The antimicrobial potential of adarotene derivatives against Staphylococcus aureus strains

Authors: Princiotto, Salvatore, Casciaro, Bruno, G. Temprano, Alvaro, Musso, Loana, Sacchi, Francesca, Loffredo, Maria Rosa, Cappiello, Floriana, Sacco, Federica, Raponi, Giammarco, Fernandez, Virginia Perez, Iucci, Teresa, Mangoni, Maria Luisa, Mori, Mattia, Dallavalle, Sabrina, Pisano, Claudio

Source: In Bioorganic Chemistry April 2024 145

Antimalarial drugs: what's new in the patents?

Authors: Lopes, Elizabeth A., Santos, Maria M. M., Mori, Mattia

Source: Expert opinion on therapeutic patents. 33(3):151-168

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Targeting the tubulin C-terminal tail by charged small moleculesThis paper is dedicated to the late Professor Maurizio Botta, University of Siena.Electronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2ob01910h

Authors: Li, Shuo, Mori, Mattia, Yang, Mingyan, Elfazazi, Soumia, Hortigüela, Rafael, Chan, Peter, Feng, Xinyue, Risinger, April, Yang, Zhiyou, Oliva, María Ángela, Fernando Díaz, J., Fang, Wei-Shuo

Source: Organic & biomolecular chemistry. 21(1):153-162

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Inhibitors of UHRF1 base flipping activity showing cytotoxicity against cancer cells

Authors: Ciaco, Stefano, Mazzoleni, Viola, Javed, Aqib, Eiler, Sylvia, Ruff, Marc, Mousli, Marc, Mori, Mattia, Mély, Yves

Source: In Bioorganic Chemistry August 2023 137

Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors

Authors: Espadinha, Margarida, Lopes, Elizabeth A., Marques, Vanda, Amaral, Joana D., dos Santos, Daniel J.V.A., Mori, Mattia, Daniele, Simona, Piccarducci, Rebecca, Zappelli, Elisa, Martini, Claudia, Rodrigues, Cecília M.P., Santos, Maria M.M.

Source: In European Journal of Medicinal Chemistry 5 November 2022 241

Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment

Authors: Di Maria, Salvatore, Picarazzi, Francesca, Mori, Mattia, Cianciusi, Annarita, Carbone, Anna, Crespan, Emmanuele, Perini, Cecilia, Sabetta, Samantha, Deplano, Serenella, Poggialini, Federica, Molinari, Alessio, Aronne, Rossella, Maccioni, Elias, Maga, Giovanni, Angelucci, Adriano, Schenone, Silvia, Musumeci, Francesca, Dreassi, Elena

Source: In Bioorganic Chemistry November 2022 128

Identification of Small Molecular Chaperones Binding P23H Mutant Opsin through an In Silico Structure-Based Approach

Authors: Picarazzi, Francesca, Zuanon, Marika, Pasqualetto, Gaia, Cammarone, Silvia, Romeo, Isabella, Young, Mark T., Brancale, Andrea, Bassetto, Marcella, Mori, Mattia

Source: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 62(22):5794-5805

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Thienoguanosine, a unique non-perturbing reporter for investigating rotational dynamics of DNA duplexes and their complexes with proteins

Authors: Grytsyk, Natalia, Richert, Ludovic, Didier, Pascal, Dziuba, Dmytro, Ciaco, Stefano, Mazzoleni, Viola, Lequeu, Thiebault, Mori, Mattia, Tor, Yitzhak, Martinez-Fernandez, Lara, Improta, Roberto, Mély, Yves

Source: International journal of biological macromolecules. 213:210-225

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Acipimox inhibits human carbonic anhydrases

Authors: Mori, Mattia, Supuran, Claudiu T.

Source: Journal of enzyme inhibition and medicinal chemistry. 37(1):672-679

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Esc peptides and derivatives potentiate the activity of CFTR with gating defects and display antipseudomonal activity in cystic fibrosis-like lung disease: Peptides for dual antimicrobial and CFTR potentiator function: L. Ferrera et al.

Authors: Ferrera, Loretta, Cappiello, Floriana, Venturini, Arianna, Lu, Hexin, Casciaro, Bruno, Cappella, Giacomo, Bontempi, Giulio, Corrente, Alessandra, Strippoli, Raffaele, Zara, Federico, Di, Y. Peter, Galietta, Luis J. V., Mori, Mattia, Mangoni, Maria Luisa

Source: Cellular & Molecular Life Sciences; 3/18/2025, Vol. 82 Issue 1, p1-23, 23p

Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity

Authors: Lopes, Elizabeth A., Mestre, Raquel, Fontinha, Diana, Legac, Jenny, Pei, Jinxin V., Sanches-Vaz, Margarida, Mori, Mattia, Lehane, Adele M., Rosenthal, Philip J., Prudêncio, Miguel, Santos, Maria M.M.

Source: In European Journal of Medicinal Chemistry 5 June 2022 236

SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells

Authors: Hammer, Quirin, Dunst, Josefine, Christ, Wanda, Picarazzi, Francesca, Wendorff, Mareike, Momayyezi, Pouria, Huhn, Oisín, Netskar, Herman K., Maleki, Kimia T., García, Marina, Sekine, Takuya, Sohlberg, Ebba, Azzimato, Valerio, Aouadi, Myriam, Degenhardt, Frauke, Franke, Andre, Spallotta, Francesco, Mori, Mattia, Michaëlsson, Jakob, Björkström, Niklas K., Rückert, Timo, Romagnani, Chiara, Horowitz, Amir, Klingström, Jonas, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan

Source: In Cell Reports 8 March 2022 38(10)

Conformational insights into the C-terminal mutations of human rhodopsin in retinitispigmentosa

Authors: Picarazzi, Francesca, Manetti, Fabrizio, Marigo, Valeria, Mori, Mattia

Source: In Journal of Molecular Graphics and Modelling January 2022 110

Hepatic miR-144 Drives Fumarase Activity Preventing NRF2 Activation During Obesity

Authors: Azzimato, Valerio, Chen, Ping, Barreby, Emelie, Morgantini, Cecilia, Levi, Laura, Vankova, Ana, Jager, Jennifer, Sulen, André, Diotallevi, Marina, Shen, Joanne X., Miller, Anne, Ellis, Ewa, Rydén, Mikael, Näslund, Erik, Thorell, Anders, Lauschke, Volker M., Channon, Keith M., Crabtree, Mark J., Haschemi, Arvand, Craige, Siobhan M., Mori, Mattia, Spallotta, Francesco, Aouadi, Myriam

Source: In Gastroenterology December 2021 161(6):1982-1997

Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma

Authors: Infante, Paola, Malfanti, Alessio, Quaglio, Deborah, Balducci, Silvia, De Martin, Sara, Bufalieri, Francesca, Mastrotto, Francesca, Basili, Irene, Garofalo, Mariangela, Lospinoso Severini, Ludovica, Mori, Mattia, Manni, Isabella, Moretti, Marta, Nicoletti, Carmine, Piaggio, Giulia, Caliceti, Paolo, Botta, Bruno, Ghirga, Francesca, Salmaso, Stefano, Di Marcotullio, Lucia

Source: In Cancer Letters 28 February 2021 499:220-231

Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors

Authors: Bonandi, Elisa, Mori, Mattia, Infante, Paola, Basili, Irene, Di Marcotullio, Lucia, Calcaterra, Andrea, Catti, Federica, Botta, Bruno, Passarella, Daniele

Source: Chemistry. 27(32):8350-8357

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A unique high-diversity natural product collection as a reservoir of new therapeutic leads

Authors: Ghirga, Francesca, Quaglio, Deborah, Mori, Mattia, Cammarone, Silvia, Iazzetti, Antonia, Goggiamani, Antonella, Ingallina, Cinzia, Botta, Bruno, Calcaterra, Andrea

Source: Organic chemistry frontiers. 8(5):996-1025

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Repurposing drugs for the management of COVID-19

Authors: Cusinato, Jacopo, Cau, Ylenia, Calvani, Anna Maria, Mori, Mattia

Source: Expert opinion on therapeutic patents. 31(4):295-307

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Potency and Selectivity Optimization of Tryptophanol‐Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer

Authors: Barcherini, Valentina, Almeida, Joana, Lopes, Elizabeth A., Wang, Mi, Magalhães e Silva, Diogo, Mori, Mattia, Wang, Shaomeng, Saraiva, Lucília, Santos, Maria M. M.

Source: ChemMedChem. 16(1):250-258

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Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells

Authors: Pediconi, Natalia, Ghirga, Francesca, Del Plato, Cristina, Peruzzi, Giovanna, Athanassopoulos, Constantinos M., Mori, Mattia, Crestoni, Maria Elisa, Corinti, Davide, Ugozzoli, Franco, Massera, Chiara

Source: Bioconjugate chemistry. 32(6):1105-1116

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631435644&indx=1&recIds=ETOCRN631435644