The evolving systemic biomarker milieu in obese ZSF1 rat model of human cardiometabolic syndrome: Characterization of the model and cardioprotective effect of GDF15.

Authors: Marina Stolina, Xin Luo, Denise Dwyer, Chun-Ya Han, Rhonda Chen, Ying Zhang, YuMei Xiong, Yinhong Chen, Jun Yin, Artem Shkumatov, Brandon Ason, Clarence Hale, Murielle M Véniant

Source: PLoS ONE, Vol 15, Iss 8, p e0231234 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2a28d72dc487472ba9726d8fb014b07f

Trefoil Factor 3 (TFF3) Is Regulated by Food Intake, Improves Glucose Tolerance and Induces Mucinous Metaplasia.

Authors: Hongfei Ge, Jonitha Gardner, Xiaosu Wu, Ingrid Rulifson, Jinghong Wang, Yumei Xiong, Jingjing Ye, Edward Belouski, Ping Cao, Jie Tang, Ki Jeong Lee, Suzanne Coberly, Xinle Wu, Jamila Gupte, Lynn Miao, Li Yang, Natalie Nguyen, Bei Shan, Wen-Chen Yeh, Murielle M Véniant, Yang Li, Helene Baribault

Source: PLoS ONE, Vol 10, Iss 6, p e0126924 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4471263?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/80d053555e6a4ed7aa6585d3c09320bb

Characterization of a novel glucokinase activator in rat and mouse models.

Authors: Min Lu, Pingping Li, Gautam Bandyopadhyay, William Lagakos, Walter E Dewolf, Taylor Alford, Mark Joseph Chicarelli, Lance Williams, Deborah A Anderson, Brian R Baer, Maralee McVean, Marion Conn, Murielle M Véniant, Peter Coward

Source: PLoS ONE, Vol 9, Iss 2, p e88431 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3922816?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6b5ff3c689ce4246a24878968b2d01da

FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein.

Authors: Richard Smith, Amy Duguay, Alice Bakker, Peng Li, Jennifer Weiszmann, Melissa R Thomas, Benjamin M Alba, Xinle Wu, Jamila Gupte, Li Yang, Jennitte Stevens, Agnes Hamburger, Stephen Smith, Jiyun Chen, Renee Komorowski, Kevin W Moore, Murielle M Véniant, Yang Li

Source: PLoS ONE, Vol 8, Iss 4, p e61432 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3632592?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/94370a4c5af3418bafae3672e5e4eb24

FGF21 promotes metabolic homeostasis via white adipose and leptin in mice.

Authors: Murielle M Véniant, Clarence Hale, Joan Helmering, Michelle M Chen, Shanaka Stanislaus, Jim Busby, Steven Vonderfecht, Jing Xu, David J Lloyd

Source: PLoS ONE, Vol 7, Iss 7, p e40164 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3391219?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/da87ceebbe5b427fb5ea0d3269c57f7b

Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes.

Authors: Randy Hecht, Yue-Sheng Li, Jeonghoon Sun, Ed Belouski, Michael Hall, Todd Hager, Junming Yie, Wei Wang, Dwight Winters, Stephen Smith, Chris Spahr, Lei-Ting Tam, Zhongnan Shen, Shanaka Stanislaus, Narumol Chinookoswong, Yvonne Lau, Allen Sickmier, Mark Leo Michaels, Thomas Boone, Murielle M Véniant, Jing Xu

Source: PLoS ONE, Vol 7, Iss 11, p e49345 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3507880?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4b03784bd0594b29a2d0316fd49362ba

A volumetric method for quantifying atherosclerosis in mice by using microCT: comparison to en face.

Authors: David J Lloyd, Joan Helmering, Stephen A Kaufman, James Turk, Matt Silva, Sergio Vasquez, David Weinstein, Brad Johnston, Clarence Hale, Murielle M Véniant

Source: PLoS ONE, Vol 6, Iss 4, p e18800 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3078927?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ae7f2e2eb1cd43f9a5a2073955438af5

Design and Synthesis of Conformationally Constrained Glucagon-Like Peptide-1 Derivatives with Increased Plasma Stability and Prolonged in Vivo Activity.

Authors: Les P. Miranda, Katherine A. Winters, Colin V. Gegg, Ankita Patel, Jennifer Aral, Jason Long, Jingwen Zhang, Stephanie Diamond, Mark Guido, Shanaka Stanislaus, Mark Ma, Hongyan Li, Mark J. Rose, Leszek Poppe, Murielle M. Véniant

Source: Journal of Medicinal Chemistry; Apr2008, Vol. 51 Issue 9, p2758-2765, 8p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

A transcriptomic and proteomic atlas of obesity and type 2 diabetes in cynomolgus monkeys

Authors: Xianglong Zhang, Liangbiao George Hu, Ying Lei, Marina Stolina, Oliver Homann, Songli Wang, Murielle M. Véniant, Yi-Hsiang Hsu

Source: Cell Reports, Vol 42, Iss 8, Pp 112952- (2023)

Subject Terms: CP: Metabolism, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723009634; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/c4207643efff4c418e487f21bf39ff25

Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis

Authors: Jiayan Guo, Hanbing Mei, Zhen Sheng, Qingyuan Meng, Murielle M. Véniant, Hong Yin

Source: Journal of Lipid Research, Vol 61, Iss 12, Pp 1764-1775 (2020)

Subject Terms: micro-ribonucleic acid, inflammation, apoptosis, familial hypercholesterolemia, low density lipoprotein receptor, animal model, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520600347; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/be048cbd37f34f32b5562a7f0151752c

Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism

Authors: Elizabeth A. Killion, Michelle Chen, James R. Falsey, Glenn Sivits, Todd Hager, Larissa Atangan, Joan Helmering, Jae Lee, Hongyan Li, Bin Wu, Yuan Cheng, Murielle M. Véniant, David J. Lloyd

Source: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/35bda07550384ea78b2522ff1a815550

GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

Authors: Shu-Chen Lu, Michelle Chen, Larissa Atangan, Elizabeth A. Killion, Renee Komorowski, Yuan Cheng, Chawita Netirojjanakul, James R. Falsey, Marina Stolina, Denise Dwyer, Clarence Hale, Shanaka Stanislaus, Todd Hager, Veena A. Thomas, John M. Harrold, David J. Lloyd, Murielle M. Véniant

Source: Cell Reports Medicine, Vol 2, Iss 5, Pp 100263- (2021)

Subject Terms: diet-induced obese mice, glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, monkeys, obesity, weight loss, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666379121000793; https://doaj.org/toc/2666-3791

Access URL: https://doaj.org/article/6fa1243f07684a9b91237d0446fb0986

Growth differentiation factor 15 as a potential therapeutic for treating obesity

Authors: Clarence Hale, Murielle M. Véniant

Source: Molecular Metabolism, Vol 46, Iss , Pp 101117- (2021)

Subject Terms: Nutritional stress, Food intake, GFRAL, Insulin resistance, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877820301915; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/b120044843414d4a81f51e8b7cfbcb6f

Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

Authors: Xiaoshan Min, Junming Yie, Jinghong Wang, Ben C. Chung, Ching-Shin Huang, Haoda Xu, Jie Yang, Liying Deng, Joanne Lin, Qing Chen, Christina M. Abbott, Caroline Gundel, Stephen A. Thibault, Tina Meng, Darren L. Bates, David J. Lloyd, Murielle M. Véniant, Zhulun Wang

Source: mAbs, Vol 12, Iss 1 (2020)

Subject Terms: GIPR, antagonistic antibody, crystallography, structure, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

Access URL: https://doaj.org/article/968f0a3d32354e02bad2c843bdc326da

Identification of three loci affecting HDL-cholesterol levels in a screen for chemically induced recessive mutations in mice[S]

Authors: Todd Juan, Murielle M. Véniant, Joan Helmering, Philip Babij, Daniel M. Baker, Michael A. Damore, Michael B. Bass, Tibor Gyuris, Mark Chhoa, Chi-Ming Li, Chris Ebeling, Julie Amato, George A. Carlson, David J. Lloyd

Source: Journal of Lipid Research, Vol 50, Iss 3, Pp 534-545 (2009)

Subject Terms: hypercholesterolemia, mutagenesis, ATP binding cassette transporter A1, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520308968; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/c01f6f3ea8d54e55b1a419cd8a290684

Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice

Authors: Constance H. Zlot, Laura M. Flynn, Murielle M. Véniant, Edward Kim, Martin Raabe, Sally P.A. McCormick, Patricia Ambroziak, Leslie M. McEvoy, Stephen G. Young

Source: Journal of Lipid Research, Vol 40, Iss 1, Pp 76-84 (1999)

Subject Terms: radioimmunoassay, transgenic mice, cholesterol, lipoproteins, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520333411; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/615181e0bdce417ea7895f10786451ba