An NK-like CAR T cell transition in CAR T cell dysfunction

Authors: Good, Charly R., Aznar, M. Angela, Kuramitsu, Shunichiro, Samareh, Parisa, Agarwal, Sangya, Donahue, Greg, Ishiyama, Kenichi, Wellhausen, Nils, Rennels, Austin K., Ma, Yujie, Tian, Lifeng, Guedan, Sonia, Alexander, Katherine A., Zhang, Zhen, Rommel, Philipp C., Singh, Nathan, Glastad, Karl M., Richardson, Max W., Watanabe, Keisuke, Tanyi, Janos L., O’Hara, Mark H., Ruella, Marco, Lacey, Simon F., Moon, Edmund K., Schuster, Stephen J., Albelda, Steven M., Lanier, Lewis L., Young, Regina M., Berger, Shelley L., June, Carl H.

Source: In Cell 9 December 2021 184(25):6081-6100

Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity

Authors: Predina, Jarrod D., Haas, Andrew R., Martinez, Marina, O’Brien, Shaun, Moon, Edmund K., Woodruff, Patrick, Stadanlick, Jason, Corbett, Christopher, Frenzel-Sulyok, Lydia, Bryski, Mitchell G., Eruslanov, Evgeniy, Deshpande, Charuhas, Langer, Corey, Aguilar, Laura K., Guzik, Brian W., Manzanera, Andrea G., Aguilar-Cordova, Estuardo, Singhal, Sunil, Albelda, Steven M.

Source: In Molecular Therapy 3 February 2021 29(2):658-670

Ligand-Induced Degradation of a CAR Permits Reversible Remote Control of CAR T Cell Activity In Vitro and In Vivo

Authors: Richman, Sarah A., Wang, Liang-Chuan, Moon, Edmund K., Khire, Uday R., Albelda, Steven M., Milone, Michael C.

Source: In Molecular Therapy 8 July 2020 28(7):1600-1613

Photodynamic Therapy and Immune Checkpoint Blockade†

Authors: Cramer, Gwendolyn M., Moon, Edmund K., Cengel, Keith A., Busch, Theresa M.

Source: Photochemistry and photobiology. 96(5):954-961

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108411823.0x000001&indx=1&recIds=ETOCvdc_100108411823.0x000001

Development of novel avenues to overcome challenges facing CAR T cells

Authors: Kim, Soyeon, Moon, Edmund K.

Source: In Translational Research September 2017 187:22-31

Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer

Authors: Singhal, Sunil, Bhojnagarwala, Pratik S., O'Brien, Shaun, Moon, Edmund K., Garfall, Alfred L., Rao, Abhishek S., Quatromoni, Jon G., Stephen, Tom Li, Litzky, Leslie, Deshpande, Charuhas, Feldman, Michael D., Hancock, Wayne W., Conejo-Garcia, Jose R., Albelda, Steven M., Eruslanov, Evgeniy B.

Source: In Cancer Cell 11 July 2016 30(1):120-135

Surgical cytoreduction restores the antitumor efficacy of a Listeria monocytogenes vaccine in malignant pleural mesothelioma

Authors: Kennedy, Gregory T., Judy, Brendan F., Bhojnagarwala, Pratik, Moon, Edmund K., Fridlender, Zvi G., Albelda, Steven M., Singhal, Sunil

Source: In Immunology Letters July 2015 166(1):28-35

Lactate Limits T Cell Proliferation via the NAD(H) Redox State

Authors: Quinn, William J., Jiao, Jing, TeSlaa, Tara, Stadanlick, Jason, Wang, Zhonglin, Wang, Liqing, Akimova, Tatiana, Angelin, Alessia, Schäfer, Patrick M., Cully, Michelle D., Perry, Caroline, Kopinski, Piotr K., Guo, Lili, Blair, Ian A., Ghanem, Louis R., Leibowitz, Michael S., Hancock, Wayne W., Moon, Edmund K., Levine, Matthew H., Eruslanov, Evgeniy B., Wallace, Douglas C., Baur, Joseph A., Beier, Ulf H.

Source: Cell reports. 33(11)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135663463.0x000001&indx=1&recIds=ETOCvdc_100135663463.0x000001

Changes in the local tumor microenvironment in recurrent cancers may explain the failure of vaccines after surgery

Authors: Predina, Jarrod, Eruslanov, Evgeniy, Judy, Brendan, Kapoor, Veena, Cheng, Guanjun, Wang, Liang-Chuan, Sun, Jing, Moon, Edmund K., Fridlender, Gregorio, Albelda, Steven, Singhal, Sunil

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Jan . 110(5), 1582-1583.

Access URL: https://www.jstor.org/stable/41992083

Treating Tumors With a Vaccinia Virus Expressing IFNβ Illustrates the Complex Relationships Between Oncolytic Ability and Immunogenicity

Authors: Wang, Liang-Chuan S, Lynn, Rachel C, Cheng, Guanjun, Alexander, Edward, Kapoor, Veena, Moon, Edmund K, Sun, Jing, Fridlender, Zvi G, Isaacs, Stuart N, Thorne, Stephen H, Albelda, Steven M

Source: In Molecular Therapy April 2012 20(4):736-748

Phenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes

Authors: Klampatsa, Astero, O'Brien, Shaun M., Thompson, Jeffrey C., Rao, Abhishek S., Stadanlick, Jason E., Martinez, Marina C., Liousia, Maria, Cantu, Edward, Cengel, Keith, Moon, Edmund K., Singhal, Sunil, Eruslanov, Evgeniy B., Albelda, Steven M.

Source: Oncoimmunology. 8(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100086051643.0x000001&indx=1&recIds=ETOCvdc_100086051643.0x000001

Intra-tumoral delivery of CXCL11 via a vaccinia virus, but not by modified T cells, enhances the efficacy of adoptive T cell therapy and vaccines

Authors: Moon, Edmund K., Wang, Liang-Chuan S., Bekdache, Kheng, Lynn, Rachel C., Lo, Albert, Thorne, Stephen H., Albelda, Steven M.

Source: Oncoimmunology. 7(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100063194108.0x000001&indx=1&recIds=ETOCvdc_100063194108.0x000001

Chimeric antigen receptor T cells are vulnerable to immunosuppressive mechanisms present within the tumor microenvironment

Authors: Beatty, Gregory L, Moon, Edmund K

Source: Oncoimmunology. 3(11)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050630550.0x000001&indx=1&recIds=ETOCvdc_100050630550.0x000001

Photodynamic Therapy and Immune Checkpoint Blockade^†.

Authors: Cramer, Gwendolyn M.¹ (AUTHOR), Moon, Edmund K.² (AUTHOR), Cengel, Keith A.¹ (AUTHOR), Busch, Theresa M.¹ (AUTHOR) Theresa.Busch@pennmedicine.upenn.edu

Source: Photochemistry & Photobiology. Sep/Oct2020, Vol. 96 Issue 5, p954-961. 8p.

Subject Terms: *PHOTODYNAMIC therapy, *IMMUNE checkpoint inhibitors, *TREATMENT effectiveness, *PROGRAMMED cell death 1 receptors, *COMBINED modality therapy, *MONOCLONAL antibodies

Photodynamic Therapy and Immune Checkpoint Blockade^†.

Authors: Cramer, Gwendolyn M., Moon, Edmund K., Cengel, Keith A., Busch, Theresa M.

Source: Photochemistry & Photobiology; Sep/Oct2020, Vol. 96 Issue 5, p954-961, 8p

Subject Terms: PHOTODYNAMIC therapy, IMMUNE checkpoint inhibitors, TREATMENT effectiveness, PROGRAMMED cell death 1 receptors, COMBINED modality therapy, MONOCLONAL antibodies

Ligand-Induced Degradation of a CAR Permits Reversible Remote Control of CAR T Cell Activity In Vitroand In Vivo

Authors: Richman, Sarah A., Wang, Liang-Chuan, Moon, Edmund K., Khire, Uday R., Albelda, Steven M., Milone, Michael C.

Source: Molecular Therapy; July 2020, Vol. 28 Issue: 7 p1600-1613, 14p

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Chapter 79 - Massive Hemoptysis

Authors: Moon, Edmund K., Haas, Andrew R.

Source: In The Intensive Care Unit Manual Edition: Second Edition. 2014:741-746

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