Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation.

Authors: Carter-Cusack, Dylan¹, david.hume@uq.edu.au, Huang, Stephen¹, Keshvari, Sahar¹, Patkar, Omkar¹, Sehgal, Anuj¹, Allavena, Rachel², Byrne, Robert A. J.³, Morgan, B. Paul³, Bush, Stephen J.⁴, Summers, Kim M.¹, Irvine, Katharine M.¹, Hume, David A.¹, d.cartercusack@student.uq.edu.au

Source: PLoS Genetics; 1/27/2025, Vol. 21 Issue 1, p1-39, 39p

Complement dysregulation is a prevalent and therapeutically amenable feature of long COVID

Authors: Baillie, Kirsten, Davies, Helen E., Keat, Samuel B.K., Ladell, Kristin, Miners, Kelly L., Jones, Samantha A., Mellou, Ermioni, Toonen, Erik J.M., Price, David A., Morgan, B. Paul, Zelek, Wioleta M.

Source: In Med 8 March 2024 5(3):239-253

Complement receptor 1 is expressed on brain cells and in the human brain

Authors: Daskoulidou, Nikoleta, Shaw, Bethany, Torvell, Megan, Watkins, Lewis, Cope, Emma L., Carpanini, Sarah M., Allen, Nicholas D., Morgan, B. Paul

Source: Glia. 71(6):1522-1535

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182091920.0x000001&indx=1&recIds=ETOCvdc_100182091920.0x000001

Complement dysregulation and Alzheimer's disease in Down syndrome

Authors: Veteleanu, Aurora, Pape, Sarah, Davies, Kate, Kodosaki, Eleftheria, Hye, Abdul, Zelek, Wioleta M., Strydom, Andre, Morgan, B. Paul

Source: Alzheimer's & dementia. 19(4):1383-1392

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179297990.0x000001&indx=1&recIds=ETOCvdc_100179297990.0x000001

Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19

Authors: Siggins, Matthew K., Davies, Kate, Fellows, Rosie, Thwaites, Ryan S., Baillie, J. Kenneth, Semple, Malcolm G., Openshaw, Peter J. M., Zelek, Wioleta M., Harris, Claire L., Morgan, B. Paul

Source: Immunology. 168(3):473-492

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176277250.0x000001&indx=1&recIds=ETOCvdc_100176277250.0x000001

Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation

Authors: Bowen, Emily E., Hurcombe, Jennifer A., Barrington, Fern, Keir, Lindsay S., Farmer, Louise K., Wherlock, Matthew D., Ortiz-Sandoval, Carolina G., Bruno, Valentina, Bohorquez-Hernandez, Arlette, Diatlov, Daniel, Rostam-Shirazi, Niyousha, Wells, Sara, Stewart, Michelle, Teboul, Lydia, Lay, Abigail C., Butler, Matthew J., Pope, Robert J.P., Larkai, Eva M.S., Morgan, B. Paul, Moppett, John, Satchell, Simon C., Welsh, Gavin I., Walker, Patrick D., Licht, Christoph, Saleem, Moin A., Coward, Richard J.M.

Source: In Med 10 November 2023 4(11):761-777

Whole blood‐based measurement of SARS‐CoV‐2‐specific T cells reveals asymptomatic infection and vaccine immunogenicity in healthy subjects and patients with solid‐organ cancers

Authors: Scurr, Martin J., Zelek, Wioleta M., Lippiatt, George, Somerville, Michelle, Burnell, Stephanie E. A., Capitani, Lorenzo, Davies, Kate, Lawton, Helen, Tozer, Thomas, Rees, Tara, Roberts, Kerry, Evans, Mererid, Jackson, Amanda, Young, Charlotte, Fairclough, Lucy, Tighe, Paddy, Wills, Mark, Westwell, Andrew D., Morgan, B. Paul, Gallimore, Awen, Godkin, Andrew

Source: Immunology. 165(2):250-259

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138910491.0x000001&indx=1&recIds=ETOCvdc_100138910491.0x000001

Targeting complement in neurodegeneration: challenges, risks, and strategies

Authors: Zelek, Wioleta M., Morgan, B. Paul

Source: Trends in pharmacological sciences. 43(8):615-628

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167399871.0x000001&indx=1&recIds=ETOCvdc_100167399871.0x000001

Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder

Authors: Westacott, Laura J., Humby, Trevor, Haan, Niels, Brain, Sophie A., Bush, Emma-Louise, Toneva, Margarita, Baloc, Andreea-Ingrid, Moon, Anna L., Reddaway, Jack, Owen, Michael J., Hall, Jeremy, Hughes, Timothy R., Morgan, B. Paul, Gray, William P., Wilkinson, Lawrence S.

Source: Brain behavior and immunity. 99:70-82

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162685451.0x000001&indx=1&recIds=ETOCvdc_100162685451.0x000001

Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features

Authors: Banda, Nirmal K., Deane, Kevin D., Bemis, Elizabeth A., Strickland, Colin, Seifert, Jennifer, Jordan, Kimberly, Goldman, Katriona, Morgan, B. Paul, Moreland, Larry W., Lewis, Myles J.

Source: Journal of immunology. 208(11):2482-2496

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629412371&indx=1&recIds=ETOCRN629412371

Dissociable effects of complement C3 and C3aR on survival and morphology of adult born hippocampal neurons, pattern separation, and cognitive flexibility in male mice

Authors: Westacott, Laura J., Haan, Niels, Evison, Claudia, Marei, Omar, Hall, Jeremy, Hughes, Timothy R., Zaben, Malik, Morgan, B. Paul, Humby, Trevor, Wilkinson, Lawrence S., Gray, William P.

Source: In Brain Behavior and Immunity November 2021 98:136-150

Peripheral immune markers and antipsychotic non-response in psychosis

Authors: Enache, Daniela, Nikkheslat, Naghmeh, Fathalla, Dina, Morgan, B. Paul, Lewis, Shôn, Drake, Richard, Deakin, Bill, Walters, James, Lawrie, Stephen M., Egerton, Alice, MacCabe, James H., Mondelli, Valeria

Source: In Schizophrenia Research April 2021 230:1-8

Sepsis target validation for repurposing and combining complement and immune checkpoint inhibition therapeutics

Authors: Rodrigues, Patrícia R.S., Picco, Noemi, Morgan, B Paul, Ghazal, Peter

Source: Expert opinion on drug discovery. 16(5):537-551

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100124228831.0x000001&indx=1&recIds=ETOCvdc_100124228831.0x000001

C3 Glomerulopathy and Related Disorders in Children

Authors: Wong, Edwin K.S., Marchbank, Kevin J., Lomax-Browne, Hannah, Pappworth, Isabel Y., Denton, Harriet, Cooke, Katie, Ward, Sophie, McLoughlin, Amy-Claire, Richardson, Grant, Wilson, Valerie, Harris, Claire L., Morgan, B. Paul, Hakobyan, Svetlana, McAlinden, Paul, Gale, Daniel P., Maxwell, Heather, Christian, Martin, Malcomson, Roger, Goodship, Timothy H.J., Marks, Stephen D., Pickering, Matthew C., Kavanagh, David, Cook, H. Terence, Johnson, Sally A.

Source: Clinical journal of the American Society of Nephrology. 16(11):1639-1651

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192341134.0x000001&indx=1&recIds=ETOCvdc_100192341134.0x000001

Role of the Complement Pathway in Inflammatory Skin Diseases: A Focus on Hidradenitis Suppurativa

Authors: Ghias, Mondana H., Hyde, Michael J., Tomalin, Lewis E., Morgan, B. Paul, Alavi, Afsaneh, Lowes, Michelle A., Piguet, Vincent

Source: In Journal of Investigative Dermatology March 2020 140(3):531-536

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Authors: Shi, Liu, Westwood, Sarah, Baird, Alison L., Winchester, Laura, Dobricic, Valerija, Kilpert, Fabian, Hong, Shengjun, Franke, Andre, Hye, Abdul, Ashton, Nicholas J., Morgan, Angharad R., Bos, Isabelle, Vos, Stephanie J.B., Buckley, Noel J., Kate, Mara ten, Scheltens, Philip, Vandenberghe, Rik, Gabel, Silvy, Meersmans, Karen, Engelborghs, Sebastiaan, De Roeck, Ellen E., Sleegers, Kristel, Frisoni, Giovanni B., Blin, Olivier, Richardson, Jill C., Bordet, Régis, Molinuevo, José L., Rami, Lorena, Wallin, Anders, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans, Lleó, Alberto, Alcolea, Daniel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Johannsen, Peter, Teunissen, Charlotte E., Freund-Levi, Yvonne, Frölich, Lutz, Legido-Quigley, Cristina, Barkhof, Frederik, Blennow, Kaj, Zetterberg, Henrik, Baker, Susan, Morgan, B. Paul, Streffer, Johannes, Visser, Pieter Jelle, Bertram, Lars, Lovestone, Simon, Nevado-Holgado, Alejo J.

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association November 2019 15(11):1478-1488

Compendium of current complement therapeutics

Authors: Zelek, Wioleta M, Xie, Long, Morgan, B Paul, Harris, Claire L

Source: In Molecular Immunology October 2019 114:341-352

Inflammatory biomarkers in Alzheimer's disease plasma

Authors: Bullmore, Edward T., Bhatti, Junaid, Chamberlain, Samuel J., Correia, Marta M., Crofts, Anna L., Dickinson, Amber, Foster, Andrew C., Kitzbichler, Manfred G., Knight, Clare, Lynall, Mary-Ellen, Maurice, Christina, O'Donnell, Ciara, Pointon, Linda J., St George Hyslop, Peter, Turner, Lorinda, Vertes, Petra, Widmer, Barry, Williams, Guy B., Morgan, B. Paul, Leckey, Claire A., Morgan, Angharad R., O'Hagan, Caroline, Touchard, Samuel, Cavanagh, Jonathan, Deith, Catherine, Farmer, Scott, McClean, John, McColl, Alison, McPherson, Andrew, Scouller, Paul, Sutherland, Murray, Boddeke, H.W.G.M., Richardson, Jill C., Khan, Shahid, Murphy, Phil, Parker, Christine A., Patel, Jai, Jones, Declan, de Boer, Peter, Kemp, John, Drevets, Wayne C., Nye, Jeffrey S., Wittenberg, Gayle, Isaac, John, Bhattacharya, Anindya, Carruthers, Nick, Kolb, Hartmuth, Pariante, Carmine M., Turkheimer, Federico, Barker, Gareth J., Byrom, Heidi, Cash, Diana, Cattaneo, Annamaria, Gee, Antony, Hastings, Caitlin, Mariani, Nicole, McLaughlin, Anna, Mondelli, Valeria, Nettis, Maria, Nikkheslat, Naghmeh, Randall, Karen, Sheridan, Hannah, Simmons, Camilla, Singh, Nisha, Van Loo, Victoria, Vicente-Rodriguez, Marta, Wood, Tobias C., Worrell, Courtney, Zajkowska, Zuzanna, Plath, Niels, Egebjerg, Jan, Eriksson, Hans, Gastambide, Francois, Adams, Karen Husted, Jeggo, Ross, Thomsen, Christian, Pederson, Jan Torleif, Campbell, Brian, Möller, Thomas, Nelson, Bob, Zorn, Stevin, O'Connor, Jason, Attenburrow, Mary Jane, Baird, Alison, Benjamin, Jithen, Clare, Stuart, Cowen, Philip, Huang, I-Shu (Dante), Hurley, Samuel, Jones, Helen, Lovestone, Simon, Mada, Francisca, Nevado-Holgado, Alejo, Oladejo, Akintayo, Ribe, Elena, Smith, Katy, Vyas, Anviti, Hughes, Zoe, Balice-Gordon, Rita, Duerr, James, Piro, Justin R., Sporn, Jonathan, Perry, V. Hugh, Cleal, Madeleine, Fryatt, Gemma, Gomez-Nicola, Diego, Mancuso, Renzo, Reynolds, Richard, Harrison, Neil A., Cercignani, Mara, Clarke, Charlotte L., Hoskins, Elizabeth, Kohn, Charmaine, Murray, Rosemary, Wilcock, Lauren, Wlazly, Dominika, Mount, Howard, Leckey, Claire, Nevado-Holgado, Alejo J., Barkhof, Frederik, Bertram, Lars, Blin, Olivier, Bos, Isabelle, Dobricic, Valerija, Engelborghs, Sebastiaan, Frisoni, Giovanni, Frölich, Lutz, Gabel, Silvey, Johannsen, Peter, Kettunen, Petronella, Kłoszewska, Iwona, Legido-Quigley, Cristina, Lleó, Alberto, Martinez-Lage, Pablo, Mecocci, Patrizia, Meersmans, Karen, Molinuevo, José Luis, Peyratout, Gwendoline, Popp, Julius, Richardson, Jill, Sala, Isabel, Scheltens, Philip, Streffer, Johannes, Soininen, Hikka, Tainta-Cuezva, Mikel, Teunissen, Charlotte, Tsolaki, Magda, Vandenberghe, Rik, Visser, Pieter Jelle, Vos, Stephanie, Wahlund, Lars-Olof, Wallin, Anders, Westwood, Sarah, Zetterberg, Henrik

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association June 2019 15(6):776-787

Research priorities for the COVID‐19 pandemic and beyond: A call to action for psychological science

Authors: O'Connor, Daryl B., Aggleton, John P., Chakrabarti, Bhismadev, Cooper, Cary L., Creswell, Cathy, Dunsmuir, Sandra, Fiske, Susan T., Gathercole, Susan, Gough, Brendan, Ireland, Jane L., Jones, Marc V., Jowett, Adam, Kagan, Carolyn, Karanika‐Murray, Maria, Kaye, Linda K., Kumari, Veena, Lewandowsky, Stephan, Lightman, Stafford, Malpass, Debra, Meins, Elizabeth, Morgan, B. Paul, Morrison Coulthard, Lisa J., Reicher, Stephen D., Schacter, Daniel L., Sherman, Susan M., Simms, Victoria, Williams, Antony, Wykes, Til, Armitage, Christopher J.

Source: British journal of psychology. 111(4):603-629

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108238710.0x000001&indx=1&recIds=ETOCvdc_100108238710.0x000001

Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage

Authors: van Dijk, Bart J., Meijers, Joost C.M., Kloek, Anne T., Knaup, Veronique L., Rinkel, Gabriel J.E., Morgan, B. Paul, van der Kamp, Marije J., Osuka, Koji, Aronica, Eleonora, Ruigrok, Ynte M., van de Beek, Diederik, Brouwer, Matthijs, Pekna, Marcela, Hol, Elly M., Vergouwen, Mervyn D.I.

Source: Translational stroke research. 11(4):678-688

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171884316.0x000001&indx=1&recIds=ETOCvdc_100171884316.0x000001