Stromal lymphocytes are associated with upgrade of B3 breast lesions

Authors: Tanjina Kader, Elena Provenzano, Madawa W. Jayawardana, Shona Hendry, Jia-Min Pang, Kenneth Elder, David J. Byrne, Lauren Tjoeka, Helen ML. Frazer, Eloise House, Sureshni I. Jayasinghe, Holly Keane, Anand Murugasu, Neeha Rajan, Islam M. Miligy, Michael Toss, Andrew R. Green, Emad A. Rakha, Stephen B. Fox, G. Bruce Mann, Ian G. Campbell, Kylie L. Gorringe

Source: Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)

Subject Terms: Atypical ductal hyperplasia, Lesions of uncertain malignant potential, B3 lesions, Tumour infiltrating lymphocytes, Stromal lymphocytes, Upgrade, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1465-542X

Access URL: https://doaj.org/article/b48a3f6e9ea54a189ccefd102db6473b

AI-enabled routine H&E image based prognostic marker for early-stage luminal breast cancer

Authors: Noorul Wahab, Michael Toss, Islam M. Miligy, Mostafa Jahanifar, Nehal M. Atallah, Wenqi Lu, Simon Graham, Mohsin Bilal, Abhir Bhalerao, Ayat G. Lashen, Shorouk Makhlouf, Asmaa Y. Ibrahim, David Snead, Fayyaz Minhas, Shan E. Ahmed Raza, Emad Rakha, Nasir Rajpoot

Source: npj Precision Oncology, Vol 7, Iss 1, Pp 1-13 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/a9e6a8e5c93b4edab4db8a7980977476

AI‐based intra‐tumor heterogeneity score of Ki67 expression as a prognostic marker for early‐stage ER+/HER2− breast cancer

Authors: Wenqi Lu, Ayat G Lashen, Noorul Wahab, Islam M Miligy, Mostafa Jahanifar, Michael Toss, Simon Graham, Mohsin Bilal, Abhir Bhalerao, Nehal M Atallah, Shorouk Makhlouf, Asmaa Y Ibrahim, David Snead, Fayyaz Minhas, Shan E Ahmed Raza, Emad Rakha, Nasir Rajpoot

Source: The Journal of Pathology: Clinical Research, Vol 10, Iss 1, Pp n/a-n/a (2024)

Subject Terms: AI based prognostic biomarkers, computational pathology, Ki67 expression, luminal breast cancer, Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/2056-4538

Access URL: https://doaj.org/article/6a155cf9d05147a98b8a08c72dc26ccc

Immune infiltration, aggressive pathology, and poor survival outcomes in RECQL helicase deficient breast cancers

Authors: Ayat Lashen, Abdulbaqi Al-Kawaz, Jennie N Jeyapalan, Shatha Alqahtani, Ahmed Shoqafi, Mashael Algethami, Michael Toss, Andrew R Green, Nigel P Mongan, Sudha Sharma, Mohammad R Akbari, Emad A Rakha, Srinivasan Madhusudan

Source: Neoplasia: An International Journal for Oncology Research, Vol 47, Iss , Pp 100957- (2024)

Subject Terms: RECQL, CD8, FOXP3, IL17, PDL1, PD1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558623000805; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/49f4f85691f14003931c5bd5105aab22

RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer

Authors: Marina Ciscar, Eva M Trinidad, Gema Perez‐Chacon, Mansour Alsaleem, Maria Jimenez, Maria J Jimenez‐Santos, Hector Perez‐Montoyo, Adrian Sanz‐Moreno, Andrea Vethencourt, Michael Toss, Anna Petit, Maria T Soler‐Monso, Victor Lopez, Jorge Gomez‐Miragaya, Clara Gomez‐Aleza, Lacey E Dobrolecki, Michael T Lewis, Alejandra Bruna, Silvana Mouron, Miguel Quintela‐Fandino, Fatima Al‐Shahrour, Antonio Martinez‐Aranda, Angels Sierra, Andrew R Green, Emad Rakha, Eva Gonzalez‐Suarez

Source: EMBO Molecular Medicine, Vol 15, Iss 4, Pp 1-12 (2023)

Subject Terms: breast cancer patient‐derived xenografts, ER negative breast cancer, menopause, pharmacological RANKL inhibitors, RANK‐RANKL, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/1a7e932a6a184ce6a384d4a58e43a0be

Semantic annotation for computational pathology: multidisciplinary experience and best practice recommendations

Authors: Noorul Wahab, Islam M Miligy, Katherine Dodd, Harvir Sahota, Michael Toss, Wenqi Lu, Mostafa Jahanifar, Mohsin Bilal, Simon Graham, Young Park, Giorgos Hadjigeorghiou, Abhir Bhalerao, Ayat G Lashen, Asmaa Y Ibrahim, Ayaka Katayama, Henry O Ebili, Matthew Parkin, Tom Sorell, Shan E Ahmed Raza, Emily Hero, Hesham Eldaly, Yee Wah Tsang, Kishore Gopalakrishnan, David Snead, Emad Rakha, Nasir Rajpoot, Fayyaz Minhas

Source: The Journal of Pathology: Clinical Research, Vol 8, Iss 2, Pp 116-128 (2022)

Subject Terms: whole‐slide images, computational pathology, annotations, guidelines, Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/2056-4538

Access URL: https://doaj.org/article/0ab322726d414a3280ea866dedb9d11e