Somatic mutations and DNA methylation identify a subgroup of poor prognosis within lower‐risk myelodysplastic syndromes

Authors: David Rombaut, Sarah Sandmann, Tobias Tekath, Simon Crouch, Aniek O. deGraaf, Alexandra Smith, Daniel Painter, Olivier Kosmider, Magnus Tobiasson, Andreas Lennartsson, Bert A. van derReijden, Sophie Park, Maud D'Aveni, Borhane Slama, Emmanuelle Clappier, Pierre Fenaux, Lionel Adès, Arjan van deLoosdrecht, Saskia Langemeijer, Argiris Symeonidis, Jaroslav Čermák, Claude Preudhomme, Aleksandar Savic, Ulrich Germing, Reinhard Stauder, David Bowen, Corine vanMarrewijk, Elsa Bernard, Theo deWitte, Julian Varghese, Eva Hellström‐Lindberg, Martin Dugas, Joost Martens, Luca Malcovati, Joop H. Jansen, Michaela Fontenay, MDS‐RIGHT consortium

Source: HemaSphere, Vol 9, Iss 1, Pp n/a-n/a (2025)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/0de63b5bc83940d491a74eb6f7347741

High levels of global hydroxymethylation predict worse overall survival in MDS patients treated with azacitidine

Authors: Francesca Tiso, Florentien E. M. in 't Hout, Ruth Knops, Leonie I. Kroeze, Arno vanRooij, Arjan A. van deLoosdrecht, Theresia M. Westers, Saskia M. C. Langemeijer, Claude Preudhomme, Nicolas Duployez, Pierre Fenaux, Olivier Kosmider, Didier Bouscary, Aniek O. deGraaf, Joost H. A. Martens, Bert A. van derReijden, Lionel Adès, Michaela Fontenay, Joop H. Jansen

Source: HemaSphere, Vol 9, Iss 1, Pp n/a-n/a (2025)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/97257d595ad94e539528299336b20916

Flow cytometric analysis of erythroid precursors and mutational signatures of lower risk myelodysplastic syndromes identify responders to erythroid stimulating agents

Authors: Marco G. Raddi, Sara Bencini, Benedetta Peruzzi, Giorgio Mattiuz, Sven De Pourcq, Michele Tanturli, Nicolas Chapuis, Angela Consagra, Luca Rigodanza, Cristina Amato, Alessandro Sanna, Elena Tofacchi, Enrico Attardi, Sophie Park, Olivier Kosmider, Francesco Annunziato, Michaela Fontenay, Valeria Santini

Source: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-4 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/85af30bcbea34c39b492bf1653a517dd

Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation

Authors: David Rombaut, Carine Lefèvre, Tony Rached, Sabrina Bondu, Anne Letessier, Raphael M. Mangione, Batoul Farhat, Auriane Lesieur-Pasquier, Daisy Castillo-Guzman, Ismael Boussaid, Chloé Friedrich, Aurore Tourville, Magali De Carvalho, Françoise Levavasseur, Marjorie Leduc, Morgane Le Gall, Sarah Battault, Marie Temple, Alexandre Houy, Didier Bouscary, Lise Willems, Sophie Park, Sophie Raynaud, Thomas Cluzeau, Emmanuelle Clappier, Pierre Fenaux, Lionel Adès, Raphael Margueron, Michel Wassef, Samar Alsafadi, Nicolas Chapuis, Olivier Kosmider, Eric Solary, Angelos Constantinou, Marc-Henri Stern, Nathalie Droin, Benoit Palancade, Benoit Miotto, Frédéric Chédin, Michaela Fontenay

Source: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/123566d884df484c9b7e6a5d549470f7

Enhanced fetal hematopoiesis in response to symptomatic SARS-CoV-2 infection during pregnancy

Authors: Mansour Alkobtawi, Qui Trung Ngô, Nicolas Chapuis, Romain H. Fontaine, Mira El Khoury, Matthieu Tihy, Nawa Hachem, Aude Jary, Vincent Calvez, Michaela Fontenay, Vassilis Tsatsaris, Sélim Aractingi, Bénédicte Oulès

Source: Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2730-664X

Access URL: https://doaj.org/article/127cbe8f27fa4f4e9dfcabddb82bc8ae

Immune‐monitoring of myelodysplastic neoplasms: Recommendations from the i4MDS consortium

Authors: Cristina A. Tentori, Lin P. Zhao, Benedetta Tinterri, Kathryn E. Strange, Katharina Zoldan, Konstantinos Dimopoulos, Xingmin Feng, Elena Riva, Benjamin Lim, Yannick Simoni, Vidhya Murthy, Madeline J. Hayes, Antonella Poloni, Eric Padron, Bruno A. Cardoso, Michael Cross, Susann Winter, Aida Santaolalla, Bhavisha A. Patel, Emma M. Groarke, Daniel H. Wiseman, Katy Jones, Lauren Jamieson, Charles Manogaran, Naval Daver, Laura Gallur, Wendy Ingram, P. Brent Ferrell, Katja Sockel, Nicolas Dulphy, Nicolas Chapuis, Anne S. Kubasch, Astrid M. Olsnes, Austin Kulasekararaj, Hugues De Lavellade, Wolfgang Kern, Mieke Van Hemelrijck, Dominique Bonnet, Theresia M. Westers, Sylvie Freeman, Uta Oelschlaegel, David Valcarcel, Marco G. Raddi, Kirsten Grønbæk, Michaela Fontenay, Sanam Loghavi, Valeria Santini, Antonio M. Almeida, Jonathan M. Irish, David A. Sallman, Neal S. Young, Arjan A. van deLoosdrecht, Lionel Adès, Matteo G. Della Porta, Catherine Cargo, Uwe Platzbecker, Shahram Kordasti, i4MDS consortium

Source: HemaSphere, Vol 8, Iss 5, Pp n/a-n/a (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/03709a016c294b7a852299f195f68f9b

S162: LOSS OF HEMATOPOIETIC PROGENITORS HETEROGENEITY IS AN ADVERSE PROGNOSTIC FACTOR IN MYELODYSPLASTIC SYNDROMES

Authors: Charles Dussiau, Thibault Comont, Camille Knosp, Ines Vergnolle, Clotilde Bravetti, Alban Canali, Amandine Houvert, Laetitia Largeaud, Christian Daveaux, Laila Zaroili, Chloe Friedrich, Ismael Boussaid, Loria Zalmai, Carole Almire, Odile Beyne-Rauzy, Lise Willems, Didier Bouscary, Olivier Gandrillon, Michaela Fontenay, Oliver Kosmider, Francois Vergez, Nicolas Chapuis

Source: HemaSphere, Vol 7, p e87989c2 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000967560.87989.c2; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/2a831e7f23544a9fac1e1b8a96ad5747

S163: POLYSOME INTERACTOME IN RPS14-DEFICIENT CELLS REVEALS THE INVOLVEMENT OF THE MRNA DECAY MACHINERY IN TRANSLATION SELECTIVITY.

Authors: Zubaidan Tuerdi, Françoise Levavasseur, Laura Falceto-Font, Malaïka Kinyua, Emilie-Fleur Gautier, Isabelle Dusanter Fourt, Michaela Fontenay, Evelyne Lauret, Ismael Boussaid

Source: HemaSphere, Vol 7, p e99625d2 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000967564.99625.d2; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/f54f20f56b0144aba195537fa652cd4f

S169: MODULATION OF THE IMMUNE LANDSCAPE IN LOWER-RISK MYELODYSPLASTIC SYNDROMES WITH IMETELSTAT-INDUCED TRANSFUSION INDEPENDENCY

Authors: Nicolas Chapuis, David Rombaut, Yannick Simoni, Fei Huang, Michaela Fontenay

Source: HemaSphere, Vol 7, p e889521a (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000967588.88952.1a; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/a4aae1cf0763437fbdc3ddbfecd9a9ad

Correction: Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers

Authors: François-Xavier Danlos, Claudia Grajeda-Iglesias, Sylvère Durand, Allan Sauvat, Mathilde Roumier, Delphine Cantin, Emeline Colomba, Julien Rohmer, Fanny Pommeret, Giulia Baciarello, Christophe Willekens, Marc Vasse, Frank Griscelli, Jean-Eudes Fahrner, Anne-Gaëlle Goubet, Agathe Dubuisson, Lisa Derosa, Nitharsshini Nirmalathasan, Delphine Bredel, Séverine Mouraud, Caroline Pradon, Annabelle Stoclin, Flore Rozenberg, Jérôme Duchemin, Georges Jourdi, Syrine Ellouze, Françoise Levavasseur, Laurence Albigès, Jean-Charles Soria, Fabrice Barlesi, Eric Solary, Fabrice André, Frédéric Pène, Félix Ackerman, Luc Mouthon, Laurence Zitvogel, Aurélien Marabelle, Jean-Marie Michot, Michaela Fontenay, Guido Kroemer

Source: Cell Death and Disease, Vol 15, Iss 2, Pp 1-1 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/398771c440ec490ea228ccac446face7

Hematopoietic differentiation is characterized by a transient peak of entropy at a single-cell level

Authors: Charles Dussiau, Agathe Boussaroque, Mathilde Gaillard, Clotilde Bravetti, Laila Zaroili, Camille Knosp, Chloé Friedrich, Philippe Asquier, Lise Willems, Laurent Quint, Didier Bouscary, Michaela Fontenay, Thibault Espinasse, Adriana Plesa, Pierre Sujobert, Olivier Gandrillon, Olivier Kosmider

Source: BMC Biology, Vol 20, Iss 1, Pp 1-15 (2022)

Subject Terms: Hematopoiesis, Single-cell RNA-seq, Cell-to-cell variability, Entropy, Myelodysplastic syndromes, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/0bd5e386706b47ca9523fe9d092e28ec

Pathophysiology of Myelodysplastic Syndromes

Authors: Michaela Fontenay, Batoul Farhat, Ismael Boussaid

Source: Hemato, Vol 2, Iss 3, Pp 477-495 (2021)

Subject Terms: ineffective erythropoiesis, mutations, deletions, epigenetics, splicing, translation, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2673-6357/2/3/30; https://doaj.org/toc/2673-6357

Access URL: https://doaj.org/article/0e0fa18e16f04c92bcef569f24760129

Venetoclax combination therapy induces deep AML remission with eradication of leukemic stem cells and remodeling of clonal haematopoiesis

Authors: Romain Vazquez, Claire Breal, Loria Zalmai, Chloe Friedrich, Carole Almire, Adrien Contejean, Sylvain Barreau, Eric Grignano, Lise Willems, Benedicte Deau-Fischer, Patricia Franchi, Marguerite Vignon, Justine Decroocq, Rudy Birsen, Lauriane Goldwirt, Sophie Kaltenbach, Lucile Couronne, Michaela Fontenay, Olivier Kosmider, Didier Bouscary, Nicolas Chapuis

Source: Blood Cancer Journal, Vol 11, Iss 3, Pp 1-6 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/ca3e9d4e0c55460db55f6e3d417698f0

Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers

Authors: François-Xavier Danlos, Claudia Grajeda-Iglesias, Sylvère Durand, Allan Sauvat, Mathilde Roumier, Delphine Cantin, Emeline Colomba, Julien Rohmer, Fanny Pommeret, Giulia Baciarello, Christophe Willekens, Marc Vasse, Frank Griscelli, Jean-Eudes Fahrner, Anne-Gaëlle Goubet, Agathe Dubuisson, Lisa Derosa, Nitharsshini Nirmalathasan, Delphine Bredel, Séverine Mouraud, Caroline Pradon, Annabelle Stoclin, Flore Rozenberg, Jérôme Duchemin, Georges Jourdi, Syrine Ellouze, Françoise Levavasseur, Laurence Albigès, Jean-Charles Soria, Fabrice Barlesi, Eric Solary, Fabrice André, Frédéric Pène, Félix Ackerman, Luc Mouthon, Laurence Zitvogel, Aurélien Marabelle, Jean-Marie Michot, Michaela Fontenay, Guido Kroemer

Source: Cell Death and Disease, Vol 12, Iss 3, Pp 1-11 (2021)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/2468f0e5d87e4c05b3cafd9be053d11e

Dynamics of circulating calprotectin accurately predict the outcome of moderate COVID-19 patients

Authors: Nicolas Chapuis, Nusaibah Ibrahimi, Thibaut Belmondo, Claire Goulvestre, Anne-Emmanuelle Berger, Alice-Andrée Mariaggi, Muriel Andrieu, Camille Chenevier-Gobeaux, Arnaud Bayle, Lydia Campos, Cherifa Cheurfa, Richard Chocron, Jean-Luc Diehl, Benoît Doumenc, Jérôme Duchemin, Manon Duprat, Fabien François, Nicolas Gendron, Tristant Mirault, Frédéric Pène, Aurélien Philippe, Fanny Pommeret, Olivier Sanchez, David M. Smadja, Tali-Anne Szwebel, Aymeric Silvin, Florent Ginhoux, Ludovic Lacroix, Gérôme Jules-Clément, Sarobidy Rapeteramana, Colette Mavier, Laura Steller, Barbara Perniconi, Fabrice André, Damien Drubay, Michaela Fontenay, Sophie Hüe, Stéphane Paul, Eric Solary

Source: EBioMedicine, Vol 80, Iss , Pp 104077- (2022)

Subject Terms: COVID-19, Calprotectin, S100A8/A9, Biomarker, Serial measurement, Dynamics, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396422002584; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/b3623b2000f5487f9fbd49f1f4211a88

Bone marrow oxidative stress and specific antioxidant signatures in myelodysplastic syndromes

Authors: Frederic Picou, Christine Vignon, Christelle Debeissat, Sébastien Lachot, Olivier Kosmider, Nathalie Gallay, Amelie Foucault, Marie-Hélène Estienne, Noémie Ravalet, Marie C. Bene, Jorge Domenech, Emmanuel Gyan, Michaela Fontenay, Olivier Herault

Source: Blood Advances, Vol 3, Iss 24, Pp 4271-4279 (2019)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S247395292031716X; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/392527cb66544af0a6ede332d9be87d6

Dual pyroptotic biomarkers predict erythroid response in lower-risk non-del(5q) myelodysplastic syndromes treated with lenalidomide and recombinant erythropoietin

Authors: Chen Wang, Kathy L. McGraw, Amy F. McLemore, Rami Komrokji, Ashley A. Basiorka, Najla Al Ali, Jeffrey E. Lancet, Eric Padron, Olivier Kosmider, Michaela Fontenay, Pierre Fenaux, Alan F. List, David A. Sallman

Source: Haematologica, Vol 107, Iss 3 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10348; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/1398c5b136c14612b740e434506d113d

A Diagnostic Solution for Lupus Anticoagulant Testing in Patients Taking Direct Oral FXa Inhibitors Using DOAC Filter

Authors: Carine Farkh, Syrine Ellouze, Louis Gounelle, Mama Sad Houari, Jérôme Duchemin, Valérie Proulle, Michaela Fontenay, Xavier Delavenne, Georges Jourdi

Source: Frontiers in Medicine, Vol 8 (2021)

Subject Terms: rivaroxaban, lupus anticoaglant, antiphospholipid antibodies, direct oral anitcoagulant, apixaban, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2021.683357/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/b68bcf452eed45ec8d79b4da41113d27

ImmunoCluster provides a computational framework for the nonspecialist to profile high-dimensional cytometry data

Authors: James W Opzoomer, Jessica A Timms, Kevin Blighe, Thanos P Mourikis, Nicolas Chapuis, Richard Bekoe, Sedigeh Kareemaghay, Paola Nocerino, Benedetta Apollonio, Alan G Ramsay, Mahvash Tavassoli, Claire Harrison, Francesca Ciccarelli, Peter Parker, Michaela Fontenay, Paul R Barber, James N Arnold, Shahram Kordasti

Source: eLife, Vol 10 (2021)

Subject Terms: ImmunoCluster, framework, immunology, computational biology, cytometry, immune monitoring, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/62915; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/78033dd608be40de9a83b21d8e652c8c

APR-246 induces early cell death by ferroptosis in acute myeloid leukemia

Authors: Rudy Birsen, Clement Larrue, Justine Decroocq, Natacha Johnson, Nathan Guiraud, Mathilde Gotanegre, Lilia Cantero-Aguilar, Eric Grignano, Tony Huynh, Michaela Fontenay, Olivier Kosmider, Patrick Mayeux, Nicolas Chapuis, Jean Emmanuel Sarry, Jerome Tamburini, Didier Bouscary

Source: Haematologica, Vol 107, Iss 2 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10139; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/450db381926d46e993daececdc3996e8