The development of a canine single-chain phage antibody library to isolate recombinant antibodies for use in translational cancer research

Authors: Lisowska, Małgorzata ^{1, 10, 11, 12, ∗}, Worrall, Erin G. ^{2, 11}, Zavadil-Kokas, Filip ^{3, 11}, Charlton, Keith ⁵, Murray, Euan ^{2, 4}, Mohtar, M. Aiman ^{2, 9}, Krejcir, Radovan ³, Hrabal, Vaclav ³, Brydon, Jack ², Urionabarrenetxea, Ainhoa Gonzalez ², Saliba, David G. ⁶, Grima, Mariana ⁶, Kalathiya, Umesh ¹, Muller, Petr ³, Krejci, Adam ³, Vojtesek, Borivoj ^{3, 8}, Ball, Kathryn L. ², Fahraeus, Robin ⁴, Argyle, David J. ⁷, Parys, Maciej ⁷, Hupp, Ted R. ^{1, 2}

Source: In Cell Reports Methods 24 March 2025 5(3)

Secretion of pro-oncogenic AGR2 protein in cancer

Authors: Moidu, Nurshahirah Ashikin, A Rahman, Nisa Syakila, Syafruddin, Saiful Effendi, Low, Teck Yew, Mohtar, M. Aiman

Source: In Heliyon September 2020 6(9)

The Sequence-specific Peptide-binding Activity of the Protein Sulfide Isomerase AGR2 Directs Its Stable Binding to the Oncogenic Receptor EpCAM

Authors: Mohtar, M. Aiman, Hernychova, Lenka ^¶, O'Neill, J. Robert ^‡, Lawrence, Melanie L. ^‡, Murray, Euan, Vojtesek, Borek ^¶, Hupp, Ted R. ^**

Source: In Molecular & Cellular Proteomics April 2018 17(4):737-763

Cholesterol accumulation in ccRCC: the role of ccRCC-initiating VHL-HIFα pathway

Authors: Mohtar, M. Aiman, Hasanah Mohd Yusuf, Siti Nur, Syafruddin, Saiful Effendi ^∗

Source: In eBioMedicine May 2024 103

PP051 RNA-seq analysis of CRISPR-Cas9 targeted AGR2 of breast cancer cells reveals potential modulators of its expression and secretion

Authors: Mohtar, M. Aiman, Zahari, Syazalina, Rahman, Nisa Syakila A., Effendi, Saiful, Abdullah-Zawawi, Muhammad-Redha, Low, Teck Yew, Hupp, Ted

Source: In ESMO Open December 2023 8(1) Supplement 6

Reflux of Endoplasmic Reticulum proteins to the cytosol inactivates tumor suppressors

Authors: Sicari, Daria, Centonze, Federica G, Pineau, Raphael, Le Reste, Pierre‐Jean, Negroni, Luc, Chat, Sophie, Mohtar, M Aiman, Thomas, Daniel, Gillet, Reynald, Hupp, Ted, Chevet, Eric, Igbaria, Aeid

Source: EMBO reports. 22(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138520887.0x000001&indx=1&recIds=ETOCvdc_100138520887.0x000001

Malaria in urban Kuala Lumpur, Malaysia from 2005 to 2017

Authors: Idris, Zulkarnain Md, Zainal, Fatin Nor Shakila, Ching, Lee Shu, Azmin, Amiruzair, Hamdan, Zakiah, Kamaruzaman, Ummi Athirah, Chan, Chim W., Mohtar, M. Aiman, Munajat, Mohd Bakhtiar, Muhammad Yasin, Azlin

Source: Travel medicine and infectious disease. 41

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135198533.0x000001&indx=1&recIds=ETOCvdc_100135198533.0x000001

Connecting Proteomics to Next‐Generation Sequencing: Proteogenomics and Its Current Applications in Biology

Authors: Low, Teck Yew, Mohtar, M. Aiman, Ang, Mia Yang, Jamal, Rahman

Source: Proteomics. 19(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083727250.0x000001&indx=1&recIds=ETOCvdc_100083727250.0x000001

Impact of the Cancer Cell Secretome in Driving Breast Cancer Progression.

Authors: Zahari, Syazalina, Syafruddin, Saiful Effendi, Mohtar, M. Aiman

Source: Cancers; May2023, Vol. 15 Issue 9, p2653, 17p

Subject Terms: PROTEINS, CANCER cell culture, SECRETION, METABOLOMICS, NEOPLASTIC cell transformation, METASTASIS, DRUG resistance, CHEMOEMBOLIZATION, BREAST tumors, WOMEN'S health

Cancer Cell-Derived PDGFB Stimulates mTORC1 Activation in Renal Carcinoma.

Authors: Abuhamad, Asmaa Y., Mohamad Zamberi, Nurul Nadia, Vanharanta, Sakari, Mohd Yusuf, Siti Nur Hasanah, Mohtar, M. Aiman, Syafruddin, Saiful Effendi

Source: International Journal of Molecular Sciences; Apr2023, Vol. 24 Issue 7, p6447, 14p

Subject Terms: TUMOR suppressor genes, CELLULAR signal transduction, RENAL cell carcinoma, CARCINOMA

Functions and mechanisms of protein disulfide isomerase family in cancer emergence.

Authors: Rahman, Nisa Syakila A., Zahari, Syazalina, Syafruddin, Saiful Effendi, Firdaus-Raih, Mohd, Low, Teck Yew, Mohtar, M. Aiman

Source: Cell & Bioscience; 8/14/2022, Vol. 12 Issue 1, p1-19, 19p

Subject Terms: PROTEIN disulfide isomerase, THIOREDOXIN, ENDOPLASMIC reticulum, TUMOR growth

Reverting TP53 Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations.

Authors: Abuhamad, Asmaa Y., Mohamad Zamberi, Nurul Nadia, Sheen, Ling, Naes, Safaa M., Mohd Yusuf, Siti Nur Hasanah, Ahmad Tajudin, Asilah, Mohtar, M. Aiman, Amir Hamzah, Amir Syahir, Syafruddin, Saiful Effendi

Source: Cells (2073-4409); May2022, Vol. 11 Issue 10, p1612-N.PAG, 16p

Subject Terms: GENOME editing, BREAST cancer, CANCER cells, TUMOR suppressor genes, MISSENSE mutation, BREAST, WORKFLOW

Short open reading frames (sORFs) and microproteins: an update on their identification and validation measures.

Authors: Leong, Alyssa Zi-Xin, Lee, Pey Yee, Mohtar, M. Aiman, Syafruddin, Saiful Effendi, Pung, Yuh-Fen, Low, Teck Yew

Source: Journal of Biomedical Science; 3/17/2022, Vol. 29 Issue 1, p1-15, 15p

Subject Terms: MASS spectrometry, PROTEIN-protein interactions, AMINO acids, CRISPRS

Integration of RNA-Seq and proteomics data identifies glioblastoma multiforme surfaceome signature.

Authors: Syafruddin, Saiful Effendi, Nazarie, Wan Fahmi Wan Mohamad, Moidu, Nurshahirah Ashikin, Soon, Bee Hong, Mohtar, M. Aiman

Source: BMC Cancer; 7/23/2021, Vol. 21 Issue 1, p1-13, 13p

Subject Terms: GLIOBLASTOMA multiforme, PROTEOMICS, CELL membranes, RNA sequencing, BRAIN tumors, DRUG accessibility

WIDENING THE BOTTLENECK OF PHOSPHOPROTEOMICS: EVOLVING STRATEGIES FOR PHOSPHOPEPTIDE ENRICHMENT.

Authors: Low, Teck Yew¹ (AUTHOR) lowteckyew@ppukm.ukm.edu.my, Mohtar, M. Aiman¹ (AUTHOR), Lee, Pey Yee¹ (AUTHOR), Omar, Nursyazwani¹ (AUTHOR), Zhou, Houjiang² (AUTHOR), Ye, Mingliang³ (AUTHOR)

Source: Mass Spectrometry Reviews. Jul2021, Vol. 40 Issue 4, p309-333. 25p.

Subject Terms: *ION exchange chromatography, *POST-translational modification, *PROTEIN domains, *AFFINITY chromatography, *MASS spectrometry

Company/Entity: JOHN Wiley & Sons Inc. JWA

The anterior gradient-2 interactome.

Authors: Delom, Frederic^1,2,3 delphine.fessart@inserm.fr, Mohtar, M. Aiman⁴, Hupp, Ted^5,6, Fessart, Delphine^1,2,3

Source: American Journal of Physiology: Cell Physiology. Jan2020, Vol. 318 Issue 1, pC40-C47. 8p.

Subject Terms: *PROTEIN disulfide isomerase, *ENDOPLASMIC reticulum, *ISOMERASES, *QUALITY control, *CELL proliferation, *MONOMERS

Impact of Chemotherapy on Extracellular Vesicles: Understanding the Chemo-EVs.

Authors: Ab Razak, Nur' Syahada, Ab Mutalib, Nurul Syakima, Mohtar, M. Aiman, Abu, Nadiah

Source: Frontiers in Oncology; 11/19/2019, Vol. 9, p1-7, 7p

Subject Terms: CANCER chemotherapy, TUMOR microenvironment, CANCER cells, CELL death, DRUG resistance in cancer cells

An Ultrasensitive Biosensor for Detection of Femtogram Levels of the Cancer Antigen AGR2 Using Monoclonal Antibody Modified Screen-Printed Gold Electrodes.

Authors: Białobrzeska, Wioleta¹, n.malinowska@ibmm.plw.bialobrzeska@ibmm.pl, Dziąbowska, Karolina², karolina.dziabowska@gmail.com, Lisowska, Małgorzata³, malgorzata.lisowska@ug.edu.pl, Mohtar, M. Aiman⁴, m.aimanmohtar@ppukm.ukm.edu.my, Muller, Petr⁵, pmuller@post.cz, Vojtesek, Borivoj⁵, vojtesek@mou.cz, Krejcir, Radovan⁵, radovan.krejcir@mou.cz, O'Neill, Robert⁶, robertoneill@nhs.net, Hupp, Ted R.^3,7, ted.hupp@ed.ac.uk, Malinowska, Natalia¹, e.biega@ibmm.pl, Bięga, Ewelina¹, d.bigus@ibmm.pl, Bigus, Daniel¹, z.cebula@ibmm.pl, Cebula, Zofia¹, sabina.zoledowska@etongroup.eu, Pala, Katarzyna², katarzyna.pala@etongroup.eu, Czaczyk, Elżbieta², ela@etongroup.eu, Żołędowska, Sabina¹, dawid@etongroup.eu, Nidzworski, Dawid¹

Source: Biosensors (2079-6374); Jun2021, Vol. 11 Issue 6, p184-184, 1p

Two Sides of the Same Coin: The Roles of KLF6 in Physiology and Pathophysiology.

Authors: Syafruddin, Saiful E.¹ (AUTHOR) effendisy@ppukm.ukm.edu.my, Mohtar, M. Aiman¹ (AUTHOR) lowteckyew@ppukm.ukm.edu.my, Wan Mohamad Nazarie, Wan Fahmi² (AUTHOR) wanfahmi@ums.edu.my, Low, Teck Yew¹ (AUTHOR)

Source: Biomolecules (2218-273X). Oct2020, Vol. 10 Issue 10, p1378-1378. 1p.

Subject Terms: *PATHOLOGICAL physiology, *POST-translational modification, *PHYSIOLOGY, *GENETIC regulation, *CARDIOVASCULAR diseases, *BIOLOGY

Revisiting the Roles of Pro-Metastatic EpCAM in Cancer.

Authors: Mohtar, M. Aiman¹ (AUTHOR) effendisy@ppukm.ukm.edu.my, Syafruddin, Saiful Effendi¹ (AUTHOR), Nasir, Siti Nurmi¹ (AUTHOR), Yew, Low Teck¹ (AUTHOR)

Source: Biomolecules (2218-273X). Feb2020, Vol. 10 Issue 2, p255. 1p.

Subject Terms: *CARCINOMA, *CELL adhesion molecules, *CANCER stem cells, *EPITHELIAL cells, *CELL adhesion