Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

Authors: Ielizaveta Gorodetska, Vasyl Lukiyanchuk, Marta Gawin, Myroslava Sliusar, Annett Linge, Fabian Lohaus, Tobias Hölscher, Kati Erdmann, Susanne Fuessel, Angelika Borkowetz, Anna Wojakowska, Daniel Fochtman, Mark Reardon, Ananya Choudhury, Yasmin Antonelli, Aldo Leal-Egaña, Ayse Sedef Köseer, Uğur Kahya, Jakob Püschel, Andrea Petzold, Daria Klusa, Claudia Peitzsch, Romy Kronstein-Wiedemann, Torsten Tonn, Lukasz Marczak, Christian Thomas, Piotr Widłak, Monika Pietrowska, Mechthild Krause, Anna Dubrovska

Source: Journal of Experimental & Clinical Cancer Research, Vol 44, Iss 1, Pp 1-25 (2025)

Subject Terms: Prostate cancer, Metastasis, Liquid biopsy, MMP11, ALDH1A1, TGF-β1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/39ad058654cc4db59d1c3aa2bbba94b4

Challenges of MS‐based small extracellular vesicles proteomics

Authors: Daniel Fochtman, Lukasz Marczak, Monika Pietrowska, Anna Wojakowska

Source: Journal of Extracellular Vesicles, Vol 13, Iss 12, Pp n/a-n/a (2024)

Subject Terms: extracellular vesicles, mass spectrometry, proteomics, reliability, sEV isolation, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2001-3078

Access URL: https://doaj.org/article/33dac464fce140b99d673a824337b192

Oncoviral Infections and Small Extracellular Vesicles

Authors: Łukasz Ważny, Theresa L. Whiteside, Monika Pietrowska

Source: Viruses, Vol 16, Iss 8, p 1291 (2024)

Subject Terms: oncoviruses, small extracellular vesicles (sEV), exosomes, viral infections, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/8/1291; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/fcc58c3266304df4a5bebaa9fbfab087

Venom diversity in Naja mossambica: Insights from proteomic and immunochemical analyses reveal intraspecific differences.

Authors: Konrad K Hus, Justyna Buczkowicz, Monika Pietrowska, Vladimír Petrilla, Monika Petrillová, Jaroslav Legáth, Thea Litschka-Koen, Aleksandra Bocian

Source: PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0012057 (2024)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0012057&type=printable; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/f7d8cf634dd24da1b07b8bc822ea5446

Proteomic and metabolomic signatures of rectal tumor discriminate patients with different responses to preoperative radiotherapy

Authors: Anna Wojakowska, Lukasz Marczak, Marcin Zeman, Mykola Chekan, Ewa Zembala-Nożyńska, Krzysztof Polanski, Aleksander Strugała, Piotr Widlak, Monika Pietrowska

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: rectal cancer, radiotherapy, tissue, metabolomics, proteomics, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1323961/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/3f43c2ebf3f94730a7c3c985ab1dcc45

Late Effects of Ionizing Radiation on the Ultrastructure of Hepatocytes and Activity of Lysosomal Enzymes in Mouse Liver Irradiated In Vivo

Authors: Małgorzata Łysek-Gładysińska, Anna Wieczorek, Anna Walaszczyk, Karol Jelonek, Monika Pietrowska, Piotr Widłak, Roland Kulik, Dorota Gabryś

Source: Metabolites, Vol 14, Iss 4, p 212 (2024)

Subject Terms: ionizing radiation, liver, hepatocytes, lysosomes, autophagic vacuoles, lysosomal hydrolases, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/14/4/212; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/8baf73fc98d94bda986271b809218e4c

TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro‐angiogenic phenotype

Authors: Nils Ludwig, Saigopalakrishna S. Yerneni, Juliana H. Azambuja, Monika Pietrowska, Piotr Widłak, Cynthia S. Hinck, Alicja Głuszko, Mirosław J. Szczepański, Teresa Kärmer, Isabella Kallinger, Daniela Schulz, Richard J. Bauer, Gerrit Spanier, Steffen Spoerl, Johannes K. Meier, Tobias Ettl, Beatrice M. Razzo, Torsten E. Reichert, Andrew P. Hinck, Theresa L. Whiteside

Source: Journal of Extracellular Vesicles, Vol 11, Iss 12, Pp n/a-n/a (2022)

Subject Terms: angiogenesis, exosomes, head and neck squamous cell carcinoma, macrophages, small extracellular vesicles, TGFβ, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2001-3078

Access URL: https://doaj.org/article/f088f547bd094054be588feb402afff5

Prognostic Value of Molecular Intratumor Heterogeneity in Primary Oral Cancer and Its Lymph Node Metastases Assessed by Mass Spectrometry Imaging

Authors: Agata Kurczyk, Marta Gawin, Piotr Paul, Ewa Chmielik, Tomasz Rutkowski, Monika Pietrowska, Piotr Widłak

Source: Molecules, Vol 27, Iss 17, p 5458 (2022)

Subject Terms: cancer prognosis, head and neck squamous cell carcinoma, intratumor heterogeneity, long-term outcome, mass spectrometry imaging, tumor microenvironment, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/17/5458; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/ab9f0c9b1f02463988d26a73e6533b55

Proteomic profile of melanoma cell‐derived small extracellular vesicles in patients’ plasma: a potential correlate of melanoma progression

Authors: Monika Pietrowska, Aneta Zebrowska, Marta Gawin, Lukasz Marczak, Priyanka Sharma, Sujan Mondal, Justyna Mika, Joanna Polańska, Soldano Ferrone, John M. Kirkwood, Piotr Widlak, Theresa L. Whiteside

Source: Journal of Extracellular Vesicles, Vol 10, Iss 4, Pp n/a-n/a (2021)

Subject Terms: high‐resolution mass spectrometry (HRMS), melanoma cell‐derived exosomes (MTEX), proteomics, small extracellular vesicles (sEV), tumour‐derived exosomes (TEX), Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2001-3078

Access URL: https://doaj.org/article/85e7fb7698f447119cbb8d127eebe1e9

Proteomic and Metabolomic Profiles of T Cell-Derived Exosomes Isolated from Human Plasma

Authors: Aneta Zebrowska, Karol Jelonek, Sujan Mondal, Marta Gawin, Katarzyna Mrowiec, Piotr Widłak, Theresa Whiteside, Monika Pietrowska

Source: Cells, Vol 11, Iss 12, p 1965 (2022)

Subject Terms: CD3 antigen, exosomes, immune capture, T lymphocytes, metabolomics, proteomics, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/12/1965; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/84c7654006ca433d810b62e977494c96

Small Extracellular Vesicles in Transplant Rejection

Authors: Justyna E. Gołębiewska, Anna Wardowska, Monika Pietrowska, Anna Wojakowska, Alicja Dębska-Ślizień

Source: Cells, Vol 10, Iss 11, p 2989 (2021)

Subject Terms: small extracellular vesicles, transplantation, biomarker, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/11/2989; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/70f52faaf0204128a17ea607455fce06

Proteomes of exosomes from HPV(+) or HPV(-) head and neck cancer cells: differential enrichment in immunoregulatory proteins

Authors: Sonja Ludwig, Lukasz Marczak, Priyanka Sharma, Agata Abramowicz, Marta Gawin, Piotr Widlak, Theresa L. Whiteside, Monika Pietrowska

Source: OncoImmunology, Vol 8, Iss 7 (2019)

Subject Terms: exosomes, head and neck cancer, human papillomavirus, proteomics, immune functions, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/e0a2c5c3f90e41438848888ffc445780

Aging-Related Changes in the Ultrastructure of Hepatocytes and Cardiomyocytes of Elderly Mice Are Enhanced in ApoE-Deficient Animals

Authors: Małgorzata Łysek-Gładysińska, Anna Wieczorek, Artur Jóźwik, Anna Walaszczyk, Karol Jelonek, Grażyna Szczukiewicz-Markowska, Olaf K. Horbańczuk, Monika Pietrowska, Piotr Widłak, Dorota Gabryś

Source: Cells, Vol 10, Iss 3, p 502 (2021)

Subject Terms: aging, hepatocytes, cardiomyocytes, lysosomes, mitochondrion, lipids, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/3/502; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/c978044fec8f45e999938e1609a45156

Metabolomic Signature Discriminates Normal Human Cornea from Keratoconus—A Pilot GC/MS Study

Authors: Anna Wojakowska, Monika Pietrowska, Piotr Widlak, Dariusz Dobrowolski, Edward Wylęgała, Dorota Tarnawska

Source: Molecules, Vol 25, Iss 12, p 2933 (2020)

Subject Terms: keratoconus, cornea, ocular metabolomics, GC/MS profiling, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/12/2933; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/6af98b027b3841a4b05382a2164a2c96

Molecular and Functional Profiles of Exosomes From HPV(+) and HPV(−) Head and Neck Cancer Cell Lines

Authors: Sonja Ludwig, Priyanka Sharma, Marie-Nicole Theodoraki, Monika Pietrowska, Saigopalakrishna S. Yerneni, Stephan Lang, Soldano Ferrone, Theresa L. Whiteside

Source: Frontiers in Oncology, Vol 8 (2018)

Subject Terms: exosomes, head and neck cancer, HPV(+) and HPV(−) tumor cells, protein profiling, immune functions, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2018.00445/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/a712b1f83d274ea1bbeff5d4ccc99e85

Partial-Body Irradiation in Patients with Prostate Cancer Treated with IMRT Has Little Effect on the Composition of Serum Proteome

Authors: Monika Pietrowska, Karol Jelonek, Joanna Polanska, Anna Wojakowska, Lukasz Marczak, Ewa Chawinska, Aleksanda Chmura, Wojciech Majewski, Leszek Miszczyk, Piotr Widlak

Source: Proteomes, Vol 3, Iss 3, Pp 117-131 (2015)

Subject Terms: IMRT, mass spectrometry, prostate cancer, radiation response, serum proteomics, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.mdpi.com/2227-7382/3/3/117; https://doaj.org/toc/2227-7382

Access URL: https://doaj.org/article/3fe8ee1ad0544a83808326fed678888c

Harmonization of exosome isolation from culture supernatants for optimized proteomics analysis.

Authors: Agata Abramowicz, Lukasz Marczak, Anna Wojakowska, Szczepan Zapotoczny, Theresa L Whiteside, Piotr Widlak, Monika Pietrowska

Source: PLoS ONE, Vol 13, Iss 10, p e0205496 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC6209201?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8a5e33bd311744ce8fd0ca96570fc8d4

Antimicrobial Activity of Protein Fraction from Naja ashei Venom against Staphylococcus epidermidis

Authors: Aleksandra Bocian, Ewa Ciszkowicz, Konrad K. Hus, Justyna Buczkowicz, Katarzyna Lecka-Szlachta, Monika Pietrowska, Vladimír Petrilla, Monika Petrillova, Ľubomír Legáth, Jaroslav Legáth

Source: Molecules, Vol 25, Iss 2, p 293 (2020)

Subject Terms: naja ashei, venom proteins, antimicrobial properties, mic, biofilm, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/2/293; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/52a21bc314004f73b9a2cf7d362ef1fc

Different Types of Cellular Stress Affect the Proteome Composition of Small Extracellular Vesicles: A Mini Review

Authors: Agata Abramowicz, Piotr Widłak, Monika Pietrowska

Source: Proteomes, Vol 7, Iss 2, p 23 (2019)

Subject Terms: exosome, extracellular vesicles, genotoxic stress, heat shock, hypoxia, mass spectrometry, oxidative stress, proteome, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2227-7382/7/2/23; https://doaj.org/toc/2227-7382

Access URL: https://doaj.org/article/dc3faea2fd8e443095fa890c85105387

Challenges in the Isolation and Proteomic Analysis of Cancer Exosomes—Implications for Translational Research

Authors: Jadwiga Jablonska, Monika Pietrowska, Sonja Ludwig, Stephan Lang, Basant Kumar Thakur

Source: Proteomes, Vol 7, Iss 2, p 22 (2019)

Subject Terms: proteomics of exosomes, heterogeneity of exosomes, extracellular vesicles, cancer, tumor progression, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2227-7382/7/2/22; https://doaj.org/toc/2227-7382

Access URL: https://doaj.org/article/f4d500acf664452c8f83b541cb572ba4