The phospholipase A of Neisseria gonorrhoeae lyses eukaryotic membranes and is necessary for survival in neutrophils and cervical epithelial cells

Authors: Michael A. Apicella, Jennifer L. Edwards, Margaret R. Ketterer, David S. Weiss, Yuan Zhang, Freda E.-C. Jen, Michael P. Jennings

Source: mBio, Vol 15, Iss 10 (2024)

Subject Terms: Neisseria gonorrhoeae, phospholipase A, neutrophils, cervical epithelial cells, hemolysis, gonorrhea, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/b83cc134a9e54f84ae257adcedf8062e

The essential malaria protein PfCyRPA targets glycans to invade erythrocytes

Authors: Christopher J. Day, Paola Favuzza, Sabrina Bielfeld, Thomas Haselhorst, Leonie Seefeldt, Julia Hauser, Lucy K. Shewell, Christian Flueck, Jessica Poole, Freda E.-C. Jen, Anja Schäfer, Jean-Pierre Dangy, Tim-W. Gilberger, Camila Tenorio França, Manoj T. Duraisingh, Marco Tamborrini, Nicolas M.B. Brancucci, Christof Grüring, Michael Filarsky, Michael P. Jennings, Gerd Pluschke

Source: Cell Reports, Vol 43, Iss 4, Pp 114012- (2024)

Subject Terms: CP: Microbiology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724003401; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/b1552435879b4808a30ae832a3d6786d

Phasevarions in Haemophilus influenzae biogroup aegyptius control expression of multiple proteins

Authors: Greg Tram, Freda E.-C. Jen, Zachary N. Phillips, John F. Lancashire, Jamie Timms, Jessica Poole, Michael P. Jennings, John M. Atack

Source: Microbiology Spectrum, Vol 12, Iss 1 (2024)

Subject Terms: phase variation, phasevarion, Haemophilus influenzae biogroup aegyptius, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/bb3c4b220b9b4758b57325e22dd20940

Analysis of Bacterial Phosphorylcholine-Related Genes Reveals an Association between Type-Specific Biosynthesis Pathways and Biomolecules Targeted for Phosphorylcholine Modification

Authors: Yuan Zhang, Freda E.-C. Jen, Jennifer L. Edwards, Michael P. Jennings

Source: Microbiology Spectrum, Vol 11, Iss 4 (2023)

Subject Terms: phosphorylcholine, ChoP, phosphatidylcholine, phosphoethanolamine, bacterial virulence, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/a7baa9770efb479ab5d93dd074909afa

New Perspectives on Escherichia coli Signal Peptidase I Substrate Specificity: Investigating Why the TasA Cleavage Site Is Incompatible with LepB Cleavage

Authors: Joanna E. Musik, Jessica Poole, Christopher J. Day, Thomas Haselhorst, Freda E.-C. Jen, Thomas Ve, Veronika Masic, Michael P. Jennings, Yaramah M. Zalucki

Source: Microbiology Spectrum, Vol 11, Iss 3 (2023)

Subject Terms: LepB, secretion, signal peptidase I, substrate specificity, TasA, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/d352345c81ca42e69915574c0c5eb31d

N-glycolylneuraminic acid as a carbohydrate cancer biomarker

Authors: Jing Wang, Lucy K. Shewell, Christopher J. Day, Michael P. Jennings

Source: Translational Oncology, Vol 31, Iss , Pp 101643- (2023)

Subject Terms: N-glycolylneuraminic acid, Neu5Gc, Cancer biomarker, Detection, Prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523323000293; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/4a98c900b3e543ab8cfa59e2d9185040

N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease

Authors: Lucy K. Shewell, Christopher J. Day, Jamie R. Kutasovic, Jodie L. Abrahams, Jing Wang, Jessica Poole, Colleen Niland, Kaltin Ferguson, Jodi M. Saunus, Sunil R. Lakhani, Mark von Itzstein, James C. Paton, Adrienne W. Paton, Michael P. Jennings

Source: BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)

Subject Terms: N-glycolylneuraminic acid, Neu5Gc, Biomarker, Breast cancer, Diagnostic, Ovarian cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/092d74e4677c4563b6a55618a5661257

Calcium Contributes to Polarized Targeting of HIV Assembly Machinery by Regulating Complex Stability

Authors: Chandan Kishor, Belinda L. Spillings, Johana Luhur, Corinne A. Lutomski, Chi-Hung Lin, William J. McKinstry, Christopher J. Day, Michael P. Jennings, Martin F. Jarrold, Johnson Mak

Source: JACS Au, Vol 2, Iss 2, Pp 522-530 (2022)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2691-3704

Access URL: https://doaj.org/article/386c1c4b964d496ea183fa41ea201b64

Adherence of Nontypeable Haemophilus influenzae to Cells and Substrates of the Airway Is Differentially Regulated by Individual ModA Phasevarions

Authors: Preeti Garai, John M. Atack, Brandon M. Wills, Michael P. Jennings, Lauren O. Bakaletz, Kenneth L. Brockman

Source: Microbiology Spectrum, Vol 11, Iss 1 (2023)

Subject Terms: ModA phasevarion, NTHi, adherence, respiratory tract substrates, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/c17d75c5b6024cfdaf3b36babdf24c7b

Pneumococcal Phasevarions Control Multiple Virulence Traits, Including Vaccine Candidate Expression

Authors: Zachary N. Phillips, Claudia Trappetti, Annelies Van Den Bergh, Gael Martin, Ainslie Calcutt, Victoria Ozberk, Patrice Guillon, Manisha Pandey, Mark von Itzstein, W. Edward Swords, James C. Paton, Michael P. Jennings, John M. Atack

Source: Microbiology Spectrum, Vol 10, Iss 3 (2022)

Subject Terms: phasevarion, phase variation, Streptococcus pneumoniae, vaccine, epigenetic regulation, pneumococcus, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/68f9c1ea19634bfb9653d1784a3d28cf

Complement Receptor 3 Mediates HIV-1 Transcytosis across an Intact Cervical Epithelial Cell Barrier: New Insight into HIV Transmission in Women

Authors: Christopher J. Day, Rachael L. Hardison, Belinda L. Spillings, Jessica Poole, Joseph A. Jurcisek, Johnson Mak, Michael P. Jennings, Jennifer L. Edwards

Source: mBio, Vol 13, Iss 1 (2022)

Subject Terms: HIV, complement receptor 3, cervical epithelial cells, transcytosis, carbamazepine, methyldopa, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/26d8314ea5da4c688c440ec560c6d217

Streptococcus suis Encodes Multiple Allelic Variants of a Phase-Variable Type III DNA Methyltransferase, ModS, That Control Distinct Phasevarions

Authors: Greg Tram, Freda E.-C. Jen, Zachary N. Phillips, Jamie Timms, Asma-Ul Husna, Michael P. Jennings, Patrick J. Blackall, John M. Atack

Source: mSphere, Vol 6, Iss 3 (2021)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/3e51077cd21f4c13ae1cb07ba7534ec0

Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2–ACE2 Receptor Interactions

Authors: Christopher J. Day, Benjamin Bailly, Patrice Guillon, Larissa Dirr, Freda E.-C. Jen, Belinda L. Spillings, Johnson Mak, Mark von Itzstein, Thomas Haselhorst, Michael P. Jennings

Source: mBio, Vol 12, Iss 2 (2021)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/2b06afb56d02402cb0d88feb912f1af0

The Lst Sialyltransferase of Neisseria gonorrhoeae Can Transfer Keto-Deoxyoctanoate as the Terminal Sugar of Lipooligosaccharide: a Glyco-Achilles Heel That Provides a New Strategy for Vaccines to Prevent Gonorrhea

Authors: Freda E.-C. Jen, Margaret R. Ketterer, Evgeny A. Semchenko, Christopher J. Day, Kate L. Seib, Michael A. Apicella, Michael P. Jennings

Source: mBio, Vol 12, Iss 2 (2021)

Subject Terms: Neisseria gonorrhea, lipooligosaccharide (LOS), keto-deoxyoctanoate (KDO), gonococcal vaccine, N-acetylneuraminic acid (Neu5Ac), sialic acid, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/e792e6f0b6e749d4b2e0efbf84976f51

Discovery of Bacterial Fimbria–Glycan Interactions Using Whole-Cell Recombinant Escherichia coli Expression

Authors: Christopher J. Day, Alvin W. Lo, Lauren E. Hartley-Tassell, M. Pilar Argente, Jessica Poole, Nathan P. King, Joe Tiralongo, Michael P. Jennings, Mark A. Schembri

Source: mBio, Vol 12, Iss 1 (2021)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2161-2129; https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/093d6be022874964af90f81d63861f6b

Stereoselective OsO4-mediated dihydroxylation of β-substituted α-trialkylsilyl-β,γ-unsaturated esters

Authors: Anna C. Seal, Michael P. Jennings

Source: Results in Chemistry, Vol 3, Iss , Pp 100250- (2021)

Subject Terms: Allylsilane, Dihydroxylation, Natural products, Olefination, Diastereoselective synthesis, Chemistry, QD1-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211715621001557; https://doaj.org/toc/2211-7156

Access URL: https://doaj.org/article/f35a48c8c5e8410a87c28e5865ff6a7f

The Nontypeable Haemophilus influenzae Major Adhesin Hia Is a Dual-Function Lectin That Binds to Human-Specific Respiratory Tract Sialic Acid Glycan Receptors

Authors: John M. Atack, Christopher J. Day, Jessica Poole, Kenneth L. Brockman, Jamie R. L. Timms, Linda E. Winter, Thomas Haselhorst, Lauren O. Bakaletz, Stephen J. Barenkamp, Michael P. Jennings

Source: mBio, Vol 11, Iss 6 (2020)

Subject Terms: COPD, NTHi, adhesin, autotransporter proteins, bacterial pathogen, glycan, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/b2682d6d2df04df69b1bd523da687501

Systematic Analysis of REBASE Identifies Numerous Type I Restriction-Modification Systems with Duplicated, Distinct hsdS Specificity Genes That Can Switch System Specificity by Recombination

Authors: John M. Atack, Chengying Guo, Thomas Litfin, Long Yang, Patrick J. Blackall, Yaoqi Zhou, Michael P. Jennings

Source: mSystems, Vol 5, Iss 4 (2020)

Subject Terms: hsdS, phase variation, phasevarion, restriction-modification, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/91693bc9f96b4c51acd0bbffc06d674a

The glycointeractome of serogroup B Neisseria meningitidis strain MC58

Authors: Tsitsi D. Mubaiwa, Lauren E. Hartley-Tassell, Evgeny A. Semchenko, Freda. E.-C. Jen, Yogitha N. Srikhanta, Christopher J. Day, Michael P. Jennings, Kate L. Seib

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/8379f6aa7cdc420585fd4f2d973b774a

The ModA2 Phasevarion of nontypeable Haemophilus influenzae Regulates Resistance to Oxidative Stress and Killing by Human Neutrophils

Authors: Kenneth L. Brockman, M. Taylor Branstool, John M. Atack, Frank Robledo-Avila, Santiago Partida-Sanchez, Michael P. Jennings, Lauren O. Bakaletz

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9b46a41b92a6434a906b238023a63cda