The cystic fibrosis gut as a potential source of multidrug resistant pathogens

Authors: Taylor, Steven L., Leong, Lex E.X., Sims, Sarah K., Keating, Rebecca L., Papanicolas, Lito E., Richard, Alyson, Mobegi, Fredrick M., Wesselingh, Steve, Burr, Lucy D., Rogers, Geraint B.

Source: In Journal of Cystic Fibrosis May 2021 20(3):413-420

The Contribution of Genetic Variation of Streptococcus pneumoniae to the Clinical Manifestation of Invasive Pneumococcal Disease

Authors: Cremers, Amelieke J. H., Mobegi, Fredrick M., van der Gaast–de Jongh, Christa, van Weert, Michelle, van Opzeeland, Fred J., Vehkala, Minna, Knol, Mirjam J., Bootsma, Hester J., Välimäki, Niko, Croucher, Nicholas J., Meis, Jacques F., Bentley, Stephen, van Hijum, Sacha A. F. T., Corander, Jukka, Zomer, Aldert L., Ferwerda, Gerben, de Jonge, Marien I.

Source: Clinical Infectious Diseases, 2019 Jan 01. 68(1), 61-69.

Access URL: https://www.jstor.org/stable/26574154

Long-Term Azithromycin Reduces Haemophilus influenzae and Increases Antibiotic Resistance in Severe Asthma

Authors: Taylor, Steven L., Leong, Lex E. X., Mobegi, Fredrick M., Choo, Jocelyn M., Wesselingh, Steve, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L.

Source: American journal of respiratory and critical care medicine. 200(3):309-317

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621029494&indx=1&recIds=ETOCRN621029494

Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut

Authors: Wang, Yanan, Leong, Lex E.X., Keating, Rebecca L., Kanno, Tokuwa, Abell, Guy C.J., Mobegi, Fredrick M., Choo, Jocelyn M., Wesselingh, Steve L., Mason, A. James, Burr, Lucy D., Rogers, Geraint B.

Source: Gut microbes. 10(3):367-381

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081956877.0x000001&indx=1&recIds=ETOCvdc_100081956877.0x000001

Genetic dissection of domestication traits in interspecific chickpea populations.

Authors: Newman, Toby E., Jacques, Silke, Grime, Christy, Mobegi, Fredrick M., Kamphuis, Fiona L., Khentry, Yuphin, Lee, Robert, Kamphuis, Lars G.

Source: Plant Genome; Mar2024, Vol. 17 Issue 1, p1-15, 15p

Advances and perspectives in computational prediction of microbial gene essentiality

Authors: Mobegi, Fredrick M., Zomer, Aldert, de Jonge, Marien I., van Hijum, Sacha A. F. T.

Source: Briefings in functional genomics. 16(2):70-79

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620630237&indx=1&recIds=ETOCRN620630237

Analysis of differentially expressed Sclerotinia sclerotiorum genes during the interaction with moderately resistant and highly susceptible chickpea lines.

Authors: Mwape, Virginia W.^1,2 (AUTHOR) virginia.wainaina@postgrad.curtin.edu.au, Mobegi, Fredrick M.¹ (AUTHOR), Regmi, Roshan^1,2 (AUTHOR), Newman, Toby E.¹ (AUTHOR), Kamphuis, Lars G.^1,2 (AUTHOR) lars.kamphuis@curtin.edu.au, Derbyshire, Mark C.¹ (AUTHOR)

Source: BMC Genomics. 5/8/2021, Vol. 22 Issue 1, p1-14. 14p.

Subject Terms: *SCLEROTINIA sclerotiorum, *CHICKPEA, *MOLECULAR biology, *GENES, *GENE expression, *RNA sequencing

Report from the extended HLA‐DPA1 ~ promoter ~ HLA‐DPB1 haplotype of the 18th international HLA and immunogenetics workshop.

Authors: Truong, Linh, Matern, Benedict M., El‐Lagta, Naser, Mobegi, Fredrick M., Askar, Medhat, Ogret, Yeliz, Oguz, Fatma S., Kwok, Janette, D'Orsogna, Lloyd, Martinez, Patricia, Petersdorf, Effie, Tilanus, Marcel G. J., De Santis, Dianne

Source: HLA: Immune Response Genetics; Dec2023, Vol. 102 Issue 6, p690-706, 17p

Subject Terms: HAPLOTYPES, HEMATOPOIETIC stem cells, ALLELES, GENETIC variation, SINGLE nucleotide polymorphisms, IMMUNOGENETICS, STEM cell transplantation

Resolving intergenotypic Striga resistance in sorghum.

Authors: Mutinda, Sylvia^1,2 (AUTHOR), Mobegi, Fredrick M³ (AUTHOR), Hale, Brett⁴ (AUTHOR), Dayou, Olivier⁵ (AUTHOR), Ateka, Elijah⁶ (AUTHOR), Wijeratne, Asela⁴ (AUTHOR), Wicke, Susann⁵ (AUTHOR), Bellis, Emily S⁷ (AUTHOR) runo.steve@ku.ac.ke, Runo, Steven^2,5 (AUTHOR) runo.steve@ku.ac.ke

Source: Journal of Experimental Botany. 9/13/2023, Vol. 74 Issue 17, p5294-5306. 13p.

Subject Terms: *WITCHWEEDS, *PURPLE witchweed, *PARASITIC plants, *GENE families, *GENE regulatory networks, *SORGHUM

Geographic Terms: SUB-Saharan Africa

From microbial gene essentiality to novel antimicrobial drug targets.

Authors: Mobegi, Fredrick M.^1,2 (AUTHOR), van Hijum, Sacha A. F. T.^2,3 (AUTHOR) Sacha.vanHijum@radboudumc.nl, Burghout, Peter¹ (AUTHOR), Bootsma, Hester J.¹ (AUTHOR), de Vries, Stefan P. W.^1,4 (AUTHOR), van der Gaast-de Jongh, Christa E.¹ (AUTHOR), Simonetti, Elles¹ (AUTHOR), Langereis, Jeroen D.¹ (AUTHOR), Hermans, Peter W. M.^1,5 (AUTHOR), de Jonge, Marien I.¹ (AUTHOR), Zomer, Aldert^1,2 (AUTHOR) Aldert.zomer@radboudumc.nl

Source: BMC Genomics. 2014, Vol. 15 Issue 1, p958-968. 11p. 1 Color Photograph, 2 Diagrams, 3 Charts.

Intestinal microbiology shapes population health impacts of diet and lifestyle risk exposures in Torres Strait Islander communities.

Authors: Mobegi, Fredrick M.^1,2, Leong, Lex E. X.¹, Thompson, Fintan^1,3, Taylor, Sean M.³, Harriss, Linton R.³, Choo, Jocelyn M.^1,2, Taylor, Steven L.^1,2, Wesselingh, Steve L.⁴, McDermott, Robyn^3,5, Ivey, Kerry L.^1,6,7 kivey@hsph.harvard.edu, Rogers, Geraint B.^1,2 Geraint.Rogers@sahmri.com

Source: eLife. 10/19/2020, p1-18. 18p.

Subject Terms: *TORRES Strait Islanders, *GUT microbiome, *RISK exposure, *SYSTOLIC blood pressure, *POPULATION health, *FECAL contamination, *COMMUNITIES, *POOR communities

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Long-Term Azithromycin Reduces and Increases Antibiotic Resistance in Severe Asthma.

Authors: Taylor, Steven L, Leong, Lex E X, Mobegi, Fredrick M, Choo, Jocelyn M, Wesselingh, Steve, Yang, Ian A, Upham, John W, Reynolds, Paul N, Hodge, Sandra, James, Alan L, Jenkins, Christine, Peters, Matthew J, Baraket, Melissa, Marks, Guy B, Gibson, Peter G, Rogers, Geraint B, Simpson, Jodie L

Source: American Journal of Respiratory & Critical Care Medicine; 3/15/2019, Vol. 199 Issue 6, pN.PAG-N.PAG, 1p

Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy.

Authors: Taylor, Steven L., Leong, Lex E. X., Mobegi, Fredrick M., Choo, Jocelyn M., Burr, Lucy D., Wesselingh, Steve, Rogers, Geraint B.

Source: Multidisciplinary Respiratory Medicine; 8/9/2018 Supplement 1, Vol. 13 Issue 1, pN.PAG-N.PAG, 1p

Subject Terms: ANTIBIOTICS, METAGENOMICS, BRONCHIECTASIS, NUCLEIC acid isolation methods, MICROBIAL sensitivity tests