Synergistic effects of mutation and glycosylation on disease progression

Authors: Shodai Suzuki, Motoyuki Itoh

Source: Frontiers in Molecular Biosciences, Vol 12 (2025)

Subject Terms: glycosylation, mutation, aging, Notch3, LDLR, APP, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2025.1550815/full; https://doaj.org/toc/2296-889X

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Neurological function is restored post-ischemic stroke in zebrafish, with aging exerting a deleterious effect on its pathology

Authors: Takamasa Mizoguchi, Ayumi Maki, Yuno Nakase, Mayu Okita, Yuina Minami, Misa Fukunaga, Motoyuki Itoh

Source: Brain Research Bulletin, Vol 221, Iss , Pp 111225- (2025)

Subject Terms: Zebrafish, Ischemic stroke, Aging, Learning ability, Cerebral vascular function, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

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Relation: http://www.sciencedirect.com/science/article/pii/S0361923025000371; https://doaj.org/toc/1873-2747

Access URL: https://doaj.org/article/8e8ef5d916234395aff4cf9760bb0377

Modeling of age-related neurological disease: utility of zebrafish

Authors: Tohgo Kanoh, Takamasa Mizoguchi, Ayako Tonoki, Motoyuki Itoh

Source: Frontiers in Aging Neuroscience, Vol 16 (2024)

Subject Terms: memory, aging, mouse, zebrafish, lifespan, cerebral blood vessel, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2024.1399098/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/20e6a995047a43b6b26b9e7731d86de5

Age-dependent dysfunction of the cerebrovascular system in the zebrafish telencephalon

Authors: Takamasa Mizoguchi, Mayu Okita, Yuina Minami, Misa Fukunaga, Ayumi Maki, Motoyuki Itoh

Source: Experimental Gerontology, Vol 178, Iss , Pp 112206- (2023)

Subject Terms: Zebrafish, Aging, Blood flow, Learning ability, Live imaging, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0531556523001274; https://doaj.org/toc/1873-6815

Access URL: https://doaj.org/article/281f7f53d6e1414f84d76ef9b0817c9b

Zebrafish behavior feature recognition using three-dimensional tracking and machine learning

Authors: Peng Yang, Hiro Takahashi, Masataka Murase, Motoyuki Itoh

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ea991d4753e54cbc961e4218a969ae1d

Py3-FITC: a new fluorescent probe for live cell imaging of collagen-rich tissues and ionocytes

Authors: Zhaotong Wang, Takamasa Mizoguchi, Takahito Kuribara, Masaya Nakajima, Mayuu Iwata, Yuka Sakamoto, Hiroyuki Nakamura, Toshihiko Murayama, Tetsuhiro Nemoto, Motoyuki Itoh

Source: Open Biology, Vol 11, Iss 2 (2021)

Subject Terms: live imaging, polypyrrole, collagen-rich tissue, ionocyte, zebrafish, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-2441

Access URL: https://doaj.org/article/bfb9c22df5f24ab5967660ee2058d2d7

Evaluation of Dexamethasone-Induced Osteoporosis In Vivo Using Zebrafish Scales

Authors: Siripat Chaichit, Takuto Sato, Huiqing Yu, Yu-ki Tanaka, Yasumitsu Ogra, Takamasa Mizoguchi, Motoyuki Itoh

Source: Pharmaceuticals, Vol 14, Iss 6, p 536 (2021)

Subject Terms: zebrafish, scale, cathepsin K, tartrate-resistant acid phosphatase, alkaline phosphatase, glucocorticoid-induced osteoporosis, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/14/6/536; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/9dc3ae2e8872459caf1a147e3e842a85

Age-Related Changes in Insulin-like Signaling Lead to Intermediate-Term Memory Impairment in Drosophila

Authors: Kento Tanabe, Motoyuki Itoh, Ayako Tonoki

Source: Cell Reports, Vol 18, Iss 7, Pp 1598-1605 (2017)

Subject Terms: insulin signaling, learning and memory, aging, fat body, Drosophila, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717301109; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/ef455cf0b69f4e7c9844541ab78a0d46

Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish

Authors: Shohei Mikami, Mizuki Nakaura, Atsuo Kawahara, Takamasa Mizoguchi, Motoyuki Itoh

Source: Biology Open, Vol 4, Iss 11, Pp 1576-1582 (2015)

Subject Terms: Mib2, Notch signalling, Neuronal development, Zebrafish, Ubiquitin ligase, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://bio.biologists.org/content/4/11/1576; https://doaj.org/toc/2046-6390

Access URL: https://doaj.org/article/bf120b25c13341a0b3bce299d661e8b6

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DEAD-box protein Ddx46 is required for the development of the digestive organs and brain in zebrafish.

Authors: Shunya Hozumi, Ryo Hirabayashi, Akio Yoshizawa, Mitsuko Ogata, Tohru Ishitani, Makiko Tsutsumi, Atsushi Kuroiwa, Motoyuki Itoh, Yutaka Kikuchi

Source: PLoS ONE, Vol 7, Iss 3, p e33675 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0033675&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a4b5cb3f904341528a09d3db2720f349

Transient activation of the Notch-her15.1 axis plays an important role in the maturation of V2b interneurons.

Authors: Takamasa Mizoguchi, Michi Fukada, Miku Iihama, Xuehui Song, Shun Fukagawa, Shuhei Kuwabara, Shuhei Omaru, Shin-ichi Higashijima, Motoyuki Itoh

Source: Development (09501991); Aug2020, Vol. 147 Issue 16, p1-7, 7p

Subject Terms: GABAERGIC neurons, CENTRAL nervous system, SPINAL cord, NOTCH genes, AXONS

Appetitive Memory with Survival Benefit Is Robust Across Aging in Drosophila.

Authors: Ayako Tonoki, Mina Ogasawara, Zhihua Yu, Motoyuki Itoh

Source: Journal of Neuroscience; 3/11/2020, Vol. 40 Issue 11, p2296-2304, 9p

Subject Terms: DROSOPHILA, DOPAMINERGIC neurons, DROSOPHILA melanogaster, NEURAL circuitry, SWEETNESS (Taste), TASTE perception

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Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway.

Authors: Takamasa Mizoguchi, Shoko Ikeda, Saori Watanabe, Michiko Sugawara, Motoyuki Itoh

Source: Proceedings of the National Academy of Sciences of the United States of America; 10/31/2017, Vol. 114 Issue 44, pE9280-E9289, 10p

Subject Terms: CELL migration, CATENINS, UBIQUITIN ligases, RAS oncogenes, F-actin, GUANOSINE triphosphatase, UBIQUITINATION, CELLULAR signal transduction

Epb41l5 competes with Delta as a substrate for Mib1 to coordinate specification and differentiation of neurons.

Authors: Miho Matsuda, Rand, Kinneret, Palardy, Greg, Nobuyuki Shimizu, Hiromi Ikeda, Nogare, Damian Dalle, Motoyuki Itoh, Chitnis, Ajay B.

Source: Development (09501991); 9/1/2016, Vol. 143 Issue 17, p3085-3096, 12p

Subject Terms: ERYTHROCYTE membranes, UBIQUITIN ligases, NOTCH signaling pathway, NEURONAL differentiation, NEURONS

Target Gene Knockdown by 2',4'-BNA/LNA Antisense Oligonucleotides in Zebrafish.

Authors: Motoyuki Itoh¹ mito@chiba-u.jp, Mizuki Nakaura¹, Takeshi Imanishi², Satoshi Obika²

Source: Nucleic Acid Therapeutics. Jun2014, Vol. 24 Issue 3, following p186-191. 7p.

Subject Terms: *GENES, *OLIGONUCLEOTIDES, *CELL culture, *ANIMAL models in research, *NUCLEIC acids, *ESCHERICHIA nucleic acids, *ZEBRA danio

Neurogenic phenotype of mind bomb mutants leads to severe patterning defects in the zebrafish hindbrain.

Authors: Stephanie Bingham, Summer Chaudhari, Gary Vanderlaan, Motoyuki Itoh, Ajay Chitnis, Anand Chandrasekhar

Source: Developmental Dynamics; Nov2003, Vol. 228 Issue 3, p451, 13p