Rapid and Integrated Bacterial Evolution Analysis unveils gene mutations and clinical risk of Klebsiella pneumoniae

Authors: Kojiro Uemura, Toyotaka Sato, Soh Yamamoto, Noriko Ogasawara, Jirachaya Toyting, Kotaro Aoki, Akira Takasawa, Masayuki Koyama, Atsushi Saito, Takayuki Wada, Kaho Okada, Yurie Yoshida, Koji Kuronuma, Chie Nakajima, Yasuhiko Suzuki, Motohiro Horiuchi, Kenichi Takano, Satoshi Takahashi, Hirofumi Chiba, Shin-ichi Yokota

Source: Nature Communications, Vol 16, Iss 1, Pp 1-17 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/193a9e70efcb4630ac8a06a3e5bcdd4c

Excitatory neuron-prone prion propagation and excitatory neuronal loss in prion-infected mice

Authors: Temuulen Erdenebat, Yusuke Komatsu, Nozomi Uwamori, Misaki Tanaka, Takashi Hoshika, Takeshi Yamasaki, Ayano Shimakura, Akio Suzuki, Toyotaka Sato, Motohiro Horiuchi

Source: Frontiers in Molecular Neuroscience, Vol 17 (2024)

Subject Terms: prion, PrPSc, excitatory neuron, inhibitory neuron, glutamatergic neuron, GABAergic neuron, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2024.1498142/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/079ebbb072a242da8431af74977db42c

Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target

Authors: Kazuki Yamamoto, Toyotaka Sato, Aili Hao, Kenta Asao, Rintaro Kaguchi, Shintaro Kusaka, Radhakrishnam Raju Ruddarraju, Daichi Kazamori, Kiki Seo, Satoshi Takahashi, Motohiro Horiuchi, Shin-ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8640ff4ee8c741c084f0f712332ebe3b

Characterization of Shiga Toxin-producing Escherichia coli Isolated from Cattle Around Ulaanbaatar City, Mongolia

Authors: Erdenebat Bulgan, Zolzaya Byambajav, Narantuya Ayushjav, Yuji Hirai, Misaki Tanaka, Nyam-Osor Purevdorj, Sandagdorj Badrakh, Akio Suzuki, Yusuke Komatsu, Toyotaka Sato, Motohiro Horiuchi

Source: Journal of Food Protection, Vol 87, Iss 7, Pp 100294- (2024)

Subject Terms: Enterohemorrhagic Escherichia coli, Foodborne disease, Mongolia, Shiga toxin-producing Escherichia coli, Food processing and manufacture, TP368-456, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0362028X24000784; https://doaj.org/toc/0362-028X

Access URL: https://doaj.org/article/24d81ee0b59748e696493374854cf8e7

Traces of pandemic fluoroquinolone-resistant Escherichia coli clone ST131 transmitted from human society to aquatic environments and wildlife in Japan

Authors: Toyotaka Sato, Kojiro Uemura, Mitsuru Yasuda, Aiko Maeda, Toshifumi Minamoto, Kazuki Harada, Michiyo Sugiyama, Shiori Ikushima, Shin-ichi Yokota, Motohiro Horiuchi, Satoshi Takahashi, Testuo Asai

Source: One Health, Vol 18, Iss , Pp 100715- (2024)

Subject Terms: Antimicrobial resistance, Escherichia coli, Fluoroquinolone resistance, ST131, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352771424000417; https://doaj.org/toc/2352-7714

Access URL: https://doaj.org/article/ba4a934b73964ee4bd1d40dc70749108

High prevalence of colistin heteroresistance in specific species and lineages of Enterobacter cloacae complex derived from human clinical specimens

Authors: Shota Fukuzawa, Toyotaka Sato, Kotaro Aoki, Soh Yamamoto, Noriko Ogasawara, Chie Nakajima, Yasuhiko Suzuki, Motohiro Horiuchi, Satoshi Takahashi, Shin-ichi Yokota

Source: Annals of Clinical Microbiology and Antimicrobials, Vol 22, Iss 1, Pp 1-18 (2023)

Subject Terms: Enterobacter cloacae complex, Colistin, Heteroresistance, arnT, PhoPQ, Average nucleotide identity (ANI), Therapeutics. Pharmacology, RM1-950, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/1476-0711

Access URL: https://doaj.org/article/c31abc286faa490d977a79d980f717d7

Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY

Authors: Takeshi Nakaya, Miyuki Yabe, Ellene H. Mashalidis, Toyotaka Sato, Kazuki Yamamoto, Yuta Hikiji, Akira Katsuyama, Motoko Shinohara, Yusuke Minato, Satoshi Takahashi, Motohiro Horiuchi, Shin-ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa

Source: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/16ee9423619a405db124dcc0caf62ed5

Colistin Susceptibility in Companion Animal-Derived Escherichia coli, Klebsiella spp., and Enterobacter spp. in Japan: Frequent Isolation of Colistin-Resistant Enterobacter cloacae Complex

Authors: Toyotaka Sato, Kazuki Harada, Masaru Usui, Shin-ichi Yokota, Motohiro Horiuchi

Source: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Subject Terms: bacteria, Enterobacterales, Enterobacter spp, antimicrobial resistance, colistin, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2022.946841/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/0b6434a19b3d497b9cbf3e2da5c546fd

Refeeding activates neurons in the dorsomedial hypothalamus to inhibit food intake and promote positive valence

Authors: Daigo Imoto, Izumi Yamamoto, Hirokazu Matsunaga, Toya Yonekura, Ming-Liang Lee, Kan X. Kato, Takeshi Yamasaki, Shucheng Xu, Taiga Ishimoto, Satoshi Yamagata, Ken-ichi Otsuguro, Motohiro Horiuchi, Norifumi Iijima, Kazuhiro Kimura, Chitoku Toda

Source: Molecular Metabolism, Vol 54, Iss , Pp 101366- (2021)

Subject Terms: Refeeding, Hypothalamus, Satiety, Opioid, Positive valence, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877821002131; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/e4073d3d75374f94930b616d55d069ef

Research Note: Antimicrobial resistance of Campylobacter species isolated from chickens near Ulaanbaatar city, Mongolia

Authors: Zolzaya Byambajav, Erdenebat Bulgan, Yuji Hirai, Momoko Nakayama, Misaki Tanaka, Yurika Nitta, Akio Suzuki, Takashi Umemura, Bold Altankhuu, Alimaa Tsagaan, Batbaatar Vanaabaatar, Erdenebaatar Janchivdorj, Nyam-Osor Purevdorj, Narantuya Ayushjav, Takeshi Yamasaki, Motohiro Horiuchi

Source: Poultry Science, Vol 100, Iss 3, Pp 100916- (2021)

Subject Terms: antimicrobial resistance, Campylobacter, fluoroquinolone, Mongolia, Animal culture, SF1-1100

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0032579120309676; https://doaj.org/toc/0032-5791

Access URL: https://doaj.org/article/9853fce96c96485cb79d4bb32c85f055

Isolation of Human Lineage, Fluoroquinolone-Resistant and Extended-β-Lactamase-Producing Escherichia coli Isolates from Companion Animals in Japan

Authors: Toyotaka Sato, Shin-ichi Yokota, Tooru Tachibana, Satoshi Tamai, Shigeki Maetani, Yutaka Tamura, Motohiro Horiuchi

Source: Antibiotics, Vol 10, Iss 12, p 1463 (2021)

Subject Terms: fluoroquinolone-resistance, ESBL, Escherichia coli, dogs, cats, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/10/12/1463; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/e4e89933a75c4f1cace89246ae166cf2

Enhanced phosphorylation of PERK in primary cultured neurons as an autonomous neuronal response to prion infection.

Authors: Misaki Tanaka, Takeshi Yamasaki, Rie Hasebe, Akio Suzuki, Motohiro Horiuchi

Source: PLoS ONE, Vol 15, Iss 6, p e0234147 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/72bb332235a949609af3a21c4fa1d712

Tracking and clarifying differential traits of classical- and atypical L-type bovine spongiform encephalopathy prions after transmission from cattle to cynomolgus monkeys.

Authors: Ken'ichi Hagiwara, Yuko Sato, Yoshio Yamakawa, Hideyuki Hara, Minoru Tobiume, Yuko Okemoto-Nakamura, Tetsutaro Sata, Motohiro Horiuchi, Hiroaki Shibata, Fumiko Ono

Source: PLoS ONE, Vol 14, Iss 5, p e0216807 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/50e3abb1243e4107a313e32e62fce864

Enhancement of binding avidity by bivalent binding enables PrPSc-specific detection by anti-PrP monoclonal antibody 132.

Authors: Akio Suzuki, Takeshi Yamasaki, Rie Hasebe, Motohiro Horiuchi

Source: PLoS ONE, Vol 14, Iss 6, p e0217944 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/769b497b07bf459389e35642f45465e9

Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells.

Authors: Takeshi Yamasaki, Akio Suzuki, Rie Hasebe, Motohiro Horiuchi

Source: PLoS ONE, Vol 9, Iss 9, p e106516 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25181483/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d2059fa7fd464cee954a89f3fbabbb44

Solid-Phase Total Synthesis of Plusbacin A3.

Authors: Kazuki Takashina, Akira Katsuyama, Rintaro Kaguchi, Kazuki Yamamoto, Toyotaka Sato, Satoshi Takahashi, Motohiro Horiuchi, Shin-ichi Yokota, Satoshi Ichikawa

Source: Organic Letters; 3/25/2022, Vol. 24 Issue 11, p2253-2257, 5p

Estimation of prion infectivity in tissues of cattle infected with atypical BSE by real time-quaking induced conversion assay.

Authors: Kazuhei SAWADA, Akio SUZUKI, Takeshi YAMASAKI, Yoshifumi IWAMARU, Yuichi MATSUURA, Kohtaro MIYAZAWA, Kentaro MASUJIN, Ryuichiro ATARASHI, Motohiro HORIUCHI

Source: Journal of Veterinary Medical Science; 2019, Vol. 81 Issue 6, p846-850, 5p

Subject Terms: BOVINE spongiform encephalopathy, PRIONS, NERVE tissue, CATTLE, ADRENAL glands, SUPERIOR colliculus, CATTLE diseases

Listeria monocytogenes serotype 4b strains replicate in monocytes/macrophages more than the other serotypes.

Authors: Rie HASEBE, Ryo NAKAO, Aiko OHNUMA, Takeshi YAMASAKI, Hirofumi SAWA, Shinji TAKAI, Motohiro HORIUCHI

Source: Journal of Veterinary Medical Science; Jun2017, Vol. 79 Issue 6, p962-969, 8p

Subject Terms: LISTERIA monocytogenes, SEROTYPES, MONOCYTES, LABORATORY mice, DNA replication

Alternative BSE Risk Assessment Methodology for Beef and Beef Offal Imported into Japan.

Authors: Yasuhiro YOSHIKAWA, Motohiro HORIUCHI, Naotaka ISHIGURO, Mutsuyo KADOHIRA, Satoshi KAI, Hidehiro MIZUSAWA, Chisato NAGATA, Takashi ONODERA, Tetsutaro SATA, Toshiyuki TSUTSUI, Masahito YAMADA, Shigeki YAMAMOTO

Source: Journal of Veterinary Medical Science; Aug2012, Vol. 74 Issue 8, p959-968, 10p

Subject Terms: BOVINE spongiform encephalopathy, RISK assessment, BEEF, MEAT, CATTLE

Geographic Terms: JAPAN

Sulfated glycans and elevated temperature stimulate PrP^Sc-dependent cell-free formation of protease-resistant prion protein.

Authors: Cai'ne Wong, Liang-Wen Xiong, Motohiro Horiuchi, Lynne Raymond, Kathy Wehrly, Chesebro, Bruce, Caughey, Byron

Source: EMBO Journal; 2/1/2001, Vol. 20 Issue 3, p377-386, 10p

Subject Terms: PROTEOLYTIC enzymes, PRIONS, CHRONIC wasting disease, SCRAPIE, PRION diseases in animals, GLYCOSAMINOGLYCANS