Real-World Multicenter Study of PD-1 Blockade in HIV-Associated Classical Hodgkin Lymphoma Across the United States

Authors: Lurain, Kathryn, Zarif, Talal El, Ramaswami, Ramya, Nassar, Amin H., Adib, Elio, Abdel-Wahab, Noha, Chintapally, Nikita, Drolen, Claire E., Feldman, Tatyana, Haykal, Tarek, Nebhan, Caroline A., Thiruvengadam, Swetha Kambhampati, Li, Mingjia, Mittra, Arjun, Lorentsen, Michael, Kim, Chul, Drakaki, Alexandra, Morse, Michael, Johnson, Douglas B., Mangla, Ankit, Dittus, Christopher, Ravi, Praful, Baiocchi, Robert A., Chiao, Elizabeth Y., Rubinstein, Paul G., Yellapragada, Sarvari V., LaCasce, Ann S., Sonpavde, Guru P., Naqash, Abdul Rafeh, Herrera, Alex F.

Source: In Clinical Lymphoma, Myeloma and Leukemia August 2024 24(8):523-530

Safety and Activity of Immune Checkpoint Inhibitors in People Living With HIV and Cancer: A Real-World Report From the Cancer Therapy Using Checkpoint Inhibitors in People Living With HIV-International (CATCH-IT) Consortium

Authors: El Zarif, Talal, Nassar, Amin H., Adib, Elio, Fitzgerald, Bailey G., Huang, Jiaming, Mouhieddine, Tarek H., Rubinstein, Paul G., Nonato, Taylor, McKay, Rana R., Li, Mingjia, Mittra, Arjun, Owen, Dwight H., Baiocchi, Robert A., Lorentsen, Michael, Dittus, Christopher, Dizman, Nazli, Falohun, Adewunmi, Abdel-Wahab, Noha, Diab, Adi, Bankapur, Anand, Reed, Alexandra, Kim, Chul, Arora, Aakriti, Shah, Neil J., El-Am, Edward, Kozaily, Elie, Abdallah, Wassim, Al-Hader, Ahmad, Abu Ghazal, Batool, Saeed, Anwaar, Drolen, Claire, Lechner, Melissa G., Drakaki, Alexandra, Baena, Javier, Nebhan, Caroline A., Haykal, Tarek, Morse, Michael A., Cortellini, Alessio, Pinato, David J., Dalla Pria, Alessia, Hall, Evan, Bakalov, Veli, Bahary, Nathan, Rajkumar, Aarthi, Mangla, Ankit, Shah, Vishal, Singh, Parminder, Aboubakar Nana, Frank, Lopetegui-Lia, Nerea, Dima, Danai, Dobbs, Ryan W., Funchain, Pauline, Saleem, Rabia, Woodford, Rachel, Long, Georgina V., Menzies, Alexander M., Genova, Carlo, Barletta, Giulia, Puri, Sonam, Florou, Vaia, Idossa, Dame, Saponara, Maristella, Queirolo, Paola, Lamberti, Giuseppe, Addeo, Alfredo, Bersanelli, Melissa, Freeman, Dory, Xie, Wanling, Reid, Erin G., Chiao, Elizabeth Y., Sharon, Elad, Johnson, Douglas B., Ramaswami, Ramya, Bower, Mark, Emu, Brinda, Marron, Thomas U., Choueiri, Toni K., Baden, Lindsey R., Lurain, Kathryn, Sonpavde, Guru P., Naqash, Abdul Rafeh

Source: Journal of clinical oncology. 41(21):3712-3723

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193353001.0x000001&indx=1&recIds=ETOCvdc_100193353001.0x000001

BCL-xL inhibition potentiates cancer therapies by redirecting the outcome of p53 activation from senescence to apoptosis

Authors: Bharti, Vijaya, Watkins, Reese, Kumar, Amrendra, Shattuck-Brandt, Rebecca L., Mossing, Alexis, Mittra, Arjun, Shen, Chengli, Tsung, Allan, Davies, Alexander E., Hanel, Walter, Reneau, John C., Chung, Catherine, Sizemore, Gina M., Richmond, Ann, Weiss, Vivian L., Vilgelm, Anna E.

Source: In Cell Reports 20 December 2022 41(12)

A phase II study of peri-operative NovoTTF-200T(P) in combination with gemcitabine and nab-paclitaxel for resectable pancreatic adenocarcinoma: Big Ten Cancer Research Consortium (BTCRC-GI21-500).

Authors: Khorasanchi, Adam, Noonan, Anne M., Jin, Ning, Hays, John L., Roychowdhury, Sameek, Malalur, Pannaga, Rahman, Shafia, Cloyd, Jordan M., Dillhoff, Mary, Tsai, Susan, Mittra, Arjun, Manne, Ashish

Source: Journal of Clinical Oncology; 2025 Supplement 4, Vol. 43, pTPS795-TPS795, 121p

Outcomes of Pregnancy During Immunotherapy Treatment for Cancer: Analysis of Clinical Trials Sponsored by the National Cancer Institute

Authors: Mittra, Arjun, Naqash, Abdul Rafeh, Murray, James H., Finnigan, Shanda, Kwak‐Kim, Joanne, Ivy, S. Percy, Chen, Alice P., Sharon, Elad

Source: Oncologist. 26(10):e1883-e1886

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131000654.0x000001&indx=1&recIds=ETOCvdc_100131000654.0x000001

The emerging landscape of immune checkpoint inhibitor based clinical trials in adults with advanced rare tumors

Authors: Mittra, Arjun, Takebe, Naoko, Florou, Vaia, Chen, Alice P, Naqash, Abdul Rafeh

Source: Human vaccines & immunotherapeutics. 17(7):1935-1939

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127335499.0x000001&indx=1&recIds=ETOCvdc_100127335499.0x000001

Mature MUC5AC Expression in Resected Pancreatic Ductal Adenocarcinoma Predicts Treatment Response and Outcomes.

Authors: Manne, Ashish, Esnakula, Ashwini, Sheel, Ankur, Sara, Amir, Manne, Upender, Paluri, Ravi Kumar, He, Kai, Yang, Wancai, Sohal, Davendra, Kasi, Anup, Noonan, Anne M., Mittra, Arjun, Hays, John, Roychowdhury, Sameek, Malalur, Pannaga, Rahman, Shafia, Jin, Ning, Cloyd, Jordan M., Tsai, Susan, Ejaz, Aslam

Source: International Journal of Molecular Sciences; Aug2024, Vol. 25 Issue 16, p9041, 14p

Subject Terms: PANCREATIC duct, NEOADJUVANT chemotherapy, OVERALL survival, PROGRESSION-free survival, PANCREATIC cancer

Future Approaches to Precision Oncology–Based Clinical Trials

Authors: Mittra, Arjun, Moscow, Jeffrey A.

Source: Cancer journal. 25(4):300-304

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100086050343.0x000001&indx=1&recIds=ETOCvdc_100086050343.0x000001

Molecular network, pathway, and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy

Authors: Haddad, Dana, Socci, Nicholas, Chen, Chun-Hao, Chen, Nanhai G, Zhang, Qian, Carpenter, Susanne G, Mittra, Arjun, Szalay, Aladar A, Fong, Yuman

Source: In Molecular Therapy - Oncolytics 2016 3

Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors.

Authors: Mittra, Arjun^1,2 (AUTHOR), Coyne, Geraldine H. O' Sullivan¹ (AUTHOR), Zlott, Jennifer¹ (AUTHOR), Kummar, Shivaani^1,3 (AUTHOR), Meehan, Robert¹ (AUTHOR), Rubinstein, Lawrence⁴ (AUTHOR), Juwara, Lamin⁵ (AUTHOR), Wilsker, Deborah⁶ (AUTHOR), Ji, Jiuping⁶ (AUTHOR), Miller, Brandon⁶ (AUTHOR), Navas, Tony^6,7 (AUTHOR), Ferry-Galow, Katherine V.⁶ (AUTHOR), Voth, Andrea Regier⁸ (AUTHOR), Chang, Ting-Chia⁹ (AUTHOR), Jiwani, Shahanawaz⁹ (AUTHOR), Parchment, Ralph E.⁶ (AUTHOR), Doroshow, James H.^1,10 (AUTHOR), Chen, Alice P.¹ (AUTHOR) chenali@mail.nih.gov

Source: Cancer Chemotherapy & Pharmacology. Mar2024, Vol. 93 Issue 3, p177-189. 13p.

Subject Terms: *DNA repair, *POLY ADP ribose, *POLY(ADP-ribose) polymerase, *MONONUCLEAR leukocytes, *METASTATIC breast cancer, *HORMONE receptor positive breast cancer

Phase Ib adaptive study of dasatinib for the prevention of oxaliplatin-induced neuropathy in patients with gastrointestinal (GI) cancers receiving FOLFOX chemotherapy with or without bevacizumab.

Authors: Noonan, Anne M., Schnell, Patrick, Trunzo, Danielle, Thornton, Wendy, Malalur, Pannaga G., Manne, Ashish, Abushahin, Laith I., Rahman, Shafia, Jin, Ning, Hays, John L., Elkhatib, Rifat T., Mittra, Arjun, Roychowdhury, Sameek, Lustberg, Maryam B., Sparreboom, Alex, Hu, Shuiying

Source: Journal of Clinical Oncology; 2024 Supplement 3, Vol. 42, p745-745, 42p

Mucin 5 AC (MUC5AC) to predict pathologic treatment response (TR) to neoadjuvant chemotherapy (NAT) in resected-pancreatic ductal adenocarcinoma (R-PDA).

Authors: Manne, Ashish, Sheel, Ankur, Sara, Amir, Noonan, Anne M., Yu, Lianbo, Yang, Wancai, Hays, John L., Mittra, Arjun, Malalur, Pannaga G., Rahman, Shafia, Roychowdhury, Sameek, Elkatib, Rifat, Jin, Ning, Cloyd, Jordan M., Dillhoff, Mary, Ejaz, Aslam, Esnakula, Ashwini K.

Source: Journal of Clinical Oncology; 2024 Supplement 3, Vol. 42, p690-690, 117p

The impact of a pancreatic cancer multi-disciplinary clinic on patient-centric outcomes.

Authors: Hannon, Connor, Quinn, Patrick L., Iacono, Stephanie, Konik, Rachel, Sarna, Angela, Di Tosto, Gennaro, Maxey-Kohn, Krista, Cloyd, Jordan M., Pawlik, Timothy M., Manilchuck, Adrei, Noonan, Anne M., Mittra, Arjun, Rahman, Shafia, Malalur, Pannaga G., Dillhoff, Mary, Manne, Ashish, Ejaz, Aslam

Source: Journal of Clinical Oncology; 2024 Supplement 3, Vol. 42, p641-641, 117p

A phase I clinical trial of riluzole in combination with mFOLFOX6 and bevacizumab in treating patients with metastatic colorectal cancer.

Authors: Li, Chunjie, Noonan, Anne M., Hays, John L., Roychowdhury, Sameek, Malalur, Pannaga G., Elkhatib, Rifat T., Manne, Ashish, Mittra, Arjun, Rahman, Shafia, Phelps, Mitch A., Liang, Beiyuan, Storts, Hadyen, Khan, Misbah, Zhang, Evan, Zheng, Xinru, Miles, Wayne, Wang, Jing, Jin, Ning

Source: Journal of Clinical Oncology; 2024 Supplement 3, Vol. 42, p101-101, 235p

Safety and efficacy of immune checkpoint inhibitors in advanced penile cancer: report from the Global Society of Rare Genitourinary Tumors.

Authors: Zarif, Talal El, Nassar, Amin H, Pond, Gregory R, Zhuang, Tony Zibo, Master, Viraj, Nazha, Bassel, Niglio, Scot, Simon, Nicholas, Hahn, Andrew W, Pettaway, Curtis A, Tu, Shi-Ming, Abdel-Wahab, Noha, Velev, Maud, Flippot, Ronan, Buti, Sebastiano, Maruzzo, Marco, Mittra, Arjun, Gheeya, Jinesh, Yang, Yuanquan, Rodriguez, Pablo Alvarez

Source: JNCI: Journal of the National Cancer Institute; Dec2023, Vol. 115 Issue 12, p1605-1615, 11p

Subject Terms: IPILIMUMAB, IMMUNE checkpoint inhibitors, PENILE cancer, SQUAMOUS cell carcinoma, PROGRESSION-free survival, ADVERSE health care events

Irreversible electroporation facilitates gene transfer of a GM-CSF plasmid with a local and systemic response

Authors: Au, Joyce T., Mittra, Arjun, Song, Tae Jin, Cavnar, Michael, Jun, Kyonghwa, Carson, Joshua, Gholami, Sepideh, Haddad, Dana, Gaujoux, Sebastien, Monette, Sebastien, Ezell, Paula, Wolchok, Jedd, Fong, Yuman

Source: In Surgery September 2013 154(3):496-503

RT-PCR Increases Detection of Submicroscopic Peritoneal Metastases in Gastric Cancer and Has Prognostic Significance

Authors: Wong, Joyce, Kelly, Kaitlyn Jane, Mittra, Arjun, Gonen, Mithat, Allen, Peter, Fong, Yuman, Coit, Daniel

Source: In Journal of Gastrointestinal Surgery May 2012 16(5):889-896

Irreversible electroporation is a surgical ablation technique that enhances gene transfer

Authors: Au, Joyce T., Wong, Joyce, Mittra, Arjun, Carpenter, Susanne, Haddad, Dana, Carson, Joshua, Jayaraman, Shiva, Monette, Sebastien, Solomon, Stephen B., Ezell, Paula, Fong, Yuman

Source: In Surgery 2011 150(3):474-479

A Third-Generation Herpesvirus Is Effective Against Gastroesophageal Cancer

Authors: Wong, Joyce, Kelly, Kaitlyn, Mittra, Arjun, Gonzalez, Segundo Jaime, Song, Kyo Young, Simpson, Guy, Coffin, Robert, Fong, Yuman

Source: In Journal of Surgical Research 2010 163(2):214-220

Stereotactic Body Radiation Therapy (SBRT) Plus Immune Checkpoint Inhibitors (ICI) in Hepatocellular Carcinoma and Cholangiocarcinoma.

Authors: Jiang, Joanna, Diaz, Dayssy Alexandra, Nuguru, Surya Pratik, Mittra, Arjun, Manne, Ashish

Source: Cancers; Jan2023, Vol. 15 Issue 1, p50, 13p

Subject Terms: IMMUNE checkpoint inhibitors, CHOLANGIOCARCINOMA, RADIOEMBOLIZATION, STEREOTAXIC techniques, CHEMOEMBOLIZATION, PROTEIN-tyrosine kinase inhibitors, GEMCITABINE, CISPLATIN, RADIOTHERAPY, BEVACIZUMAB, HEPATOCELLULAR carcinoma, IMMUNOTHERAPY