Novel translational mouse models of metabolic dysfunction-associated steatotic liver disease comparable to human MASLD with severe obesity

Authors: Katharina L. Hupa-Breier, Heiko Schenk, Alejandro Campos-Murguia, Freya Wellhöner, Benjamin Heidrich, Janine Dywicki, Björn Hartleben, Clara Böker, Julian Mall, Christoph Terkamp, Ludwig Wilkens, Friedrich Becker, Karl Lenhard Rudolph, Michael Peter Manns, Young-Seon Mederacke, Silke Marhenke, Hanna Redeker, Maren Lieber, Konstantinos Iordanidis, Richard Taubert, Heiner Wedemeyer, Fatih Noyan, Matthias Hardtke-Wolenski, Elmar Jaeckel

Source: Molecular Metabolism, Vol 93, Iss , Pp 102104- (2025)

Subject Terms: Metabolic dysfunction-associated steatotic liver disease, Metabolic syndrome, Mouse model, Kidney injury, Non-alcoholic fatty liver disease, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877825000110; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/a1a31a4aae184c21ba4d6c5dc40e7cf0

Canine real-time detection of SARS-CoV-2 infections in the context of a mass screening event

Authors: Holger Andreas Volk, Tobias Welte, Claudia Schulz, Andreas Nitsche, Thomas Illig, Lothar Kreienbrock, Maren von Köckritz-Blickwede, Michael Peter Manns, Nele Alexandra ten Hagen, Friederike Twele, Sebastian Meller, Lisa Wijnen, Clara Schoneberg, Albert Osterhaus, Anna-Lena Boeck, Konstantin Boeck, Viktoria Bonda, Veronika Pilchová, Franziska Karola Kaiser, Mariana Gonzalez Hernandez, Hans Ebbers, Julia Hinsenkamp, Isabell Pink, Nora Drick, Andreas Puyskens, Christiane Ernst, Michael Engels, Esther Schalke

Source: BMJ Global Health, Vol 7, Iss 11 (2022)

Subject Terms: Medicine (General), R5-920, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://gh.bmj.com/content/7/11/e010276.full; https://doaj.org/toc/2059-7908

Access URL: https://doaj.org/article/3c6da634b23f4f49811e9512da3361d3

PD-1/CTLA-4 blockade leads to expansion of CD8+PD-1int TILs and results in tumor remission in experimental liver cancer

Authors: Sandra Bufe, Artur Zimmermann, Sarina Ravens, Immo Prinz, Laura Elisa Buitrago-Molina, Robert Geffers, Norman Woller, Florian Kühnel, Steven R. Talbot, Fatih Noyan, Michael Peter Manns, Heiner Wedemeyer, Matthias Hardtke-Wolenski, Elmar Jaeckel, Ana C. Davalos-Misslitz

Source: Liver Cancer (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/526899; https://doaj.org/toc/2235-1795; https://doaj.org/toc/1664-5553

Access URL: https://doaj.org/article/965c2a4212154815948f7cc4a347137a

Scent dog identification of SARS-CoV-2 infections in different body fluids

Authors: Paula Jendrny, Friederike Twele, Sebastian Meller, Claudia Schulz, Maren von Köckritz-Blickwede, Albertus Dominicus Marcellinus Eras Osterhaus, Hans Ebbers, Janek Ebbers, Veronika Pilchová, Isabell Pink, Tobias Welte, Michael Peter Manns, Anahita Fathi, Marylyn Martina Addo, Christiane Ernst, Wencke Schäfer, Michael Engels, Anja Petrov, Katharina Marquart, Ulrich Schotte, Esther Schalke, Holger Andreas Volk

Source: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-14 (2021)

Subject Terms: SARS-CoV-2, Volatile organic compounds, Scent detection dogs, Saliva, Urine, Sweat, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/d55c8f8b8773480ca8b45e38b8f63b36

Scent dog identification of samples from COVID-19 patients – a pilot study

Authors: Paula Jendrny, Claudia Schulz, Friederike Twele, Sebastian Meller, Maren von Köckritz-Blickwede, Albertus Dominicus Marcellinus Erasmus Osterhaus, Janek Ebbers, Veronika Pilchová, Isabell Pink, Tobias Welte, Michael Peter Manns, Anahita Fathi, Christiane Ernst, Marylyn Martina Addo, Esther Schalke, Holger Andreas Volk

Source: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-7 (2020)

Subject Terms: COVID-19, SARS-CoV-2, Volatile organic compounds, Scent detection dogs, Olfactory detection, Saliva, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12879-020-05281-3; https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/fe50786626a64226b630074cbf139ead

Discrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs

Authors: Nele Alexandra ten Hagen, Friederike Twele, Sebastian Meller, Paula Jendrny, Claudia Schulz, Maren von Köckritz-Blickwede, Ab Osterhaus, Hans Ebbers, Isabell Pink, Tobias Welte, Michael Peter Manns, Thomas Illig, Anahita Fathi, Marylyn Martina Addo, Andreas Nitsche, Andreas Puyskens, Janine Michel, Eva Krause, Rosina Ehmann, Albrecht von Brunn, Christiane Ernst, Katrin Zwirglmaier, Roman Wölfel, Alexandra Nau, Eva Philipp, Michael Engels, Esther Schalke, Holger Andreas Volk

Source: Frontiers in Medicine, Vol 8 (2021)

Subject Terms: canine, volatile organic compound (VOC), COVID-19, screening test, coronavirus, SARS-CoV-2, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2021.749588/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/d29ef6ecffdd4eefaba7e89d9babf710

Ex Vivo/In vivo Gene Editing in Hepatocytes Using 'All-in-One' CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template

Authors: Simon Alexander Krooss, Zhen Dai, Florian Schmidt, Alice Rovai, Julia Fakhiri, Akshay Dhingra, Qinggong Yuan, Taihua Yang, Asha Balakrishnan, Lars Steinbrück, Sangar Srivaratharajan, Michael Peter Manns, Axel Schambach, Dirk Grimm, Jens Bohne, Amar Deep Sharma, Hildegard Büning, Michael Ott

Source: iScience, Vol 23, Iss 1, Pp - (2020)

Subject Terms: Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004219305097; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/8489088995c34cbe8ba0b1a8c77f10b1

Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy

Authors: Chai Fen Soon, Shihong Zhang, Pothakamuri Venkata Suneetha, Dinler Amaral Antunes, Michael Peter Manns, Solaiman Raha, Christian Schultze-Florey, Immo Prinz, Heiner Wedemeyer, Margaret Sällberg Chen, Markus Cornberg

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: CD8+ T cells, cross-reactivity, T cell therapy, immunotherapy, T cell receptor (TCR), TCR redirection, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.02076/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/400fb658755a4169a0845c8b630f7822

Sustained impact of nosocomial-acquired spontaneous bacterial peritonitis in different stages of decompensated liver cirrhosis.

Authors: Markus Kimmann, Tammo Lambert Tergast, Marie Schultalbers, Hans Laser, Svetlana Gerbel, Michael Peter Manns, Markus Cornberg, Benjamin Maasoumy

Source: PLoS ONE, Vol 14, Iss 8, p e0220666 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6606e6c0ff494a2b9398066fdac6ba1c

Application of the Liver Maximum Function Capacity Test in Acute Liver Failure: A Helpful Tool for Decision-Making in Liver Transplantation?

Authors: Florian Wolfgang Rudolf Vondran, Carsten Schumacher, Kai Johanning, Björn Hartleben, Wolfgang Knitsch, Olaf Wiesner, Elmar Jaeckel, Michael Peter Manns, Juergen Klempnauer, Hueseyin Bektas, Frank Lehner

Source: Case Reports in Transplantation, Vol 2016 (2016)

Subject Terms: Surgery, RD1-811

File Description: electronic resource

Relation: https://doaj.org/toc/2090-6943; https://doaj.org/toc/2090-6951

Access URL: https://doaj.org/article/f75c15579d1645e3afb2ed373925aec5

Type I Interferon Elevates Co-regulatory Receptor Expression on CMV- and EBV-specific CD8 T cells in Chronic Hepatitis C

Authors: Solomon eOwusu Sekyere, Pothakamuri Venkata Suneetha, Svenja eHardtke, Christine Susanne Falk, Julia eHengst, Michael Peter Manns, Markus eCornberg, Heiner eWedemeyer, Verena eSchlaphoff

Source: Frontiers in Immunology, Vol 6 (2015)

Subject Terms: Cytokines, Hepatitis C, PD-1, T cell regulation, TIM-3, 2B4, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00270/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/65cf6631831a4398862f48174bc90a31

Target Proteins in Human Autoimmunity: Cytochromes P450 and Udp-Glycoronosyltransferases

Authors: Petra Obermayer-Straub, Christian Peer Strassburg, Michael Peter Manns

Source: Canadian Journal of Gastroenterology, Vol 14, Iss 5, Pp 429-439 (2000)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/0835-7900

Access URL: https://doaj.org/article/89b725110ba8431893141ab4f0e94470

Increased HEV seroprevalence in patients with autoimmune hepatitis.

Authors: Sven Pischke, Anett Gisa, Pothakamuri Venkata Suneetha, Steffen Björn Wiegand, Richard Taubert, Jerome Schlue, Karsten Wursthorn, Heike Bantel, Regina Raupach, Birgit Bremer, Behrend Johann Zacher, Reinhold Ernst Schmidt, Michael Peter Manns, Kinan Rifai, Torsten Witte, Heiner Wedemeyer

Source: PLoS ONE, Vol 9, Iss 1, p e85330 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3897432?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/9579bd58ac334f7fb615dd715bc22ade

Absence of chronic hepatitis E in a German cohort of common variable immunodeficiency patients

Authors: Sven Pischke, Ruediger Horn-Wichmann, Diana Ernst, Bjoern Georg Meyer, Regina Raupach, Gerrit Ahrenstorf, Reinhold Ernst Schmidt, Michael Peter Manns, Torsten Witte, Heiner Wedemeyer

Source: Infectious Disease Reports, Vol 4, Iss 2, Pp e28-e28 (2012)

Subject Terms: hepatitis E, common variable immunodeficiency, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://www.pagepress.org/journals/index.php/idr/article/view/3777; https://doaj.org/toc/2036-7430; https://doaj.org/toc/2036-7449

Access URL: https://doaj.org/article/8cccfa1e7be044efaf64da9134440492

Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells.

Authors: Verena Schlaphoff, Sebastian Lunemann, Pothakamuri Venkata Suneetha, Jerzy Jaroszewicz, Jan Grabowski, Julia Dietz, Fabian Helfritz, Hueseyin Bektas, Christoph Sarrazin, Michael Peter Manns, Markus Cornberg, Heiner Wedemeyer

Source: PLoS Pathogens, Vol 7, Iss 5, p e1002045 (2011)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3098233?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/2834350100cf463fa8f1f03781eda727

Patients with Chronic Hepatitis C - Who Should Not Be Treated?

Authors: Andreas Schüler, Michael Peter Manns

Source: Canadian Journal of Gastroenterology, Vol 14, Iss Suppl B, Pp 63B-67B (2000)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/0835-7900

Access URL: https://doaj.org/article/212e0111ad9b4d738e508f15b1ff72e5