Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis

Authors: Snehangshu Kundu, Muhammad Akhtar Ali, Niklas Handin, Louis P. Conway, Veronica Rendo, Per Artursson, Liqun He, Daniel Globisch, Tobias Sjöblom

Source: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)

Subject Terms: Ras pathway, KRAS, BRAF, Colorectal cancer, Isogenic cell models, Integrative -omics analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/c6b41f70605140fe8ae77d5c5efb4251

Identification of NS2B-NS3 Protease Inhibitors for Therapeutic Application in ZIKV Infection: A Pharmacophore-Based High-Throughput Virtual Screening and MD Simulations Approaches

Authors: Hafiz Muzzammel Rehman, Muhammad Sajjad, Muhammad Akhtar Ali, Roquyya Gul, Muhammad Irfan, Muhammad Naveed, Munir Ahmad Bhinder, Muhammad Usman Ghani, Nadia Hussain, Amira S. A. Said, Amal H. I. Al Haddad, Mahjabeen Saleem

Source: Vaccines, Vol 11, Iss 1, p 131 (2023)

Subject Terms: Zika virus, e-pharmacophore approach, high-throughput virtual screening, ASINEX database, prime MM-GBSA, molecular dynamics simulation, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/11/1/131; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/7166cdbed75e4413b7faaf644336d313

Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells

Authors: Snehangshu Kundu, Muhammad Akhtar Ali, Niklas Handin, Narendra Padhan, Jimmy Larsson, Maria Karoutsou, Kenneth Ban, Jacek R. Wiśniewski, Per Artursson, Liqun He, Mats Hellström, Tobias Sjöblom

Source: Genome Medicine, Vol 10, Iss 1, Pp 1-13 (2018)

Subject Terms: Forward genetics, piggyBac transposon, Colorectal cancer, Ras pathway, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13073-017-0511-4; https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/e59e8395c9b944bfa4183f634a16c9e7

Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition

Authors: Chatarina Larsson, Muhammad Akhtar Ali, Tatjana Pandzic, Anders M. Lindroth, Liqun He, Tobias Sjöblom

Source: BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)

Subject Terms: Cancer, DIP2C, Gene knockout, rAAV-mediated gene targeting, Tumour cell biology, DNA methylation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-017-3472-5; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/ddac88b976794771a048274bda4d2f3e

SHISA3, an antagonist of the Wnt/β-catenin signaling, is epigenetically silenced and its ectopic expression suppresses growth in breast cancer.

Authors: Naveed Shahzad, Tehreem Munir, Mariam Javed, Fareeda Tasneem, Bilal Aslam, Moazzam Ali, Zeeshan Mutahir, Muhammad Akhtar Ali, Muhammad Umer, Munir Ahmad, Kokab Farooq, Umair Hassan, Tanveer Mustafa, Rana Salman Anjum, Abdul Rauf Shakoori

Source: PLoS ONE, Vol 15, Iss 7, p e0236192 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/bbd2a608abd049f88545ba336875f9fa

Large-scale genomic investigation of pediatric cholestasis reveals a novel hepatorenal ciliopathy caused by PSKH1 mutations

Authors: Maddirevula, Sateesh, Shagrani, Mohammad, Ji, Ae-Ri, Horne, Christopher R., Young, Samuel N., Mather, Lucy J., Alqahtani, Mashael, McKerlie, Colin, Wood, Geoffrey, Potter, Paul K., Abdulwahab, Firdous, AlSheddi, Tarfa, van der Woerd, Wendy L., van Gassen, Koen L.I., AlBogami, Dalal, Kumar, Kishwer, Muhammad Akhtar, Ali Syed, Binomar, Hiba, Almanea, Hadeel, Faqeih, Eissa, Fuchs, Sabine A., Scott, John W., Murphy, James M., Alkuraya, Fowzan S.

Source: In Genetics in Medicine November 2024 26(11)

Predictors and outcome of tetanus in newborns in slum areas of Karachi City: a case control study.

Authors: Sohaila, Arjumand, Shafiq, Yasir, Azim, Shazia, Baloch, Benazir, Muhammad Akhtar, Ali Syed, Tikmani, Shiyam Sunder, Brown, Nick

Source: BMC Research Notes; Aug2015, Vol. 8 Issue 1, p1-4, 4p, 3 Charts

Subject Terms: TETANUS in newborn infants, PUBLIC health, HEALTH outcome assessment, MORTALITY, DEVELOPING countries

Computational and molecular tools for scalable rAAV-mediated genome editing.

Authors: Stoimenov, Ivaylo, Muhammad Akhtar Ali, Pandzic, Tatjana, Sjöblom, Tobias

Source: Nucleic Acids Research; 3/11/2015, Vol. 43 Issue 5, p1-15, 15p

Risk factors for intraventricular haemorrhage in preterm infants from a tertiary care hospital of Karachi, Pakistan.

Authors: Haroon, Anila, Maheen, Humaira, Salat, Muhammad Sohail, Dileep, Dhanwanti, Ahmed, Shakeel, Muhammad Akhtar, Ali Syed, Ali, Syed Rehan

Source: Journal of the Pakistan Medical Association; Oct2014, Vol. 64 Issue 10, p1146-1150, 5p