Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells

Authors: Azevedo‐Pouly, Ana C, Appell, Lauren E, Burdine, Lyle, Rogers, Lora J, Morehead, Lauren C, Fil, Daniel, Barker, Melanie, Rainwater, Randall R, Waldrip, Zachary J, Koss, Brian, Burdine, Marie Schluterman

Source: Immunology and cell biology. 101(7):663-671

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189965499.0x000001&indx=1&recIds=ETOCvdc_100189965499.0x000001

Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model.

Authors: Morehead, Lauren C.¹ (AUTHOR) gargsarita@uams.edu, Garg, Sarita¹ (AUTHOR) ajtackett@uams.edu, Wallis, Katherine F.¹ (AUTHOR), Simoes, Camila C.² (AUTHOR) ccsimoes@uams.edu, Siegel, Eric R.³ (AUTHOR), Tackett, Alan J.¹ (AUTHOR), Miousse, Isabelle R.¹ (AUTHOR) iracinemiousse@uams.edu

Source: Cancers. Sep2023, Vol. 15 Issue 18, p4467. 16p.

Subject Terms: *DIET in disease, *IN vitro studies, *PROTEINS, *IMMUNE checkpoint inhibitors, *IN vivo studies, *ANIMAL experimentation, *METHIONINE, *CELL receptors, *DIET therapy, *COLORECTAL cancer, *GENE expression, *INTERFERONS, *CELLULAR signal transduction, *SEX distribution, *RESEARCH funding, *COMBINED modality therapy, *MICE

Differences in cell death in methionine versus cysteine depletion

Authors: Wallis, Katherine F., Morehead, Lauren C., Bird, Jordan T., Byrum, Stephanie D., Miousse, Isabelle R.

Source: Environmental and molecular mutagenesis. 62(3):216-226

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116438059.0x000001&indx=1&recIds=ETOCvdc_100116438059.0x000001

Impact of the Society for Pediatric Dermatology Mentorship Award Program on Careers in Pediatric Dermatology: Workforce Implications.

Authors: Morehead, Lauren C.¹ (AUTHOR), Duffy, Emily K.^2,3 (AUTHOR), Boos, Markus D.^2,3 (AUTHOR) markus.boos@seattlechildrens.org

Source: Pediatric Dermatology. Nov2024, p1. 4p.

Subject Terms: *PEDIATRIC dermatology, *PATIENTS' attitudes, *MENTORING, *LABOR supply, *ENTERTAINING

The evolving clinical landscape for dendritic cell vaccines and cancer immunotherapy

Authors: Cannon, Martin J, Block, Matthew S, Morehead, Lauren C, Knutson, Keith L

Source: Immunotherapy. 11(2):75-79

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188378337.0x000001&indx=1&recIds=ETOCvdc_100188378337.0x000001

Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma

Authors: Morehead, Lauren C., Koss, Brian, Fil, Daniel, Heflin, Billie, Garg, Sarita, Wallis, Katherine F., Tackett, Alan J., Miousse, Isabelle R.

Source: In Molecular Immunology November 2023 163:188-195

Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4⁺ helper and CD8⁺ effector T cells.

Authors: Azevedo‐Pouly, Ana C, Appell, Lauren E, Burdine, Lyle, Rogers, Lora J, Morehead, Lauren C, Fil, Daniel, Barker, Melanie, Rainwater, Randall R, Waldrip, Zachary J, Koss, Brian, Burdine, Marie Schluterman

Source: Immunology & Cell Biology; Aug2023, Vol. 101 Issue 7, p663-671, 9p

Subject Terms: T cells, T cell receptors, T helper cells, PROTEOMICS, GRAFT rejection, PROTEIN kinases