented ultrasound joint selection: Cross-sectional observational study on rheumatoid arthritis

Authors: Kawahara, Rie, Nakabo, Shuichiro, Shimizu, Madoka, Yamamoto, Hiroko, Sasai, Tsuneo, Nishida, Yuri, Funakoshi, Sohei, Gon, Yoshie, Taniguchi, Masashi, Nakajima, Toshiki, Hiwa, Ryosuke, Hashimoto, Motomu, Tomizawa, Takuya, Azukizawa, Masayuki, Nishitani, Kohei, Murata, Koichi, Tanaka, Masao, Ito, Hiromu, Mimori, Tsuneyo, Fujii, Yasutomo

Source: Modern rheumatology. 30(6):975-981

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110734513.0x000001&indx=1&recIds=ETOCvdc_100110734513.0x000001

Activated neutrophil carbamylates albumin via the release of myeloperoxidase and reactive oxygen species regardless of NETosis

Authors: Nakabo, Shuichiro, Ohmura, Koichiro, Akizuki, Shuji, Murakami, Kosaku, Nakashima, Ran, Hashimoto, Motomu, Yoshifuji, Hajime, Tanaka, Masao, Mimori, Tsuneyo

Source: Modern rheumatology. 30(2):345-349

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099225721.0x000001&indx=1&recIds=ETOCvdc_100099225721.0x000001

Evaluation of risk factors for atherosclerosis using carotid ultrasonography in Japanese patients with rheumatoid arthritis

Authors: Yamamoto, Hiroko, Nakajima, Toshiki, Kawahara, Rie, Nakabo, Shuichiro, Hashimoto, Motomu, Yamamoto, Wataru, Masuda, Izuru, Ito, Hiromu, Mimori, Tsuneyo, Fujii, Yasutomo

Source: International journal of rheumatic diseases. 22(7):1312-1318

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085897384.0x000001&indx=1&recIds=ETOCvdc_100085897384.0x000001

Clinical and etiological meaning of anti-carbamylated protein antibodies in rheumatoid arthritis

Authors: Nakabo, Shuichiro

Source: Immunological medicine. 41(4):147-153

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103838229.0x000001&indx=1&recIds=ETOCvdc_100103838229.0x000001

Lupus-like autoimmunity and increased interferon response in patients with STAT3-deficient hyper-IgE syndrome

Authors: Goel, Rishi R., Nakabo, Shuichiro, Dizon, Brian L.P., Urban, Amanda, Waldman, Meryl, Howard, Lillian, Darnell, Dirk, Buhaya, Munir, Carmona-Rivera, Carmelo, Hasni, Sarfaraz, Kaplan, Mariana J., Freeman, Alexandra F., Gupta, Sarthak

Source: Journal of allergy and clinical immunology. 147(2):746-749.e9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128788443.0x000001&indx=1&recIds=ETOCvdc_100128788443.0x000001

Crizotinib may be effective for rheumatoid arthritis: a case report of a rheumatoid arthritis patient with lung cancer

Authors: Nakabo, Shuichiro, Gochi, Fumiaki, Yasuhara, Yumiko, Terada, Yasuji

Source: Modern rheumatology case reports. 1(2):49-53

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107990149.0x000001&indx=1&recIds=ETOCvdc_100107990149.0x000001

Biallelic human SHARPINloss of function induces autoinflammation and immunodeficiency

Authors: Oda, Hirotsugu, Manthiram, Kalpana, Chavan, Pallavi Pimpale, Rieser, Eva, Veli, Önay, Kaya, Öykü, Rauch, Charles, Nakabo, Shuichiro, Kuehn, Hye Sun, Swart, Mariël, Wang, Yanli, Çelik, Nisa Ilgim, Molitor, Anne, Ziaee, Vahid, Movahedi, Nasim, Shahrooei, Mohammad, Parvaneh, Nima, Alipour-olyei, Nasrin, Carapito, Raphael, Xu, Qin, Preite, Silvia, Beck, David B., Chae, Jae Jin, Nehrebecky, Michele, Ombrello, Amanda K., Hoffmann, Patrycja, Romeo, Tina, Deuitch, Natalie T., Matthíasardóttir, Brynja, Mullikin, James, Komarow, Hirsh, Stoddard, Jennifer, Niemela, Julie, Dobbs, Kerry, Sweeney, Colin L., Anderton, Holly, Lawlor, Kate E., Yoshitomi, Hiroyuki, Yang, Dan, Boehm, Manfred, Davis, Jeremy, Mudd, Pamela, Randazzo, Davide, Tsai, Wanxia Li, Gadina, Massimo, Kaplan, Mariana J., Toguchida, Junya, Mayer, Christian T., Rosenzweig, Sergio D., Notarangelo, Luigi D., Iwai, Kazuhiro, Silke, John, Schwartzberg, Pamela L., Boisson, Bertrand, Casanova, Jean-Laurent, Bahram, Seiamak, Rao, Anand Prahalad, Peltzer, Nieves, Walczak, Henning, Lalaoui, Najoua, Aksentijevich, Ivona, Kastner, Daniel L.

Source: Nature Immunology; 20240101, Issue: Preprints p1-14, 14p

Long-term follow-up of patients with anti-cyclic citrullinated peptide antibody-positive connective tissue disease: a retrospective observational study including information on the HLA-DRB1 allele and citrullination dependency

Authors: Iwasaki, Takeshi, Nakabo, Shuichiro, Terao, Chikashi, Murakami, Kosaku, Nakashima, Ran, Hashimoto, Motomu, Imura, Yoshitaka, Yukawa, Naoichiro, Yoshifuji, Hajime, Miura, Yasuo, Yurugi, Kimiko, Maekawa, Taira, van Delft, Myrthe A. M., Trouw, Leendert A., Fujii, Takao, Mimori, Tsuneyo, Ohmura, Koichiro

Source: Arthritis research & therapy. 22(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177565460.0x000001&indx=1&recIds=ETOCvdc_100177565460.0x000001

Chapter 7 - Polymorphonuclear cells

Authors: Nakabo, Shuichiro, Kaplan, Mariana J.

Source: In Lahita's Systemic Lupus Erythematosus Edition: Sixth Edition. 2021:99-108

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians.

Authors: Molineros, Julio E.¹, Looger, Loren L.², Kim, Kwangwoo³, Okada, Yukinori^4,5,6, Terao, Chikashi^7,8,9,10, Sun, Celi¹, Zhou, Xu-jie^11,12, Raj, Prithvi¹³, Kochi, Yuta¹⁴, Suzuki, Akari¹⁴, Akizuki, Shuji¹⁵, Nakabo, Shuichiro¹⁵, Bang, So-Young¹⁶, Lee, Hye-Soon¹⁶, Kang, Young Mo¹⁷, Suh, Chang-Hee¹⁸, Chung, Won Tae¹⁹, Park, Yong-Beom²⁰, Choe, Jung-Yoon²¹, Shim, Seung-Cheol²²

Source: PLoS Genetics; 4/25/2019, Vol. 15 Issue 4, p1-25, 25p