Characteristics and outcomes of advanced melanoma patients with complete response and elective discontinuation of first‐line anti‐programmed death‐1 monotherapy: A real‐world multicentre observational cohort study

Authors: Ochenduszko, Sebastian, García Sanchez, Javier, Fita, María José Juan, González‐Barrallo, Inés, Herrero Colomina, Julio, Mujika, Karmele, Beveridge, Roberto Diaz, Martínez, Silverio Ros, Lafuente, Blanca Sánchez, Tomas, Alberto Cunquero, Jaime, Alfonso Berrocal, Cerezuela Fuentes, Pablo, Fra, Pablo Luna, Peeters, Alicia Gervás, Meana García, José Andrés, García, María Asunción Algarra, Altozano, Javier Perez, Cancela, Maria, Puchades, Almudena Mateu, Roca, Francisco Ferrando, Maiques, Inmaculada Maestu

Source: Pigment cell & melanoma research. 36(5):388-398

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190851893.0x000001&indx=1&recIds=ETOCvdc_100190851893.0x000001

Safety of combining dabrafenib plus trametinib in elderly BRAF V600 mutation-positive advanced melanoma patients: real-world data analysis of Spanish patients (ELDERLYMEL)

Authors: González-Barrallo, Inés, Castellón Rubio, Victoria Eugenia, Medina, Javier, España, Sofia, Mujika, Karmele, Majem, Margarita, Aguado, Carlos, Cabrera Suárez, Miguel Ángel, Palacio, Isabel, Osterloh, Lisa, Martínez-Fernández, Alejandro, García-Castaño, Almudena

Source: Melanoma research. 32(5):343-352

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187189455.0x000001&indx=1&recIds=ETOCvdc_100187189455.0x000001

Serum markers improve current prediction of metastasis development in early‐stage melanoma patients: a machine learning‐based study

Authors: Mancuso, Filippo, Lage, Sergio, Rasero, Javier, Díaz‐Ramón, José Luis, Apraiz, Aintzane, Pérez‐Yarza, Gorka, Ezkurra, Pilar Ariadna, Penas, Cristina, Sánchez‐Diez, Ana, García‐Vazquez, María Dolores, Gardeazabal, Jesús, Izu, Rosa, Mujika, Karmele, Cortés, Jesús, Asumendi, Aintzane, Boyano, María Dolores

Source: Molecular oncology. 14(8):1705-1718

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107597836.0x000001&indx=1&recIds=ETOCvdc_100107597836.0x000001

A Phase 1/2A trial of idroxioleic acid: first-in-class sphingolipid regulator and glioma cell autophagy inducer with antitumor activity in refractory glioma.

Authors: Lopez, Juanita, Lai-Kwon, Julia, Molife, Rhoda, Welsh, Liam, Tunariu, Nina, Roda, Desamparados, Fernández-García, Paula, Lladó, Victoria, McNicholl, Adrian G., Rosselló, Catalina A., Taylor, Richard J., Azaro, Analía, Rodón, Jordi, Sludden, Julieann, Veal, Gareth J., Plummer, Ruth, Urruticoechea, Ander, Lahuerta, Ainhara, Mujika, Karmele, Escribá, Pablo V.

Source: British Journal of Cancer; Sep2023, Vol. 129 Issue 5, p811-818, 8p

Adjuvant therapy versus watch-and-wait post surgery for stage III melanoma: a multicountry retrospective chart review

Authors: Mohr, Peter, Kiecker, Felix, Soriano, Virtudes, Dereure, Olivier, Mujika, Karmele, Saiag, Philippe, Utikal, Jochen, Koneru, Rama, Robert, Caroline, Cuadros, Florencia, Chacón, Matias, Villarroel, Rodrigo U, Najjar, Yana G, Kottschade, Lisa, Couselo, Eva M, Koruth, Roy, Guérin, Annie, Burne, Rebecca, Ionescu-Ittu, Raluca, Perrinjaquet, Maurice, Zager, Jonathan S

Source: Melanoma management. 6(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187916748.0x000001&indx=1&recIds=ETOCvdc_100187916748.0x000001

KEYNOTE-555 Cohort B: Efficacy, safety, and PK of pembrolizumab (pembro) 400 mg every 6 weeks (Q6W) as 1L therapy for advanced melanoma.

Authors: Jacobs, Conrad R., Rapoport, Bernardo Leon, Chan, Sze Wai, Ruff, Paul, Arance, Ana Maria, Mujika, Karmele, Anderson, James Robert, Lala, Mallika, Jain, Lokesh, Akala, Omobolaji Oyekunle, Chartash, Elliot, Cohen, Graham Lawrence

Source: Journal of clinical oncology. 39(15 suppl):9541-9541

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173223551.0x000001&indx=1&recIds=ETOCvdc_100173223551.0x000001

BRAF V600E mutational load as a prognosis biomarker in malignant melanoma.

Authors: Sevilla, Arrate, Morales, M. Celia, Ezkurra, Pilar A., Rasero, Javier, Velasco, Verónica, Cancho-Galan, Goikoane, Sánchez-Diez, Ana, Mujika, Karmele, Penas, Cristina, Smith, Isabel, Asumendi, Aintzane, Cortés, Jesús M., Boyano, Maria Dolores, Alonso, Santos

Source: PLoS ONE; 3/13/2020, Vol. 15 Issue 3, p1-9, 9p

Subject Terms: GENETIC load, MELANOMA, GLEASON grading system, INVERSE relationships (Mathematics), PROGNOSIS, MACHINE learning, CYCLIN-dependent kinase inhibitor-2A, GENETIC mutation

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Dabrafenib plus trametinib for compassionate use in metastatic melanoma: A STROBE-compliant retrospective observational postauthorization study.

Authors: Algarra, Salvador Martín, Soriano, Virtudes, Fernández-Morales, Luis, Berciano-Guerrero, Miguel-Ángel, Mujika, Karmele, Manzano, José Luis, Hernández, Teresa Puértolas, Soria, Ainara, Rodríguez-Abreu, Delvys, Arranz, Enrique Espinosa, Martínez, Javier Medina, Márquez-Rodas, Ivan, Rubió-Casadevall, Jordi, Ortega, María Eugenia, Jurado García, José Miguel, Lecumberri Biurrun, María José, Palacio, Isabel, de la Borbolla Artacho, María Rodríguez, Altozano, Javier Pérez, Castellón Rubio, Victoria Eugenia

Source: Medicine; 12/29/2017, Vol. 96 Issue 52, p1-7, 7p

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The Circulating Transcriptome as a Source of Biomarkers for Melanoma.

Authors: Solé, Carla, Tramonti, Daniela, Schramm, Maike, Goicoechea, Ibai, Armesto, María, Hernandez, Luiza I., Manterola, Lorea, Fernandez-Mercado, Marta, Mujika, Karmele, Tuneu, Anna, Jaka, Ane, Tellaetxe, Maitena, Friedländer, Marc R., Estivill, Xavier, Piazza, Paolo, Ortiz-Romero, Pablo L., Middleton, Mark R., Lawrie, Charles H.

Source: Cancers; Jan2019, Vol. 11 Issue 1, p70, 1p

Subject Terms: MELANOMA diagnosis, BIOMARKERS, CANCER patients, CELLULAR signal transduction, GENES, LONGITUDINAL method, PHOSPHOTRANSFERASES, POLYMERASE chain reaction, RNA, VASCULAR endothelial growth factors, RETROSPECTIVE studies, GENE expression profiling, SEQUENCE analysis

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