Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa

Authors: Miranda L. Scalabrino, Mishek Thapa, Tian Wang, Alapakkam P. Sampath, Jeannie Chen, Greg D. Field

Source: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/1aa9987457344b90b4f65e7efd14f6ff

Tissue-Dependent Expression and Translation of Circular RNAs with Recombinant AAV Vectors In Vivo

Authors: Rita M. Meganck, Erin K. Borchardt, Ruth M. Castellanos Rivera, Miranda L. Scalabrino, Jeremy E. Wilusz, William F. Marzluff, Aravind Asokan

Source: Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 89-98 (2018)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253118302208; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/4b05f58b76984d22b571558cdd5de463

Novel Methodology for Creating Macaque Retinas with Sortable Photoreceptors and Ganglion Cells

Authors: Shreyasi Choudhury, Christianne E Strang, John J. Alexander, Miranda L. Scalabrino, Julie Lynch Hill, Daniel T. Kasuga, C. Douglas Witherspoon, Sanford L. Boye, Paul D. Gamlin, Shannon Elizabeth Boye

Source: Frontiers in Neuroscience, Vol 10 (2016)

Subject Terms: macaque, subretinal injection, retinal ganglion cells (RGCs), adeno associated virus (AAV), photoreceptors (PRs), lateral geniculate nuclei (LGN) injection, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00551/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/b30c8f83196a4880bb93652e93d7b597

Robust cone-mediated signaling persists late into rod photoreceptor degeneration

Authors: Miranda L Scalabrino, Mishek Thapa, Lindsey A Chew, Esther Zhang, Jason Xu, Alapakkam P Sampath, Jeannie Chen, Greg D Field

Source: eLife, Vol 11 (2022)

Subject Terms: retina, vision, retinal ganglion cell, retinitis pigmentosa, cyclic nucleotide gated channel, bipolar cell, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/80271; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/11077c6101994e839c93bc8cf9c3b56d