Breadth of immune response, immunogenicity, reactogenicity, and safety for a pentavalent meningococcal ABCWY vaccine in healthy adolescents and young adults: results from a phase 3, randomised, controlled observer-blinded trial

Authors: Bloch, Mark, Richmond, Peter, Athan, Eugene, Nolan, Terry, Dalebout, Marije, Tiong, Florence, de Looze, Ferdinandus, Dinleyici, Ener Cagri, Ince, Tolga, Cetin, Benhur, Ulukol, Betul, Beran, Jiří, Dražan, Daniel, Adamovska, Renata, Spaziererova, Martina, Zemanek, Josef, Pavlasek, Miroslav, Meisalu, Sandra, Kiiroja, Kaia, Rämet, Mika, Seppä, Ilkka, Koski, Susanna, Ukkonen, Benita, Kokko, Satu, Laajalahti, Outi, Paavola, Pauliina, Dionne, Marc, Gupta, Anil, Langley, Joanne, Kellner, James, Tapiero, Bruce, Vale, Noah, Vachon, Marie-Louise, Sadarangani, Manish, Dzongowski, Peter, Tipton, Mary, Rok, Walter, Schear, Martin, Simon, William, Staben, Jonathan, Grubb, Paul, Jeanfreau, Robert, Pelayo, Enrique, Patel, Minesh, Rouhbakhsh, Rambod, Silas, Peter, Finn, Daniel, Surber, Joseph, Freeman, George, Chakerian, Maia, Osowa, Alexander, Ayesu, Kwabena, Jones, Jake, Gottfredson, Ryan, Scott, John, Byars, William, Mehta, Hemalini, Carter, Robert, Farjo, Rand, Ackerman, Ronald, Bernard, David, Sanchez, Yamirka, Lattanzi, Maria, Trapani, Mauro, Bhusal, Chiranjiwi, Toneatto, Daniela, Willemsen, Arnold, Lechevin, Isabelle, Raulier, Stefanie, Wauters, Dominique, Morelle, Danielle, Cetin, Benhur Sirvan ^f, Langley, Joanne M ^l, Richmond, Peter C ⁿ

Source: In The Lancet Infectious Diseases May 2025 25(5):560-573

Efficacy of RTS,S/AS01E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5–17 months in Ghana and Kenya: an open-label, phase 2b, randomised controlled trial

Authors: Sambian, David, Agordo Dornudo, Albert, Nana Badu, Lydia, Akoi, Kwame, Antwi, Evans, Onoka, Kelvin, K'Orimba, Kevin, Ndaya Oloo, Paul, Leakey, Elizabeth, Gvozdenovic, Emilia, Cravcenco, Cristina, Vandoolaeghe, Pascale, Vekemans, Johan, Ivinson, Karen, Samuels, Aaron M ^*, Ansong, Daniel, Kariuki, Simon K, Adjei, Samuel, Bollaerts, Anne, Ockenhouse, Christian, Westercamp, Nelli, Lee, Cynthia K, Schuerman, Lode, Bii, Dennis K, Osei-Tutu, Lawrence, Oneko, Martina, Lievens, Marc, Attobrah Sarfo, Maame Anima, Atieno, Cecilia, Morelle, Danielle, Bakari, Ashura, Sang, Tony, Jongert, Erik, Kotoh-Mortty, Maame Fremah, Otieno, Kephas, Roman, François, Buabeng, Patrick Boakye Yiadom, Ntiamoah, Yaw, Ofori-Anyinam, Opokua ^*, Agbenyega, Tsiri ^*

Source: In The Lancet Infectious Diseases September 2022 22(9):1329-1342

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01 B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP

Authors: Rampling, Tommy, Ewer, Katie J., Bowyer, Georgina, Bliss, Carly M., Edwards, Nick J., Wright, Danny, Payne, Ruth O., Venkatraman, Navin, de Barra, Eoghan, Snudden, Claudia M., Poulton, Ian D., de Graaf, Hans, Sukhtankar, Priya, Roberts, Rachel, Ivinson, Karen, Weltzin, Rich, Rajkumar, Bebi-Yassin, Wille-Reece, Ulrike, Lee, Cynthia K., Ockenhouse, Christian F., Sinden, Robert E., Gerry, Stephen, Lawrie, Alison M., Vekemans, Johan, Morelle, Danielle, Lievens, Marc, Ballou, Ripley W., Cooke, Graham S., Faust, Saul N., Gilbert, Sarah, Hill, Adrian V. S.

Source: The Journal of Infectious Diseases, 2016 Sep 01. 214(5), 772-781.

Access URL: http://www.jstor.org/stable/44007148

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

Authors: Regules, Jason A., Cicatelli, Susan B., Bennett, Jason W., Paolino, Kristopher M., Twomey, Patrick S., Moon, James E., Kathcart, April K., Hauns, Kevin D., Komisar, Jack L., Qabar, Aziz N., Davidson, Silas A., Dutta, Sheetij, Griffith, Matthew E., Magee, Charles D., Wojnarski, Mariusz, Livezey, Jeffrey R., Kress, Adrian T., Waterman, Paige E., Jongert, Erik, Wille-Reece, Ulrike, Volkmuth, Wayne, Emerling, Daniel, Robinson, William H., Lievens, Marc, Morelle, Danielle, Lee, Cynthia K., Yassin-Rajkumar, Bebi, Weltzin, Richard, Cohen, Joe, Paris, Robert M., Waters, Norman C., Birkett, Ashley J., Kaslow, David C., Ballou, W. Ripley, Ockenhouse, Christian F., Vekemans, Johan

Source: The Journal of Infectious Diseases, 2016 Sep 01. 214(5), 762-771.

Access URL: http://www.jstor.org/stable/44007147

Local tolerance and systemic toxicity of single and repeated intramuscular administrations of two different formulations of the RTS,S malaria candidate vaccine in rabbits

Authors: Segal, Lawrence, Morelle, Danielle, Blee, Mark, Moore, Emma, Damsten, Micaela, Liu, Kai Chiu, Destexhe, Eric, Garçon, Nathalie

Source: In Regulatory Toxicology and Pharmacology March 2015 71(2):269-278

A Phase IIa Controlled Human Malaria Infection and Immunogenicity Study of RTS,S/AS01E and RTS,S/AS01B Delayed Fractional Dose Regimens in Malaria-Naive Adults.

Authors: Moon, James E, Ockenhouse, Christian, Regules, Jason A, Vekemans, Johan, Lee, Cynthia, Chuang, Ilin, Traskine, Magali, Jongert, Erik, Ivinson, Karen, Morelle, Danielle, Komisar, Jack L, Lievens, Marc, Sedegah, Martha, Garver, Lindsey S, Sikaffy, April K, Waters, Norman C, Ballou, William Ripley, Ofori-Anyinam, Opokua, RTS, RTS,S Malaria Vaccine Working Group

Source: Journal of Infectious Diseases; 11/15/2020, Vol. 222 Issue 10, p1681-1691, 11p

Subject Terms: MALARIA, VACCINE trials, VACCINE effectiveness, ADULTS, CONTROLLED release preparations, MALARIA prevention, PROTOZOA, RESEARCH, VACCINES, IMMUNIZATION, PREVENTION of communicable diseases, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, MEDICAL protocols, COMPARATIVE studies, RANDOMIZED controlled trials

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

CXCR3⁺ T Follicular Helper Cells Induced by Co-Administration of RTS,S/AS01B and Viral-Vectored Vaccines Are Associated With Reduced Immunogenicity and Efficacy Against Malaria.

Authors: Bowyer, Georgina, Grobbelaar, Amy, Rampling, Tommy, Venkatraman, Navin, Morelle, Danielle, Ballou, Ripley W., Hill, Adrian V. S., Ewer, Katie J.

Source: Frontiers in Immunology; 7/25/2018, pN.PAG-N.PAG, 15p

Subject Terms: T helper cells, MALARIA vaccines, MALARIA immunology

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.