Neurons Co-Expressing GLP-1, CCK, and PYY Receptors Particularly in Right Nodose Ganglion and Innervating Entire GI Tract in Mice.

Authors: Lansbury, Elizabeth Laura¹ (AUTHOR), Vana, Vasiliki^1,2 (AUTHOR), Lund, Mari Lilith^1,3 (AUTHOR), Ludwig, Mette Q.^1,4 (AUTHOR), Mamedova, Esmira^2,5 (AUTHOR), Gautron, Laurent^3,6 (AUTHOR), Arnold, Myrtha^1,4 (AUTHOR), Egerod, Kristoffer Lihme^1,2 (AUTHOR), Kuhre, Rune Ehrenreich^1,3,5 (AUTHOR), Holst, Jens Juul^1,4,5 (AUTHOR), Rekling, Jens^2,5 (AUTHOR), Schwartz, Thue W.^1,6 (AUTHOR), Pankratova, Stanislava^1,6 (AUTHOR), Dmytriyeva, Oksana¹ (AUTHOR) oksana@sund.ku.dk

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 5, p2053. 23p.

Subject Terms: *NEUROPEPTIDE Y receptors, *SEROTONIN receptors, *HORMONE receptors, *ENTEROENDOCRINE cells, *GASTROINTESTINAL hormones

Heterobivalent Dual-Target Peptide for Integrin-α v β 3 and Neuropeptide Y Receptors on Breast Tumor.

Authors: Ferreira, Aryel H.^1,2,3 (AUTHOR) aryel.ferreira@mackenzie.br, Real, Caroline C.⁴ (AUTHOR), Malafaia, Osvaldo² (AUTHOR)

Source: Pharmaceuticals (14248247). Oct2024, Vol. 17 Issue 10, p1328. 13p.

Subject Terms: *NEUROPEPTIDE Y receptors, *NEUROPEPTIDE Y, *PEPTIDES, *BREAST tumors, *COMPUTED tomography, *BREAST

Molecular Determinants for Photodynamic Therapy Resistance and Improved Photosensitizer Delivery in Glioma.

Authors: Aebisher, David¹ (AUTHOR) daebisher@ur.edu.pl, Woźnicki, Paweł² (AUTHOR) pw118616@stud.ur.edu.pl, Czarnecka-Czapczyńska, Magdalena³ (AUTHOR) magdalena.czarnecka921114@gmail.com, Dynarowicz, Klaudia⁴ (AUTHOR) kdynarowicz@ur.edu.pl, Szliszka, Ewelina⁵ (AUTHOR) eszliszka@sum.edu.pl, Kawczyk-Krupka, Aleksandra³ (AUTHOR) daebisher@ur.edu.pl, Bartusik-Aebisher, Dorota⁶ (AUTHOR) dbartusik-aebisher@ur.edu.pl

Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8708. 32p.

Subject Terms: *NEUROPEPTIDE Y receptors, *VASCULAR endothelial growth factors, *HYPOXIA-inducible factor 1, *SCIENTIFIC literature, *GENETIC profile

Next-generation neuropeptide Y receptor small-molecule agonists inhibit mosquito-biting behavior.

Authors: Zeledon, Emely V.^1,2 (AUTHOR), Baxt, Leigh A.³ (AUTHOR), Khan, Tanweer A.^3,4 (AUTHOR), Michino, Mayako³ (AUTHOR), Miller, Michael³ (AUTHOR), Huggins, David J.^3,5 (AUTHOR), Jiang, Caroline S.⁶ (AUTHOR), Vosshall, Leslie B.^1,2,7 (AUTHOR), Duvall, Laura B.⁸ (AUTHOR) lbd2126@columbia.edu

Source: Parasites & Vectors. 6/28/2024, Vol. 17, p1-12. 12p.

Subject Terms: *NEUROPEPTIDE Y receptors, *AEDES aegypti, *NEUROPEPTIDES, *STRUCTURE-activity relationships, *MOSQUITOES, *VECTOR control

Enhancement of neurogenesis and cognition through intranasal co-delivery of galanin receptor 2 (GALR2) and neuropeptide Y receptor 1 (NPY1R) agonists: a potential pharmacological strategy for cognitive dysfunctions.

Authors: Sánchez-Varo, Raquel^1,2,3 (AUTHOR), López-Salas, Alexander^1,4 (AUTHOR), Beltran-Casanueva, Rasiel^4,5 (AUTHOR), Díaz-Sánchez, Estela^1,6 (AUTHOR), Alvarez-Contino, Jose Erik^1,4 (AUTHOR), Barbancho-Fernández, Miguel Angel^1,2 (AUTHOR), Serrano-Castro, Pedro^2,6,7 (AUTHOR), Fuxe, Kjell⁵ (AUTHOR), Borroto-Escuela, Dasiel O.^1,2,4,5 (AUTHOR), García-Casares, Natalia^1,2,8 (AUTHOR), Narváez, Manuel^1,2,6 (AUTHOR) mnarvaez@uma.es

Source: Behavioral & Brain Functions. 3/28/2024, Vol. 20 Issue 1, p1-12. 12p.

Subject Terms: *NEUROPEPTIDE Y receptors, *GALANIN, *COGNITION disorders, *SPATIAL memory, *NEURONAL differentiation

GLP-1R/NPY2R regulate gene expression, ovarian and adrenal morphology in HFD mice.

Authors: Khan, Dawood¹ d.khan@ulster.ac.uk, Sridhar, Ananyaa¹, Moffett, Charlotte R.¹

Source: Journal of Endocrinology. Feb2025, Vol. 264 Issue 2, p1-14. 14p.

Subject Terms: *NEUROPEPTIDE Y receptors, *GLUCAGON-like peptide-1 receptor, *CORPUS luteum, *OVARIAN follicle, *ESTRUS

Integrated Clinical Genetic Analysis Reveals Neurotransmitter Receptor Dysregulation in Meningiomas Causing Seizure.

Authors: Khan, A. Basit¹ (AUTHOR), McDonald, Malcolm F.¹ (AUTHOR), Harmanci, Akdes¹ (AUTHOR), English, Collin¹ (AUTHOR), Harmanci, Arif² (AUTHOR), Klisch, Tiemo¹ (AUTHOR), Patel, Akash J.¹ (AUTHOR)

Source: Journal of Neurological Surgery. Part B. Skull Base. 2025 Supplement 1, Vol. 86, pS1-S576. 576p.

Subject Terms: *NEUROPEPTIDE Y receptors, *EXCITATORY postsynaptic potential, *TEMPORAL lobe epilepsy, *EMERGENCY room visits, *NEUROTRANSMITTER receptors, *NEUROPEPTIDES, *GABA receptors

A randomized phase I study of BI 1820237, a novel neuropeptide Y receptor type 2 agonist, alone or in combination with low‐dose liraglutide in otherwise healthy men with overweight or obesity.

Authors: Beetz, Nadine¹ (AUTHOR), Kalsch, Brigitte² (AUTHOR), Forst, Thomas² (AUTHOR), Schmid, Bernhard¹ (AUTHOR), Schultz, Armin² (AUTHOR), Hennige, Anita M.³ (AUTHOR) anita.hennige@boehringer-ingelheim.com

Source: Diabetes, Obesity & Metabolism. Jan2025, Vol. 27 Issue 1, p71-80. 10p.

Subject Terms: *NEUROPEPTIDE Y receptors, *NEUROPEPTIDE Y, *GASTRIC emptying, *BODY mass index, *LIRAGLUTIDE

Neuro- and vasoprotective potential of neuropeptide Y Y2 receptor agonist, NPY13-36, against transient focal cerebral ischemia in spontaneously hypertensive rats.

Authors: Przykaza, Łukasz¹ (AUTHOR) lprzykaza@imdik.pan.pl, Domin, Helena² (AUTHOR), Śmiałowska, Maria² (AUTHOR), Stanaszek, Luiza³ (AUTHOR), Boguszewski, Paweł M.⁴ (AUTHOR), Kozniewska, Ewa¹ (AUTHOR) ekozniewska@imdik.pan.pl

Source: Neuroscience. Dec2024, Vol. 562, p10-23. 14p.

Subject Terms: *TRANSIENT ischemic attack, *NEUROPEPTIDE Y receptors, *NITRIC-oxide synthases, *CEREBRAL ischemia, *TETRAZOLIUM chloride

Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling.

Authors: Pascetta, Sydney A.¹ (AUTHOR), Kirsh, Sarah M.¹ (AUTHOR), Cameron, Makenna¹ (AUTHOR), Uniacke, James¹ (AUTHOR) juniacke@uoguelph.ca

Source: BMC Cancer. 6/1/2023, Vol. 23 Issue 1, p1-15. 15p.

Subject Terms: *NEUROPEPTIDE Y receptors, *G protein coupled receptors, *BREAST cancer, *NEUROPEPTIDE Y, *ESTROGEN receptors, *ESTROGEN

The longevity response to warm temperature is neurally controlled via the regulation of collagen genes.

Authors: Palani, Sankara Naynar¹ (AUTHOR), Sellegounder, Durai¹ (AUTHOR), Wibisono, Phillip¹ (AUTHOR), Liu, Yiyong^1,2 (AUTHOR) yiyong.liu@wsu.edu

Source: Aging Cell. May2023, Vol. 22 Issue 5, p1-17. 17p.

Subject Terms: *LONGEVITY, *NEUROPEPTIDE Y receptors, *CHEMICAL kinetics, *GENETIC regulation, *G protein coupled receptors, *GENE expression

Dynamic regulation of CeA gene expression during acute and protracted abstinence from chronic binge drinking of male and female C57BL/6J mice.

Authors: Méndez, Hernán G.^1,2 (AUTHOR), Neira, Sofia¹ (AUTHOR), Flanigan, Meghan E.¹ (AUTHOR), Haun, Harold L.¹ (AUTHOR), Boyt, Kristen M.¹ (AUTHOR), Thiele, Todd E.^1,3 (AUTHOR), Kash, Thomas L.^1,3,4 (AUTHOR) thomas_kash@med.unc.edu

Source: Alcohol. Nov2024, Vol. 120, p179-193. 15p.

Subject Terms: *GABA receptors, *NEUROPEPTIDE Y receptors, *CORTICOTROPIN releasing hormone, *GENETIC regulation, *G protein coupled receptors, *NEUROPEPTIDES

The effect of Neuropeptide Y Y2 receptor blockade on memory impairment and autophagy in a rat model of Alzheimer’s disease.

Authors: Esfandiari, Esfandiar¹, Hosseinkhani, Ali¹, Rashtiani, Samira², Rohampour, Kambiz², Jafari, Adele² jafari.adele@gums.ac.ir

Source: Physiology & Pharmacology. Jul2024, Vol. 28 Issue 2, p117-127. 11p.

Subject Terms: *NEUROPEPTIDE Y receptors, *RECOGNITION (Psychology), *NEUROPEPTIDE Y, *LABORATORY rats, *WESTERN immunoblotting

Attenuation of the Counter-Regulatory Glucose Response in CVLM C1 Neurons: A Possible Explanation for Anorexia of Aging.

Authors: Ramlan, Hajira¹ (AUTHOR) hajiraramlan@gmail.com, Damanhuri, Hanafi Ahmad¹ (AUTHOR) hanafi.damanhuri@ppukm.ukm.edu.my

Source: Biomolecules (2218-273X). Mar2022, Vol. 12 Issue 3, p449. 11p.

Subject Terms: *NEUROPEPTIDE Y receptors, *SPRAGUE Dawley rats, *NEURONS, *TYROSINE hydroxylase, *ANOREXIA nervosa, *BRAIN stem

NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer.

Authors: Bhat, Raksha¹ (AUTHOR), Thangavel, Hariprasad¹ (AUTHOR), Abdulkareem, Noor Mazin² (AUTHOR), Vasaikar, Suhas³ (AUTHOR), De Angelis, Carmine^3,4 (AUTHOR), Bae, Leon¹ (AUTHOR), Cataldo, Maria Letizia³ (AUTHOR), Nanda, Sarmistha³ (AUTHOR), Fu, Xiaoyong^3,5,6 (AUTHOR), Zhang, Bing^3,5,7 (AUTHOR), Schiff, Rachel^3,5,6,8 (AUTHOR), Trivedi, Meghana V.^1,2,3,5,8 (AUTHOR) mtrivedi@central.uh.edu

Source: Scientific Reports. 2/4/2022, Vol. 12 Issue 1, p1-12. 12p.

Subject Terms: *NEUROPEPTIDE Y receptors, *EPIDERMAL growth factor receptors, *G protein coupled receptors, *BREAST cancer, *HORMONE therapy

Toxic stress-specific cytoprotective responses regulate learned behavioral decisions in C. elegans.

Authors: Hajdú, Gábor¹, Gecse, Eszter¹, Taisz, István^1,2, Móra, István¹, Sőti, Csaba¹ soti.csaba@med.semmelweis-univ.hu

Source: BMC Biology. 2/9/2021, Vol. 19 Issue 1, p1-20. 20p.

Subject Terms: *CAENORHABDITIS elegans, *NEUROPEPTIDE Y receptors, *OLFACTORY receptors, *FOOD contamination, *PROTEIN kinases

Determination of neuropeptide Y Y1 receptor antagonist BIBP 3226 and evaluation of receptor expression based on liquid chromatography coupled with tandem mass spectrometry.

Authors: Barreiros, Luisa^1,2 (AUTHOR), Silva, Eduarda M. P.¹ (AUTHOR), Alencastre, Inês S.^3,4 (AUTHOR), Lamghari, Meriem^3,4,5 (AUTHOR), Segundo, Marcela A.¹ (AUTHOR) msegundo@ff.up.pt

Source: Analytical & Bioanalytical Chemistry. Sep2020, Vol. 412 Issue 24, p6625-6632. 8p.

Subject Terms: *NEUROPEPTIDE Y receptors, *TANDEM mass spectrometry, *NEUROPEPTIDE Y, *LIQUID chromatography, *BONE marrow cells, *BONE regeneration, *MICELLAR liquid chromatography, *BONE morphogenetic protein receptors

Inflammation changes the expression of neuropeptide Y receptors in the pig myometrium and their role in the uterine contractility.

Authors: Jana, Barbara¹ (AUTHOR) b.jana@pan.olsztyn.pl, Całka, Jarosław² (AUTHOR), Palus, Katarzyna² (AUTHOR)

Source: PLoS ONE. 7/10/2020, Vol. 15 Issue 7, p1-19. 19p.

Subject Terms: *NEUROPEPTIDE Y, *NEUROPEPTIDE Y receptors, *UTERINE contraction, *MYOMETRIUM, *ESTRUS, *PROTEIN expression

Exploring the Anxiolytic Potential of NPY by a Dipeptidyl Peptidase-IV Inhibitor in an Animal Model of PTSD.

Authors: Dahan, Matan, Zohar, Joseph, Todder, Doron, Mathé, Aleksander A, Cohen, Hagit

Source: International Journal of Neuropsychopharmacology; Dec2024, Vol. 27 Issue 12, p1-11, 11p

Subject Terms: NEUROPEPTIDE Y receptors, NEUROPEPTIDE Y, POST-traumatic stress disorder, ENZYME-linked immunosorbent assay, STARTLE reaction

Formation of Hemihydrate Crystal form Overcomes Milling Issue Induced by Exposed Functional Groups on Cleavage Plane for a Y5 Receptor Antagonist of Neuropeptide Y.

Authors: Nagamatsu, Daiki¹ (AUTHOR), Ando, Shigeru² (AUTHOR), Fujimura, Yuko³ (AUTHOR), Miyano, Tetsuya¹ (AUTHOR), Sugita, Katsuji¹ (AUTHOR), Ueda, Hiroshi^1,4 (AUTHOR) hiroshi.ueda@shionogi.co.jp

Source: Journal of Pharmaceutical Sciences. Sep2023, Vol. 112 Issue 9, p2516-2523. 8p.

Subject Terms: *FUNCTIONAL groups, *NEUROPEPTIDE Y receptors, *X-ray powder diffraction, *CRYSTALS, *CRYSTAL structure