KRAS-mutant non-small cell lung cancer (NSCLC) therapy based on tepotinib and omeprazole combination

Authors: Rafael Rosell, Eloisa Jantus-Lewintre, Peng Cao, Xueting Cai, Baojuan Xing, Masaoki Ito, Jose Luis Gomez-Vazquez, Mireia Marco-Jordán, Silvia Calabuig-Fariñas, Andrés Felipe Cardona, Jordi Codony-Servat, Jessica Gonzalez, Kevin València-Clua, Andrés Aguilar, Carlos Pedraz-Valdunciel, Zahra Dantes, Anisha Jain, S Chandan, Miguel Angel Molina-Vila, Oscar Arrieta, Macarena Ferrero, Carlos Camps, Maria González-Cao

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)

Subject Terms: Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/6654162f004044148f38c519b8f50a91

Fluorescence In Situ Hybridization (FISH) for the Characterization and Monitoring of Primary Cultures from Human Tumors

Authors: Ruth Román-Lladó, Cristina Aguado, Núria Jordana-Ariza, Jaume Roca-Arias, Sonia Rodríguez, Erika Aldeguer, Mónica Garzón-Ibañez, Beatriz García-Peláez, Marta Vives-Usano, Ana Giménez-Capitán, Andrés Aguilar, Alejandro Martinez-Bueno, María Gonzalez Cao, Florencia García-Casabal, Santiago Viteri, Clara Mayo de las Casas, Rafael Rosell, Miguel Angel Molina-Vila

Source: Journal of Molecular Pathology, Vol 4, Iss 1, Pp 57-68 (2023)

Subject Terms: primary culture, FISH, malignant effusions, malignant ascites, Pathology, RB1-214

File Description: electronic resource

Relation: https://www.mdpi.com/2673-5261/4/1/7; https://doaj.org/toc/2673-5261

Access URL: https://doaj.org/article/4aa6f599da1a468abb18119b19ad755f

Liquid biopsy in detecting early non-small cell lung cancer

Authors: Rafael Rosell, Mariacarmela Santarpia, Carlos Pedraz-Valdunciel, Giuliana Ciappina, Andrés Aguilar, Ana Giménez-Capitán, Masaoki Ito, Maria González-Cao, Miguel Angel Molina-Vila

Source: The Journal of Liquid Biopsy, Vol 1, Iss , Pp 100001- (2023)

Subject Terms: KRAS, Liquid biopsy, LKB1, Biomarkers, CircRNAs and NSCLC, Medicine

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950195423000012; https://doaj.org/toc/2950-1954

Access URL: https://doaj.org/article/96ec49e004614cbda975885f7d90575e

Digital multiplexed analysis of circular RNAs in FFPE and fresh non‐small cell lung cancer specimens

Authors: Carlos Pedraz‐Valdunciel, Stavros Giannoukakos, Nicolas Potie, Ana Giménez‐Capitán, Chung‐Ying Huang, Michael Hackenberg, Alberto Fernandez‐Hilario, Jill Bracht, Martyna Filipska, Erika Aldeguer, Sonia Rodríguez, Trever G. Bivona, Sarah Warren, Cristina Aguado, Masaoki Ito, Andrés Aguilar‐Hernández, Miguel Angel Molina‐Vila, Rafael Rosell

Source: Molecular Oncology, Vol 16, Iss 12, Pp 2367-2383 (2022)

Subject Terms: biomarkers, cancer, circRNA, diagnosis, nCounter, NSCLC, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/80cef2ed33524c79919697a56c94f2dd

Panels and models for accurate prediction of tumor mutation burden in tumor samples

Authors: Elizabeth Martínez-Pérez, Miguel Angel Molina-Vila, Cristina Marino-Buslje

Source: npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/1b76c4e637d44f018df09d860ec13ed7

Author Correction: BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer

Authors: Niki Karachaliou, Jordi Codony-Servat, Cristina Teixidó, Sara Pilotto, Ana Drozdowskyj, Carles Codony-Servat, Ana Giménez-Capitán, Miguel Angel Molina-Vila, Jordi Bertrán-Alamillo, Radj Gervais, Bartomeu Massuti, Teresa Morán, Margarita Majem, Enriqueta Felip, Enric Carcereny, Rosario García-Campelo, Santiago Viteri, María González-Cao, Daniela Morales-Espinosa, Alberto Verlicchi, Elisabetta Crisetti, Imane Chaib, Mariacarmela Santarpia, José Luis Ramírez, Joaquim Bosch-Barrera, Andrés Felipe Cardona, Filippo de Marinis, Guillermo López-Vivanco, José Miguel Sánchez, Alain Vergnenegre, José Javier Sánchez Hernández, Isabella Sperduti, Emilio Bria, Rafael Rosell

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/907f95952a6f451dab4695071025b8b3

Targeting PKCι-PAK1 signaling pathways in EGFR and KRAS mutant adenocarcinoma and lung squamous cell carcinoma

Authors: Masaoki Ito, Carles Codony-Servat, Jordi Codony-Servat, David Lligé, Imane Chaib, Xiaoyan Sun, Jing Miao, Rongwei Sun, Xueting Cai, Alberto Verlicchi, Morihito Okada, Miguel Angel Molina-Vila, Niki Karachaliou, Peng Cao, Rafael Rosell

Source: Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-11 (2019)

Subject Terms: Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12964-019-0446-z; https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/94f8d9791dfa43af80aa48a034d14714

BRCA1 Expression and Outcome in Patients With EGFR-Mutant NSCLC Treated With Gefitinib Alone or in Combination With Olaparib

Authors: Niki Karachaliou, MD, PhD, Oscar Arrieta, MD, Ana Giménez-Capitán, BSc, Erika Aldeguer, BSc, Ana Drozdowskyj, PhD, Imane Chaib, PhD, Noemí Reguart, MD, PhD, Rosario Garcia-Campelo, MD, Jing-Hua Chen, MD, Miguel Angel Molina-Vila, PhD, Rafael Rosell, MD, PhD

Source: JTO Clinical and Research Reports, Vol 2, Iss 3, Pp 100113- (2021)

Subject Terms: EGFR, Lung cancer, Gefitinib, Olaparib, GOAL study, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364320301594; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/08a2152e29af4e089606394482732718

Src-Homology 2 Domain-Containing Phosphatase 2 in Resected EGFR Mutation-Positive Lung Adenocarcinoma

Authors: Masaoki Ito, MD, Jordi Codony-Servat, PhD, Ana Giménez-Capitán, BSc, Mireia Serra-Mitjans, MD, Francisco Pérez-Ochoa, MD, David Llige, BSc, Imane Chaib, PhD, Ramón Rami-Porta, MD, Carme Obiols, MD, Sergi Call, MD, Manuela Iglesias, MD, José Belda-Sanchis, MD, Xavier Tarroch-Sarasa, MD, Niki Karachaliou, MD, Miguel Angel Molina-Vila, PhD, Morihito Okada, MD, Rafael Rosell, MD

Source: JTO Clinical and Research Reports, Vol 1, Iss 4, Pp 100084- (2020)

Subject Terms: Lung adenocarcinoma, EGFR, SHP2, Surgery, Recurrence, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364320301077; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/ba1595860e4f4a8a8b44fa1c6caeb13a

Precision medicine and its implementation in patients with NTRK fusion genes: perspective from developing countries

Authors: Andrés F. Cardona, Oscar Arrieta, Alejandro Ruiz-Patiño, Carolina Sotelo, Nataly Zamudio-Molano, Zyanya Lucia Zatarain-Barrón, Luisa Ricaurte, Luis Raez, Marco Polo Peralta Álvarez, Feliciano Barrón, Leonardo Rojas, Christian Rolfo, Niki Karachaliou, Miguel Angel Molina-Vila, Rafael Rosell

Source: Therapeutic Advances in Respiratory Disease, Vol 14 (2020)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1753-4666

Access URL: https://doaj.org/article/71577f0890384178a8c86f20101ad3f1

Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradationResearch in context

Authors: Yingyan Han, Peng Wu, Zhi Wang, Zeyu Zhang, Shujuan Sun, Jia Liu, Song Gong, Peipei Gao, Tomoo Iwakuma, Miguel Angel Molina-Vila, Benjamin Ping-Chi Chen, Yu Zhang, Teng Ji, Qingqing Mo, Pingbo Chen, Junbo Hu, Shixuan Wang, Jianfeng Zhou, Hua Lu, Qinglei Gao

Source: EBioMedicine, Vol 40, Iss , Pp 92-105 (2019)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396419300027; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/538606e3a04a433d81a758005934988d

Quantification and localization of oncogenic receptor tyrosine kinase variant transcripts using molecular inversion probes

Authors: Corina N. A. M. van den Heuvel, Arvid I. Das, Tessa de Bitter, Femke Simmer, Thomas Wurdinger, Miguel Angel Molina-Vila, William P. J. Leenders

Source: Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a96e3530439a41b7b9df6a5ba6233936

Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis

Authors: Niki Karachaliou, Imane Chaib, Andres Felipe Cardona, Jordi Berenguer, Jillian Wilhelmina Paulina Bracht, Jie Yang, Xueting Cai, Zhigang Wang, Chunping Hu, Ana Drozdowskyj, Carles Codony Servat, Jordi Codony Servat, Masaoki Ito, Ilaria Attili, Erika Aldeguer, Ana Gimenez Capitan, July Rodriguez, Leonardo Rojas, Santiago Viteri, Miguel Angel Molina-Vila, Sai-Hong Ignatius Ou, Morihito Okada, Tony S. Mok, Trever G. Bivona, Mayumi Ono, Jean Cui, Santiago Ramón y Cajal, Peng Cao, Rafael Rosell

Source: EBioMedicine, Vol 29, Iss , Pp 112-127 (2018)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396418300501; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/d4a85629cde14b10a642cf79a55d7f2c

Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts

Authors: David Carbone, Michael Sharpnack, Kai He, Lisa H. Butterfield, Alexander M. M. Eggermont, Maria Gonzalez-Cao, Niki Karachaliou, Guillermo Crespo, Erika Aldeguer, Ana Drozdowskyj, Ana Giménez-Capitán, Cristina Teixidó, Miguel Angel Molina-Vila, Santiago Viteri Ramírez, Salvador Martin Algarra, Elisabeth Pérez-Ruiz, Iván Márquez-Rodas, Delvys Rodriguez-Abreu, Remei Blanco, Teresa Puértolas, Maria Angeles Royo, Rafael Rosell, Maria Libera Ascierto, Svetlana Hamm, Tanja Wulff, Kerstin Kronthaler, Sabine Schrepfer, Ulrike Parnitzke, Anne Catherine Bretz, Roland Baumgartner, Veronica Ferrucci, Francesco Paolo Pennino, Luisa Dassi, Fatemeh Asadzadeh, Roberto Siciliano, Marianeve Carotenuto, Daniela Spano, Cristina Maria Chiarolla, Adelaide Greco, Monica Cantile, Maurizio Di Bonito, Gerardo Botti, Vandenbussche Jonathan, Gevaert Kris, Massimo Zollo, Teresa Amaral, Ioanna Tampouri, Ulrike Keim, Thomas Eigentler, Claus Garbe, Andrea Forschner, Alessandra Cesano, Sarah Warren, Duane Moogk, Kaitao Li, Zhou Yuan, Shi Zhong, Zhiya Yu, Ivan Liadi, William Rittase, Victoria Fang, Janna Dougherty, Arianne Perez-Garcia, Iman Osman, Navin Varadarajan, Nicholas P. Restifo, Alan Frey, Cheng Zhu, Michelle Krogsgaard, Claire Vanpouille-Box, Silvia C. Formenti, Sandra Demaria, Cristiana Lo Nigro, Alexander Renziehausen, Andreas G. Tzakos, Hexiao Wang, Bhavya Rao, Rubeta Matin, Catherine Harwood, Daniela Vivenza, Federica Tonissi, Marcella Occelli, Lynda Weir, Su Li, Van Ren Sim, Kevin O’Neill, Alan Evans, Alastair Thompson, Peter Szlosarek, Colin Fleming, Charlotte Proby, Nelofer Syed, Marco Merlano, Tim Crook, Robert Ferguson, Danny Simpson, Carlos Martinez, Matjaz Vogelsang, Esther Kazlow, Melissa Wilson, Anna Pavlick, Jeffrey Weber, Ryan Sullivan, Keith Flaherty, Antoni Ribas, Tomas Kirchhoff, Antonio D’Avino, Licia Guida, Augusto Cosacco, Roberta D’Aniello, Piera Maiolino, Teresa Tramontano, Maria R. Sarno, Ida Palazzo, Angela Di Napoli, Gianclaudio Acunzo, Mariarosanna De Fina, Antonia Silvestri, Monica Specchia, Michela Musacchio, Gianfranco Giglio, Francesco Carrozza, Liberato Di Lullo, Gian Marco De Maddi, Adele Venturelli, Elisabetta Gambale, Alessia Gatta, Davide Brocco, Consiglia Carella, Michele De Tursi, Thomas F. Gajewski, Costanza M. Cristiani, Rossana Tallerico, Valeria Ventura, Mariaelena Capone, Gabriele Madonna, Domenico Mallardo, Eliska Selinger, Cinzia Garofalo, Elina Staaf, Ester Simeone, Antonio M. Grimaldi, Genny del Zotto, Elio Gulletta, Gennaro Ciliberto, Alessandro Moretta, Paolo A. Ascierto, Ennio Carbone, Susan Costantini, Angela Sorice, Francesca Capone, Alfredo Budillon, Carolina Cauchi, Grazia Sciancalepore, Michela Rovera, Chiara Varamo, Zelda Seia, Stefania Palazzini, Fabiana Errico, Davide Basso, Laura Quaranta, Giuseppe Forte, Fulvio Lavagna, Silvia Violante, Paolo Bosio, Laura Lattanzio, Marco C Merlano, Mike Gowen, Jeremy Tchack, Hua Zhou, Keith Giles, Scott Paschke, Una Moran, David Fenyo, Aris Tsirigos, Michael Pacold, Silvana Morello, Claudia Sorrentino, Diana Giannarelli, Aldo Pinto, Federica Fratangelo, Rosaria Falcone, Vito Vanella, Dirk Schadendorf, Karl Lewis, Michele Maio, Lev Demidov, Mario Mandalà, Igor Bondarenko, Christopher Herbert, Andrzej Mackiewicz, Piotr Rutkowski, Alexander Guminski, Grant Goodman, Brian Simmons, Chenglin Ye, Gregory Hooper, Matthew J. Wongchenko, Yibing Yan, Frank Hermann, Astrid Ammendola, René Bartz, Bulotta Alessandra, Colombo Letizia, Mirabile Aurora, Lazzari Chiara, Mercuri Santo Raffaele, Parolini Danilo, Rizzo Nathalie, Martella Stefano, Modorati Giulio, Brianti Pina, Cestone Enza, Bellinzona Federica, Miserocchi Elisabetta, Gianni Luca, Gregorc Vanesa, Sanjiv Agarwala, B. Mark Smithers, Axel Haushild, Eric Watcher, Luigi Fattore, Ciro Francesco Ruggiero, Domenico Liguoro, Andrea Cerri, Maria Elena Pisanu, Rita Mancini

Source: Journal of Translational Medicine, Vol 16, Iss S1, Pp 1-15 (2018)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12967-017-1352-z; https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/38353f48461f433683ce99cbc35a515e

Interferon gamma, an important marker of response to immune checkpoint blockade in non-small cell lung cancer and melanoma patients

Authors: Niki Karachaliou, Maria Gonzalez-Cao, Guillermo Crespo, Ana Drozdowskyj, Erika Aldeguer, Ana Gimenez-Capitan, Cristina Teixido, Miguel Angel Molina-Vila, Santiago Viteri, Maria De Los Llanos Gil, Salvador Martin Algarra, Elisabeth Perez-Ruiz, Ivan Marquez-Rodas, Delvys Rodriguez-Abreu, Remedios Blanco, Teresa Puertolas, Maria Angeles Royo, Rafael Rosell

Source: Therapeutic Advances in Medical Oncology, Vol 10 (2018)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/8ac2c8fef28b486789e2a6c0357c1a10

Pangaea Oncology, Dexeus University Hospital: bridging preclinical and clinical research

Authors: María González-Cao, Carlos Pedraz, Miguel Ángel Molina-Vila, Rafael Rosell

Source: Molecular Cancer, Vol 23, Iss 1, Pp 1-3 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/a71637a762b04bf3be25a17680e25ef7

Vaccine antibodies against a synthetic epidermal growth factor variant enhance the antitumor effects of inhibitors targeting the MAPK/ERK and PI3K/Akt pathways

Authors: Silvia García-Roman, Mónica Garzón-Ibáñez, Jordi Bertrán-Alamillo, Núria Jordana-Ariza, Ana Giménez-Capitán, Beatriz García-Peláez, Marta Vives-Usano, Jordi Codony-Servat, Erik d'Hondt, Rafael Rosell, Miguel Ángel Molina-Vila

Source: Translational Oncology, Vol 40, Iss , Pp 101878- (2024)

Subject Terms: EGF, Vaccine, Inhibitors, Akt, ERK, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523324000044; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/fc3b1c5adf764070ae7e5f5cd5f1ee1a

Brief Report: circRUNX1 as Potential Biomarker for Cancer Recurrence in EGFR Mutation-Positive Surgically Resected NSCLC

Authors: Carlos Pedraz-Valdunciel, PhD, Masaoki Ito, MD, Stavros Giannoukakos, PhD student, Ana Giménez-Capitán, MSc, Miguel Ángel Molina-Vila, PhD, Rafael Rosell, MD, PhD

Source: JTO Clinical and Research Reports, Vol 4, Iss 12, Pp 100604- (2023)

Subject Terms: CircRUNX1, Biomarker, EGFR mutation, NSCLC, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364323001479; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/d9bf3f77370d44da9f2f5fc06d7d9205

Overcoming MET-mediated resistance in oncogene-driven NSCLC

Authors: Nadine Reischmann, Carolin Schmelas, Miguel Ángel Molina-Vila, Núria Jordana-Ariza, Daniel Kuntze, Silvia García-Roman, Manon A. Simard, Doreen Musch, Christina Esdar, Joachim Albers, Niki Karachaliou

Source: iScience, Vol 26, Iss 7, Pp 107006- (2023)

Subject Terms: Health sciences, Molecular physiology, Cancer, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223010830; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/212794a83ace4b01a781beca9b628143

Comprehensive cross‐platform comparison of methods for non‐invasive EGFR mutation testing: results of the RING observational trial

Authors: Atocha Romero, Eloisa Jantus‐Lewintre, Beatriz García‐Peláez, Ana Royuela, Amelia Insa, Patricia Cruz, Ana Collazo, Javier Pérez Altozano, Oscar Juan Vidal, Pilar Diz, Manuel Cobo, Berta Hernández, Sergio Vázquez Estevez, Gretel Benítez, Maria Guirado, Margarita Majem, Reyes Bernabé, Ana Laura Ortega, Ana Blasco, Joaquim Bosch‐Barrera, Jose M. Jurado, Jorge García González, Santiago Viteri, Carlos Garcia Giron, Bartomeu Massutí, Ana Lopez Martín, Alejandro Rodriguez‐Festa, Silvia Calabuig‐Fariñas, Miguel Ángel Molina‐Vila, Mariano Provencio

Source: Molecular Oncology, Vol 15, Iss 1, Pp 43-56 (2021)

Subject Terms: circulating free DNA, epidermal growth factor receptor, NGS, non‐small‐cell lung cancer, osimertinib, tyrosine kinase inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/fee84be40c92476693b579001138154a