Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis

Authors: Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Yufei Shi

Source: Frontiers in Endocrinology, Vol 16 (2025)

Subject Terms: CD274 (PD-L1), TBXAS1, MERTK, IL6, thyroid cancer metastasis, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2025.1514264/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/73526e1f349c4953a1d6936ef3506aa9

β-catenin attenuation leads to up-regulation of activating NKG2D ligands and tumor regression in BrafV600E-driven thyroid cancer cells

Authors: Minjing Zou, Suhad Al-Yahya, Monther Al-Alwan, Huda A. BinEssa, Khalid S. A. Khabar, Falah Almohanna, Abdullah M. Assiri, Abdulmohsen Altaweel, Amal Qattan, Brian F. Meyer, Ali S. Alzahrani, Yufei Shi

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: β-catenin, CTNNB1, BRAFV600E, NKG2D ligands, NK cells, thyroid cancer, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1171816/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/04631e41d80f49b3a9a9b059ef74c4bf

Mutation spectrum of EXT1 and EXT2 in the Saudi patients with hereditary multiple exostoses

Authors: Zayed Al-Zayed, Roua A. Al-Rijjal, Lamya Al-Ghofaili, Huda A. BinEssa, Rajeev Pant, Anwar Alrabiah, Thamer Al-Hussainan, Minjing Zou, Brian F. Meyer, Yufei Shi

Source: Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-11 (2021)

Subject Terms: EXT1, EXT12, Mutation, Exostoses, Osteochondromas, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1172

Access URL: https://doaj.org/article/e244caec184d480a9e099b3967d703d4

Molecular Analysis of CYP27B1 Mutations in Vitamin D-Dependent Rickets Type 1A: c.590G > A (p.G197D) Missense Mutation Causes a RNA Splicing Error

Authors: Minjing Zou, Ayla Guven, Huda A. BinEssa, Roua A. Al-Rijjal, Brian F. Meyer, Ali S. Alzahrani, Yufei Shi

Source: Frontiers in Genetics, Vol 11 (2020)

Subject Terms: CYP27B1 mutation, 1α-hydroxylase, vitamin D, rickets, RNA splicing, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2020.607517/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/b792308a71e44599aebd3189940ee874

Phenotype heterogeneity of congenital adrenal hyperplasia due to genetic mosaicism and concomitant nephrogenic diabetes insipidus in a sibling

Authors: Yılmaz Kor, Minjing Zou, Roua A. Al-Rijjal, Dorota Monies, Brian F. Meyer, Yufei Shi

Source: BMC Medical Genetics, Vol 19, Iss 1, Pp 1-7 (2018)

Subject Terms: 21-hydroxylase deficiency, Mosaicism, Nephrogenic diabetes insipidus, CYP21A2, AQP2, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12881-018-0629-2; https://doaj.org/toc/1471-2350

Access URL: https://doaj.org/article/8c28bf12c73a48cd959251e1829c267f

Clinical and genetic characteristics of 15 families with hereditary hypophosphatemia: Novel Mutations in PHEX and SLC34A3.

Authors: Sezer Acar, Huda A BinEssa, Korcan Demir, Roua A Al-Rijjal, Minjing Zou, Gönül Çatli, Ahmet Anık, Anwar F Al-Enezi, Seçil Özışık, Manar S A Al-Faham, Ayhan Abacı, Bumin Dündar, Walaa E Kattan, Maysoon Alsagob, Salih Kavukçu, Hamdi E Tamimi, Brian F Meyer, Ece Böber, Yufei Shi

Source: PLoS ONE, Vol 13, Iss 3, p e0193388 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5837132?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/10b254c616884e3f832371affc2506e0

Oncogenic Activation of MAP Kinase by BRAF Pseudogene in Thyroid Tumors

Authors: Minjing Zou, Essa Y. Baitei, Ali S. Alzahrani, Futwan Al-Mohanna, Nadir R. Farid, Brian Meyer, Yufei Shi

Source: Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 1, Pp 57-65 (2009)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558609800894; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/f343d40c1dfe4a64bb00c68bd26522b8

Novel CYP27B1 Gene Mutations in Patients with Vitamin D-Dependent Rickets Type 1A.

Authors: Korcan Demir, Walaa E Kattan, Minjing Zou, Erdem Durmaz, Huda BinEssa, Özlem Nalbantoğlu, Roua A Al-Rijjal, Brian Meyer, Behzat Özkan, Yufei Shi

Source: PLoS ONE, Vol 10, Iss 7, p e0131376 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4489500?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e3903ac1b8b24c278d67482cbfa3e096

A Novel Mutation in the CYP11B1 Gene Causes Steroid 11β-Hydroxylase Deficient Congenital Adrenal Hyperplasia with Reversible Cardiomyopathy

Authors: Mohammad A. Alqahtani, Ayed A. Shati, Minjing Zou, Ali M. Alsuheel, Abdullah A. Alhayani, Saleh M. Al-Qahtani, Hessa M. Gilban, Brain F. Meyer, Yufei Shi

Source: International Journal of Endocrinology, Vol 2015 (2015)

Subject Terms: Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://doaj.org/toc/1687-8337; https://doaj.org/toc/1687-8345

Access URL: https://doaj.org/article/f6789759e2874903a43b3c8cf939d15c

β-catenin attenuation leads to up-regulation of activating NKG2D ligands and tumor regression in Braf^V600E-driven thyroid cancer cells.

Authors: Minjing Zou, Al-Yahya, Suhad, Al-Alwan, Monther, BinEssa, Huda A., Khabar, Khalid S. A., Almohanna, Falah, Assiri, Abdullah M., Altaweel, Abdulmohsen, Qattan, Amal, Meyer, Brian F., Alzahrani, Ali S., Yufei Shi

Source: Frontiers in Immunology; 2023, p1-10, 10p

Subject Terms: CANCER cells, LIGANDS (Biochemistry), CELL-mediated cytotoxicity, THYROID cancer, WNT signal transduction, TUMOR growth

Insights of Noncanonical Splice-site Variants on RNA Splicing in Patients With Congenital Hypothyroidism.

Authors: Albader, Najla, Minjing Zou, BinEssa, Huda A., Abdi, Saba, Al-Enezi, Anwar F., Meyer, Brian F., Alzahrani, Ali S., Shi, Yufei

Source: Journal of Clinical Endocrinology & Metabolism; Mar2022, Vol. 107 Issue 3, pe12263-e1276, 14p

Subject Terms: CONGENITAL hypothyroidism, RNA regulation

Gene Therapy of Anaplastic Thyroid Carcinoma with a Single-Chain Interleukin-12 Fusion Protein.

Authors: Yufei Shi, Ranjit S. Parhar, Minjing Zou, Essa Baitei, George Kessie, Nadir R. Farid, Ali Alzahrani, Futwan A. Al-Mohanna

Source: Human Gene Therapy; 12/10/2003, Vol. 14 Issue 18, p1741-1751, 11p

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