Collagen turnover biomarkers to predict outcome of patients with biliary cancer

Authors: Leonard Kaps, Muhammed A. Genc, Markus Moehler, Stephan Grabbe, Jörn M. Schattenberg, Detlef Schuppan, Rasmus Sund Pedersen, Morten A. Karsdal, Philipp Mildenberger, Annett Maderer, Nicholas Willumsen

Source: BMC Gastroenterology, Vol 25, Iss 1, Pp 1-14 (2025)

Subject Terms: Tumor marker, Extracellular matrix, Gastrointestinal cancer, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1471-230X

Access URL: https://doaj.org/article/9c41629946164b48865879af38d42fa4

Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids

Authors: Janesh Pillay, Antine W. Flikweert, Matijs van Meurs, Marco J. Grootenboers, Simone van der Sar-van der Brugge, Peter H. J. van der Voort, Morten A. Karsdal, Jannie M. B. Sand, Diana J. Leeming, Janette K. Burgess, Jill Moser

Source: Respiratory Research, Vol 26, Iss 1, Pp 1-13 (2025)

Subject Terms: COVID-19, ARDS, Extracellular matrix, Neo-epitopes, Corticosteroids, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/f413177afe17487388873b1bb882d368

Association between type III collagen degradation and local tissue damage of a single joint

Authors: Christian S. Thudium, Sten Rasmussen, Morten A. Karsdal, Anne-Christine Bay-Jensen

Source: Osteoarthritis and Cartilage Open, Vol 6, Iss 4, Pp 100527- (2024)

Subject Terms: Biomarkers, ECM, Revision surgery, Collagen, Joint replacement, Osteoarthritis, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2665913124000943; https://doaj.org/toc/2665-9131

Access URL: https://doaj.org/article/ea2442c807d1402bb80cfccc878e23d5

The fibroid phenotype of biological naïve patients with rheumatoid arthritis are less likely to respond to anti-IL-6R treatment

Authors: Sofie Falkenløve Madsen, Dovile Sinkeviciute, Christian S. Thudium, Morten A. Karsdal, Anne-Christine Bay-Jensen

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9dfeba6e89044064af703a8e285e3add

Changes in type VI collagen degradation reflect clinical response to treatment in rheumatoid arthritis patients treated with tocilizumab

Authors: Christian S. Thudium, Peder Frederiksen, Morten A. Karsdal, Anne-Christine Bay-Jensen

Source: Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-10 (2024)

Subject Terms: Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/d632f2e3b3814913af442492e9664f63

Neutrophil-mediated type IV collagen degradation is elevated in patients with mild endoscopic ulcerative colitis reflecting early mucosal destruction

Authors: Marta S. Alexdottir, Martin Pehrsson, Viktor Domislovic, Line E. Godskesen, Aleksander Krag, Jens Kjeldsen, Marko Brinar, Ana Barisic, Anne-Christine Bay-Jensen, Morten A. Karsdal, Zeljko Krznaric, Joachim H. Mortensen

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/36ce61ebf75c4f13b829c1c0aa30a870

Levels of type XVII collagen (BP180) ectodomain are elevated in circulation from patients with multiple cancer types and is prognostic for patients with metastatic colorectal cancer

Authors: Marina Crespo-Bravo, Jeppe Thorlacius-Ussing, Neel I. Nissen, Rasmus S. Pedersen, Mogens K. Boisen, Maria Liljefors, Astrid Z. Johansen, Julia S. Johansen, Morten A. Karsdal, Nicholas Willumsen

Source: BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)

Subject Terms: Collagens, ECM, Non-invasive biomarker, Epithelial damage, Type XVII collagen, Ectodomain, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/8e62a07ff1ff43e4a58ac916255a431b

Urinary Endotrophin and Long-term Outcomes in Kidney Transplant Recipients

Authors: Firas F. Alkaff, MD, Daan Kremer, MD, Olivier Thaunat, MD, PhD, Stefan P. Berger, MD, PhD, Jacob van den Born, PhD, Federica Genovese, PhD, Morten A. Karsdal, PhD, Stephan J. L. Bakker, MD, PhD, Daniel G. K. Rasmussen, PhD, Martin Tepel, MD

Source: Transplantation Direct, Vol 10, Iss 3, p e1591 (2024)

Subject Terms: Surgery, RD1-811

File Description: electronic resource

Relation: http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001591; https://doaj.org/toc/2373-8731

Access URL: https://doaj.org/article/c8aa90a7f031435095eeb219f8b3ce33

Collagen turnover is associated with cardiovascular autonomic and peripheral neuropathy in type 1 diabetes: novel pathophysiological mechanism?

Authors: Christian S. Hansen, Daniel G. K. Rasmussen, Tine W. Hansen, Signe Holm Nielsen, Simone Theilade, Morten A. Karsdal, Federica Genovese, Peter Rossing

Source: Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-11 (2023)

Subject Terms: Cardiovascular autonomic neuropathy, Collagen, Diabetes, Inflammation, Peripheral neuropathy, Cardiovascular disease, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/ca02b1a0dc2443d4a334af2abebf1d41

Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV

Authors: Leona Dold, Mette J. Nielsen, Michael Praktiknjo, Carolynne Schwarze-Zander, Christoph Boesecke, Jan-Christian Wasmuth, Jenny Bischoff, Jürgen Kurt Rockstroh, Morten A. Karsdal, Ulrich Spengler, Jonel Trebicka, Christian P. Strassburg, Diana J. Leeming, Bettina Langhans

Source: BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-9 (2023)

Subject Terms: PC3X, PRO-C5, PRO-C6, HIV, Liver fibrosis, Hepatic steatosis, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/a44fd9ba1d1f4da09ed1aa2b27340010

Endotrophin is a risk marker of complications in CANagliflozin cardioVascular Assessment Study (CANVAS): a randomized controlled trial

Authors: Daniel Guldager Kring Rasmussen, Michael K. Hansen, Joseph Blair, Timothy A. Jatkoe, Bruce Neal, Morten A. Karsdal, Federica Genovese

Source: Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-13 (2022)

Subject Terms: Biomarker, Collagen, Diabetes, Endotrophin, Extracellular matrix, Fibrosis, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/13be6d48294743ed834a55a7a2412dc7

Pathological tissue formation and degradation biomarkers correlate with patient reported pain outcomes: an explorative study

Authors: Anne C. Bay-Jensen, Mukundan Attur, Jonathan Samuels, Christian S. Thudium, Steven B. Abramson, Morten A. Karsdal

Source: Osteoarthritis and Cartilage Open, Vol 5, Iss 3, Pp 100379- (2023)

Subject Terms: Protein, Epitope, Assay, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2665913123000468; https://doaj.org/toc/2665-9131

Access URL: https://doaj.org/article/2f013bd017994433b08da053806363eb

Regulation of tumor immunity and immunotherapy by the tumor collagen extracellular matrix

Authors: Dallas B. Flies, Solomon Langermann, Christina Jensen, Morten A. Karsdal, Nicholas Willumsen

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: cancer biology, collagen, cancer immunotherapy, ECM - extracellular matrix, LAIR-1, tumor microenvironment (TME), Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1199513/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/f18f4fb63fd74d4aaf0dd5c1f40c603d

Endotrophin, a fibroblast matrikine, may be a driver of fibroblast activation in fibro-inflammatory diseases

Authors: Alexander L. Reese-Petersen, Federica Genovese, Lei Zhao, Glen Banks, David A. Gordon, Morten A. Karsdal

Source: Frontiers in Molecular Biosciences, Vol 10 (2023)

Subject Terms: fibrosis, biomarkers, heart failure, collagen, ECM, extracellular matrix, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1228232/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/6f6c2f51ad9b4b958f3b0683ad4e35f5

PRO-C3 is a predictor of clinical outcomes in distinct cohorts of patients with advanced liver disease

Authors: Mette J. Nielsen, Grace E. Dolman, Rebecca Harris, Peder Frederiksen, Jane Chalmers, Jane I. Grove, William L. Irving, Morten A. Karsdal, Keyur Patel, Diana Julie Leeming, Indra Neil Guha

Source: JHEP Reports, Vol 5, Iss 6, Pp 100743- (2023)

Subject Terms: Cirrhosis, Biomarker, Outcome, Extracellular matrix, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923000745; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/0e7fd31c9d4f4821b97670a60b11b3fe

Pretransplant endotrophin predicts delayed graft function after kidney transplantation

Authors: Martin Tepel, Firas F. Alkaff, Daan Kremer, Stephan J. L. Bakker, Olivier Thaunat, Subagini Nagarajah, Qais Saleh, Stefan P. Berger, Jacob van den Born, Nicoline V. Krogstrup, Marie B. Nielsen, Rikke Nørregaard, Bente Jespersen, Nadja Sparding, Federica Genovese, Morten A. Karsdal, Daniel G. K. Rasmussen

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/dc8376e1ebb242f882d7aef601a70e13

Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis

Authors: Henrik Jessen, Nils Hoyer, Thomas S. Prior, Peder Frederiksen, Sarah R. Rønnow, Morten A. Karsdal, Diana J. Leeming, Elisabeth Bendstrup, Jannie M. B. Sand, Saher B. Shaker

Source: BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)

Subject Terms: Type VI collagen, Biomarkers, Cohort study, Extracellular matrix, Idiopathic pulmonary fibrosis, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/51e299aa98f7485bbe5ebc94f9457fa2

PRO‐C3, a Serological Marker of Fibrosis, During Childhood and Correlations With Fibrosis in Pediatric NAFLD

Authors: Catherine C. Cohen, Eduardo Castillo‐Leon, Alton B. Farris, Shelley A. Caltharp, Rebecca L. Cleeton, Elizabeth M. Sinclair, Diane E. Shevell, Morten A. Karsdal, Mette Juul Fisker Nielsen, Diana J. Leeming, Miriam B. Vos

Source: Hepatology Communications, Vol 5, Iss 11, Pp 1860-1872 (2021)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/2471-254X

Access URL: https://doaj.org/article/7a7dda75194c44619e8a03c2243eac4f

Serological assessment of collagen fragments and tumor fibrosis may guide immune checkpoint inhibitor therapy

Authors: Christina Jensen, Neel I. Nissen, Claus S. Von Arenstorff, Morten A. Karsdal, Nicholas Willumsen

Source: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-11 (2021)

Subject Terms: Biomarker, Immune checkpoint inhibitor, Immunotherapy, T cells, Tumor fibrosis, Fibroblasts, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/4a90731714c645489f05bc2af58b49ca

Dynamic compression inhibits cytokine-mediated type II collagen degradation

Authors: Amalie Engstrøm, Frederik S. Gillesberg, Anne-Christine Bay Jensen, Morten A. Karsdal, Christian S. Thudium

Source: Osteoarthritis and Cartilage Open, Vol 4, Iss 4, Pp 100292- (2022)

Subject Terms: Asteoarthritis, Articular cartilage, Dynamic mechanical compression, Bovine explants, Type II collagen, Translational research, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2665913122000607; https://doaj.org/toc/2665-9131

Access URL: https://doaj.org/article/53b84f3bc6e84a7b8def9570cbe1cdfa