Neonatal infection with Bordetella pertussis promotes autism-like phenotypes in mice

Authors: O’Neill, Eoin ^{1, 2}, Curham, Lucy ¹, Ní Chasaide, Caitlín ¹, O’Brien, Síofra ¹, McManus, Gavin ¹, Moran, Barry ¹, Rubin, Keith ³, Glazer, Steven ³, Lynch, Marina A. ^{2, 4}, Mills, Kingston H.G. ^{1, 4, 5, ∗}

Source: In iScience 17 January 2025 28(1)

A novel whole blood assay to quantify the release of T cell associated cytokines in response to Bordetella pertussis antigens

Authors: Diavatopoulos, Dimitri A., Mills, Kingston H.G., Kester, Kent E., Kampmann, Beate, Silerova, Marcela, Heininger, Ulrich, van Dongen, Jacques J.M., van der Most, Robbert G., Huijnen, Martijn A., Siena, Emilio, Mielcarek, Nathalie, Ochs, Martina M., Denoël, Philippe, Berbers, Guy, Buisman, Annemarie M., de Jonge, Marien I., Fenwick, Craig, Gorringe, Andrew, He, Qiushui, Kelly, Dominic, Le Grand, Roger, Locht, Camille, Mascart, Françoise, Mertsola, Jussi, Orfao, Alberto, Pantaleo, Giuseppe, Pollard, Andrew J., Preston, Andrew, Read, Robert, Sebo, Peter, van Els, Cecile, Vecerek, Branislav, Londoño-Hayes, Patricia, de Groot, Ronald, Pinto, Marta Valente, Barkoff, Alex-Mikael, Bibi, Sagida, Knuutila, Aapo, Teräsjärvi, Johanna, Clutterbuck, Elizabeth, Gimenez-Fourage, Sophie, Pagnon, Anke, van Gaans-van den Brink, Jacqueline A.M., Corbiere, Veronique, De Montfort, Aymeric, Saso, Anja, Jobe, Haddijatou, Roetynck, Sophie, Simonetti, Elles, Diavatopoulos, Dimitri, Lambert, Eleonora E., Blanc, Pascal, van Els, Cécile A.C.M.

Source: In Journal of Immunological Methods November 2024 534

Nasal vaccines for pertussis

Authors: Schmitt, Pauline ^*, Borkner, Lisa ^*, Jazayeri, Seyed Davoud ^*, McCarthy, Karen N ^*, Mills, Kingston HG

Source: In Current Opinion in Immunology October 2023 84

PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection

Authors: Baran, Marcin, Feriotti, Claudia, McGinley, Aoife, Carlile, Simon R., Jiang, Zhaozhao, Calderon-Gonzalez, Ricardo, Dumigan, Amy, Sá-Pessoa, Joana, Sutton, Caroline E., Kearney, Jay, McLoughlin, Rachel M., Mills, Kingston H.G., Fitzgerald, Katherine A., Bengeochea, Jose A., Bowie, Andrew G.

Source: In Cell Reports 25 April 2023 42(4)

Sex differences regulate immune responses in experimental autoimmune encephalomyelitis and multiple sclerosis

Authors: Ryan, Lucy, Mills, Kingston H. G.

Source: European journal of immunology. 52(1):24-33

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100143354961.0x000001&indx=1&recIds=ETOCvdc_100143354961.0x000001

Modulation of haematopoiesis by protozoal and helminth parasites.

Authors: Cunningham, Kyle T.¹ (AUTHOR), Mills, Kingston H. G.² (AUTHOR) kingston.mills@tcd.ie

Source: Parasite Immunology. Dec2023, Vol. 45 Issue 12, p1-10. 10p.

Subject Terms: *HEMATOPOIESIS, *PARASITES, *HEMATOPOIETIC stem cells, *PROTOZOAN diseases, *MYELOID cells, *BONE marrow

IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils

Authors: Borkner, Lisa, Curham, Lucy M., Wilk, Mieszko M., Moran, Barry, Mills, Kingston H.G.

Source: In Mucosal Immunology September 2021 14(5):1183-1202

Extracellular matrix scaffolds derived from different musculoskeletal tissues drive distinct macrophage phenotypes and direct tissue-specific cellular differentiation

Authors: Mahon, Olwyn R., Browe, David C., Diaz-Payno, Pedro J., Pitacco, Pierluca, Cunningham, Kyle T., Mills, Kingston H.G., Dunne, Aisling, Kelly, Daniel J.

Source: In Journal of Immunology and Regenerative Medicine May 2021 12

Helminth Imprinting of Hematopoietic Stem Cells Sustains Anti-Inflammatory Trained Innate Immunity That Attenuates Autoimmune Disease

Authors: Cunningham, Kyle T., Finlay, Conor M., Mills, Kingston H. G.

Source: Journal of immunology. 206(7):1618-1630

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626193017&indx=1&recIds=ETOCRN626193017

Trained Innate Immunity in Hematopoietic Stem Cell and Solid Organ Transplantation

Authors: Cunningham, Kyle T., Mills, Kingston H.G.

Source: Transplantation. 105(8):1666-1676

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184648571.0x000001&indx=1&recIds=ETOCvdc_100184648571.0x000001

PD‐1 regulation of pathogenic IL‐17‐secreting γδ T cells in experimental autoimmune encephalomyelitis.

Authors: Leane, Charlotte M., Sutton, Caroline E., Moran, Barry, Mills, Kingston H.G.

Source: European Journal of Immunology; Oct2024, Vol. 54 Issue 10, p1-12, 12p

Subject Terms: REGULATORY T cells, T helper cells, T cells, IMMUNE checkpoint inhibitors, IMMUNE checkpoint proteins

Exercise-induced re-programming of age-related metabolic changes in microglia is accompanied by a reduction in senescent cells

Authors: Mela, Virginia, Mota, Bibiana C., Milner, Mark, McGinley, Aoife, Mills, Kingston H.G., Kelly, Áine M, Lynch, Marina A.

Source: In Brain Behavior and Immunity July 2020 87:413-428

Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner

Authors: Mahon, Olwyn R., Browe, David C., Gonzalez-Fernandez, Tomas, Pitacco, Pierluca, Whelan, Ian T., Von Euw, Stanislas, Hobbs, Christopher, Nicolosi, Valeria, Cunningham, Kyle T., Mills, Kingston H.G., Kelly, Daniel J., Dunne, Aisling

Source: In Biomaterials May 2020 239

Bystander activation of Bordetella pertussis‐induced nasal tissue‐resident memory CD4 T cells confers heterologous immunity to Klebsiella pneumoniae

Authors: Curham, Lucy M., Mannion, Jenny M., Daly, Clíodhna M., Wilk, Mieszko M., Borkner, Lisa, Lalor, Stephen J., McLoughlin, Rachel M., Mills, Kingston H.G.

Source: European journal of immunology. 53(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185320318.0x000001&indx=1&recIds=ETOCvdc_100185320318.0x000001

Innate lymphoid cells recruit T cells to turn up the heat on tumors

Authors: Mills, Kingston H.G.

Source: Cancer cell. 40(4):362-364

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100160341352.0x000001&indx=1&recIds=ETOCvdc_100160341352.0x000001

Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells

Authors: McGinley, Aoife M., Sutton, Caroline E., Edwards, Sarah C., Leane, Charlotte M., DeCourcey, Joseph, Teijeiro, Ana, Hamilton, John A., Boon, Louis, Djouder, Nabil, Mills, Kingston H.G.

Source: In Immunity 18 February 2020 52(2):342-356

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

Authors: Angiari, Stefano, Runtsch, Marah C., Sutton, Caroline E., Palsson-McDermott, Eva M., Kelly, Beth, Rana, Nisha, Kane, Harry, Papadopoulou, Gina, Pearce, Erika L., Mills, Kingston H.G., O'Neill, Luke A.J.

Source: In Cell Metabolism 4 February 2020 31(2):391-405

Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation

Authors: Hughes, Mark M., Hooftman, Alexander, Angiari, Stefano, Tummala, Padmaja, Zaslona, Zbigniew, Runtsch, Marah C., McGettrick, Anne F., Sutton, Caroline E., Diskin, Ciana, Rooke, Melissa, Takahashi, Shuhei, Sundararaj, Srinivasan, Casarotto, Marco G., Dahlstrom, Jane E., Palsson-McDermott, Eva M., Corr, Sinead C., Mills, Kingston H.G., Preston, Roger J.S., Neamati, Nouri, Xie, Yiyue, Baell, Jonathan B., Board, Philip G., O’Neill, Luke A.J.

Source: In Cell Reports 1 October 2019 29(1):151-161

PERISCOPE: road towards effective control of pertussis

Authors: Diavatopoulos, Dimitri A., Mills, Kingston H.G., Kester, Kent E., Kampmann, Beate, Silerova, Marcela, Heininger, Ulrich, van Dongen, Jacques J.M., van der Most, Robbert G., Huijnen, Martijn A., Siena, Emilio, Mielcarek, Nathalie, Ochs, Martina M., Denoël, Philippe, Berbers, Guy, Buisman, Annemarie M., de Jonge, Marien I., Fenwick, Craig, Gorringe, Andrew, He, Qiushui, Kelly, Dominic, Le Grand, Roger, Locht, Camille, Mascart, Françoise, Mertsola, Jussi, Orfao, Alberto, Pantaleo, Giuseppe, Pollard, Andrew J., Preston, Andrew, Read, Robert, Sebo, Peter, van Els, Cecile, Vecerek, Branislav, Londoño-Hayes, Patricia, de Groot, Ronald

Source: In The Lancet Infectious Diseases May 2019 19(5):e179-e186

IL-33—Stimulated Murine Mast Cells Polarize Alternatively Activated Macrophages, Which Suppress T Cells That Mediate Experimental Autoimmune Encephalomyelitis

Authors: Finlay, Conor M., Cunningham, Kyle T., Doyle, Benjamin, Mills, Kingston H. G.

Source: Journal of immunology. 205(7):1909-1919

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624837020&indx=1&recIds=ETOCRN624837020