Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.

Authors: Balboa, Diego, Barsby, Tom, Lithovius, Väinö, Saarimäki-Vire, Jonna, Omar-Hmeadi, Muhmmad, Dyachok, Oleg, Montaser, Hossam, Lund, Per-Eric, Yang, Mingyu, Ibrahim, Hazem, Näätänen, Anna, Chandra, Vikash, Vihinen, Helena, Jokitalo, Eija, Kvist, Jouni, Ustinov, Jarkko, Nieminen, Anni I., Kuuluvainen, Emilia, Hietakangas, Ville, Katajisto, Pekka

Source: Nature Biotechnology; Jul2022, Vol. 40 Issue 7, p1042-1055, 14p

Single-Cell Functional Genomics of Natural Killer Cell Interaction with Blood Cancers

Authors: Dufva, Olli ^*, Gandolfi, Sara ^*, Huuhtanen, Jani ^*, Dashevsky, Olga ^*, Saeed, Khalid ^*, Klievink, Jay ^*, Nygren, Petra Johanna ^*, Bouhlal, Jonas ^*, Lahtela, Jenni ^*, Näätänen, Anna ^*, Ghimire, Bishwa ^*, Hannunen, Tiina ^*, Ellonen, Pekka ^*, Duàn, Hanna ^*, Theodoropoulos, Jason ^*, Laajala, Essi ^*, Häkkinen, Aino ^*, Härkönen, Jouni ^*, Pölönen, Petri, Heinäniemi, Merja ^*, Yamano, Shizuka ^*, Shirasaki, Ryosuke ^*, Barbie, David ^*, Roth, Jennifer A. ^*, Romee, Rizwan, Sheffer, Michal ^*, Lähdesmäki, Harri ^*, Lee, Dean Anthony, De Matos Simoes, Ricardo ^*, Kankainen, Matti ^*, Mitsiades, Constantine S., Mustjoki, Satu

Source: In Blood 15 November 2022 140 Supplement 1:8343-8344

Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress.

Authors: Montaser, Hossam, Patel, Kashyap A., Balboa, Diego, Ibrahim, Hazem, Lithovius, Väinö, Näätänen, Anna, Chandra, Vikash, Demir, Korcan, Acar, Sezer, Ben-Omran, Tawfeg, Colclough, Kevin, Locke, Jonathan M., Wakeling, Matthew, Lindahl, Maria, Hattersley, Andrew T., Saarimäki-Vire, Jonna, Otonkoski, Timo

Source: Diabetes; Apr2021, Vol. 70 Issue 4, p1006-1018, 13p

Subject Terms: ENDOPLASMIC reticulum, HUMAN embryonic stem cells, DIABETES in children, ETIOLOGY of diabetes, DIABETES, NERVE growth factor, FLOW cytometry, RESEARCH, GENETIC mutation, IMMUNOHISTOCHEMISTRY, WESTERN immunoblotting, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, COMPARATIVE studies, ENZYME-linked immunosorbent assay, RESEARCH funding, POLYMERASE chain reaction, GLUCOSE tolerance tests

Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers.

Authors: Dufva, Olli^1,2,3 (AUTHOR), Gandolfi, Sara^1,2,3,4,5 (AUTHOR), Huuhtanen, Jani^1,2,3,6 (AUTHOR), Dashevsky, Olga^1,4,5,7,8 (AUTHOR), Duàn, Hanna^1,2,3 (AUTHOR), Saeed, Khalid^1,2 (AUTHOR), Klievink, Jay^1,2,3 (AUTHOR), Nygren, Petra^1,2,3 (AUTHOR), Bouhlal, Jonas^1,2,3 (AUTHOR), Lahtela, Jenni⁹ (AUTHOR), Näätänen, Anna⁹ (AUTHOR), Ghimire, Bishwa R.⁹ (AUTHOR), Hannunen, Tiina⁹ (AUTHOR), Ellonen, Pekka⁹ (AUTHOR), Lähteenmäki, Hanna^1,2 (AUTHOR), Rumm, Pauliina^1,2 (AUTHOR), Theodoropoulos, Jason^1,2 (AUTHOR), Laajala, Essi^1,2,3 (AUTHOR), Härkönen, Jouni¹⁰ (AUTHOR), Pölönen, Petri¹¹ (AUTHOR)

Source: Immunity (10747613). Dec2023, Vol. 56 Issue 12, p2816-2816. 1p.

Subject Terms: *FUNCTIONAL genomics, *KILLER cells, *NATURAL immunity, *BLOOD cells, *CANCER cells, *CELL death, *TUMOR suppressor genes