Prospective trial of the Oncobox platform RNA sequencing bioinformatic analysis for personalized prescription of targeted drugs

Authors: Sorokin, Maksim ^{a, b, c, 1}, Garazha, Andrew ^{a, b}, Suntsova, Maria ^{c, 1}, Tkachev, Victor ^a, Poddubskaya, Elena ^{d, e}, Gaifullin, Nurshat ^f, Sushinskaya, Tatiana ^g, Lantsov, Dmitriy ^h, Borisov, Vasiliy ⁱ, Naskhletashvili, David ^j, Ilyin, Kirill ^k, Seryakov, Alexander ^k, Glusker, Alex ^c, Moisseev, Alexey ^c, Buzdin, Anton ^{b, e, l, m, ⁎}

Source: In Computers in Biology and Medicine March 2025 187

A New Approach of Detecting ALK Fusion Oncogenes by RNA Sequencing Exon Coverage Analysis.

Authors: Zakharova, Galina, Suntsova, Maria, Rabushko, Elizaveta, Mohammad, Tharaa, Drobyshev, Alexey, Seryakov, Alexander, Poddubskaya, Elena, Moisseev, Alexey, Smirnova, Anastasia, Sorokin, Maxim, Tkachev, Victor, Simonov, Alexander, Guguchkin, Egor, Karpulevich, Evgeny, Buzdin, Anton

Source: Cancers; Nov2024, Vol. 16 Issue 22, p3851, 21p

Subject Terms: RESEARCH funding, POLYMERASE chain reaction, TUMOR markers, COST benefit analysis, DESCRIPTIVE statistics, IMMUNOHISTOCHEMISTRY, GENES, ONCOGENES, ANAPLASTIC lymphoma kinase, PROTEIN-tyrosine kinases, FLUORESCENCE in situ hybridization, GENE expression profiling, SEQUENCE analysis, SENSITIVITY & specificity (Statistics)

Pharmacogenomic assessment of cisplatin-based chemotherapy outcomes in ovarian cancer

Authors: Khrunin, Andrey V, Khokhrin, Denis V, Moisseev, Alexey A, Gorbunova, Vera A, Limborska, Svetlana A

Source: Pharmacogenomics. 15(3):329-337

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121259696.0x000001&indx=1&recIds=ETOCvdc_100121259696.0x000001

Gene expression-based personalized prescription of targeted drugs in colorectal cancer.

Authors: Poddubskaya, Elena, Sorokin, Maxim, Zolotovskaya, Marianna, Suntsova, Maria, Garazha, Andrew, Moisseev, Alexey, Bondarenko, Alexey, Skrijalin, Vasiliy, Baranova, Madina, Sekacheva, Marina, Seryakov, Alexander, Buzdin, Anton

Source: Journal of clinical oncology. 40(4 suppl):151-151

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152956725.0x000001&indx=1&recIds=ETOCvdc_100152956725.0x000001

Pharmacogenomics of cisplatin-based chemotherapy in ovarian cancer patients of different ethnic origins

Authors: Khrunin, Andrey, Ivanova, Feodosia, Moisseev, Alexey, Khokhrin, Denis, Sleptsova, Yuliya, Gorbunova, Vera, Limborska, Svetlana

Source: Pharmacogenomics. 13(2):171-178

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121257968.0x000001&indx=1&recIds=ETOCvdc_100121257968.0x000001

Oncobox Platform of RNA Sequencing and Bioinformatic Analysis for Personalized Prescription of Targeted Drugs: Results of Prospective Clinical Trial NCT03724097.

Authors: Sorokin, Maxim, Garazha, Andrew, Suntsova, Maria, Tkachev, Victor, Poddubskaya, Elena, Gaifullin, Nurshat, Sushinskaya, Tatiana, Lantsov, Dmitriy, Borisov, Vasiliy, Naskhletashvili, David, llyin, Kirill, Seryakov, Alexander, Glusker, Alex, Moisseev, Alexey, Buzdin, Anton

Source: Journal of Immunotherapy & Precision Oncology; Aug2024, Vol. 7 Issue 3, p218-219, 2p

Subject Terms: RNA sequencing, DRUGS, DRUG therapy, GENE expression, PALLIATIVE treatment

Personalized targeted therapy prescription in colorectal cancer using algorithmic analysis of RNA sequencing data.

Authors: Sorokin, Maxim, Zolotovskaia, Marianna, Nikitin, Daniil, Suntsova, Maria, Poddubskaya, Elena, Glusker, Alexander, Garazha, Andrew, Moisseev, Alexey, Li, Xinmin, Sekacheva, Marina, Naskhletashvili, David, Seryakov, Alexander, Wang, Ye, Buzdin, Anton

Source: BMC Cancer; 10/31/2022, Vol. 22 Issue 1, p1-19, 19p

Transcriptomics-Guided Personalized Prescription of Targeted Therapeutics for Metastatic ALK-Positive Lung Cancer Case Following Recurrence on ALK Inhibitors.

Authors: Poddubskaya, Elena, Bondarenko, Alexey, Boroda, Alexander, Zotova, Evgenia, Glusker, Alex, Sletina, Svetlana, Makovskaia, Luidmila, Kopylov, Philipp, Sekacheva, Marina, Moisseev, Alexey, Baranova, Madina

Source: Frontiers in Oncology; 10/15/2019, p1-8, 8p

Subject Terms: LUNG cancer, ANAPLASTIC lymphoma kinase, THERAPEUTICS, DECISION support systems, DISEASE relapse

Algorithmically Deduced FREM2 Molecular Pathway Is a Potent Grade and Survival Biomarker of Human Gliomas.

Authors: Zolotovskaia, Marianna, Tkachev, Victor, Sorokin, Maxim, Garazha, Andrew, Kim, Ella, Kantelhardt, Sven Rainer, Bikar, Sven-Ernö, Zottel, Alja, Šamec, Neja, Kuzmin, Denis, Sprang, Bettina, Moisseev, Alexey, Giese, Alf, Efimov, Victor, Jovčevska, Ivana, Buzdin, Anton

Source: Cancers; Aug2021, Vol. 13 Issue 16, p4117, 1p

Subject Terms: SURVIVAL, BIOMARKERS, GLIOMAS, RNA, CELLULAR signal transduction, DESCRIPTIVE statistics, ALGORITHMS

Transcriptomic and Genomic Testing to Guide Individualized Treatment in Chemoresistant Gastric Cancer Case.

Authors: Moisseev, Alexey, Albert, Eugene, Lubarsky, Dan, Schroeder, David, Clark, Jeffrey

Source: Biomedicines; Mar2020, Vol. 8 Issue 3, p67, 1p

Subject Terms: STOMACH cancer, RNA sequencing, ESOPHAGEAL cancer, ESOPHAGEAL tumors, SOMATIC mutation, EOSINOPHILIC esophagitis