EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer

Authors: Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An

Source: Journal of Experimental & Clinical Cancer Research, Vol 44, Iss 1, Pp 1-22 (2025)

Subject Terms: N-acetyltransferase 10, Colorectal cancer, Cetuximab, Remodelin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/415357e3ed7b4d6e8f7791a7b5ff9837

Compression force promotes the osteogenic differentiation of periodontal ligament stem cells by regulating NAT10-mediated ac4C modification of BMP2

Authors: Yan Feng, Ting Zhang, Yue Chang

Source: Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-11 (2024)

Subject Terms: Orthodontic treatment, Periodontal ligament stem cells, N-acetyltransferase 10, N4-acetylcytidine modification, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/14ff262c987a45c7964ad2ecff68fed7

NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA

Authors: Zhouqi Wang, Xinxing Wan, Md Asaduzzaman Khan, Lin Peng, Xiaoying Sun, Xuan Yi, Ke Chen

Source: Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-15 (2024)

Subject Terms: N-acetyltransferase 10, ac4C modification, Srebf1, Scap, Liver lipogenesis, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/1476-511X

Access URL: https://doaj.org/article/a5655918a80b440184061f7da3a0d544

Targeting N4‐acetylcytidine suppresses hepatocellular carcinoma progression by repressing eEF2‐mediated HMGB2 mRNA translation

Authors: Hailing Liu, Lei Xu, Shiwei Yue, Hongfei Su, Xing Chen, Qiumeng Liu, Hui Li, Huifang Liang, Xiaoping Chen, Jiefeng He, Zeyang Ding, Bixiang Zhang

Source: Cancer Communications, Vol 44, Iss 9, Pp 1018-1041 (2024)

Subject Terms: N4‐acetylcytidine, N‐acetyltransferase 10, hepatocellular carcinoma, mRNA translation, targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/6514adfb45334e62b419b67a385c48fb

Biological Function and Mechanism of NAT10 in Cancer

Authors: Yufeng Han, Xinxin Zhang, Lei Miao, Huiran Lin, Zhenjian Zhuo, Jing He, Wen Fu

Source: Cancer Innovation, Vol 4, Iss 1, Pp n/a-n/a (2025)

Subject Terms: acetyltransferase, cancer, N‐acetyltransferase 10, N4‐acetylcytidine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2770-9191; https://doaj.org/toc/2770-9183

Access URL: https://doaj.org/article/e8eb5aaa3d5c4980a8d07900110be29a

Inhibition of Ribosome Biogenesis In Vivo Causes p53-Dependent Death and p53-Independent DysfunctionSummary

Authors: Charles J. Cho, Thanh Nguyen, Amala K. Rougeau, Yang-Zhe Huang, Sarah To, Xiaobo Lin, Supuni Thalalla Gamage, Jordan L. Meier, Jason C. Mills

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 19, Iss 7, Pp 101496- (2025)

Subject Terms: Ribosome, N-Acetyltransferase 10, Nucleolus, p53, Paligenosis, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X25000372; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/3a48b76fcc9d4f1d8a94021484fdd1dd

The role and mechanism of NAT10‐mediated ac4C modification in tumor development and progression

Authors: Zhuoran Gu, Libin Zou, Xinjian Pan, Yang Yu, Yongqiang Liu, Zhijin Zhang, Ji Liu, Shiyu Mao, Junfeng Zhang, Changcheng Guo, Wei Li, Jiang Geng, Wentao Zhang, Xudong Yao, Bing Shen

Source: MedComm, Vol 5, Iss 12, Pp n/a-n/a (2024)

Subject Terms: cancer, epitranscriptome, N4‐acetylation (ac4C), N‐acetyltransferase 10 (NAT10), RNA modification, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/54c4a92227d242d4a14739bc3ff7c773

NAT10 drives endometriosis progression through acetylation and stabilization of TGFB1 mRNA

Authors: Liu, Na ¹, YangOu, Jing ¹, Wei, Chenxuan, Li, Guojing, Yu, Ruoer, Lin, Yu ^⁎⁎, Xu, Hong ^⁎

Source: In Molecular and Cellular Endocrinology 1 February 2025 597

Kynurenine promotes the immune escape of colorectal cancer cells via NAT10-mediated ac4C acetylation of PD-L1

Authors: Wang, Zaibiao ^{a, b}, Yin, Manman ^c, Zhou, Ruhang ^d, Li, Ming ^e, Peng, Jie ^b, Wang, Zhengguang ^{a, ⁎}

Source: In Clinics January-December 2025 80

Improvement of MASLD and MASH by suppression of hepatic N-acetyltransferase 10

Authors: Yanying Yang, Jie Lu, Yuejun Liu, Ni Zhang, Yunchen Luo, Mingyue Ma, Zhixia Dong, Shuo Zhang, Ming-Hua Zheng, Cheng-Chao Ruan, Xinjian Wan, Cheng Hu, Yan Lu, Xiaojing Ma, Bing Zhou

Source: Molecular Metabolism, Vol 89, Iss , Pp 102030- (2024)

Subject Terms: Metabolic dysfunction-associated steatotic liver disease, Metabolic dysfunction-associated steatohepatitis, N4-acetylcytidine, N-acetyltransferase 10, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877824001613; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/7a00448bffb64e5d8d2ae94cf6af4579

NAT10‐mediated ac4C‐modified ANKZF1 promotes tumor progression and lymphangiogenesis in clear‐cell renal cell carcinoma by attenuating YWHAE‐driven cytoplasmic retention of YAP1

Authors: Daojia Miao, Jian Shi, Qingyang Lv, Diaoyi Tan, Chuanyi Zhao, Zhiyong Xiong, Xiaoping Zhang

Source: Cancer Communications, Vol 44, Iss 3, Pp 361-383 (2024)

Subject Terms: clear‐cell renal cell carcinoma, N4‐acetylcytidine, N‐acetyltransferase 10, YAP1 nuclear import, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/e67f27c75b7149188ac9205b8488b3a6

Recent advances in the potential role of RNA N4-acetylcytidine in cancer progression

Authors: Shujun Zhang, Yafeng Liu, Xiao Ma, Xiaohui Gao, Yi Ru, Xinjun Hu, Xinyu Gu

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)

Subject Terms: N-acetyltransferase 10, N4-acetylcytidine, Tumor, mRNA, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/7732465550ee4a6abc25e5e4bedf53b2

N‐acetyltransferase 10 facilitates tumorigenesis of diffuse large B‐cell lymphoma by regulating AMPK/mTOR signalling through N4‐acetylcytidine modification of SLC30A9

Authors: Mengfei Ding, Zhuoya Yu, Tiange Lu, Shunfeng Hu, Xiangxiang Zhou, Xin Wang

Source: Clinical and Translational Medicine, Vol 14, Iss 7, Pp n/a-n/a (2024)

Subject Terms: Diffuse large B‐cell lymphoma, N4‐acetyclytidine, N‐acetyltransferase 10, Solute carrier family 30 member 9, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/5c184bd760d241fea8a61049d021fb5d

Remodelin delays non‐small cell lung cancer progression by inhibiting NAT10 via the EMT pathway

Authors: Quanwei Guo, Weijun Yu, Jianfeng Tan, Jianhua Zhang, Jin Chen, Shuan Rao, Xia Guo, Kaican Cai

Source: Cancer Medicine, Vol 13, Iss 11, Pp n/a-n/a (2024)

Subject Terms: epithelial‐to‐mesenchymal transition, invasion and metastasis, lung cancer, mouse xenograft, N‐acetyltransferase 10, patients‐derived organoids, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/100bce4fc8694e109c7aaf3281e2f497

N4-acetylcytidine acetylation of neurexin 2 in the spinal dorsal horn regulates hypersensitivity in a rat model of cancer-induced bone pain

Authors: Longsheng Xu, Shang Zheng, Liping Chen, Lei Yang, Shuyao Zhang, Beibei Liu, Kangli Shen, Qinli Feng, Qinghe Zhou, Ming Yao

Source: Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102200- (2024)

Subject Terms: MT: RNA and epigenetic editing Special Issue, cancer-induced bone pain, neurexin 2, RNA acetylation, N-acetyltransferase 10, synaptic remodeling, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253124000878; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/f185a962fe494e708e7e91ccb0c177ec

RNA binding profile analysis of N-acetyltransferase 10 in K562 cells

Authors: LI Gaoyuan, WANG Yanran, WANG Fang, YU Jia

Source: Jichu yixue yu linchuang, Vol 43, Iss 5, Pp 739-744 (2023)

Subject Terms: n-acetyltransferase 10, k562 cells, enhanced uv crosslinking, immunoprecipitation, and high-throughput sequencing(eclip-seq), Medicine

File Description: electronic resource

Relation: http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-5-739.pdf; https://doaj.org/toc/1001-6325

Access URL: https://doaj.org/article/2fec463f930441cab0ae63674ea365ca

Helicobacter pylori-induced NAT10 stabilizes MDM2 mRNA via RNA acetylation to facilitate gastric cancer progression

Authors: Min Deng, Long Zhang, Wenying Zheng, Jiale Chen, Nan Du, Meiqi Li, Weiqing Chen, Yonghong Huang, Ning Zeng, Yuanbin Song, Yongming Chen

Source: Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)

Subject Terms: Gastric cancer, N4-acetylcytidine, N-acetyltransferase 10, MDM2, p53, Helicobacter pylori, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/6a1f9ae9a4ce4f41a6fdf429a24e1789

N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA

Authors: Xiao Zheng, Qi Wang, You Zhou, Dachuan Zhang, Yiting Geng, Wenwei Hu, Changping Wu, Yufang Shi, Jingting Jiang

Source: Cancer Communications, Vol 42, Iss 12, Pp 1347-1366 (2022)

Subject Terms: Colon cancer, N‐acetyltransferase 10 (NAT10), N4‐acetylcytidine (ac4C), Ferroptosis suppressor protein 1 (FSP1), Ferroptosis, mRNA stability, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/7ee8b4338b024a0f92ee33a98827a034

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