Candidate antibody reference reagents for Chlamydia trachomatis serology

Authors: da Silva, Filomeno Coelho, Kamuyu, Gathoni, Michels, Birgitta, Edney, Jessica, Hassall, Laura, Stickings, Paul, Maharjan, Sunil, Waterboer, Tim, Beddows, Simon

Source: In Journal of Immunological Methods November 2024 534

Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness.

Authors: Sumer, Oyku Ece, Schelzig, Korbinian, Jung, Janine, Li, Xiaoya, Moros, Janina, Schwarzmüller, Luisa, Sen, Ezgi, Karolus, Sabine, Wörner, Angelika, de Melo Costa, Verônica Rodrigues, Nataraj, Nishanth Belugali, Vlachavas, Efstathios-Iason, Gerhäuser, Clarissa, Müller-Decker, Karin, Helm, Dominic, Yarden, Yosef, Michels, Birgitta Elisabeth, Körner, Cindy

Source: BMC Biology; 1/23/2025, Vol. 23 Issue 1, p1-19, 19p

Subject Terms: MEDICAL sciences, BREAST cancer, CANCER-related mortality, ENDOTHELIAL cells, WOMEN'S mortality, BREAST

Cellular and Molecular Changes of Brain Metastases-Associated Myeloid Cells during Disease Progression and Therapeutic Response

Authors: Schulz, Michael, Michels, Birgitta, Niesel, Katja, Stein, Stefan, Farin, Henner, Rödel, Franz, Sevenich, Lisa

Source: In iScience 26 June 2020 23(6)

Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids

Authors: Michels, Birgitta E., Mosa, Mohammed H., Streibl, Barbara I., Zhan, Tianzuo, Menche, Constantin, Abou-El-Ardat, Khalil, Darvishi, Tahmineh, Członka, Ewelina, Wagner, Sebastian, Winter, Jan, Medyouf, Hind, Boutros, Michael, Farin, Henner F.

Source: In Cell Stem Cell 7 May 2020 26(5):782-792

Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency

Authors: Lehle, Anna S. ¹, Farin, Henner F. ^{2, 3, 4}, Marquardt, Benjamin ¹, Michels, Birgitta E. ^{2, 3, 4, 5}, Magg, Thomas ¹, Li, Yue ¹, Liu, Yanshan ¹, Ghalandary, Maryam ¹, Lammens, Katja ⁶, Hollizeck, Sebastian ¹, Rohlfs, Meino ¹, Hauck, Fabian ¹, Conca, Raffaele ¹, Walz, Christoph ⁷, Weiss, Batia ^{8, 9}, Lev, Atar ^{9, 10}, Simon, Amos J. ^{9, 10}, Groß, Olaf ^{11, 12, 22, 23}, Gaidt, Moritz M. ⁶, Hornung, Veit ⁶, Clevers, Hans ¹³, Yazbeck, Nadine ¹⁴, Hanna-Wakim, Rima ¹⁴, Shouval, Dror S. ^{8, 9}, Warner, Neil ¹⁵, Somech, Raz ^{9, 10}, Muise, Aleixo M. ^{15, 16, 17}, Snapper, Scott B. ^{18, 19, 20}, Bufler, Philip ^{1, 21}, Koletzko, Sibylle ¹, Klein, Christoph ^{1, §}, Kotlarz, Daniel ^{1, ∗, §}

Source: In Gastroenterology January 2019 156(1):275-278

Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids

Authors: Mosa, Mohammed H., Nicolle, Ophélie, Maschalidi, Sophia, Sepulveda, Fernando E., Bidaud-Meynard, Aurelien, Menche, Constantin, Michels, Birgitta E., Michaux, Grégoire, de Saint Basile, Geneviève, Farin, Henner F.

Source: In Cellular and Molecular Gastroenterology and Hepatology 2018 6(4):477-493

Human colon organoids reveal distinct physiologic and oncogenic Wnt responses

Authors: Michels, Birgitta E., Mosa, Mohammed H., Grebbin, Britta M., Yepes, Diego, Darvishi, Tahmineh, Hausmann, Johannes, Urlaub, Henning, Zeuzem, Stefan, Kvasnicka, Hans M., Oellerich, Thomas

Source: Journal of experimental medicine. 216(3):704-720

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619232239&indx=1&recIds=ETOCRN619232239

The transcriptional regulator FUBP1 influences disease outcome in murine and human myeloid leukemia

Authors: Hoang, Van, Verma, Divij, Godavarthy, Parimala, Llavona, Pablo, Steiner, Marlene, Gerlach, Katharina, Michels, Birgitta, Bohnenberger, Hanibal, Wachter, Astrid, Oellerich, Thomas, Müller-Kuller, Uta, Weissenberger, Eva, Voutsinas, Jenna, Oehler, Vivian, Farin, Henner, Zörnig, Martin, Krause, Daniela

Source: Leukemia. 33(7):1700-1712

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184152231.0x000001&indx=1&recIds=ETOCvdc_100184152231.0x000001

5'isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1.

Authors: Li, Xiaoya^1,2,3 (AUTHOR), Michels, Birgitta Elisabeth¹ (AUTHOR), Tosun, Oyku Ece^1,4 (AUTHOR), Jung, Janine^1,4 (AUTHOR), Kappes, Jolane¹ (AUTHOR), Ibing, Susanne⁵ (AUTHOR), Nataraj, Nishanth Belugali⁶ (AUTHOR), Sahay, Shashwat⁷ (AUTHOR), Schneider, Martin⁸ (AUTHOR), Wörner, Angelika¹ (AUTHOR), Becki, Corinna¹ (AUTHOR), Ishaque, Naveed⁷ (AUTHOR), Feuerbach, Lars⁵ (AUTHOR), Heßling, Bernd⁸ (AUTHOR), Helm, Dominic⁸ (AUTHOR), Will, Rainer⁸ (AUTHOR), Yarden, Yosef⁶ (AUTHOR), Müller-Decker, Karin⁹ (AUTHOR), Wiemann, Stefan¹ (AUTHOR), Körner, Cindy¹ (AUTHOR) c.koerner@dkfz-heidelberg.de

Source: Journal of Experimental & Clinical Cancer Research (17569966). 6/2/2022, Vol. 41 Issue 1, p1-22. 22p.

Subject Terms: *CANCER patients, *TRIPLE-negative breast cancer, *GENETIC overexpression, *GENE expression, *CELL cycle, *RNA regulation

Clonal heterogeneity in ER+ breast cancer reveals the proteasome and PKC as potential therapeutic targets.

Authors: Beumers, Lukas, Vlachavas, Efstathios-Iason, Borgoni, Simone, Schwarzmüller, Luisa, Penso-Dolfin, Luca, Michels, Birgitta E., Sofyali, Emre, Burmester, Sara, Heiss, Daniela, Wilhelm, Heike, Yarden, Yosef, Helm, Dominic, Will, Rainer, Goncalves, Angela, Wiemann, Stefan

Source: NPJ Breast Cancer; 12/2/2023, Vol. 9 Issue 1, p1-15, 15p

Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1.

Authors: Thüring, Eva-Maria, Hartmann, Christian, Maddumage, Janesha C., Javorsky, Airah, Michels, Birgitta E., Gerke, Volker, Banks, Lawrence, Humbert, Patrick O., Kvansakul, Marc, Ebnet, Klaus

Source: Communications Biology; 7/10/2023, Vol. 6 Issue 1, p1-15, 15p

Subject Terms: INTEGRINS, CELL adhesion, CELL receptors, PEPTIDES, EPITHELIAL cells

3D model for CAR‐mediated cytotoxicity using patient‐derived colorectal cancer organoids

Authors: Schnalzger, Theresa E, Groot, Marnix HP, Zhang, Congcong, Mosa, Mohammed H, Michels, Birgitta E, Röder, Jasmin, Darvishi, Tahmineh, Wels, Winfried S, Farin, Henner F

Source: EMBO journal. 38(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099941119.0x000001&indx=1&recIds=ETOCvdc_100099941119.0x000001

Intestinal brush border formation requires a TMIGD1-based intermicrovillar adhesion complex.

Authors: Hartmann, Christian, Thüring, Eva-Maria, Greune, Lilo, Michels, Birgitta E., Pajonczyk, Denise, Leußink, Sophia, Brinkmann, Frauke, Glaesner-Ebnet, Mark, Wardelmann, Eva, Zobel, Thomas, Schmidt, M. Alexander, Janssen, Klaus-Peter, Gerke, Volker, Ebnet, Klaus

Source: Science Signaling; 9/13/2022, Vol. 15 Issue 751, p1-18, 18p

Subject Terms: CELL anatomy, SCAFFOLD proteins, MICROFILAMENT proteins, INTESTINES, MICROVILLI, EPITHELIAL cells

S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8^+ T cell expansion

Authors: Olesch, Catherine, Sirait-Fischer, Evelyn, Berkefeld, Matthias, Fink, Annika F., Susen, Rosa M., Ritter, Birgit, Michels, Birgitta E., Steinhilber, Dieter, Greten, Florian R., Savai, Rajkumar

Source: Journal of clinical investigation. 130(10):5461-5461

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624826710&indx=1&recIds=ETOCRN624826710

AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer

Authors: Varga, Julia, Nicolas, Adele, Petrocelli, Valentina, Pesic, Marina, Mahmoud, Abdelrahman, Michels, Birgitta E., Etlioglu, Emre, Yepes, Diego, Häupl, Björn, Ziegler, Paul K.

Source: Journal of experimental medicine. 217(10):e20191515-e20191515

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624800690&indx=1&recIds=ETOCRN624800690

PB1808: EPIGENETIC INHIBITOR SCREEN TO IDENTIFY THERAPEUTIC CANDIDATES FOR MNX1‐OVEREXPRESSING AML.

Authors: Kelekci, Simge, Riedel, Anna, Weichenhan, Dieter, Goyal, Ashish, Kelly, Katherine, Baehr, Marion, Michels, Birgitta, Koerner, Cindy, Orzella, Irene, Dunford, James, Lutsik, Pavlo, Wiemann, Stefan, Oppermann, Udo, Plass, Christoph

Source: HemaSphere; 2023 Supplement 3, Vol. 7, p1-2, 2p

Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts

Authors: Berdiel-Acer, Mireia, Maia, Ana, Hristova, Zhivka, Borgoni, Simone, Vetter, Martina, Burmester, Sara, Becki, Corinna, Michels, Birgitta, Abnaof, Khalid, Binenbaum, Ilona, Bethmann, Daniel, Chatziioannou, Aristotelis, Hasmann, Max, Thomssen, Christoph, Espinet, Elisa, Wiemann, Stefan

Source: Oncogene; 20210101, Issue: Preprints p1-16, 16p

Helper T cell immunity in humans with inherited CD4 deficiency

Authors: Guérin, Antoine, Moncada-Vélez, Marcela, Jackson, Katherine, Ogishi, Masato, Rosain, Jérémie, Mancini, Mathieu, Langlais, David, Nunez, Andrea, Webster, Samantha, Goyette, Jesse, Khan, Taushif, Marr, Nico, Avery, Danielle T., Rao, Geetha, Waterboer, Tim, Michels, Birgitta, Neves, Esmeralda, Iracema Morais, Cátia, London, Jonathan, Mestrallet, Stéphanie, Quartier dit Maire, Pierre, Neven, Bénédicte, Rapaport, Franck, Seeleuthner, Yoann, Lev, Atar, Simon, Amos J., Montoya, Jorge, Barel, Ortal, Gómez-Rodríguez, Julio, Orrego, Julio C., L’Honneur, Anne-Sophie, Soudée, Camille, Rojas, Jessica, Velez, Alejandra C., Sereti, Irini, Terrier, Benjamin, Marin, Nancy, García, Luis F., Abel, Laurent, Boisson-Dupuis, Stéphanie, Reis, Joel, Marinho, Antonio, Lisco, Andrea, Faria, Emilia, Goodnow, Christopher C., Vasconcelos, Julia, Béziat, Vivien, Ma, Cindy S., Somech, Raz, Casanova, Jean-Laurent, Bustamante, Jacinta, Franco, Jose Luis, Tangye, Stuart G.

Source: The Journal of Experimental Medicine; May 2024, Vol. 221 Issue: 5 pe20231044-e20231044, 1p

Pooled In Vitroand In VivoCRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids

Authors: Michels, Birgitta E., Mosa, Mohammed H., Streibl, Barbara I., Zhan, Tianzuo, Menche, Constantin, Abou-El-Ardat, Khalil, Darvishi, Tahmineh, Członka, Ewelina, Wagner, Sebastian, Winter, Jan, Medyouf, Hind, Boutros, Michael, Farin, Henner F.

Source: Cell Stem Cell; May 2020, Vol. 26 Issue: 5 p782-792.e7