Recent advances in fluorine chemistry using flow technology

Authors: Muta, Kensuke, Soutome, Hiroki, Nagaki, Aiichiro

Source: In Journal of Fluorine Chemistry October 2024 279

Continuous enantiomeric separation using water-oil-water segmented flow system

Authors: Muranaka, Yosuke, Maki, Taisuke, Nakayoshi, Daiki, Asano, Shusaku, Ikebata, Katsuya, Nagaki, Aiichiro, Ashikari, Yosuke, Mandai, Kyoko, Mae, Kazuhiro

Source: In Chemical Engineering Journal 1 August 2023 469

Rapid access to organic triflates based on flash generation of unstable sulfonium triflates in flowElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2cc02344j

Authors: Takumi, Masahiro, Sakaue, Hodaka, Shibasaki, Daiki, Nagaki, Aiichiro

Source: Chemical communications. 58(60):8344-8347

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156233289.0x000001&indx=1&recIds=ETOCvdc_100156233289.0x000001

Flow grams-per-hour production enabled by hierarchical bimodal porous silica gel supported palladium column reactor having low pressure drop

Authors: Ashikari, Yosuke, Maekawa, Kei, Takumi, Masahiro, Tomiyasu, Noriyuki, Fujita, Chiemi, Matsuyama, Kiyoshi, Miyamoto, Riichi, Bai, Hongzhi, Nagaki, Aiichiro

Source: Catalysis today. 388:231-236

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155962578.0x000001&indx=1&recIds=ETOCvdc_100155962578.0x000001

Continuous flow synthesis of cyclobutenes via lithium ynolates.

Authors: Kohyama, Aki, Namioka, Motoki, Naka, Hiroshi, Ashikari, Yosuke, Nagaki, Aiichiro, Takikawa, Hiroshi, Yamaoka, Yousuke, Takasu, Kiyosei

Source: Green Chemistry; 3/14/2025, Vol. 27 Issue 10, p2760-2765, 6p

Subject Terms: RING formation (Chemistry), CHEMICAL species, RAMAN spectroscopy, CYCLOBUTENES, ENOLATES

Sequence‐Defined Synthesis Enabled by Fast and Living Anionic Monoaddition of Vinyl Monomers.

Authors: Okamoto, Kazuhiro¹, Yoo, Dong‐eun¹, Yoshioka, Rikako¹, Nakasato, Ryohei¹, Ashikari, Yosuke¹, Kitayama, Kenji¹, Nagaki, Aiichiro¹, nagaki@sci.hokudai.ac.jp

Source: Angewandte Chemie; 1/21/2025, Vol. 137 Issue 4, p1-8, 8p

Defluorinative functionalization approach led by difluoromethyl anion chemistry.

Authors: Muta, Kensuke, Okamoto, Kazuhiro, Nakayama, Hiroki, Wada, Shuto, Nagaki, Aiichiro

Source: Nature Communications; 1/7/2025, Vol. 16 Issue 1, p1-9, 9p

Subject Terms: FLUOROALKYL compounds, ORGANOFLUORINE compounds, FUNCTIONAL groups, TRANSFORMATION groups, ANIONS

Stille, Heck, and Sonogashira coupling and hydrogenation catalyzed by porous-silica-gel-supported palladium in batch and flow

Authors: Ashikari Yosuke, Maekawa Kei, Ishibashi Mai, Fujita Chiemi, Shiosaki Kiyonari, Bai Hongzhi, Matsuyama Kiyoshi, Nagaki Aiichiro

Source: Green Processing and Synthesis, Vol 10, Iss 1, Pp 722-728 (2021)

Subject Terms: heterogeneous catalyst, flow reaction, stille coupling, hydrogenation, Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2191-9550

Access URL: https://doaj.org/article/58d8f6f4d50e4c9391de25cb58874bad

Switchable Chemoselectivity of Reactive Intermediates Formation and Their Direct Use in A Flow Microreactor

Authors: Ashikari, Yosuke, Tamaki, Takashi, Kawaguchi, Tomoko, Furusawa, Mai, Yonekura, Yuya, Ishikawa, Susumu, Takahashi, Yusuke, Aizawa, Yoko, Nagaki, Aiichiro

Source: Chemistry. 27(65):16107-16111

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135568579.0x000001&indx=1&recIds=ETOCvdc_100135568579.0x000001

Insight into the Ferrier Rearrangement by Combining Flash Chemistry and Superacids

Authors: Bhuma, Naresh, Lebedel, Ludivine, Yamashita, Hiroki, Shimizu, Yutaka, Abada, Zahra, Ardá, Ana, Désiré, Jérôme, Michelet, Bastien, Martin‐Mingot, Agnès, Abou‐Hassan, Ali, Takumi, Masahiro, Marrot, Jérôme, Jiménez‐Barbero, Jesús, Nagaki, Aiichiro, Blériot, Yves, Thibaudeau, Sébastien

Source: Angewandte Chemie international edition. 60(4):2036-2041

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100124253103.0x000001&indx=1&recIds=ETOCvdc_100124253103.0x000001

Homogeneous Catalyzed Aryl–Aryl Cross-Couplings in Flow

Authors: Ashikari, Yosuke, Nagaki, Aiichiro

Source: Synthesis. 53(11):1879-1888

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189226966.0x000001&indx=1&recIds=ETOCvdc_100189226966.0x000001

Reaction Selectivity Control in Flash Synthetic Chemistry

Authors: Tamaki, Takashi, Nagaki, Aiichiro

Source: Yūki Gōsei Kagaku Kyōkaishi. 79(5):483-491

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626526273&indx=1&recIds=ETOCRN626526273

External Flash Generation of Carbenoids Enables Monodeuteration of Dihalomethanes

Authors: Okamoto, Kazuhiro, Higuma, Ryosuke, Muta, Kensuke, Fukumoto, Keita, Tsuchihashi, Yuta, Ashikari, Yosuke, Nagaki, Aiichiro

Source: Chemistry. 29(47)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190833402.0x000001&indx=1&recIds=ETOCvdc_100190833402.0x000001

Cover Feature: External Flash Generation of Carbenoids Enables Monodeuteration of Dihalomethanes (Chem. Eur. J. 47/2023)

Authors: Okamoto, Kazuhiro, Higuma, Ryosuke, Muta, Kensuke, Fukumoto, Keita, Tsuchihashi, Yuta, Ashikari, Yosuke, Nagaki, Aiichiro

Source: Chemistry. 29(47)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190833492.0x000001&indx=1&recIds=ETOCvdc_100190833492.0x000001

Flow‐Chemistry‐Enabled Synthesis of 5‐Diethylboryl‐2, 3′‐bipyridine and Its Self‐Assembly Dynamics

Authors: Wakabayashi, Shigeharu, Takumi, Masahiro, Kamio, Shintaro, Wakioka, Masayuki, Ohki, Yasuhiro, Nagaki, Aiichiro

Source: Chemistry. 29(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181670371.0x000001&indx=1&recIds=ETOCvdc_100181670371.0x000001

Recent topics of functionalized organolithiums using flow microreactor chemistry

Authors: Nagaki, Aiichiro

Source: In Tetrahedron Letters 8 August 2019 60(32)

A Novel Approach to Functionalization of Aryl Azides through the Generation and Reaction of Organolithium Species Bearing Masked Azides in Flow Microreactors

Authors: Ichinari, Daisuke, Ashikari, Yosuke, Mandai, Kyoko, Aizawa, Yoko, Yoshida, Jun‐ichi, Nagaki, Aiichiro

Source: Angewandte Chemie. 132(4):1583-1587

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110414033.0x000001&indx=1&recIds=ETOCvdc_100110414033.0x000001

A Synthetic Approach to Dimetalated Arenes Using Flow Microreactors and the Switchable Application to Chemoselective Cross-Coupling Reactions

Authors: Ashikari, Yosuke, Kawaguchi, Tomoko, Mandai, Kyoko, Aizawa, Yoko, Nagaki, Aiichiro

Source: Journal of the American Chemical Society. 142(40):17039-17047

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625039123&indx=1&recIds=ETOCRN625039123

Pd catalysts supported on dual-pore monolithic silica beads for chemoselective hydrogenation under batch and flow reaction conditionsElectronic supplementary information (ESI) available. See DOI: 10.1039/d0cy01442g

Authors: Yamada, Tsuyoshi, OgawaThese authors contributed equally to this work., Aya, Masuda, Hayato, Teranishi, Wataru, Fujii, Akiko, Park, Kwihwan, Ashikari, Yosuke, Tomiyasu, Noriyuki, Ichikawa, Tomohiro, Miyamoto, Riichi, Bai, Hongzhi, Matsuyama, Kiyoshi, Nagaki, Aiichiro, Sajiki, Hironao

Source: Catalysis science & technology. 10(18):6359-6367

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108093762.0x000001&indx=1&recIds=ETOCvdc_100108093762.0x000001

Fluoro‐Substituted Methyllithium Chemistry: External Quenching Method Using Flow Microreactors

Authors: Colella, Marco, Tota, Arianna, Takahashi, Yusuke, Higuma, Ryosuke, Ishikawa, Susumu, Degennaro, Leonardo, Luisi, Renzo, Nagaki, Aiichiro

Source: Angewandte Chemie. 132(27):11016-11020

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107359582.0x000001&indx=1&recIds=ETOCvdc_100107359582.0x000001