Impact of endoscopic ultrasound-guided tissue acquisition on prognosis and peritoneal lavage cytology in resectable or borderline resectable pancreatic ductal adenocarcinoma

Authors: Maruo, Motonobu, Ikeura, Tsukasa, Takaori, Ayaka, Ikeda, Masatoshi, Nakamaru, Koh, Ito, Takashi, Masuda, Masataka, Mitsuyama, Toshiyuki, Nakayama, Shinji, Shimatani, Masaaki, Takaoka, Makoto, Shibata, Nobuhiro, Boku, Shogen, Yasuda, Tomoyo, Miyazaki, Hidetaka, Matsumura, Kazuki, Yamaki, So, Hashimoto, Daisuke, Satoi, Sohei, Naganuma, Makoto

Source: In Pancreatology August 2024 24(5):787-795

Impact of neoadjuvant therapy on gut microbiome in patients with resectable/borderline resectable pancreatic ductal adenocarcinoma

Authors: Takaori, Ayaka, Hashimoto, Daisuke, Ikeura, Tsukasa, Ito, Takashi, Nakamaru, Koh, Masuda, Masataka, Nakayama, Shinji, Yamaki, So, Yamamoto, Tomohisa, Fujimoto, Kosuke, Matsuo, Yoshiyuki, Akagawa, Shohei, Ishida, Mitsuaki, Yamaguchi, Kiyoshi, Imoto, Seiya, Hirota, Kiichi, Uematsu, Satoshi, Satoi, Sohei, Sekimoto, Mitsugu, Naganuma, Makoto

Source: In Pancreatology June 2023 23(4):367-376

Final Analysis of COVID-19 Patients With Inflammatory Bowel Disease in Japan (J-COSMOS): A Multicenter Registry Cohort Study

Authors: Sasaki, Makoto, Iizuka, Masahiro, Fujiya, Mikihiro, Matsumoto, Takayuki, Kinjo, Fukunori, Nakamura, Shiro, Kamata, Noriko, Iijima, Hideki, Etani, Yuri, Ueno, Fumiaki, Hiraoka, Sakiko, Kondo, Takeo, Kagaya, Takashi, Naganuma, Makoto, Kobayashi, Kiyonori, Kobayashi, Taku, Yamamoto, Shuji, Naito, Yuji, Hisamatsu, Tadakazu, Furuta, Yoki, Mitsuyama, Keichi, Hashimoto, Yu, Arai, Katsuhiro, Kato, Shingo, Iwama, Itaru, Esaki, Motohiro, Tanaka, Hiroki, Nakase, Hiroshi, Motoya, Satoshi, Maemoto, Atsuo, Ashida, Toshifumi, Nishimata, Nobuaki, Aono, Shigeaki, Andoh, Akira, Yamamoto, Hironori, Ishihara, Shunji, Shimizu, Toshiaki, Yasuharu, Maeda, Kinoshita, Kenji, Fukuda, Katuyuki, Kato, Jun, Takeuchi, Ken, Nagahori, Masakazu, Fukuzawa, Masakatsu, Saruta, Masayuki, Suzuki, Takayoshi, Itabashi, Michio, Shinozaki, Masaru, Ishihara, Soichiro, Yoshimura, Naoki, Matsuoka, Katsuyoshi, Kakuta, Yoichi, Takahashi, Kenichi, Tominaga, Keiichi, Sakemi, Ryosuke, Nanjo, Sohachi, Yoshikawa, Shusaku, Ozeki, Keiji, Fuchigami, Ayako, Katsurada, Takehiko, Watanabe, Kenji, Sakuraba, Hirotake, Hirai, Fumihito, Hisabe, Takashi, Iwase, Shigeru, Ohmiya, Naoki, Hokari, Ryota, Nakai, Katsuhiko, Ueda, Takeshi, Abukawa, Daiki, Yamamoto, Shojiro, Koganei, Kazutaka, Kunisaki, Reiko, Hokama, Akira, Hayashi, Yuki, Yokoyama, Yoshihiro, Matsuura, Minoru

Source: In Gastro Hep Advances 2023 2(8):1056-1065

First-line biologics as a treatment for ulcerative colitis: a multicenter randomized control study.

Authors: Naganuma, Makoto¹ (AUTHOR) naganuma@hirakata.kmu.ac.jp, Shiga, Hisashi² (AUTHOR), Shimoda, Masayuki³ (AUTHOR), Matsuura, Minoru⁴ (AUTHOR), Takenaka, Kento⁵ (AUTHOR), Fujii, Toshimitsu⁵ (AUTHOR), Yamamoto, Shojiro⁶ (AUTHOR), Matsubayashi, Mao⁷ (AUTHOR), Kobayashi, Taku⁸ (AUTHOR), Aoyama, Nobuo⁹ (AUTHOR), Saito, Daisuke⁴ (AUTHOR), Yokoyama, Kaoru¹⁰ (AUTHOR), Moriya, Kei¹¹ (AUTHOR), Tsuchiya, Kiichiro¹² (AUTHOR), Shibui, Shunsuke⁷ (AUTHOR), Kawamoto, Ami⁵ (AUTHOR), Shimizu, Hiromichi⁵ (AUTHOR), Okamoto, Ryuichi⁵ (AUTHOR), Sakamoto, Kazuki⁶ (AUTHOR), Yaguchi, Katsuki⁷ (AUTHOR)

Source: Journal of Gastroenterology. Apr2025, Vol. 60 Issue 4, p430-441. 12p.

Subject Terms: *ULCERATIVE colitis, *DISEASE remission, *TREATMENT effectiveness, *VEDOLIZUMAB, *INFLIXIMAB

Guidelines for endoscopic diagnosis and treatment of inflammatory bowel diseases.

Authors: Matsumoto, Takayuki, Hisamatsu, Tadakazu, Esaki, Motohiro, Omori, Teppei, Sakuraba, Hirotake, Shinzaki, Shinichiro, Sugimoto, Ken, Takenaka, Kento, Naganuma, Makoto, Bamba, Shigeki, Hisabe, Takashi, Hiraoka, Sakiko, Fujiya, Mikihiro, Matsuura, Minoru, Yanai, Shunichi, Watanabe, Kenji, Ogata, Haruhiko, Andoh, Akira, Nakase, Hiroshi, Ohtsuka, Kazuo

Source: Digestive Endoscopy; Apr2025, Vol. 37 Issue 4, p319-351, 33p

Subject Terms: INFLAMMATORY bowel diseases, ENDOSCOPY, DIAGNOSIS methods, ENDOSCOPIC gastrointestinal surgery, ULCERATIVE colitis, CROHN'S disease, GASTROINTESTINAL system, PATIENT selection

Geographic Terms: JAPAN

Behçet's disease: incidence, prevalence, and real-word data on the use of biologic agents in Japan.

Authors: Hisamatsu, Tadakazu¹ (AUTHOR) thisamatsu@ks.kyorin-u.ac.jp, Naganuma, Makoto² (AUTHOR) naganuma@hirakata.kmu.ac.jp, Pinton, Philippe³ (AUTHOR) philippe.pinton@ferring.com, Takeno, Mitsuhiro⁴ (AUTHOR) m-takeno@nms.ac.jp

Source: Journal of Gastroenterology. Mar2025, Vol. 60 Issue 3, p294-305. 12p.

Subject Terms: *BEHCET'S disease, *TUMOR necrosis factors, *AUTOINFLAMMATORY diseases, *DISEASE management, *BIOLOGICALS

Geographic Terms: JAPAN

Efficacy of Dose Escalation of Oral 5-Aminosalicylic Acid for Ulcerative Colitis With a Mayo Endoscopic Subscore of 1: An Open Label Randomized Controlled Trial.

Authors: Fukuda, Tomohiro, Aoki, Yasuhiro, Kiyohara, Hiroki, Yokoyama, Ayumi, Nakazawa, Atsushi, Yoshimatsu, Yusuke, Sugimoto, Shinya, Nanki, Kosaku, Mikami, Yohei, Fukuhara, Kayoko, Mizuno, Shinta, Sujino, Tomohisa, Mutaguchi, Makoto, Takabayashi, Kaoru, Morohoshi, Yuichi, Hosoda, Yasuo, Ogata, Haruhiko, Iwao, Yasushi, Naganuma, Makoto, Kanai, Takanori

Source: Inflammatory Bowel Diseases; Mar2025, Vol. 31 Issue 3, p716-724, 9p

Clinical characteristics of immunoglobulin IgG4-related sclerosing cholangitis: Comparison of cases with and without autoimmune pancreatitis in a large cohort

Authors: Furumatsu, Keisuke, Sawai, Shigeaki, Goto, Takuma, Okumura, Toshikatsu, Suzuki, Daisuke, Otsuka, Masayuki, Kobori, Ikuhiro, Tamano, Masaya, Koizumi, Mitsuhito, Hiasa, Yoichi, Kawabe, Naoto, Hirooka, Yoshiki, Yamamoto, Satoshi, Asano, Yukio, Inui, Kazuo, Horiguchi, Akihiko, Watanabe, Hiroyuki, Toya, Daishu, Hatayama, Katsuko, Ueki, Toshiharu, Kinoshita, Norikatsu, Sugimoto, Mitsuru, Ohira, Hiromasa, Mukai, Tsuyoshi, Tomita, Eiichi, Iwata, Keisuke, Shimizu, Shogo, Suetsugu, Jun, Shimizu, Masahito, Tsuji, Keiji, Ishida, Ryoko, Ito, Masanori, Furukawa, Ryutaro, Sakamoto, Naoya, Araki, Masahiro, Tanno, Satoshi, Sakamoto, Yasunari, Ito, Tetsuhide, Takai, Satoshi, Ikeya, Shinichi, Yamada, Takanori, Kudara, Norihiko, Shimizu, Akinori, Hanada, Keiji, Ichiki, Yasunori, Kitada, Hideki, Hifumi, Michio, Kimura, Hiroyuki, Kurosaki, Masayuki, Izumi, Namiki, Sumi, Hajime, Haruta, Jun-ichi, Hayashi, Katsumi, Harada, Ryo, Inoue, Masafumi, Nakamura, Shinichiro, Ito, Tetsuya, Tomishima, Ko, Isayama, Hiroyuki, Oura, Kyoko, Masaki, Tsutomu, Shimokawahara, Naoto, Tanoue, Shirou, Maemura, Kousei, Ido, Akio, Mizushima, Ichiro, Kawano, Mitsuhiro, Yoshida, Katsunori, Naganuma, Makoto, Murata, Miki, Nishio, Akiyoshi, Fujita, Yuji, Teratani, Takuma, Matsubara, Shohei, Tamai, Hironao, Yoshida, Yuu, Azemoto, Ryousaku, Kamata, Ken, Watanabe, Tomohiro, Kurosu, Takahiro, Koizumi, Wasaburou, Fujita, Jun, Seki, Hideyuki, Ueda, Yasuhiro, Fukumoto, Takumi, Kousaki, Takuhiro, Uchida, Kazushige, Ochiai, Toshimasa, Kawasaki, Takeshi, Tanaka, Motohiko, Ishida, Etsuji, Notohara, Kenji, Mori, Hideaki, Mori, Toshiyuki, Kawabata, Hideaki, Miyata, Masatoshi, Sakagami, Junichi, Itoh, Yoshito, Shiokawa, Masahiro, Seno, Hiroshi, Watanabe, Noriko, Naitoh, Itaru, Kataoka, Hiromi, Aoki, Toshinori, Fujishiro, Mitsuhiro, Niihara, Toru, Nishimata, Hiroto, Mitoro, Akira, Yoshiji, Hitoshi, Yoshida, Motoyuki, Ikeda, Masafumi, Tomita, Kengo, Hokari, Ryota, Hayasaka, Kenji, Amano, Yuji, Shioji, Kazuhiko, Hayashi, Kazunao, Terai, Shuji, Nakajima, Michiko, Yamahana, Junya, Matsumoto, Ryusuke, Kikuchi, Hideaki, Kanamori, Akira, Kiriyama, Seiki, Iwatsu, Shinichi, Kato, Yuji, Horiguchi, Shigeru, Yagi, Takahito, Okada, Hiroyuki, Ohkawa, Kazuyoshi, Hirao, Motohiro, Hiramatsu, Naoki, Oza, Noriko, Imamura, Haruo, Baba, Takeshi, Nakano, Shigeru, Shinobi, Tetsuya, Ryozawa, Shomei, Motoya, Masayo, Nakase, Hiroshi, Kinoshita, Noboru, Ito, Kei, Miyake, Tatsuya, Kohge, Naruaki, Tobita, Hiroshi, Joshita, Satoru, Umemura, Takeji, Kawaguchi, Shinya, Ohno, Kazuya, Sonobe, Koichi, Satoh, Akihiko, Shimosegawa, Tooru, Miura, Fumihiko, Yagi, Minami, Sano, Keiji, Tanaka, Atsushi, Kin, Toshifumi, Katanuma, Akio, Koike, Kazuhiko, Miura, Shin, Masamune, Atsushi, Kawashima, Youhei, Kagawa, Tatehiro, Azuma, Seishin, Watanabe, Mamoru, Honjyo, Mitsuyoshi, Itoi, Takao, Honda, Akira, Kobayashi, Katsumasa, Asano, Toru, Kamisawa, Terumi, Mizuno, Suguru, Nishino, Takayoshi, Taniguchi, Hideaki, Tajiri, Kazuto, Yasuda, Ichiro, Tanaka, Yoshiya, Oe, Shinji, Harada, Masaru, Kurata, Masanao, Fukasawa, Mituharu, Enomoto, Nobuyuki, Kawaji, Yuki, Kitano, Masayuki, Nishise, Yuko, Hirakawa, Hidetoshi, Ishizawa, Tetsuya, Ueno, Yoshiyuki, Kaino, Miyuki, Fujimoto, Yuko, Sakaida, Isao, Kubota, Kensuke, Nakazawa, Takahiro, Takikawa, Hajime, Unno, Michiaki, Kawa, Shigeyuki, Nakamura, Seiji, Okazaki, Kazuichi

Source: In Digestive and Liver Disease October 2021 53(10):1308-1314

Serum free light chain assessment in type 1 autoimmune pancreatitis

Authors: Ikemune, Manami, Uchida, Kazushige, Tsukuda, Satoshi, Ito, Takashi, Nakamaru, Koh, Tomiyama, Takashi, Ikeura, Tsukasa, Naganuma, Makoto, Okazaki, Kazuichi

Source: In Pancreatology April 2021 21(3):658-665

The Utility of the Colectomy Risk Score in Terms of Predicting Postoperative Complications in Patients with Ulcerative Colitis

Authors: Ikebata, Akiyoshi, Okabayashi, Koji, Tsuruta, Masashi, Shigeta, Kohei, Seishima, Ryo, Naganuma, Makoto, Kitagawa, Yuko

Source: In Journal of Gastrointestinal Surgery February 2021 25(2):526-529

Effectiveness and outcomes of endoscopic resection for superficial pharyngeal squamous cell carcinomas.

Authors: Nakamura, Naohiro, Sakagami, Tomofumi, Shimizu, Minaki, Suzuki, Kensuke, Fujisawa, Takuo, Shijimaya, Takuya, Kobayashi, Sanshiro, Takahashi, Yu, Tahara, Tomomitsu, Noda, Yuri, Tsuta, Koji, Naganuma, Makoto

Source: Head & Neck; Feb2025, Vol. 47 Issue 2, p463-471, 9p

Subject Terms: SQUAMOUS cell carcinoma, ENDOSCOPIC surgery, LYMPHATIC metastasis, OVERALL survival, SURVIVAL rate

Assessment of IL-6 Pathway Inhibition in Gastrointestinal Behçet's Disease from Immunological and Clinical Perspectives.

Authors: Naganuma, Makoto, Takeno, Mitsuhiro, Çelik, Aykut Ferhat, Moots, Robert, Pinton, Philippe, Hisamatsu, Tadakazu

Source: Biomedicines; Jan2025, Vol. 13 Issue 1, p247, 19p

Subject Terms: BEHCET'S disease, TUMOR necrosis factors, INFLAMMATORY bowel diseases, DRUG development, INTESTINAL perforation

Distinct microbiome dysbiosis and epigenetic anomaly in esophageal adenocarcinoma and its underlying Barrett's esophagus.

Authors: Shijimaya, Takuya, Tahara, Tomomitsu, Yamazaki, Jumpei, Kobayashi, Sanshiro, Matsumoto, Yasushi, Nakamura, Naohiro, Takahashi, Yu, Tomiyama, Takashi, Fukui, Toshiro, Shibata, Tomoyuki, Naganuma, Makoto

Source: Clinical Epigenetics; 12/19/2024, Vol. 16 Issue 1, p1-11, 11p

Significance of Conducting 2 Types of Fecal Tests in Patients With Ulcerative Colitis

Authors: Naganuma, Makoto, Kobayashi, Taku, Nasuno, Masanao, Motoya, Satoshi, Kato, Shingo, Matsuoka, Katsuyoshi, Hokari, Ryota, Watanabe, Chikako, Sakamoto, Hirotsugu, Yamamoto, Hironori, Sasaki, Makoto, Watanabe, Kenji, Iijima, Hideki, Endo, Yutaka, Ichikawa, Hitoshi, Ozeki, Keiji, Tanida, Satoshi, Ueno, Nobuhiro, Fujiya, Mikihiro, Sako, Minako, Takeuchi, Ken, Sugimoto, Shinya, Abe, Takayuki, Hibi, Toshifumi, Suzuki, Yasuo, Kanai, Takanori

Source: In Clinical Gastroenterology and Hepatology May 2020 18(5):1102-1111

Difference in the clinical characteristic and prognosis of colitis-associated cancer and sporadic neoplasia in ulcerative colitis patients

Authors: Mutaguchi, Makoto, Naganuma, Makoto, Sugimoto, Shinya, Fukuda, Tomohiro, Nanki, Kosaku, Mizuno, Shinta, Hosoe, Naoki, Shimoda, Masayuki, Ogata, Haruhiko, Iwao, Yasushi, Kanai, Takanori

Source: In Digestive and Liver Disease September 2019 51(9):1257-1264

Platelet activation through CD62P and the formation of platelet–monocyte complexes are associated with the exacerbation of mucosal inflammation in patients with ulcerative colitis.

Authors: Sano, Yasuki, Tomiyama, Takashi, Yagi, Naoto, Ito, Yuka, Honzawa, Yusuke, Tahara, Tomomitsu, Ikeura, Tsukasa, Fukui, Toshiro, Shimoda, Shinji, Naganuma, Makoto

Source: Scientific Reports; 11/14/2024, Vol. 12 Issue 1, p1-10, 10p

Impact of twice‐daily budesonide foam administration on early clinical response and endoscopic remission in patients with ulcerative colitis: a post hoc analysis.

Authors: Watanabe, Kenji, Hirai, Fumihito, Kobayashi, Kiyonori, Takeuchi, Ken, Kurosu, Shinsuke, Inagaki, Katsutoshi, Iwayama, Ken‐ichi, Naganuma, Makoto

Source: Journal of Gastroenterology & Hepatology; Nov2024, Vol. 39 Issue 11, p2367-2376, 10p

Subject Terms: CLINICAL trials, ULCERATIVE colitis, TREATMENT effectiveness, BUDESONIDE, PROGNOSIS

Gastric microbiome composition accompanied with the Helicobacter pylori related DNA methylation anomaly.

Authors: Shijimaya, Takuya, Tahara, Tomomitsu, Shimogama, Tsubasa, Yamazaki, Jumpei, Kobayashi, Sanshiro, Nakamura, Naohiro, Takahashi, Yu, Tomiyama, Takashi, Fukui, Toshiro, Naganuma, Makoto

Source: Epigenomics; 2024, Vol. 16 Issue 21/22, p1329-1336, 8p

A method of "Noninjecting Resection using Bipolar Soft coagulation mode; NIRBS" for superficial non-ampullary duodenal epithelial tumor: a pilot study.

Authors: Tokuhara, Mitsuo, Sano, Yasushi, Watanabe, Yoshifumi, Nakata, Hidetoshi, Nakahira, Hiroko, Furukawa, Shingo, Ohtsu, Takuya, Nakamura, Naohiro, Ito, Takashi, Torii, Ikuko, Yamashina, Takeshi, Shimatani, Masaaki, Naganuma, Makoto

Source: BMC Gastroenterology; 10/1/2024, Vol. 24 Issue 1, p1-7, 7p

Subject Terms: EPITHELIAL tumors, ENDOSCOPIC surgery, BLOOD coagulation, COAGULATION, PILOT projects

Toll-Like Receptor 7 Agonist–Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells

Authors: Kiyohara, Hiroki, Sujino, Tomohisa, Teratani, Toshiaki, Miyamoto, Kentaro, Arai, Mari Mochizuki, Nomura, Ena, Harada, Yosuke, Aoki, Ryo, Koda, Yuzo, Mikami, Yohei, Mizuno, Shinta, Naganuma, Makoto, Hisamatsu, Tadakazu, Kanai, Takanori

Source: In Cellular and Molecular Gastroenterology and Hepatology 2019 7(1):135-156