Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin

Authors: Angela M Phillips, Michael B Doud, Luna O Gonzalez, Vincent L Butty, Yu-Shan Lin, Jesse D Bloom, Matthew D Shoulders

Source: eLife, Vol 7 (2018)

Subject Terms: influenza, evolution, proteostasis, protein folding, unfolded protein response, membrane protein, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/38795; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/bde65080ca6046dca52b4266f86786eb

Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA.

Authors: Orr Ashenberg, Jai Padmakumar, Michael B Doud, Jesse D Bloom

Source: PLoS Pathogens, Vol 13, Iss 3, p e1006288 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5383324?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/1ca1d5f6cd6e453ab63832fb53cfdf83

Complete mapping of viral escape from neutralizing antibodies.

Authors: Michael B Doud, Scott E Hensley, Jesse D Bloom

Source: PLoS Pathogens, Vol 13, Iss 3, p e1006271 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5363992?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/e6ff75ab62b2430ab1d93bff33dab506

Competition-driven eco-evolutionary feedback reshapes bacteriophage lambda’s fitness landscape and enables speciation

Authors: Michael B. Doud, Animesh Gupta, Victor Li, Sarah J. Medina, Caesar A. De La Fuente, Justin R. Meyer

Source: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f05ce5ec0d4d47bea8fccdb8e6850b5b

phydms: software for phylogenetic analyses informed by deep mutational scanning

Authors: Sarah K. Hilton, Michael B. Doud, Jesse D. Bloom

Source: PeerJ, Vol 5, p e3657 (2017)

Subject Terms: Deep mutational scanning, Phylogenetics, ExpCM, Codon substitution model, Diversifying selection, Positive selection, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/3657.pdf; https://peerj.com/articles/3657/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/5bcdaa8ba5e64fc8abc1ab6350f1143b

How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin

Authors: Michael B. Doud, Juhye M. Lee, Jesse D. Bloom

Source: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/876257bdebd1481d98820158c8928e1b

Accurate Measurement of the Effects of All Amino-Acid Mutations on Influenza Hemagglutinin

Authors: Michael B. Doud, Jesse D. Bloom

Source: Viruses, Vol 8, Iss 6, p 155 (2016)

Subject Terms: influenza, hemagglutinin, mutational tolerance, deep mutational scanning, evolution, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.mdpi.com/1999-4915/8/6/155; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/23d76d6f332b4aa08cd228040dc9dca3