Inhibition of hepatic p63 ameliorates steatohepatitis with fibrosis in mice

Authors: Marcos F. Fondevila, Eva Novoa, Uxia Fernandez, Valentina Dorta, Tamara Parracho, Henriette Kreimeyer, Maria Garcia-Vence, Maria P. Chantada-Vazquez, Susana B. Bravo, Begoña Porteiro, Alba Cabaleiro, Mijra Koning, Ana Senra, Yara Souto, Joanne Verheij, Diana Guallar, Miguel Fidalgo, Abraham S. Meijnikman, Natalia da Silva Lima, Carlos Dieguez, Maria J. Gonzalez-Rellan, Ruben Nogueiras

Source: Molecular Metabolism, Vol 85, Iss , Pp 101962- (2024)

Subject Terms: p63, TAp63, MASLD, NAFLD, MASH, NASH, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877824000930; https://doaj.org/toc/2212-8778

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Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function

Authors: Maria J. Gonzalez-Rellan, Tamara Parracho, Violeta Heras, Amaia Rodriguez, Marcos F. Fondevila, Eva Novoa, Natalia Lima, Marta Varela-Rey, Ana Senra, Maria D.P. Chantada-Vazquez, Cristina Ameneiro, Ganeko Bernardo, David Fernandez-Ramos, Fernando Lopitz-Otsoa, Jon Bilbao, Diana Guallar, Miguel Fidalgo, Susana Bravo, Carlos Dieguez, Maria L. Martinez-Chantar, Oscar Millet, Jose M. Mato, Markus Schwaninger, Vincent Prevot, Javier Crespo, Gema Frühbeck, Paula Iruzubieta, Ruben Nogueiras

Source: Molecular Metabolism, Vol 75, Iss , Pp 101776- (2023)

Subject Terms: O-GlcNAcylation, Mitochondrial dysfunction, NAFLD, Internal medicine, RC31-1245

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Relation: http://www.sciencedirect.com/science/article/pii/S2212877823001102; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/534b9501b49e4a008f0846e144ff4da3

O-GlcNAcylated p53 in the liver modulates hepatic glucose production

Authors: Maria J. Gonzalez-Rellan, Marcos F. Fondevila, Uxia Fernandez, Amaia Rodríguez, Marta Varela-Rey, Christelle Veyrat-Durebex, Samuel Seoane, Ganeko Bernardo, Fernando Lopitz-Otsoa, David Fernández-Ramos, Jon Bilbao, Cristina Iglesias, Eva Novoa, Cristina Ameneiro, Ana Senra, Daniel Beiroa, Juan Cuñarro, Maria DP Chantada-Vazquez, Maria Garcia-Vence, Susana B. Bravo, Natalia Da Silva Lima, Begoña Porteiro, Carmen Carneiro, Anxo Vidal, Sulay Tovar, Timo D. Müller, Johan Ferno, Diana Guallar, Miguel Fidalgo, Guadalupe Sabio, Stephan Herzig, Won Ho Yang, Jin Won Cho, Maria Luz Martinez-Chantar, Roman Perez-Fernandez, Miguel López, Carlos Dieguez, Jose M. Mato, Oscar Millet, Roberto Coppari, Ashwin Woodhoo, Gema Fruhbeck, Ruben Nogueiras

Source: Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/9769f87dfa1c4d5b90bfa5688f97fb4c

Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation

Authors: Jie Lan, Nicholas Rajan, Martin Bizet, Audrey Penning, Nitesh K. Singh, Diana Guallar, Emilie Calonne, Andrea Li Greci, Elise Bonvin, Rachel Deplus, Phillip J. Hsu, Sigrid Nachtergaele, Chengjie Ma, Renhua Song, Alejandro Fuentes-Iglesias, Bouchra Hassabi, Pascale Putmans, Frédérique Mies, Gerben Menschaert, Justin J. L. Wong, Jianlong Wang, Miguel Fidalgo, Bifeng Yuan, François Fuks

Source: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/9305faa1ca904cdba667b6f5f1a6c75f

Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development

Authors: Andrew J. Woo, Chelsea-Ann A. Patry, Alireza Ghamari, Gabriela Pregernig, Daniel Yuan, Kangni Zheng, Taylor Piers, Moira Hibbs, Ji Li, Miguel Fidalgo, Jenny Y. Wang, Joo-Hyeon Lee, Peter J. Leedman, Jianlong Wang, Ernest Fraenkel, Alan B. Cantor

Source: Blood Advances, Vol 3, Iss 16, Pp 2499-2511 (2019)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S247395292030032X; https://doaj.org/toc/2473-9529

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The Complexity of TET2 Functions in Pluripotency and Development

Authors: Vera Garcia-Outeiral, Cristina de la Parte, Miguel Fidalgo, Diana Guallar

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2021)

Subject Terms: TET2, epigenetic, epitranscriptomic, pluripotency, reprogramming, development, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.630754/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/fb60a33089d54f29b3d95b797fd394ef

An Optimized Immunoprecipitation Protocol for Assessing Protein-RNA Interactions In Vitro

Authors: Alejandro Fuentes-Iglesias, Vera Garcia-Outeiral, Jose Angel Pardavila, Jianlong Wang, Miguel Fidalgo, Diana Guallar

Source: STAR Protocols, Vol 1, Iss 2, Pp 100093- (2020)

Subject Terms: Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166720300800; https://doaj.org/toc/2666-1667

Access URL: https://doaj.org/article/66f87f956af94b8b81d07f6132fadaeb

YY1 Positively Regulates Transcription by Targeting Promoters and Super-Enhancers through the BAF Complex in Embryonic Stem Cells

Authors: Jia Wang, Xingui Wu, Chao Wei, Xin Huang, Qian Ma, Xiaona Huang, Francesco Faiola, Diana Guallar, Miguel Fidalgo, Tingyuan Huang, Di Peng, Li Chen, Haopeng Yu, Xingyu Li, Junyi Sun, Xinyi Liu, Xiaoxia Cai, Xiao Chen, Ling Wang, Jian Ren, Jianlong Wang, Junjun Ding

Source: Stem Cell Reports, Vol 10, Iss 4, Pp 1324-1339 (2018)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221367111830095X; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/be6237668ab74a6e87f58fac11272bf9

NAC1 Regulates Somatic Cell Reprogramming by Controlling Zeb1 and E-cadherin Expression

Authors: Francesco Faiola, Nuoya Yin, Miguel Fidalgo, Xin Huang, Arven Saunders, Junjun Ding, Diana Guallar, Baoyen Dang, Jianlong Wang

Source: Stem Cell Reports, Vol 9, Iss 3, Pp 913-926 (2017)

Subject Terms: NAC1/BTBD14B, iPSC, E-cadherin, Zeb1, miR-200, Nanog, pluripotency, reprogramming, mesenchymal-to-epithelial transition, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671117303119; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/2b06d1e976e64cb7846deebf69fbcf36

Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming

Authors: Arven Saunders, Dan Li, Francesco Faiola, Xin Huang, Miguel Fidalgo, Diana Guallar, Junjun Ding, Fan Yang, Yang Xu, Hongwei Zhou, Jianlong Wang

Source: Stem Cell Reports, Vol 8, Iss 5, Pp 1115-1123 (2017)

Subject Terms: post-translational modification, self-renewal, iPSC, phospho-NANOG, serine to alanine mutation, pluripotency, reprogramming, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671117301297; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/45aebde53d754d6ba516e3f2c5ccc7e2

The SIN3A/HDAC Corepressor Complex Functionally Cooperates with NANOG to Promote Pluripotency

Authors: Arven Saunders, Xin Huang, Miguel Fidalgo, Michael H. Reimer, Jr., Francesco Faiola, Junjun Ding, Carlos Sánchez-Priego, Diana Guallar, Carmen Sáenz, Dan Li, Jianlong Wang

Source: Cell Reports, Vol 18, Iss 7, Pp 1713-1726 (2017)

Subject Terms: SIN3A, HDAC1, HDAC2, VPA, pre-iPSCs, iPSCs, EpiSCs, ESCs, SIN3B, TET1/2, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717301122; https://doaj.org/toc/2211-1247

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Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling

Authors: Xin Huang, Sophie Balmer, Fan Yang, Miguel Fidalgo, Dan Li, Diana Guallar, Anna-Katerina Hadjantonakis, Jianlong Wang

Source: eLife, Vol 6 (2017)

Subject Terms: mouse embryo, epiblast maturation, lineage commitment, nodal signaling, A-P patterning, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/33333; https://doaj.org/toc/2050-084X

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The Smithsons’ Unbuilt Projects: Considerations on the Retirement House Approach

Authors: João Miguel Fidalgo, Helder Casal Ribeiro

Source: Architecture, Vol 4, Iss 2, Pp 303-315 (2024)

Subject Terms: appliance houses, modernism, retirement house, Smithsons, Architecture, NA1-9428

File Description: electronic resource

Relation: https://www.mdpi.com/2673-8945/4/2/18; https://doaj.org/toc/2673-8945

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Assessment of natural variation in the first pore domain of the tomato HKT1;2 transporter and characterization of mutated versions of SlHKT1;2 expressed in Xenopus laevis oocytes and via complementation of the salt sensitive athkt1;1 mutant

Authors: Pedro Miguel Fidalgo De Almeida, Gert-Jan ede Boer, Albertus H de Boer

Source: Frontiers in Plant Science, Vol 5 (2014)

Subject Terms: Mutation, Tomato, natural variation, HKT1 genes, pore domain., Plant culture, SB1-1110

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Relation: http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00600/full; https://doaj.org/toc/1664-462X

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