Pigment epithelium derived factor drives melanocyte proliferation and migration in neurofibromatosis café au lait macules.

Authors: Lovatt, Charlotte, Williams, Megan, Gibbs, Alex, Mukhtar, Abdullahi, Morgan, Huw J., Lanfredini, Simone, Olivero, Carlotta, Spurlock, Gill, Davies, Sally, Philpott, Charlotte, Tovell, Hannah, Turnpenny, Peter, Baban, Dilair, Knight, Sam, Brems, Hilde, Sampson, Julian R., Legius, Eric, Upadhyaya, Meena, Patel, Girish K.

Source: Skin Health & Disease; Oct2024, Vol. 4 Issue 5, p1-11, 11p

Targeting CD20-expressing malignant melanoma cells augments BRAF inhibitor killing.

Authors: Mukhtar, Abdullahi B¹ (AUTHOR), Morgan, Huw J¹ (AUTHOR), Gibbs, Alex¹ (AUTHOR), Davies, Gemma E¹ (AUTHOR), Lovatt, Charlotte¹ (AUTHOR), Patel, Girish K¹ (AUTHOR) patelgk@cardiff.ac.uk

Source: British Journal of Dermatology. May2024, Vol. 190 Issue 5, p729-739. 11p.

Subject Terms: *IPILIMUMAB, *CANCER cells, *MELANOMA, *BRAF genes, *STEM cell treatment, *FORKHEAD transcription factors

CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis.

Authors: Morgan, Huw J.¹, Rees, Elise¹, Lanfredini, imone¹, Powell, Kate A.¹, Gore, Jasmine¹, Gibbs, Alex¹, Lovatt, Charlotte¹, Davies, Gemma E.¹, Olivero, Carlotta¹, Shorning, Boris Y.¹, Tornillo, Giusy¹, Tonks, Alex², Darley, Richard², Wang, Eddie C. Y.³, Patel, Girish K.¹ patelgk@cardiff.ac.uk, Lanfredini, Simone⁴, Wang, Eddie Cy⁵

Source: Journal of Clinical Investigation. 11/1/2022, Vol. 132 Issue 21, p1-16. 16p.

O03 HPV8 leads to Lrig1+ keratinocyte stem cell expansion into the overlying epidermis.

Authors: Morgan, Huw J¹ (AUTHOR), Shorning, Boris¹ (AUTHOR), Olivero, Carlotta¹ (AUTHOR), Borgogna, Cinzia² (AUTHOR), Akgul, Baki³ (AUTHOR), Gariglio, Marisa² (AUTHOR), Patel, Girish K¹ (AUTHOR)

Source: British Journal of Dermatology. Jul2023, Vol. 189 Issue 1, pe5-e5. 1p.

Subject Terms: *STEM cells, *KERATINOCYTES, *EPIDERMIS, *HAIR follicles, *HUMAN papillomavirus, *ACTINIC keratosis

O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion.

Authors: Shorning, Boris¹ (AUTHOR), Morgan, Huw J¹ (AUTHOR), Olivero, Carlotta¹ (AUTHOR), Borgogna, Cinzia² (AUTHOR), Gariglio, Marisa² (AUTHOR), Akgul, Baki³ (AUTHOR), Patel, Girish K¹ (AUTHOR)

Source: British Journal of Dermatology. Jul2023, Vol. 189 Issue 1, pe5-e5. 1p.

Subject Terms: *STEM cells, *KERATINOCYTES, *SMALL interfering RNA, *HUMAN papillomavirus, *HAIR follicles, *ACTINIC keratosis