A structural perspective of how T cell receptors recognize the CD1 family of lipid antigen–presenting molecules

Authors: Cao, Thinh-Phat, Shahine, Adam, Cox, Liam R., Besra, Gurdyal S., Moody, D. Branch, Rossjohn, Jamie

Source: In Journal of Biological Chemistry August 2024 300(8)

Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis

Authors: Kitzmiller, Claire E., Cheng, Tan-Yun, Prandi, Jacques, Sparks, Ian L., Moody, D. Branch, Morita, Yasu S.

Source: In Journal of Lipid Research July 2024 65(7)

Human Skin T Cells Express Conserved T-Cell Receptors that Cross-React with Staphylococcal Superantigens and CD1a

Authors: Bryan, Elizabeth, Teague, Jessica E., Eligul, Sezin, Arkins, Wellington C., Moody, D. Branch, Clark, Rachael A., Van Rhijn, Ildiko

Source: In Journal of Investigative Dermatology April 2024 144(4):833-843

CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms

Authors: Huang, Shouxiong, Shahine, Adam, Cheng, Tan-Yun, Chen, Yi-Ling, Ng, Soo Weei, Balaji, Gautham R., Farquhar, Rachel, Gras, Stephanie, Hardman, Clare S., Altman, John D., Tahiri, Nabil, Minnaard, Adriaan J., Ogg, Graham S., Mayfield, Jacob A., Rossjohn, Jamie, Moody, D. Branch

Source: In Cell 12 October 2023 186(21):4583-4596

CD1 displays its own negative regulators

Authors: Shahine, Adam, Van Rhijn, Ildiko, Rossjohn, Jamie, Moody, D. Branch

Source: In Current Opinion in Immunology August 2023 83

αβ T-cell receptor recognition of self-phosphatidylinositol presented by CD1b

Authors: Farquhar, Rachel, Van Rhijn, Ildiko, Moody, D. Branch, Rossjohn, Jamie, Shahine, Adam

Source: In Journal of Biological Chemistry February 2023 299(2)

Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d

Authors: Almeida, Catarina F., Smith, Dylan G. M., Cheng, Tan-Yun, Harpur, Chris M., Batleska, Elena, Nguyen-Robertson, Catriona V., Nguyen, Tram, Thelemann, Tamara, Reddiex, Scott J. J., Li, Shihan, Eckle, Sidonia B. G., Van Rhijn, Ildiko, Rossjohn, Jamie, Uldrich, Adam P., Moody, D. Branch, Williams, Spencer J., Pellicci, Daniel G., Godfrey, Dale I.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Aug . 118(34), 1-12.

Access URL: https://www.jstor.org/stable/27075536

Higher native Peruvian genetic ancestry proportion is associated with tuberculosis progression risk

Authors: Asgari, Samira, Luo, Yang, Huang, Chuan-Chin, Zhang, Zibiao, Calderon, Roger, Jimenez, Judith, Yataco, Rosa, Contreras, Carmen, Galea, Jerome T., Lecca, Leonid, Jones, David, Moody, D. Branch, Murray, Megan B., Raychaudhuri, Soumya

Source: In Cell Genomics 13 July 2022 2(7)

Human γδ T cells recognize CD1b by two distinct mechanisms

Authors: Reijneveld, Josephine F., Ocampo, Tonatiuh A., Shahine, Adam, Gully, Benjamin S., Vantourout, Pierre, Hayday, Adrian C., Rossjohn, Jamie, Moody, D. Branch, Van Rhijn, Ildiko

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Sep . 117(37), 22944-22952.

Access URL: https://www.jstor.org/stable/26969224

Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells

Authors: Reijneveld, Josephine F., Marino, Laura, Cao, Thinh-Phat, Cheng, Tan-Yun, Dam, Dennis, Shahine, Adam, Witte, Martin D., Filippov, Dmitri V., Suliman, Sara, van der Marel, Gijsbert A., Moody, D. Branch, Minnaard, Adriaan J., Rossjohn, Jamie, Codée, Jeroen D.C., Van Rhijn, Ildiko

Source: In Journal of Biological Chemistry October 2021 297(4)

Remembering Enzo Cerundolo

Authors: Moody, D. Branch

Source: In Molecular Immunology January 2021 129:53-55

Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis.

Authors: Luo, Yang, Huang, Chuan-Chin, Howard, Nicole C., Wang, Xin, Liu, Qingyun, Li, Xinyi, Zhu, Junhao, Amariuta, Tiffany, Asgari, Samira, Ishigaki, Kazuyoshi, Calderon, Roger, Raman, Sahadevan, Ramnarine, Alexandrea K., Mayfield, Jacob A., Moody, D. Branch, Lecca, Leonid, Fortune, Sarah M., Murray, Megan B., Raychaudhuri, Soumya

Source: Nature Communications; 11/29/2024, Vol. 15 Issue 1, p1-14, 14p

Subject Terms: COVID-19 pandemic, MYCOBACTERIUM tuberculosis, GENETIC variation, COMMUNICABLE diseases, TUBERCULOSIS patients, TUBERCULOSIS

Direct recognition of an intact foreign protein by an αβ T cell receptor.

Authors: Almeida, Catarina F., Gully, Benjamin S., Jones, Claerwen M., Kedzierski, Lukasz, Gunasinghe, Sachith D., Rice, Michael T., Berry, Richard, Gherardin, Nicholas A., Nguyen, Trang T., Mok, Yee-Foong, Reijneveld, Josephine F., Moody, D. Branch, Van Rhijn, Ildiko, La Gruta, Nicole L., Uldrich, Adam P., Rossjohn, Jamie, Godfrey, Dale I.

Source: Nature Communications; 10/11/2024, Vol. 15 Issue 1, p1-18, 18p

Subject Terms: MAJOR histocompatibility complex, T cells, MOLECULAR interactions, CRYSTAL structure, T cell receptors, GLOBIN, THYMUS

Membrane Lipid Requirements of the Lysine Transporter Lyp1 from Saccharomyces cerevisiae

Authors: van 't Klooster, Joury S., Cheng, Tan-Yun, Sikkema, Hendrik R., Jeucken, Aike, Moody, D. Branch, Poolman, Bert

Source: In Journal of Molecular Biology 26 June 2020 432(14):4023-4031

CD1a and bound lipids drive T‐cell responses in human skin disease

Authors: Ogg, Graham S., Rossjohn, Jamie, Clark, Rachael A., Moody, D. Branch

Source: European journal of immunology. 53(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196452711.0x000001&indx=1&recIds=ETOCvdc_100196452711.0x000001

Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis

Authors: Tahiri, Nabil, Fodran, Peter, Jayaraman, Dhineshkumar, Buter, Jeffrey, Witte, Martin D., Ocampo, Tonatiuh A., Moody, D. Branch, Van Rhijn, Ildiko, Minnaard, Adriaan J.

Source: Angewandte Chemie international edition. 59(19):7555-7560

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106641831.0x000001&indx=1&recIds=ETOCvdc_100106641831.0x000001

Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity

Authors: Holzheimer, Mira, Reijneveld, Josephine F., Ramnarine, Alexandrea K., Misiakos, Georgios, Young, David C., Ishikawa, Eri, Cheng, Tan-Yun, Yamasaki, Sho, Moody, D. Branch, Van Rhijn, Ildiko

Source: ACS chemical biology. 15(7):1835-1841

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624357917&indx=1&recIds=ETOCRN624357917

Lipidomic scanning of self-lipids identifies headless antigens for natural killer T cells.

Authors: Tan-Yun Cheng, Praveena, T., Govindarajan, Srinath, Almeida, Catarina F., Pellicci, Daniel G., Arkins, Wellington C., Van Rhijn, Ildiko, Venken, Koen, Elewaut, Dirk, Godfrey, Dale I., Rossjohn, Jamie, Moody, D. Branch

Source: Proceedings of the National Academy of Sciences of the United States of America; 8/20/2024, Vol. 121 Issue 34, p1-10, 26p

Subject Terms: CYTOTOXIC T cells, KILLER cells, T cell receptors, CERAMIDES, AUTOANTIGENS

Lipids hide or step aside for CD1-autoreactive T cell receptors

Authors: Cotton, Rachel N, Shahine, Adam, Rossjohn, Jamie, Moody, D Branch

Source: In Current Opinion in Immunology June 2018 52:93-99

CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells

Authors: Reinink, Peter, Souter, Michael N. T., Cheng, Tan‐Yun, Gorkom, Tamara, Lenz, Stefanie, Kubler‐Kielb, Joanna, Strle, Klemen, Kremer, Kristin, Thijsen, Steven F.T., Steere, Allen C., Godfrey, Dale I., Pellicci, Daniel G., Moody, D. Branch, Rhijn, Ildiko

Source: European journal of immunology. 49(5):737-746

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093613354.0x000001&indx=1&recIds=ETOCvdc_100093613354.0x000001