Clinical Trial Protocol: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy, and Safety Study Comparing EG-1962 to Standard of Care Oral Nimodipine in Adults with Aneurysmal Subarachnoid Hemorrhage [NEWTON-2 (Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After SubarachNoid Hemorrhage)].

Authors: Hänggi, Daniel, Etminan, Nima, Mayer, Stephan A., Aldrich, E. Francois, Diringer, Michael N., Schmutzhard, Erich, Faleck, Herbert J., Ng, David, Saville, Benjamin R., Macdonald, R. Loch, for the NEWTON Investigators, NEWTON Investigators

Source: Neurocritical Care; Feb2019, Vol. 30 Issue 1, p88-97, 10p

Subject Terms: SUBARACHNOID hemorrhage, MONTREAL Cognitive Assessment, CEREBRAL infarction, NIMODIPINE, RESEARCH protocols

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Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]).

Authors: Hänggi, Daniel, Etminan, Nima, Aldrich, Francois, Steiger, Hans Jakob, Mayer, Stephan A., Diringer, Michael N., Hoh, Brian L., Mocco, J., Faleck, Herbert J., Macdonald, R. Loch, NEWTON Investigators

Source: Stroke (00392499); Jan2017, Vol. 48 Issue 1, p145-151, 11p, 2 Diagrams, 4 Charts, 2 Graphs

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