Involvement of Parkin‐mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease‐related sarcopenia

Authors: Akihiko Ito, Mitsuo Hashimoto, Jun Tanihata, Sachi Matsubayashi, Ryoko Sasaki, Shota Fujimoto, Hironori Kawamoto, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Yu Fujita, Daisuke Takekoshi, Sabro Ito, Shunsuke Minagawa, Takanori Numata, Hiromichi Hara, Tatsuki Matsuoka, Jun Udaka, Jun Araya, Mitsuru Saito, Kazuyoshi Kuwano

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1864-1882 (2022)

Subject Terms: COPD, Parkin, Muscle atrophy, Cigarette smoke, Muscle contraction, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/ad895a5d387e4cd6855dea08a616154a

Efficacy of benralizumab for patients with severe eosinophilic asthma: a retrospective, real-life study

Authors: Takanori Numata, Hanae Miyagawa, Saiko Nishioka, Keitaro Okuda, Hirofumi Utsumi, Mitsuo Hashimoto, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Kazuyoshi Kuwano

Source: BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-10 (2020)

Subject Terms: Eosinophilic asthma, Benralizumab, Eosinophilic chronic rhinosinusitis, Global evaluation of treatment effectiveness, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12890-020-01248-x; https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/dad4c27f3770442ba57c71cc9b082581

Efficacy of mepolizumab for patients with severe asthma and eosinophilic chronic rhinosinusitis

Authors: Takanori Numata, Katsutoshi Nakayama, Hirofumi Utsumi, Kenji Kobayashi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Kazuyoshi Kuwano

Source: BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)

Subject Terms: Asthma, Mepolizumab, Eosinophilic chronic rhinosinusitis, Predictive factor, Staphylococcus enterotoxin, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12890-019-0952-1; https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/15a0fc23ace545159587a6dcd813756e

Risk factors of postoperative pulmonary complications in patients with asthma and COPD

Authors: Takanori Numata, Katsutoshi Nakayama, Satoko Fujii, Yoko Yumino, Nayuta Saito, Masahiro Yoshida, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Yumi Kaneko, Kazuyoshi Kuwano

Source: BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-8 (2018)

Subject Terms: Risk factors, Postoperative pulmonary complication, Asthma, COPD, Eosinophils, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12890-017-0570-8; https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/d3b90ddb33734d108fc053a57367d64e

Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy

Authors: Yusuke Kurita, Jun Araya, Shunsuke Minagawa, Hiromichi Hara, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Kazuya Tsubouchi, Nahoko Sato, Masahiro Yoshida, Kenji Kobayashi, Saburo Ito, Yu Fujita, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Yutaka Yoshii, Takeo Ishikawa, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama, Kazuyoshi Kuwano

Source: Respiratory Research, Vol 18, Iss 1, Pp 1-14 (2017)

Subject Terms: Autophagy, IPF, Myofibroblast, Mitophagy, Pirfenidone, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12931-017-0600-3; https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/1146926490a44a5c8c9022cb1d7ba748

Predictors of the enhanced response to mepolizumab treatment for severe eosinophilic asthma: A retrospective, long-term study

Authors: Takanori Numata, Hanae Miyagawa, Hironori Kawamoto, Masahiro Yoshida, Hirofumi Utsumi, Mitsuo Hashimoto, Shunsuke Minagawa, Hiromichi Hara, Jun Araya, Kazuyoshi Kuwano

Source: Cogent Medicine, Vol 7, Iss 1 (2020)

Subject Terms: eosinophilic asthma, mepolizumab, age, body mass index, eosinophilic chronic rhinosinusitis, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2331-205X

Access URL: https://doaj.org/article/f8e3528a885541f196ce6ed3cb3639bd

Uso da tonometria de ar em pesquisas populacionais - comparação com o tonômetro de Goldmann em indivíduos com suspeita de hipertensão ocular

Authors: Luiz Augusto Tolomei, Mitsuo Hashimoto, Caroline Ferreira da Silva Mazeto, Augusto Tomimatsu Shimauti, Maria Rosa Bet de Moraes Silva, Carlos Roberto Padovani, Silvana Artioli Schellini

Source: Revista Brasileira de Oftalmologia, Vol 75, Iss 3, Pp 209-213 (2016)

Subject Terms: Tonometria ocular/métodos, Glaucoma, Hipertensão ocular/epidemiologia, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802016000300209&lng=en&tlng=en; https://doaj.org/toc/1982-8551

Access URL: https://doaj.org/article/6a05e2d06fdb451f8f93666f712d1272

Biocompatibility of Ferrara intracorneal ring segment with and without chondroitin sulfate coating: clinical and histopathological evaluation in rabbits

Authors: Eduardo Andreghetti, Mitsuo Hashimoto, Maria Aparecida Custódio Domingues, Vitor Andrigheti Coronado Antunes, Paulo de Souza Segundo, Maria Rosa Bet de Moraes Silva

Source: Acta Cirúrgica Brasileira, Vol 28, Iss 9, Pp 632-640 (2013)

Subject Terms: Prosthesis Implantation, Corneal Neovascularization, Chondroitin Sulfates, Cornea, Rabbits, Surgery, RD1-811

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000900002&tlng=en; http://www.scielo.br/pdf/acb/v28n9/v28n9a02.pdf; https://doaj.org/toc/0102-8650

Access URL: https://doaj.org/article/d88b1a88b92b4e95a8041f55351d7a37

Diagnosis for gear tooth surface damage by empirical mode decomposition in cyclic fatigue test

Authors: Qingrong FAN, Kiyotaka IKEJO, Kazuteru NAGAMURA, Masato KAWADA, Mitsuo HASHIMOTO

Source: Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 8, Iss 3, Pp JAMDSM0039-JAMDSM0039 (2014)

Subject Terms: gear, damage diagnosis, empirical mode decompositions, support vector machines, failure feature vectors, pitting, Engineering machinery, tools, and implements, TA213-215, Mechanical engineering and machinery, TJ1-1570

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/jamdsm/8/3/8_2014jamdsm0039/_pdf/-char/en; https://doaj.org/toc/1881-3054

Access URL: https://doaj.org/article/58ad0a61c2a84e2a9eaf380f599bea39

Gear damage diagnosis and classification based on support vector machines

Authors: Qingrong FAN, Kiyotaka IKEJO, Kazuteru NAGAMURA, Masato KAWADA, Mitsuo HASHIMOTO

Source: Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 8, Iss 3, Pp JAMDSM0021-JAMDSM0021 (2014)

Subject Terms: gear, damage diagnosis, failure feature vector, statistical parameters, principal component analysis, support vector machines, Engineering machinery, tools, and implements, TA213-215, Mechanical engineering and machinery, TJ1-1570

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/jamdsm/8/3/8_2014jamdsm0021/_pdf/-char/en; https://doaj.org/toc/1881-3054

Access URL: https://doaj.org/article/1b028ddc50904f78b0226d427a696074

Application of statistical parameters and discrete wavelet transform to gear damage diagnosis

Authors: Qingrong FAN, Kiyotaka IKEJO, Kazuteru NAGAMURA, Masato KAWADA, Mitsuo HASHIMOTO

Source: Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 8, Iss 2, Pp JAMDSM0013-JAMDSM0013 (2014)

Subject Terms: gear, damage diagnosis, residual signal, discrete wavelet transform, statistical parameters, Engineering machinery, tools, and implements, TA213-215, Mechanical engineering and machinery, TJ1-1570

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/jamdsm/8/2/8_2014jamdsm0013/_pdf/-char/en; https://doaj.org/toc/1881-3054

Access URL: https://doaj.org/article/36db5d3700a242be9ab1ed4442336499

Enteric granule-containing tablets

Chaperone-Mediated Autophagy Suppresses Apoptosis via Regulation of the Unfolded Protein Response during Chronic Obstructive Pulmonary Disease Pathogenesis.

Authors: Yusuke Hosaka, Jun Araya, Yu Fujita, Tsukasa Kadota, Kazuya Tsubouchi, Masahiro Yoshida, Shunsuke Minagawa, Hiromichi Hara, Hironori Kawamoto, Naoaki Watanabe, Akihiko Ito, Akihiro Ichikawa, Nayuta Saito, Keitaro Okuda, Junko Watanabe, Daisuke Takekoshi, Hirofumi Utsumi, Mitsuo Hashimoto, Hiroshi Wakui, Saburo Ito

Source: Journal of Immunology; Sep2020, Vol. 205 Issue 5, p1256-1267, 12p

Involvement of GPx4-Regulated Lipid Peroxidation in Idiopathic Pulmonary Fibrosis Pathogenesis.

Authors: Kazuya Tsubouchi, Jun Araya, Masahiro Yoshida, Taro Sakamoto, Tomoko Koumura, Shunsuke Minagawa, Hiromichi Hara, Yusuke Hosaka, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Yu Fujita, Hirofumi Utsumi, Mitsuo Hashimoto, Hiroshi Wakui, Takanori Numata, Yumi Kaneko

Source: Journal of Immunology; 10/15/2019, Vol. 203 Issue 8, p2076-2087, 12p

Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis.

Authors: Nayuta Saito, Jun Araya, Saburo Ito, Shunsuke Minagawa, Hiromichi Hara, Akihiko Ito, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Masahiro Yoshida, Yu Fujita, Hirofumi Utsumi, Yusuke Kurita, Kenji Kobayashi, Mitsuo Hashimoto, Hiroshi Wakui, Takanori Numata, Yumi Kaneko, Katsutoshi Nakayama, Kazuyoshi Kuwano

Source: Journal of Immunology; Mar2019, Vol. 202 Issue 5, p1428-1440, 13p

Role of IL-17A in murine models of COPD airway disease.

Authors: Haruhiko Yanagisawa¹ (AUTHOR), Mitsuo Hashimoto¹ (AUTHOR), Shunsuke Minagawa¹ (AUTHOR), Naokib Takasaka¹ (AUTHOR), Ma, Royce¹ (AUTHOR), Moermans, Catherine¹ (AUTHOR), Ito, Saburo¹ (AUTHOR), Araya, Jun² (AUTHOR), Budelsky, Alison³ (AUTHOR), Goodsell, Amanda⁴ (AUTHOR), Baron, Jody L.⁴ (AUTHOR), Nishimura, Stephen L.¹ (AUTHOR) stephen.nishimura@ucsf.edu

Source: American Journal of Physiology: Lung Cellular & Molecular Physiology. Jan2017, Vol. 312 Issue 1, pL122-L130. 9p. 5 Graphs.

Metformin attenuates lung fibrosis development via NOX4 suppression.

Authors: Nahoko Sato, Naoki Takasaka, Masahiro Yoshida, Kazuya Tsubouchi, Shunsuke Minagawa, Jun Araya, Nayuta Saito, Yu Fujita, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hiromichi Hara, Tsukasa Kadota, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hirofumi Utsumi, Hiroshi Wakui, Jun Kojima, Takanori Numata, Yumi Kaneko

Source: Respiratory Research; 8/30/2016, Vol. 17, p1-12, 12p, 1 Diagram, 5 Graphs

Subject Terms: METFORMIN, IDIOPATHIC pulmonary fibrosis, NADPH oxidase, MYOFIBROBLASTS, TRANSFORMING growth factors-beta, REACTIVE oxygen species

Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis.

Authors: Kenji Kobayashi, Jun Araya, Shunsuke Minagawa, Hiromichi Hara, Nayuta Saito, Tsukasa Kadota, Nahoko Sato, Masahiro Yoshida, Kazuya Tsubouchi, Yusuke Kurita, Saburo Ito, Yu Fujita, Naoki Takasaka, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Jun Kojima, Kenichiro Shimizu, Takanori Numata

Source: Journal of Immunology; 7/15/2016, Vol. 197 Issue 2, p504-516, 13p

TGF-ß-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease.

Authors: Mitsuo Hashimoto¹, Haruhiko Yanagisawa¹, Shunsuke Minagawa¹, Debasish Sen¹, Royce Ma¹, Murray, Lynne A.², Ping Tsui², Jianlong Lou³, Marks, James D.³, Baron, Jody L.⁴, Krummel, Matthew F.¹, Nishimura, Stephen L.¹ stephen.nishimura@ucsf.edu

Source: Journal of Immunology. 8/1/2015, Vol. 195 Issue 3, p1182-1190. 9p.

Subject Terms: *TRANSFORMING growth factors, *CHEMOKINES, *DENDRITIC cells, *TOLL-like receptors, *IMMUNE response, *OBSTRUCTIVE lung disease treatment, *FIBROBLASTS, *LABORATORY mice

A Critical Role for Dendritic Cells in the Evolution of IL-1β-Mediated Murine Airway Disease.

Authors: Mitsuo Hashimoto¹, Haruhiko Yanagisawa¹, Shunsuke Minagawa¹, Sen, Debasish¹, Goodsell, Amanda², Ma, Royce¹, Moermans, Catherine¹, McKnelly, Kate J.¹, Baron, Jody L.², Krummel, Matthew F.¹, Nishimura, Stephen L.¹ stephen.nishimura@ucsf.edu

Source: Journal of Immunology. 4/15/2015, Vol. 194 Issue 8, p3962-3969. 8p.

Subject Terms: *TREATMENT of respiratory obstructions, *ANIMAL models of inflammation, *INTERLEUKIN-1, *DENDRITIC cells, *CHEMOKINE receptors