Long-lasting antibody B-cell responses to SARS-CoV-2 three years after the onset of the pandemic

Authors: Molinos-Albert, Luis M. ^{1, 2, 14, ∗}, Rubio, Rocío ^{1, 2, 13}, Martín-Pérez, Carla ^{1, 2, 13}, Pradenas, Edwards ^{3, 13}, Torres, Cèlia ^{1, 2, 13}, Jiménez, Alfons ^{1, 4}, Canyelles, Mar ^{1, 2}, Vidal, Marta ^{1, 2}, Barrios, Diana ¹, Marfil, Silvia ³, Aparicio, Ester ³, Ramírez-Morros, Anna ⁵, Trinité, Benjamin ³, Vidal-Alaball, Josep ^{5, 6, 11}, Santamaria, Pere ^{7, 8}, Serra, Pau ⁷, Izquierdo, Luis ^{1, 9}, Aguilar, Ruth ^{1, 2}, Ruiz-Comellas, Anna ^{5, 6, 10, 11}, Blanco, Julià ^{3, 9, 11, 12}, Dobaño, Carlota ^{1, 2, 9, ∗∗}, Moncunill, Gemma ^{1, 2, 9, ∗∗∗}

Source: In Cell Reports 22 April 2025 44(4)

Post-vaccination IgG4 and IgG2 class switch associates with increased risk of SARS-CoV-2 infections

Authors: Martín Pérez, Carla ^{a, b, 1}, Ruiz-Rius, Sílvia ^{a, b, 1}, Ramírez-Morros, Anna ^c, Vidal, Marta ^{a, b}, Opi, D. Herbert ^{d, e, f}, Santamaria, Pere ^{g, h}, Blanco, Julià ^{i, j, k, l}, Vidal-Alaball, Josep ^{c, k, m}, Beeson, James G. ^{d, e, f}, Molinos-Albert, Luis M. ^{a, b}, Aguilar, Ruth ^{a, b}, Ruiz-Comellas, Anna ^{c, k, m, n, 1}, Moncunill, Gemma ^{a, b, j, ⁎, 1}, Dobaño, Carlota ^{a, b, j, ⁎, 1}

Source: In Journal of Infection April 2025 90(4)

The effect of Plasmodium falciparum exposure and maternal anti-circumsporozoite protein antibodies on responses to RTS,S/AS01E vaccination in infants and children: an ancillary observational immunological study to a phase 3, randomised clinical trial

Authors: Macià, Dídac ^{a, b, c}, Campo, Joseph J ^d, Jairoce, Chenjerai ^{b, e}, Mpina, Maximilian ^f, Sorgho, Hermann ^g, Dosoo, David ^h, Agnandji, Selidji Todagbe ^{i, j}, Kusi, Kwadwo Asamoah ^k, Molinos-Albert, Luis M ^{a, b}, Kariuki, Simon ^l, Daubenberger, Claudia ^{m, n}, Mordmüller, Benjamin ^{c, j, o}, Moncunill, Gemma ^{a, b, c, †}, Dobaño, Carlota ^{a, b, c, †, *}

Source: In The Lancet Infectious Diseases March 2025 25(3):335-345

Initial antigen encounter determines robust T-cell immunity against SARS-CoV-2 BA.2.86 variant three years later

Authors: Rubio, Rocío ^{a, b}, Yavlinsky, Alexei ^c, Escalera Zamudio, Marina ^d, Molinos-Albert, Luis M. ^{a, b}, Martín Pérez, Carla ^{a, b}, Pradenas, Edwards ^e, Canyelles, Mar ^{a, b}, Torres, Cèlia ^{a, b}, Tan, Cedric ^d, Swadling, Leo ^f, Ramírez-Morros, Anna ^g, Trinité, Benjamin ^e, Vidal-Alaball, Josep ^{h, i}, Aguilar, Ruth ^{a, b}, Ruiz-Comellas, Anna ^{g, h, i}, Blanco, Julià ^{e, j, k, l}, van Dorp, Lucy ^d, Balloux, François ^d, Dobaño, Carlota ^{a, b, l, ⁎}, Moncunill, Gemma ^{a, b, l, ⁎}

Source: In Journal of Infection February 2025 90(2)

High-resolution kinetics and cellular determinants of SARS-CoV-2 antibody response over two years after COVID-19 vaccination

Authors: Rubio, Rocío ^{a, b, 1}, Macià, Dídac ^{a, b, c, 1}, Barrios, Diana ^{a, b}, Vidal, Marta ^{a, b}, Jiménez, Alfons ^{a, b, d}, Molinos-Albert, Luis M. ^{a, b}, Díaz, Natalia ^{a, b}, Canyelles, Mar ^{a, b}, Lara-Escandell, Maria ^{a, b}, Planchais, Cyril ^e, Santamaria, Pere ^{f, g}, Carolis, Carlo ^h, Izquierdo, Luis ^{a, b, c}, Aguilar, Ruth ^{a, b}, Moncunill, Gemma ^{a, b, c, ⁎, 2}, Dobaño, Carlota ^{a, b, c, ⁎, 2}

Source: In Microbes and Infection February 2025 27(2)

Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller

Authors: Molinos-Albert, Luis M., Baquero, Eduard, Bouvin-Pley, Mélanie, Lorin, Valérie, Charre, Caroline, Planchais, Cyril, Dimitrov, Jordan D., Monceaux, Valérie, Vos, Matthijn, Hocqueloux, Laurent, Berger, Jean-Luc, Seaman, Michael S., Braibant, Martine, Avettand-Fenoël, Véronique, Sáez-Cirión, Asier, Mouquet, Hugo

Source: In Cell Host & Microbe 9 August 2023 31(8):1275-1287

Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm

Authors: Vamvaka, Evangelia, Farré, Gemma, Molinos-Albert, Luis M., Evans, Abbey, Canela-Xandri, Anna, Twyman, Richard M., Carrillo, Jorge, Ordóñez, Raziel A., Shattock, Robin J., O’Keefe, Barry R., Clotet, Bonaventura, Blanco, Julian, Khush, Gurdev S., Christou, Paul, Capell, Teresa

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Aug . 115(33), E7854-E7862.

Access URL: https://www.jstor.org/stable/26530284

HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria.

Authors: Planchais, Cyril, Molinos-Albert, Luis M., Rosenbaum, Pierre, Hieu, Thierry, Kanyavuz, Alexia, Clermont, Dominique, Prazuck, Thierry, Lefrou, Laurent, Dimitrov, Jordan D., Hüe, Sophie, Hocqueloux, Laurent, Mouquet, Hugo

Source: Nature Communications; 10/10/2023, Vol. 14 Issue 1, p1-17, 17p

Subject Terms: B cells, IMMUNOLOGIC memory, HIV, MEMORY, INTESTINAL abnormalities, B cell receptors, HUMORAL immunity

Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers.

Authors: Molinos-Albert, Luis M., Lorin, Valérie, Monceaux, Valérie, Orr, Sylvie, Essat, Asma, Dufloo, Jérémy, Schwartz, Olivier, Rouzioux, Christine, Meyer, Laurence, Hocqueloux, Laurent, Sáez-Cirión, Asier, Mouquet, Hugo, ANRS VISCONTI Study Group, Prazuck, Thierry, Dieuleveult, Barbara De, Bani-Sadr, Firouzé, Hentzien, Maxime, Berger, Jean-Luc, Kmiec, Isabelle, Pichancourt, Gilles

Source: Nature Communications; 4/11/2022, Vol. 13 Issue 1, p1-17, 17p

Subject Terms: HUMORAL immunity, HIV, IMMUNOLOGIC memory, T helper cells, ANTIRETROVIRAL agents, ANTIBODY formation

Anti-MPER antibodies with heterogeneous neutralization capacity are detectable in most untreated HIV-1 infected individuals.

Authors: Molinos-Albert, Luis M.¹ lmmolinos@irsicaixa.es, Carrillo, Jorge¹ jcarrillo@irsicaixa.es, Curriu, Marta¹ marta.curriu@gmail.com, Rodriguez de la Concepción, Maria L.¹ mlrodriguez@irsicaixa.es, Marfil, Silvia¹ smarfil@irsicaixa.es, García, Elisabet¹ egarcia@irsicaixa.es, Clotet, Bonaventura^1,2 bclotet@irsicaixa.es, Blanco, Julià^1,2 jblanco@irsicaixa.es

Source: Retrovirology. 2014, Vol. 11 Issue 1, p1-21. 21p.

Subject Terms: *GLYCOPROTEINS, *EPITOPES, *HIV-positive persons, *FLOW cytometry, *ENZYME-linked immunosorbent assay, *HIV, *MEMBRANE glycoproteins

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