LLDAS and remission attainment with anifrolumab treatment in patients with systemic lupus erythematosus: results from the TULIP and long-term extension randomised controlled trials

Authors: Morand, Eric F. ¹, van Vollenhoven, Ronald ², Furie, Richard A. ³, Kalunian, Kenneth C. ⁴, Manzi, Susan ⁵, Abreu, Gabriel ⁶, Tummala, Raj ^{7, †}, Duncan, Elizabeth A. ^{7, †}, Al-Mossawi, Hussein ^{8, †}, Lindholm, Catharina ^{6, ⁎}

Source: In Annals of the Rheumatic Diseases November 2024

Systemic lupus erythematosus in Aboriginal and Torres Strait Islander peoples in Australia: addressing disparities and barriers to optimising patient care

Authors: Eades, Laura E, Hoi, Alberta Y, Liddle, Ruaidhri, Sines, Jason, Kandane-Rathnayake, Rangi, Khetan, Sachin, Nossent, Johannes, Lindenmayer, Greta, Morand, Eric F, Liew, David F L, Rischmueller, Maureen, Brady, Stephen, Brown, Alex, Vincent, Fabien B ^*

Source: In The Lancet Rheumatology October 2024 6(10):e713-e726

Association of sustained lupus low disease activity state with improved outcomes in systemic lupus erythematosus: a multinational prospective cohort study

Authors: Golder, Vera ^*, Kandane-Rathnayake, Rangi, Li, Ning, Louthrenoo, Worawit, Chen, Yi-Hsing, Cho, Jiacai, Lateef, Aisha, Hamijoyo, Laniyati, Luo, Shue Fen, Wu, Yeong-Jian, Navarra, Sandra V, Zamora, Leonid, Li, Zhanguo, Sockalingam, Sargunan, Katsumata, Yasuhiro, Harigai, Masayoshi, Hao, Yanjie, Zhang, Zhuoli, Basnayake, Duminda, Chan, Madelynn, Kikuchi, Jun, Takeuchi, Tsutomu, Bae, Sang-Cheol, Goldblatt, Fiona, Oon, Shereen, O'Neill, Sean, Ng, Kristine, Law, Annie, Tugnet, Nicola, Kumar, Sunil, Tee, Cherica, Tee, Michael, Ohkubo, Naoaki, Tanaka, Yoshiya, Lau, Chak Sing, Hoi, Alberta, Nikpour, Mandana, Morand, Eric F

Source: In The Lancet Rheumatology August 2024 6(8):e528-e536

Autoimmune rheumatic disease in Australian Aboriginal and Torres Strait Islander Peoples: What do we know?

Authors: Eades, Laura E, Sines, Jason, Hoi, Alberta Y, Liddle, Ruaidhri, Kandane-Rathnayake, Rangi, Morand, Eric F, Brady, Stephen, Rischmueller, Maureen, Vincent, Fabien B

Source: In Seminars in Arthritis and Rheumatism April 2024 65

Preclinical Evidence for the Glucocorticoid-Sparing Potential of a Dual Toll-Like Receptor 7/8 Inhibitor in Autoimmune Diseases

Authors: Deshmukh, Ankita, Pereira, Albertina, Geraci, Nicholas, Tzvetkov, Evgeni, Przetak, Melinda, Catalina, Michelle D., Morand, Eric F., Bender, Andrew T., Vaidyanathan, Bharat ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics March 2024 388(3):751-764

Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 3 trial (SLE-BRAVE-I)

Authors: Morand, Eric F, Vital, Edward M, Petri, Michelle, van Vollenhoven, Ronald, Wallace, Daniel J, Mosca, Marta, Furie, Richard A, Silk, Maria E, Dickson, Christina L, Meszaros, Gabriella, Jia, Bochao, Crowe, Brenda, de la Torre, Inmaculada, Dörner, Thomas

Source: Lancet. 401(10381):1001-1010

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189650943.0x000001&indx=1&recIds=ETOCvdc_100189650943.0x000001

Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 3 trial (SLE-BRAVE-II)

Authors: Petri, Michelle, Bruce, Ian N, Dörner, Thomas, Tanaka, Yoshiya, Morand, Eric F, Kalunian, Kenneth C, Cardiel, Mario H, Silk, Maria E, Dickson, Christina L, Meszaros, Gabriella, Zhang, Lu, Jia, Bochao, Zhao, Youna, McVeigh, Conor J, Mosca, Marta

Source: Lancet. 401(10381):1011-1019

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186853746.0x000001&indx=1&recIds=ETOCvdc_100186853746.0x000001

Association of Modified Systemic Lupus Erythematosus Responder Index Attainment With Long‐Term Clinical Outcomes: A Five‐Year Prospective Study

Authors: Connelly, Kathryn, Kandane‐Rathnayake, Rangi, Hoi, Alberta, Louthrenoo, Worawit, Hamijoyo, Laniyati, Luo, Shue Fen, Wu, Yeong‐Jian Jan, Cho, Jiacai, Lateef, Aisha, Lau, CS, Chen, Yi‐Hsing, Navarra, Sandra, Zamora, Leonid, Li, Zhanguo, An, Yuan, Sockalingam, Sargunan, Hao, Yanjie, Zhang, Zhuoli, Chan, Madelynn, Katsumata, Yasuhiro, Harigai, Masayoshi, Oon, Shereen, Bae, Sang‐Cheol, O'Neill, Sean, Gibson, Kathryn A., Basnayake, BMDB, Kikuchi, Jun, Takeuchi, Tsutomu, Ng, Kristine Pek Ling, Tugnet, Nicola, Kumar, Sunil, Goldblatt, Fiona, Law, Annie, Tee, Michael, Tee, Cherica, Tanaka, Yoshiya, Ohkubo, Naoaki, Tan, Jin Yu, Karyekar, Chetan S., Nikpour, Mandana, Golder, Vera, Morand, Eric F.

Source: Arthritis & rheumatology. 75(3):401-410

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185305935.0x000001&indx=1&recIds=ETOCvdc_100185305935.0x000001

A Randomized, Placebo‐Controlled Phase III Extension Trial of the Long‐Term Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythematosus

Authors: Kalunian, Kenneth C., Furie, Richard, Morand, Eric F., Bruce, Ian N., Manzi, Susan, Tanaka, Yoshiya, Winthrop, Kevin, Hupka, Ihor, Zhang, Lijin (Jinny), Werther, Shanti, Abreu, Gabriel, Hultquist, Micki, Tummala, Raj, Lindholm, Catharina, Al‐Mossawi, Hussein

Source: Arthritis & rheumatology. 75(2):253-265

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184974708.0x000001&indx=1&recIds=ETOCvdc_100184974708.0x000001

Evaluating the Construct of Damage in Systemic Lupus Erythematosus

Authors: Johnson, Sindhu R., Gladman, Dafna D., Brunner, Hermine I., Isenberg, David, Clarke, Ann E., Barber, Megan R. W., Arnaud, Laurent, Fortin, Paul R., Mosca, Marta, Voskuyl, Alexandre E., Manzi, Susan, Aranow, Cynthia, Askanase, Anca, Alarcón, Graciela S., Bae, Sang‐Cheol, Costedoat‐Chalumeau, Nathalie, English, Jessica A., Pons‐Estel, Guillermo J., Pons‐Estel, Bernardo A., Gilman, Rebecca, Ginzler, Ellen M., Hanly, John G., Jacobsen, Soren, Kalunian, Kenneth, Kamen, Diane L., Lambalgen, Chynace, Legge, Alexandra, Lim, S. Sam, Mak, Anselm, Morand, Eric F., Peschken, Christine A., Petri, Michelle, Rahman, Anisur, Ramsey‐Goldman, Rosalind, Reynolds, John A., Romero‐Diaz, Juanita, Ruiz‐Irastorza, Guillermo, Sanchez‐Guerrero, Jorge, Svenungsson, Elisabet, Touma, Zahi, Urowitz, Murray, Vinet, Evelyne, Vollenhoven, Ronald F., Waldhauser, Heather, Wallace, Daniel J., Zoma, Asad, Bruce, Ian N.

Source: Arthritis care & research. 75(5):998-1006

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181407921.0x000001&indx=1&recIds=ETOCvdc_100181407921.0x000001

Impact of low disease activity, remission, and complete remission on flares following tapering of corticosteroids and immunosuppressive therapy in patients with systemic lupus erythematous: a multinational cohort study

Authors: Cho, Jiacai ^*, Shen, Liang, Huq, Molla, Kandane-Rathnayake, Rangi, Golder, Vera, Louthrenoo, Worawit, Chen, Yi-Hsing, Hamijoyo, Laniyati, Luo, Shue-Fen, Wu, Yeong-Jian J, Zamora, Leonid, Li, Zhanguo, Sockalingam, Sargunan, Katsumata, Yasuhiro, Harigai, Masayoshi, Hao, Yanjie, Zhang, Zhuoli, Basnayake, Duminda, Chan, Madelynn, Kikuchi, Jun, Takeuchi, Tsutomu, Bae, Sang-Cheol, Oon, Shereen, O'Neill, Sean, Goldblatt, Fiona, Ng, Kristine Pek Ling, Law, Annie, Tugnet, Nicola, Kumar, Sunil, Tee, Cherica, Tee, Michael, Ohkubo, Naoaki, Tanaka, Yoshiya, Navarra, Sandra V, Lau, Chak Sing, Hoi, Alberta, Morand, Eric F, Nikpour, Mandana, Lateef, Aisha

Source: In The Lancet Rheumatology October 2023 5(10):e584-e593

Associations of improvement in laboratory tests with clinical outcomes in patients with active systemic lupus erythematosus: a multinational longitudinal cohort study

Authors: Connelly, Kathryn ^*, Kandane-Rathnayake, Rangi, Hoi, Alberta, Louthrenoo, Worawit, Hamijoyo, Laniyati, Cho, Jiacai, Lateef, Aisha, Fen Luo, Shue, Wu, Yeong-Jian J, Li, Zhanguo, Navarra, Sandra, Zamora, Leonid, Sockalingam, Sargunan, Hao, Yanjie, Zhang, Zhuoli, Katsumata, Yasuhiro, Harigai, Masayoshi, Oon, Shereen, Chan, Madelynn, Chen, Yi-Hsing, Bae, Sang-Cheol, O'Neill, Sean, Goldblatt, Fiona, Kikuchi, Jun, Takeuchi, Tsutomu, Ling Ng, Kristine Pek, Tugnet, Nicola, Basnayake, B M D B, Ohkubo, Naoaki, Tanaka, Yoshiya, Sing Lau, Chak, Nikpour, Mandana, Golder, Vera, Morand, Eric F

Source: In The Lancet Rheumatology December 2022 4(12):e831-e841

Lupus low disease activity state and remission and risk of mortality in patients with systemic lupus erythematosus: a prospective, multinational, longitudinal cohort study

Authors: Kandane-Rathnayake, Rangi, Golder, Vera, Louthrenoo, Worawit, Chen, Yi-Hsing, Cho, Jiacai, Lateef, Aisha, Hamijoyo, Laniyati, Luo, Shue-Fen, Wu, Yeong-Jian J, Navarra, Sandra V, Zamora, Leonid, Li, Zhanguo, Sockalingam, Sargunan, Katsumata, Yasuhiro, Harigai, Masayoshi, Hao, Yanjie, Zhang, Zhuoli, Basnayake, B M D B, Chan, Madelynn, Kikuchi, Jun, Takeuchi, Tsutomu, Bae, Sang-Cheol, Oon, Shereen, O'Neill, Sean, Goldblatt, Fiona, Ng, Kristine Pek Ling, Law, Annie, Tugnet, Nicola, Kumar, Sunil, Tee, Cherica, Tee, Michael, Ohkubo, Naoaki, Tanaka, Yoshiya, Yu, DaeYoung, Karyekar, Chetan S, Sing Lau, Chak, Monk, Julie A, Nikpour, Mandana, Hoi, Alberta, Morand, Eric F ^*

Source: In The Lancet Rheumatology December 2022 4(12):e822-e830

Patterns of Medication Use in Systemic Lupus Erythematosus: A Multicenter Cohort Study

Authors: Kandane‐Rathnayake, Rangi, Louthrenoo, Worawit, Luo, Shue‐Fen, Wu, Yeong‐Jian J., Chen, Yi‐Hsing, Golder, Vera, Lateef, Aisha, Cho, Jiacai, Navarra, Sandra V., Zamora, Leonid, Hamijoyo, Laniyati, Sockalingam, Sargunan, An, Yuan, Li, Zhanguo, Montes, Ricardo, Oon, Shereen, Katsumata, Yasuhiro, Harigai, Masayoshi, Hao, Yanjie, Zhang, Zhuoli, Chan, Madelynn, Kikuchi, Jun, Takeuchi, Tsutomu, Goldblatt, Fiona, O'Neill, Sean, Bae, Sang‐Cheol, Lau, Chak S., Hoi, Alberta, Karyekar, Chetan S., Nikpour, Mandana, Morand, Eric F.

Source: Arthritis care & research. 74(12):2033-2041

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175440564.0x000001&indx=1&recIds=ETOCvdc_100175440564.0x000001

Relationship of anifrolumab pharmacokinetics with efficacy and safety in patients with systemic lupus erythematosus

Authors: Chia, Yen Lin, Zhang, Jianchun, Tummala, Raj, Rouse, Tomas, Furie, Richard A, Morand, Eric F

Source: Rheumatology. 61(5):1900-1910

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155638366.0x000001&indx=1&recIds=ETOCvdc_100155638366.0x000001

Investigating immunoregulatory effects of myeloid cell autophagy in acute and chronic inflammation

Authors: Hasnat, Md Abul, Cheang, IanIan, Dankers, Wendy, Lee, Jacinta PW, Truong, Lynda M, Pervin, Mehnaz, Jones, Sarah A, Morand, Eric F, Ooi, Joshua D, Harris, James

Source: Immunology and cell biology. 100(8):605-623

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159567759.0x000001&indx=1&recIds=ETOCvdc_100159567759.0x000001

Measurement of specific organ domains in lupus randomized controlled trials: a scoping review

Authors: Connelly, Kathryn, Vettivel, Jeevan, Golder, Vera, Kandane-Rathnayake, Rangi, Morand, Eric F

Source: Rheumatology. 61(4):1341-1353

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100146643733.0x000001&indx=1&recIds=ETOCvdc_100146643733.0x000001

Relationship Between Anifrolumab Pharmacokinetics, Pharmacodynamics, and Efficacy in Patients With Moderate to Severe Systemic Lupus Erythematosus

Authors: Chia, Yen Lin, Tummala, Raj, Mai, Tu H., Rouse, Tomas, Streicher, Katie, White, Wendy I., Morand, Eric F., Furie, Richard A.

Source: Journal of clinical pharmacology. 62(9):1094-1105

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156729260.0x000001&indx=1&recIds=ETOCvdc_100156729260.0x000001

GILZ regulates type I interferon release and sequesters STAT1

Authors: Nataraja, Champa, Flynn, Jacqueline, Dankers, Wendy, Northcott, Melissa, Zhu, Wendy, Sherlock, Rochelle, Bennett, Taylah J., Russ, Brendan E., Miceli, Iolanda, Pervin, Mehnaz, D'Cruz, Akshay, Harris, James, Morand, Eric F., Jones, Sarah A.

Source: In Journal of Autoimmunity July 2022 131

Physician Global Assessment International Standardisation COnsensus in Systemic Lupus Erythematosus: the PISCOS study

Authors: Appenzeller, Simone, Aranow, Cynthia, Askanase, Anca, Avcin, Tadej, Bae, Sang-Cheol, Bertsias, George, Bonfa, Eloisa, Cairoli, Ernesto, Cardiel, Mario H, Cervera, Ricard, Chasset, François, Chizzolini, Carlo, Clarke, Ann E, Conti, Fabrizio, Costedoat-Chalumeau, Nathalie, Czirják, László, Doria, Andrea, Dörner, Thomas, Espinosa, Gerard, Fischer-Betz, Rebecca, Garcìa, Mercedes, Gladman, Dafna D, González, Luis A, Gunnarsson, Iva, Hamijoyo, Laniyati, Hanly, John G, Hasni, Sarfaraz A, Houssiau, Frédéric A, Inanç, Murat, Inês, Luís S, Isenberg, David, Jacobsen, Soren, Jan Wu, Yeong-Jian, Kaneko, Yuko, Katsumata, Yasuhiro, Lau, Chak S, Legge, Alexandra C, Lerang, Karoline, Limper, Maarten, Louthrenoo, Worawit, Luo, Shue-Fen, Marinho, António, Massardo, Loreto, Mathian, Alexis, Mosca, Marta, Nikpour, Mandana, Pego-Reigosa, José M, Peschken, Christine A, Pons-Estel, Bernardo A, Pons-Estel, Guillermo J, Rahman, Anisur, Rednic, Simona, Ribi, Camillo, Ruiz-Irastorza, Guillermo, Sato, Emilia I, Saxena, Amit, Schneider, Matthias, Sebastiani, Gian Domenico, Strand, Vibeke, Svenungsson, Elisabet, Tanaka, Yoshiya, Tazi Mezalek, Zoubida, Tee, Michael L, Tincani, Angela, Touma, Zahi, Troldborg, Anne, Vasconcelos, Carlos, Vinet, Évelyne, Vital, Edward M, Voskuyl, Alexandre E, Voss, Anne, Wallace, Daniel, Ward, Michael, Zamora, Leonid D, Piga, Matteo, Chessa, Elisabetta, Morand, Eric F, Ugarte-Gil, Manuel F, Tektonidou, Maria, van Vollenhoven, Ronald, Petri, Michelle, Arnaud, Laurent ^*

Source: In The Lancet Rheumatology June 2022 4(6):e441-e449